公开(公告)号：AU760376B2

公开(公告)日：2003-05-15

申请号：AU4455600

申请日：2000-04-12

Applicant: BAXTER INT

Inventor： BILSTAD ARNOLD C ,  BUCHANAN BRADLEY H ,  MARTTILA ALAN W ,  WOODWORTH ARCHIE

IPC: A61L2/24 ,  A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61L2/14 ,  A61L2/20 ,  A61M39/18 ,  B29C65/00 ,  B29C65/02 ,  B29C65/04 ,  B29C65/10 ,  B29C65/48 ,  B67C7/00

Abstract: The connection, assembly, or fill of two or more pre-sterilized components having at least one terminal end each for attachment to another component, and an apparatus for performing such a connection, while maintaining the sterility of the components is disclosed. The resulting connection is made permanent by bonding the contacting components together using either a solvent bonding technique, a radio frequency sealer, a heat sealer, or any other suitable process. The connection is preferably made within an active sterile field. Using a low-voltage electron beam instrument, such as the MIN-EB(TM), a suitable sterile field sphere can be created. The terminal ends of the multiple components remain within the sterile field sphere until the possibility of contamination within the sealed components is significantly reduced to industry acceptable standards.

公开(公告)号：AU607915B2

公开(公告)日：1991-03-21

申请号：AU7430487

申请日：1987-05-07

Applicant: BAXTER INT

Inventor： PATTILLO MARCHA C ,  BACEHOWSKI DAVID C ,  BILSTAD ARNOLD C ,  CULLIS HERBERT M ,  DENNEHEY T MICHAEL ,  YANG JAMES W ,  BROWN WILLIAM C

IPC: C12M3/00 ,  C12M1/00 ,  C12M1/26 ,  C12N5/00 ,  C12N5/10 ,  C12M1/16 ,  C12N5/02 ,  A61B19/00 ,  C12M1/04

Abstract: A system for metering nutrient media to cell culture containers includes a media flow conduit which defines at one end means for substantially aseptic communication with the source of the media. In a preferred embodiment, sterile connectors may be used for essentially sterile conditions. A branch conduit extends from the flow conduit at a location spaced from the ends. The branch conduit communicates with means for receiving a predetermined-volume aliquot of media through the media flow conduit from said one end. The flow conduit also defines a portion downstream from the branch conduit, which communicates with at least one cell culture container, each container being a flexible bag. At least part of the flexible bag is made of a material capable of providing at least 2 times the oxygen diffusion and at least 2 times the carbon dioxide diffusion between the bag interior and exterior, compared with an identically-sized, sealed bag having polyethylene walls 0.013 inch thick.

公开(公告)号：CA2527922C

公开(公告)日：2011-08-16

申请号：CA2527922

申请日：2004-05-20

Applicant: BAXTER INT

Inventor： NEWBROUGH JERRY W ,  SLEPICKA JAMES S ,  BILSTAD ARNOLD C ,  DEFOGGI JOHN MARK ,  BOSCHELLI MARIANNE M ,  JANDRISITS ALICE M ,  WU BIHONG

IPC: A61J1/20 ,  A61J1/00

Abstract: A reconstitution device is disclosed and includes a first container receiver having a first component cannula disposed therein, the first component cannula having a withdrawal port and a first transfer port formed thereon, a second container receiver having a second component cannula disposed thereon, the second component cannula having a vent port and a second transfer port formed thereon, a device body coupling the first container receiver to the second container receiver and having a transfer lumen formed therein, the transfer lumen in fluid communication with the first and second transfer ports, a selectively sealing interface secured to the device body and in fluid communication with the withdrawal port, and a venting member in communication with the vent port through a vent lumen.

