公开(公告)号：DE10154601B4

公开(公告)日：2007-02-22

申请号：DE10154601

申请日：2001-11-07

Applicant: AGILENT TECHNOLOGIES INC

Inventor： BRENNEN REID A ,  YIN HONGFENG ,  KILLEEN KEVIN P

IPC: B81C1/00 ,  B01D57/00 ,  B05B5/025 ,  B23K26/00 ,  B81B1/00 ,  C12M1/00 ,  G01N27/62 ,  H01J49/04

公开(公告)号：GB2446254B8

公开(公告)日：2011-11-23

申请号：GB0800269

申请日：2008-01-08

Applicant: AGILENT TECHNOLOGIES INC

Inventor： BEERLING TIMOTHY ,  KRAICZEK KARSTEN G ,  BRENNEN REID A

IPC: B81C1/00 ,  B82B3/00 ,  G01N30/60

Abstract: In some embodiments of the present invention, the buried silicon oxide technology is employed in the fabrication of fluid channels, particularly nanochannels. For example, a fluid channel can be made in a buried silicon oxide layer by etching the buried oxide layer with a method that selectively removes silicon oxide but not silicon. Thus, one dimension of the resulting fluid channel is limited by the thickness of the buried oxide layer. It is possible to manufacture a very thin buried oxide layer with great precision, thus a nanochannel can be fabricated in a controlled manner. Moreover, in addition to buried oxide, any pairs of substances with a high etch ratio with respect to each other can be used in the same way. Further provided are the fluid channels, apparatuses, devices and systems comprising the fluid channels, and uses thereof.

公开(公告)号：DE10309583A1

公开(公告)日：2003-12-11

申请号：DE10309583

申请日：2003-03-05

Applicant: AGILENT TECHNOLOGIES INC

Inventor： BRENNEN REID A ,  KILLEEN KEVIN PATRICK ,  YIN HONAFENA

IPC: B01L3/00 ,  B01L3/02 ,  G01N30/46 ,  G01N30/60 ,  G01N30/72 ,  B01J19/00 ,  G01N27/62 ,  H01J49/00

Abstract: A microanalytical device is provided for conducting multiple chemical and/or biochemical reactions and analyzing multiple sample fluids in parallel using minute volumes of reaction or sample fluid. The devices comprises a well plate with an integrated microfluidic system containing processing compartments such as microcavities, microchannels and the like, that are in fluid communication with electrospray emitters. The novel microanalytical device can be used in a variety of chemical and biochemical contexts, including mass spectroscopy, chromatographic, electrophoretic and electrochromatographic separations, screening and diagnostics, and chemical and biochemical synthesis. The devices may be formed from a material that is thermally and chemically stable and resistant to biofouling, significantly reducing electroosmotic flow and unwanted adsorption of solute.

公开(公告)号：DE19952764C2

公开(公告)日：2003-02-27

申请号：DE19952764

申请日：1999-11-02

Applicant: AGILENT TECHNOLOGIES INC

Inventor： SWEDBERG SALLY A ,  BRENNEN REID A

IPC: B01L3/00 ,  G01N35/08 ,  B01J19/00 ,  B81B7/00

Abstract: A microanalysis device having a plurality of sample processing compartments is described for use in liquid phase analysis. A microanalysis device system, comprising a plurality of interconnected microanalysis devices. The device is formed by microfabrication of microstructures in novel support substrates. The invention herein can be used for the analysis of small and/or macromolecular and/or other solutes in the liquid phase.

公开(公告)号：DE10122133A1

公开(公告)日：2002-01-10

申请号：DE10122133

申请日：2001-05-08

Applicant: AGILENT TECHNOLOGIES INC

Inventor： BRENNEN REID A ,  GOOR ANTONIUS A A M VAN DE

IPC: B01L3/00 ,  B81B1/00 ,  B81B7/02 ,  G01N27/447 ,  G01N35/08 ,  B01J19/00

Abstract: An integrated analytic microsystem comprising a micro-fluidic component carrying a fluid of interest coupled to an electronic component including a signal measurement and processing circuit, to evaluate a property of the fluid, is new.

公开(公告)号：EP3047266A4

公开(公告)日：2017-04-12

申请号：EP14849464

申请日：2014-08-19

Applicant: AGILENT TECHNOLOGIES INC

Inventor： YIN HONGFENG ,  BRENNEN REID A ,  LYSTER ERIC ,  SLOCUM ROGER

IPC: G01N30/26 ,  G01N30/60

CPC classification number: G01N30/606 ,  G01N30/6065 ,  G01N30/6086