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公开(公告)号：DE3268963D1
公开(公告)日：1986-03-20
申请号：DE3268963
申请日：1982-09-09
Applicant: BASF AG
Inventor： FRANKE ALBRECHT DR , MUELLER JOSEF DR , LIETZ HELMUT , WIERSDORFF WALTER-WIELANT DR , HEGE HANS-GUENTHER DR , MUELLER CLAUS D DR , GRIES JOSEF DR , LENKE DIETER DR , VON PHILIPSBORN GERDA DR , RASCHACK MANFRED DR
IPC: A61K31/13 , A61K31/445 , A61K31/495 , C07C45/62 , C07C45/71 , C07C45/73 , C07C45/74 , C07C49/83 , C07C49/835 , C07C49/84 , C07D211/46 , C07D211/52 , C07D295/08 , C07D295/092 , C07D303/22 , C07D303/24 , C07C93/06 , C07C149/24 , C07C93/14
Abstract: Novel aminopropanol derivatives of 2-hydroxy- beta -phenyl-propiophenones and their physiologically acceptable acid addition compounds, processes for their preparation and therapeutic agents which contain these derivatives and are useful as antiarrhythmic drugs.
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公开(公告)号：DE3374932D1
公开(公告)日：1988-01-28
申请号：DE3374932
申请日：1983-02-16
Applicant: BASF AG
Inventor： MUELLER JOSEF DR , WIERSDORFF WALTER-WIELANT DR , KIRSCHENLOHR WERNER DR , SCHWANTJE GERD DR
IPC: C07C231/00 , C07C67/00 , C07C231/02 , C07C231/12 , C07C233/02 , C07C233/13 , C07C103/375
Abstract: 1. A process for the preparation of an o-acylaminomethylbenzyl halide of the formula (I) see diagramm : EP0087676,P5,F3 where X is halogen and R**1 is an aliphatic or aromatic radical, wherein an o-aminomethylbenzyl alkyl ether of the formula (II) see diagramm : EP0087676,P5,F4 where R**2 is alkyl, is reacted with an acylating agent to give the corresponding acylaminomethylbenzyl alkyl ether, and the latter is reacted with an aqueous hydrohalic acid to give the halide (I).
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Patent Agency Ranking
公开(公告)号：DE3726121A1
公开(公告)日：1989-02-16
申请号：DE3726121
申请日：1987-08-06
Applicant: BASF AG
Inventor： BIRNBACH STEFAN DR , MUELLER JOSEF DR , WULZ KLAUS DR
Abstract: Etherified polyoxyalkylene derivatives of the formula where R1 is hydrogen, C1-C20-alkyl or C3-C5-alkenyl, R2 and R3 independently of one another are each hydrogen, methyl or ethyl, R4 is C1-C4-alkyl and m and n are identical or different and are each greater than or equal to 0, with the proviso that the sum of m and n is from 3 to 300, are prepared by reacting the corresponding hydroxyl-containing polyoxyalkylene derivative with a dialkyl sulfate in the presence of an alkali metal hydroxide by a process in which the reaction is carried out at from 20 DEG to 60 DEG C. in the presence of an aqueous solution of an alkali metal hydroxide, the concentration of alkali metal hydroxide during the entire duration of the reaction being not less than 35% by weight, based on the aqueous phase, and not less than 1 mole of dialkyl sulfate and not less than one mole of alkali metal hydroxide are used per mole equivalent of organic hydroxyl groups.
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公开(公告)号：DE3460280D1
公开(公告)日：1986-08-14
申请号：DE3460280
申请日：1984-10-19
Applicant: BASF AG
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公开(公告)号：DE3341306A1
公开(公告)日：1985-05-23
申请号：DE3341306
申请日：1983-11-15
Applicant: BASF AG
Inventor： MUELLER JOSEF DR , WIERSDORFF WALTER-WIELANT DR , THYES MARCO DR , KIRSCHENLOHR WERNER DR , SCHERER HANS DR
IPC: C07C255/32 , C07C255/33 , C07C255/53 , C07D333/24 , C07C121/68 , C07C121/75
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公开(公告)号：DE3338681A1
公开(公告)日：1985-05-09
申请号：DE3338681
申请日：1983-10-25
Applicant: BASF AG
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公开(公告)号：DE3260043D1
公开(公告)日：1984-03-29
申请号：DE3260043
申请日：1982-02-26
Applicant: BASF AG
Inventor： MUELLER JOSEF DR , WIERSDORFF WALTER-WIELANT DR , KIRSCHENLOHR WERNER DR , SCHWANTJE GERD DR
Abstract: o-Acylphenols and p-acylphenols are prepared by reacting phenol with an acid halide and aluminum chloride, using a halobenzene as the solvent, at from 15 DEG to 55 DEG C. and then at from 55 DEG and 200 DEG C. The compounds obtainable by the process of the invention are valuable starting materials for the preparation of drugs, pesticides and dyes.
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