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    T-TYPE CALCIUM CHANNEL INHIBITOR
    2.
    发明公开
    T-TYPE CALCIUM CHANNEL INHIBITOR 审中-公开
    T-型钙通道抑制剂

    公开(公告)号：EP3000465A4

    公开(公告)日：2016-12-07

    申请号：EP14801611

    申请日：2014-05-16

    Applicant: UNIV KINKI ,  FUSO PHARMACEUTICAL IND

    Inventor： KAWABATA ATSUFUMI ,  MATSUDA HIDEAKI ,  SEKIGUCHI FUMIKO ,  MURATA KAZUYA ,  NISHIKAWA HIROYUKI

    IPC: A61K31/352 ,  A61P3/14 ,  A61P25/04 ,  C07D311/32

    CPC classification number: C07D311/32 ,  A61K31/352

    Abstract: The present invention provides a T-type calcium channel inhibitor which is a compound represented by formula (1), a pharmaceutically acceptable salt of this compound or a solvate of this compound. The present invention also provides: this T-type calcium channel inhibitor; a pharmaceutical product containing this T-type calcium channel inhibitor; and a therapeutic agent or prophylactic agent for diseases, the effective action of which is a T-type calcium channel inhibitory action. (In formula (1), each of R 1 and R 2 independently represents H, -OH or -OR 11 , wherein R 11 represents a C 1-3 alkyl group; each of R 3 and R 4 independently represents H, -OH or -OR 12 , wherein R 12 represents a C 1-3 alkyl group; and each of R 5 and R 6 independently represents H, a halogen atom, a C 1-10 alkyl group, a C 2-6 alkenyl group, a C 2-6 alkynyl group, a phenyl group (which may be substituted by a C 1-6 alkoxy group or a halogen atom), a -C 1-3 alkyl-phenyl group (which may be substituted by a C 1-6 alkyloxy group or a halogen atom) or a C 10-50 prenyl group.)

    T-TYPE CALCIUM CHANNEL INHIBITOR
    5.
    发明专利
    T-TYPE CALCIUM CHANNEL INHIBITOR 未知

    公开(公告)号：CA2912522A1

    公开(公告)日：2014-11-27

    申请号：CA2912522

    申请日：2014-05-16

    Applicant: UNIV KINKI ,  FUSO PHARMACEUTICAL IND

    Inventor： KAWABATA ATSUFUMI ,  MATSUDA HIDEAKI ,  SEKIGUCHI FUMIKO ,  MURATA KAZUYA ,  NISHIKAWA HIROYUKI

    IPC: A61K31/352 ,  A61P3/14 ,  A61P25/04

    Abstract: The present invention provides a T-type calcium channel inhibitor which is a compound represented by formula (1), a pharmaceutically acceptable salt of this compound or a solvate of this compound. The present invention also provides: this T-type calcium channel inhibitor; a pharmaceutical product containing this T-type calcium channel inhibitor; and a therapeutic agent or prophylactic agent for diseases, the effective action of which is a T-type calcium channel inhibitory action. (In formula (1), each of R1 and R2 independently represents H, -OH or -OR11, wherein R11 represents a C1-3 alkyl group; each of R3 and R4 independently represents H, -OH or -OR12, wherein R12 represents a C1-3 alkyl group; and each of R5 and R6 independently represents H, a halogen atom, a C1-10 alkyl group, a C2-6 alkenyl group, a C2-6 alkynyl group, a phenyl group (which may be substituted by a C1-6 alkoxy group or a halogen atom), a -C1-3 alkyl-phenyl group (which may be substituted by a C1-6 alkyloxy group or a halogen atom) or a C10-50 prenyl group.)

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