公开(公告)号：CA2649673A1

公开(公告)日：2000-10-26

申请号：CA2649673

申请日：2000-04-12

Applicant: BAXTER INT

Inventor： BILSTAD ARNOLD C ,  BUCHANAN BRADLEY H ,  MARTTILA ALAN W ,  WOODWORTH ARCHIE

IPC: A61L2/24 ,  B65B55/02 ,  A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61L2/14 ,  A61L2/20 ,  A61M39/18 ,  B29C65/00 ,  B29C65/02 ,  B29C65/04 ,  B29C65/10 ,  B29C65/48 ,  B67C7/00

Abstract: The connection, assembly, or fill of two or more pre-sterilized components having at least one terminal end each for attachment to another component, and an apparatus for performing such a connection, while maintaining the sterility of the components is disclosed. The resulting connection is made permanent by bonding the contacting components together using either a solvent bonding technique, a radio frequency sealer, a heat sealer, or any other suitable process. The connection is preferably made within an active sterile field. Using a low-voltage electron beam instrument, such as the MIN-EB(TM), a suitable sterile field sphere can be created. The terminal ends of the multiple components remain within the sterile field sphere until the possibility of contamination within the sealed components is significantly reduced to industry acceptable standards.

公开(公告)号：AU3311893A

公开(公告)日：1993-10-07

申请号：AU3311893

申请日：1993-02-17

Applicant: BAXTER INT

Inventor： SCHUMACHER WILLIAM L ,  OILSCHLAGER EDWARD G ,  LILLEGARD THOMAS R ,  BILSTAD ARNOLD C ,  LEWIS ROBERT E ,  SMITH SIDNEY T

IPC: A61J3/00 ,  A61M39/00 ,  B01F13/10 ,  B67D5/56 ,  B65B37/16

Abstract: The present invention provides an improved transfer set for use in an automated compounding device. The transfer set comprises a plurality of fluid conduits, each fluid conduit including a first section and a second section, the first and second sections being coupled together in fluid communication by a coupler. A housing is provided for receiving at least a portion of the fluid conduits and the coupler. The housing defines separate channels for receiving a portion of the second section of each fluid conduit. The channels extend for a sufficient distance so that at least substantially an entire length of the second section that is located in the housing is located in a channel thereby securing the fluid conduits in place in the housing. An improved method for making a transfer set is also provided.

公开(公告)号：AU7430487A

公开(公告)日：1987-12-01

申请号：AU7430487

申请日：1987-05-07

Applicant: BAXTER INT

Inventor： PATTILLO MARCHA C ,  BACEHOWSKI DAVID C ,  BILSTAD ARNOLD C ,  CULLIS HERBERT M ,  DENNEHEY T MICHAEL ,  YANG JAMES W ,  BROWN WILLIAM C

IPC: C12M3/00 ,  C12M1/00 ,  C12M1/26 ,  C12N5/00 ,  C12N5/10 ,  C12M1/16 ,  C12N5/02 ,  A61B19/00

Abstract: A system for metering nutrient media to cell culture containers includes a media flow conduit which defines at one end means for substantially aseptic communication with the source of the media. In a preferred embodiment, sterile connectors may be used for essentially sterile conditions. A branch conduit extends from the flow conduit at a location spaced from the ends. The branch conduit communicates with means for receiving a predetermined-volume aliquot of media through the media flow conduit from said one end. The flow conduit also defines a portion downstream from the branch conduit, which communicates with at least one cell culture container, each container being a flexible bag. At least part of the flexible bag is made of a material capable of providing at least 2 times the oxygen diffusion and at least 2 times the carbon dioxide diffusion between the bag interior and exterior, compared with an identically-sized, sealed bag having polyethylene walls 0.013 inch thick.

公开(公告)号：AU2004244978A1

公开(公告)日：2004-12-16

申请号：AU2004244978

申请日：2004-05-20

Applicant: BAXTER INT

Inventor： BILSTAD ARNOLD C ,  NEWBROUGH JERRY W ,  JANDRISITS ALICE M ,  DEFOGGI JOHN MARK ,  WU BIHONG ,  SLEPICKA JAMES S ,  BOSCHELLI MARIANNE M

IPC: A61J1/20 ,  A61J1/00

Abstract: A reconstitution device is disclosed and includes a first container receiver having a first component cannula disposed therein, the first component cannula having a withdrawal port and a first transfer port formed thereon, a second container receiver having a second component cannula disposed thereon, the second component cannula having a vent port and a second transfer port formed thereon, a device body coupling the first container receiver to the second container receiver and having a transfer lumen formed therein, the transfer lumen in fluid communication with the first and second transfer ports, a selectively sealing interface secured to the device body and in fluid communication with the withdrawal port, and a venting member in communication with the vent port through a vent lumen.

