-
公开(公告)号：DE60041658D1
公开(公告)日：2009-04-09
申请号：DE60041658
申请日：2000-12-08
Applicant: FUSO PHARMACEUTICAL IND
Inventor： ARAKI HIROMASA , KAWABATA ATSUFUMI , TANAKA SHUICHI , KAWAI KENZO , NISHIMURA SACHIYO , NISHIKAWA HIROYUKI
IPC: A61K45/00 , G02C7/04 , A61F9/00 , A61K9/06 , A61K9/08 , A61K9/10 , A61K38/00 , A61K38/08 , A61K38/17 , A61K38/48 , A61K38/55 , A61K45/06 , A61L27/22 , A61P27/02 , A61P43/00 , C07K7/06 , C12N9/76 , C12N9/99 , G02B1/04 , G02C13/00
Abstract: A composition for promoting lacrimal secretion, comprising a protease-activated receptor (PAR)-2 agonist, is new. Independent claims are also included for the following: (1) drug delivery systems comprising the above composition; and (2) contact lenses coated in and/or containing the above composition. ACTIVITY : Ophthalmological. In tests Ser-Leu-ILe-Gly-Leu-NH 2administered to Wistar rats at 5 Micromol/kg by tail vein injection significantly (p is less than 0.01) increased lacrimal secretion. MECHANISM OF ACTION : Protease-agonist.
-
公开(公告)号：AU777262B2
公开(公告)日：2004-10-07
申请号：AU1734201
申请日：2000-12-08
Applicant: FUSO PHARMACEUTICAL IND
Inventor： ARAKI HIROMASA , KAWABATA ATSUFUMI , TANAKA SHUICHI , KAWAI KENZO , NISHIMURA SACHIYO , NISHIKAWA HIROYUKI
IPC: G02C7/04 , A61F9/00 , A61K9/06 , A61K9/08 , A61K9/10 , A61K38/00 , A61K38/17 , A61K38/48 , A61K45/00 , A61K45/06 , A61L27/22 , A61P27/02 , A61P43/00 , C07K7/06 , C12N9/76 , C12N9/99 , G02B1/04 , G02C13/00 , A61K38/08
Abstract: A composition for promoting lacrimal secretion, comprising a protease-activated receptor (PAR)-2 agonist, is new. Independent claims are also included for the following: (1) drug delivery systems comprising the above composition; and (2) contact lenses coated in and/or containing the above composition. ACTIVITY : Ophthalmological. In tests Ser-Leu-ILe-Gly-Leu-NH 2administered to Wistar rats at 5 Micromol/kg by tail vein injection significantly (p is less than 0.01) increased lacrimal secretion. MECHANISM OF ACTION : Protease-agonist.
-
公开(公告)号：CA2912522C
公开(公告)日：2021-05-11
申请号：CA2912522
申请日：2014-05-16
Applicant: UNIV KINKI , FUSO PHARMACEUTICAL IND
Inventor： KAWABATA ATSUFUMI , MATSUDA HIDEAKI , SEKIGUCHI FUMIKO , MURATA KAZUYA , NISHIKAWA HIROYUKI
IPC: A61K31/352 , A61P3/14 , A61P25/04
Abstract: ABSTRACT Disclosed is a T-type calcium channel inhibitor which is a compound represented by formula (1) as shown below and defined herein, a pharmaceutically acceptable salt of this compound or a solvate of this compound. Also disclosed is a pharmaceutical product containing this T-type calcium channel inhibitor; and a therapeutic agent or prophylactic agent for diseases, the effective action of which is a T-type calcium channel inhibitory action. R1 R6 R2 R5 R3 0 ( 1) CA 2912522 2019-04-25
-
14.发明专利
公开(公告)号：CA2726161A1
公开(公告)日：2009-12-23
申请号：CA2726161
申请日：2009-06-15
Applicant: UNIV KINKI , FUSO PHARMACEUTICAL IND
Inventor： KAWABATA ATSUFUMI , NISHIKAWA HIROYUKI , KAWAI KENZO
Abstract: Disclosed is a composition for promoting the secretion of a tear, which can be used safely and effectively in tear secretion promotion therapies rather than conventional therapies for supplementing a tear component, and can exhibit its effect for a long period. Specifically disclosed are: a composition for promoting the secretion of a tear, which is characterized by comprising a peptide derivative represented by formula (I); and a contact lens retaining and/or containing the composition.
-
公开(公告)号：CA2396542A1
公开(公告)日：2001-07-05
申请号：CA2396542
申请日：2000-12-08
Applicant: FUSO PHARMACEUTICAL IND
Inventor： KAWAI KENZO , NISHIMURA SACHIYO , TANAKA SHUICHI , NISHIKAWA HIROYUKI , KAWABATA ATSUFUMI , ARAKI HIROMASA
IPC: G02C7/04 , A61F9/00 , A61K9/06 , A61K9/08 , A61K9/10 , A61K38/00 , A61K38/17 , A61K38/48 , A61K45/00 , A61K45/06 , A61L27/22 , A61P27/02 , A61P43/00 , C07K7/06 , C12N9/76 , C12N9/99 , G02B1/04 , G02C13/00 , A61K38/08
Abstract: A composition promoting lacrimal secretion which can be safely and efficaciously used in the treatment of promoting lacrimal secretion differen t from the conventional treatment of supplying lacrimal components. This composition is characterized by containing a component activating PAR-2. Als o, contact lenses carrying and/or containing this composition are provided.
