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公开(公告)号：AT188485T
公开(公告)日：2000-01-15
申请号：AT95917963
申请日：1995-04-26
Applicant: BASF AG
Inventor： AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANITSCHKE LOTHAR , JANSSEN BERND , KARL ULRICH , KLING ANDREAS , MUELLER STEFAN , DE POTZOLLI BERND , RITTER KURT , THYES MARCO , ZIERKE THOMAS
Abstract: PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.
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公开(公告)号：SK76798A3
公开(公告)日：1999-02-11
申请号：SK76798
申请日：1996-12-11
Applicant: BASF AG
Inventor： AMBERG WILHELM , BARLOZZARI TERESA , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , HEGE HANS-GUENTHER , JANSSEN BERND , KLING ANDREAS , LIETZ HELMUT , RITTER KURT , ULLRICH MARTINA , WEYMANN JURGEN , ZIERKE THOMAS
Abstract: Novel peptides of the formula R R N-CHX-CO-A-B-D-E-(G)s-K in which R , R , A, B, D, E, G, K, X, and s have the meanings stated in the description, and the preparation thereof are described. The novel peptides have an antineoplastic effect.
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公开(公告)号：DE59504450D1
公开(公告)日：1999-01-14
申请号：DE59504450
申请日：1995-04-26
Applicant: BASF AG
Inventor： AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANITSCHKE LOTHAR , JANSSEN BERND , KARL ULRICH , KLING ANDREAS , MUELLER STEFAN , DE POTZOLLI BERND , RITTER KURT , THYES MARCO , ZIERKE THOMAS
Abstract: Compounds of the formulawhere R1, R2, R3 and R4 have the meaning stated in the description, and a process for preparing them are described. The compounds are suitable as starting material for synthesizing substances which are active against tumors.
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公开(公告)号：PL327175A1
公开(公告)日：1998-11-23
申请号：PL32717596
申请日：1996-12-11
Applicant: BASF AG
Inventor： AMBERG WILHELM , BARLOZZARI TERESA , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , HEGE HANS-GUENTHER , JANSSEN BERND , KLING ANDREAS , LIETZ HELMUT , RITTER KURT , ULLRICH MARTINA , WEYMANN JUERGEN , ZIERKE THOMAS
Abstract: Novel peptides of the formula R R N-CHX-CO-A-B-D-E-(G)s-K in which R , R , A, B, D, E, G, K, X, and s have the meanings stated in the description, and the preparation thereof are described. The novel peptides have an antineoplastic effect.
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公开(公告)号：CZ139198A3
公开(公告)日：1998-09-16
申请号：CZ139198
申请日：1996-10-30
Applicant: BASF AG
Inventor： KLING ANDREAS , JANSSEN BERND , AMBERG WILHELM , HAUPT ANDREAS , RITTER KURT , BUSCHMANN ERNST , BERNARD HARALD , MULLER STEFAN , ZIERKE THOMAS , BARLOZZARI TERESA , DE ARRUDA MONIKA , ROBINSON SIMON
Abstract: Novel peptides of the formulaA-B-D-E-F-L,wherein A, B, D, E, F, and L have the meanings stated in the specification, and their preparation are disclosed. The novel compounds are suitable for controlling diseases.
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Patent Agency Ranking
公开(公告)号：AT165812T
公开(公告)日：1998-05-15
申请号：AT94924726
申请日：1994-07-08
Applicant: BASF AG
Inventor： KLEIN ULRICH , BUSCHMANN ERNST , KEIL MICHAEL , GOETZ NORBERT , HARREUS ALBRECHT
IPC: C07C239/20
Abstract: PCT No. PCT/EP94/02239 Sec. 371 Date Jan. 11, 1996 Sec. 102(e) Date Jan. 11, 1996 PCT Filed Jul. 8, 1994 PCT Pub. No. WO95/04032 PCT Pub. Date Feb. 9, 1995Preparation of O-substituted hydroxylammonium salts IR1-CHX-O-NH2.HL(I)(L=halogen, hydrogensulfate; X=H, alkyl; R1=unsubst. or subst. phenyl, thienyl, furanyl, pyrrolyl or -CR2=CR3R4; R2, R3, R4=H, halogen or alkyl) by reaction of an acetone oxime O-allyl or -O-benzyl ether II (II) with water and a mineral acid H-L with continuous removal of the acetone formed in this process, by carrying out the hydrolysis batchwise at 0 DEG -50 DEG C. and under a pressure of 10-500 mbar is described. The O-substituted hydroxylammonium salts I are intermediates for plant protection agents and pharmaceuticals.
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公开(公告)号：AU688037B2
公开(公告)日：1998-03-05
申请号：AU2408395
申请日：1995-04-26
Applicant: BASF AG
Inventor： AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANITSCHKE LOTHAR , JANSSEN BERND , KARL ULRICH , KLING ANDREAS , MULLER STEFAN , POTZOLLI BERND DE , RITTER KURT , THYES MARCO , ZIERKE THOMAS
Abstract: PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.
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公开(公告)号：ZA9606372B
公开(公告)日：1998-01-26
申请号：ZA9606372
申请日：1996-07-26
Applicant: BASF AG
Inventor： BUSCHMANN ERNST , ZIERKE THOMAS
IPC: C07C231/02 , C07C237/02 , C07K1/06 , C07K1/08 , C07K7/06 , C07K , C07C
CPC classification number: C07K7/06 , C07C231/02 , C07K1/082 , Y02P20/55
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公开(公告)号：MX9605402A
公开(公告)日：1997-12-31
申请号：MX9605402
申请日：1995-04-26
Applicant: BASF AG
Inventor： AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANITSCHKE LOTHAR , JANSSEN BERND , KARL ULRICH , KLING ANDREAS , MULLER STEFAN
IPC: A61K38/08 , A61K38/00 , A61P35/00 , C07K1/08 , C07K5/10 , C07K5/103 , C07K7/06 , C07K14/52 , C07K07/06
Abstract: Se describe el compuesto Me2Val-MeVal-Pro-Pro-NHBzl.HC1. Se prepara a partir de Z-Val-Val-Meval-Pro-Or1 donde Z y R1 tienen los significados establecidos en la descripcion. El compuesto muestra una actividad antineoplásica.
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公开(公告)号：AT151225T
公开(公告)日：1997-04-15
申请号：AT94905690
申请日：1994-01-24
Applicant: BASF AG
Inventor： BUSCHMANN ERNST , KLEIN ULRICH , NEUMANN ULRICH , RENZ GUENTER
IPC: A01N37/02 , C07C69/145
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