公开(公告)号：NZ514683A

公开(公告)日：2003-10-31

申请号：NZ51468300

申请日：2000-04-12

Applicant: BAXTER INT

Inventor： BILSTAD ARNOLD C ,  MARTTILA ALAN W ,  WOODWORTH ARCHIE ,  UCHANAN BRADLEY H

IPC: A61L2/24 ,  A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61L2/14 ,  A61L2/20 ,  A61M39/18 ,  B29C65/00 ,  B29C65/02 ,  B29C65/04 ,  B29C65/10 ,  B29C65/48 ,  B67C7/00

Abstract: The connection, assembly, or fill of two or more pre- sterilized components having at least one terminal end each for attachment to another component, and an apparatus for performing such a connection, while maintaining the sterility of the components is disclosed. The resulting connection is made permanent by bonding the contacting components together using either a solvent bonding technique, a radio frequency sealer, a heat sealer, or any other suitable process. The connection is preferably made within an active sterile field. Using a low-voltage electron beam instrument, such as the MIN-EB(TM), a suitable sterile field sphere can be created. The terminal ends of the multiple components remain within the sterile field sphere until the possibility of contamination within the sealed components is significantly reduced to industry acceptable standards.

公开(公告)号：BR0009908A

公开(公告)日：2002-01-08

申请号：BR0009908

申请日：2000-04-12

Applicant: BAXTER INT

Inventor： BILSTAD ARNOLD C ,  BUCHANAN BRADLEY H ,  MARTTILA ALAN W ,  WOODWORTH ARCHIE

IPC: A61L2/24 ,  A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61L2/14 ,  A61L2/20 ,  A61M39/18 ,  B29C65/00 ,  B29C65/02 ,  B29C65/04 ,  B29C65/10 ,  B29C65/48 ,  B67C7/00

Abstract: The connection, assembly, or fill of two or more pre-sterilized components having at least one terminal end each for attachment to another component, and an apparatus for performing such a connection, while maintaining the sterility of the components is disclosed. The resulting connection is made permanent by bonding the contacting components together using either a solvent bonding technique, a radio frequency sealer, a heat sealer, or any other suitable process. The connection is preferably made within an active sterile field. Using a low-voltage electron beam instrument, such as the MIN-EB(TM), a suitable sterile field sphere can be created. The terminal ends of the multiple components remain within the sterile field sphere until the possibility of contamination within the sealed components is significantly reduced to industry acceptable standards.

公开(公告)号：AU4455600A

公开(公告)日：2000-11-02

申请号：AU4455600

申请日：2000-04-12

Applicant: BAXTER INT

Inventor： BILSTAD ARNOLD C ,  BUCHANAN BRADLEY H ,  MARTTILA ALAN W ,  WOODWORTH ARCHIE

IPC: A61L2/24 ,  A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61L2/14 ,  A61L2/20 ,  A61M39/18 ,  B29C65/00 ,  B29C65/02 ,  B29C65/04 ,  B29C65/10 ,  B29C65/48 ,  B67C7/00

Abstract: The connection, assembly, or fill of two or more pre-sterilized components having at least one terminal end each for attachment to another component, and an apparatus for performing such a connection, while maintaining the sterility of the components is disclosed. The resulting connection is made permanent by bonding the contacting components together using either a solvent bonding technique, a radio frequency sealer, a heat sealer, or any other suitable process. The connection is preferably made within an active sterile field. Using a low-voltage electron beam instrument, such as the MIN-EB(TM), a suitable sterile field sphere can be created. The terminal ends of the multiple components remain within the sterile field sphere until the possibility of contamination within the sealed components is significantly reduced to industry acceptable standards.