-
Patent Agency Ranking
公开(公告)号：CA2396542C
公开(公告)日：2011-04-12
申请号：CA2396542
申请日：2000-12-08
Applicant: FUSO PHARMACEUTICAL IND
Inventor： ARAKI HIROMASA , KAWABATA ATSUFUMI , TANAKA SHUICHI , KAWAI KENZO , NISHIMURA SACHIYO , NISHIKAWA HIROYUKI
IPC: A61K38/55 , G02C7/04 , A61F9/00 , A61K9/06 , A61K9/08 , A61K9/10 , A61K38/00 , A61K38/08 , A61K38/17 , A61K38/48 , A61K45/00 , A61K45/06 , A61L12/08 , A61L27/22 , A61P27/02 , A61P43/00 , C07K7/06 , C12N9/76 , C12N9/99 , G02B1/04 , G02C13/00
Abstract: T he present invention is directed to a composition for promoting lacrimal secretion which can be used safely and effectively in lacrimal secretion promoting therapy, not in conventional supplemental therapy of lacrimal fluid components. The composition comprises a component which activates PAR-2. Also, a contact lens which retains and/or contains said composition for promoting lacrimal secretion is provided.
-
公开(公告)号：CA2400650C
公开(公告)日：2010-10-19
申请号：CA2400650
申请日：2001-02-20
Applicant: FUSO PHARMACEUTICAL IND
Inventor： ARAKI HIROMASA , KAWABATA ATSUFUMI , KURODA RYOTARO , KAKEHI KAZUAKI , TANAKA SHUICHI , KAWAI KENZO , NISHIMURA SACHIYO , NISHIKAWA HIROYUKI
IPC: A61K9/00 , A61K38/55 , A61K38/00 , A61K38/08 , A61K38/17 , A61K38/46 , A61K38/48 , A61K45/00 , A61K45/06 , A61P1/00 , A61P1/04 , A61P1/12
Abstract: The present invention provides a composition for safely and effectively preventing and treating digestive organs diseases, particularly, gastric ulcer, duodenal ulcer, gastritis, diarrhea, enteritis and the like. There is also provided a composition having a novel mechanism of action in order to solve problems that were difficult to solve by the side effects of previously known mechanisms of action. More particularly, there is provided a pharmaceutical composition containing an ingredient which activates PAR-2 as an essential ingredient, which is useful for inhibiting gastric acid secretion, promoting digestive tract mucus secretion, protecting digestive tract mucosa, repairing tissue of digestive organs, and preventing and treating digestive organs diseases.
-
公开(公告)号：AU2009261285A1
公开(公告)日：2009-12-23
申请号：AU2009261285
申请日：2009-06-15
Applicant: UNIV KINKI , FUSO PHARMACEUTICAL IND
Inventor： KAWAI KENZO , KAWABATA ATSUFUMI , NISHIKAWA HIROYUKI
Abstract: A composition for promoting lacrimal secretion which can be used safely and effectively in the lacrimal secretion promoting therapy, not in the conventional supplemental therapy of lacrimal fluid components is provided. The composition for promoting lacrimal secretion comprising a peptide derivative represented by the formula (I): and a contact lens which retains and/or contains the composition are provided.
-
公开(公告)号：AU3234501A
公开(公告)日：2001-09-03
申请号：AU3234501
申请日：2001-02-20
Applicant: FUSO PHARMACEUTICAL IND
Inventor： ARAKI HIROMASA , KAWABATA ATSUFUMI , KURODA RYOTARO , KAKEHI KAZUAKI , TANAKA SHUICHI , KAWAI KENZO , NISHIMURA SACHIYO , NISHIKAWA HIROYUKI
IPC: A61K9/00 , A61K38/00 , A61K38/08 , A61K38/17 , A61K38/46 , A61K38/55 , A61K45/00 , A61K45/06 , A61P1/04 , A61P1/12 , A61K38/48
Abstract: The present invention provides a composition for safely and effectively preventing and treating digestive organs diseases, particularly, gastric ulcer, duodenal ulcer, gastritis, diarrhea, enteritis and the like. There is also provided a composition having a novel mechanism of action in order to solve the problems which was difficult to be solved by the side effect previously known mechanisms of action. More particularly, there is provided a pharmaceutical composition containing an ingredient which activates PAR-2 as an essential ingredient, which is useful for inhibiting gastric acid secretion, promoting digestive tract mucus secretion, protecting digestive tract mucosa, repairing tissue of digestive organs, and preventing and treating digestive organs diseases.
-
公开(公告)号：CA2400650A1
公开(公告)日：2001-08-30
申请号：CA2400650
申请日：2001-02-20
Applicant: FUSO PHARMACEUTICAL IND
Inventor： NISHIKAWA HIROYUKI , NISHIMURA SACHIYO , TANAKA SHUICHI , KAWAI KENZO , KURODA RYOTARO , KAKEHI KAZUAKI , KAWABATA ATSUFUMI , ARAKI HIROMASA
IPC: A61K9/00 , A61K38/00 , A61K38/08 , A61K38/17 , A61K38/46 , A61K38/55 , A61K45/00 , A61K45/06 , A61P1/04 , A61P1/12 , A61K38/48
Abstract: Compositions for safely and effectively preventing and treating digestive diseases, in particular, gastric ulcer, duodenal ulcer, gastritis, diarrhea, enteritis, etc. Compositions having a novel function mechanism for solving t he problem of side effects which can be hardly overcome by the publicly known function mechanisms. More particularly speaking, medicinal compositions essentially containing a component activating PAR-2 which are useful in controlling gastric hydrochloric acid secretion, promoting digestive mucous secretion, protecting gastric mucosae, repairing gastric tissues and preventing and treating gastric diseases.
-
-
-
-
-
-
-
-
-
Search Results
20
records
(took 0.027 seconds)
