Abstract:
The present invention provides a composition for safely and effectively preventing and treating digestive organs diseases, particularly, gastric ulcer, duodenal ulcer, gastritis, diarrhea, enteritis and the like. There is also provided a composition having a novel mechanism of action in order to solve the problems which was difficult to be solved by the side effect previously known mechanisms of action. More particularly, there is provided a pharmaceutical composition containing an ingredient which activates PAR-2 as an essential ingredient, which is useful for inhibiting gastric acid secretion, promoting digestive tract mucus secretion, protecting digestive tract mucosa, repairing tissue of digestive organs, and preventing and treating digestive organs diseases.
Abstract:
A composition promoting lacrimal secretion which can be safely and efficaciously used in the treatment of promoting lacrimal secretion different from the conventional treatment of supplying lacrimal components. This composition is characterized by containing a component activating PAR-2. Also, contact lenses carrying and/or containing this composition are provided.
Abstract:
A composition promoting lacrimal secretion which can be safely and efficaciously used in the treatment of promoting lacrimal secretion differen t from the conventional treatment of supplying lacrimal components. This composition is characterized by containing a component activating PAR-2. Als o, contact lenses carrying and/or containing this composition are provided.
Abstract:
The present invention provides a composition for safely and effectively preventing and treating digestive organs diseases, particularly, gastric ulcer, duodenal ulcer, gastritis, diarrhea, enteritis and the like. There is also provided a composition having a novel mechanism of action in order to solve the problems which was difficult to be solved by the side effect previously known mechanisms of action. More particularly, there is provided a pharmaceutical composition containing an ingredient which activates PAR-2 as an essential ingredient, which is useful for inhibiting gastric acid secretion, promoting digestive tract mucus secretion, protecting digestive tract mucosa, repairing tissue of digestive organs, and preventing and treating digestive organs diseases.
Abstract:
A composition for promoting lacrimal secretion, comprising a protease-activated receptor (PAR)-2 agonist, is new. Independent claims are also included for the following: (1) drug delivery systems comprising the above composition; and (2) contact lenses coated in and/or containing the above composition. ACTIVITY : Ophthalmological. In tests Ser-Leu-ILe-Gly-Leu-NH 2administered to Wistar rats at 5 Micromol/kg by tail vein injection significantly (p is less than 0.01) increased lacrimal secretion. MECHANISM OF ACTION : Protease-agonist.
Abstract:
A composition for promoting lacrimal secretion, comprising a protease-activated receptor (PAR)-2 agonist, is new. Independent claims are also included for the following: (1) drug delivery systems comprising the above composition; and (2) contact lenses coated in and/or containing the above composition. ACTIVITY : Ophthalmological. In tests Ser-Leu-ILe-Gly-Leu-NH 2administered to Wistar rats at 5 Micromol/kg by tail vein injection significantly (p is less than 0.01) increased lacrimal secretion. MECHANISM OF ACTION : Protease-agonist.
Abstract:
T he present invention is directed to a composition for promoting lacrimal secretion which can be used safely and effectively in lacrimal secretion promoting therapy, not in conventional supplemental therapy of lacrimal fluid components. The composition comprises a component which activates PAR-2. Also, a contact lens which retains and/or contains said composition for promoting lacrimal secretion is provided.
Abstract:
The present invention provides a composition for safely and effectively preventing and treating digestive organs diseases, particularly, gastric ulcer, duodenal ulcer, gastritis, diarrhea, enteritis and the like. There is also provided a composition having a novel mechanism of action in order to solve problems that were difficult to solve by the side effects of previously known mechanisms of action. More particularly, there is provided a pharmaceutical composition containing an ingredient which activates PAR-2 as an essential ingredient, which is useful for inhibiting gastric acid secretion, promoting digestive tract mucus secretion, protecting digestive tract mucosa, repairing tissue of digestive organs, and preventing and treating digestive organs diseases.
Abstract:
The present invention provides a composition for safely and effectively preventing and treating digestive organs diseases, particularly, gastric ulcer, duodenal ulcer, gastritis, diarrhea, enteritis and the like. There is also provided a composition having a novel mechanism of action in order to solve the problems which was difficult to be solved by the side effect previously known mechanisms of action. More particularly, there is provided a pharmaceutical composition containing an ingredient which activates PAR-2 as an essential ingredient, which is useful for inhibiting gastric acid secretion, promoting digestive tract mucus secretion, protecting digestive tract mucosa, repairing tissue of digestive organs, and preventing and treating digestive organs diseases.