公开(公告)号：DE69909897D1

公开(公告)日：2003-09-04

申请号：DE69909897

申请日：1999-05-14

Applicant: IDEXX LAB INC

Inventor： GROAT RANDALL G ,  MERMER BRION ,  O'CONNOR THOMAS P

IPC: C07K7/08 ,  C07K14/155 ,  G01N33/569

Abstract: We disclose methods for determining whether a feline is infected with feline immunodeficiency virus ("FIV"). The methods involve the use of an antibody-binding composition that includes two enhanced polypeptides, one containing an immunogenic fragment of the FIV gag precursor p55 and the other containing an immunogenic fragment of the FIV env precursor gp130. Also disclosed are devices for practising these methods.

公开(公告)号：AU6401800A

公开(公告)日：2001-03-05

申请号：AU6401800

申请日：2000-08-09

Applicant: IDEXX LAB INC

Inventor： GUO HONGLIANG ,  LAWTON ROBERT ,  MERMER BRION ,  AIYAPPA ASHOK P

IPC: A61K38/00 ,  A61K39/00 ,  C07K14/54 ,  C07K16/24 ,  C12N15/24 ,  A61K38/20 ,  A61K39/395 ,  C12N5/10 ,  C12N15/11 ,  G01N33/68

公开(公告)号：DE69922873D1

公开(公告)日：2005-02-03

申请号：DE69922873

申请日：1999-04-09

Applicant: IDEXX LAB INC

Inventor： LAWTON ROBERT ,  MERMER BRION ,  FRANCOEUR GREG

IPC: C07K16/42 ,  C07K7/06 ,  A61K39/395 ,  C07K7/08 ,  C07K16/06 ,  C07K16/28

公开(公告)号：AU754309B2

公开(公告)日：2002-11-14

申请号：AU2806799

申请日：1999-05-11

Applicant: IDEXX LAB INC

Inventor： GROAT RANDALL G ,  O'CONNOR THOMAS P ,  MERMER BRION

IPC: C07K7/08 ,  C07K14/155 ,  G01N33/569 ,  G01N33/571

Abstract: We disclose methods for determining whether a feline is infected with feline immunodeficiency virus ("FIV"). The methods involve the use of an antibody-binding composition that includes two enhanced polypeptides, one containing an immunogenic fragment of the FIV gag precursor p55 and the other containing an immunogenic fragment of the FIV env precursor gp130. Also disclosed are devices for practising these methods.

公开(公告)号：AU2806799A

公开(公告)日：1999-11-25

申请号：AU2806799

申请日：1999-05-11

Applicant: IDEXX LAB INC

Inventor： GROAT RANDALL G ,  MERMER BRION ,  O'CONNOR THOMAS P

IPC: C07K7/08 ,  C07K14/155 ,  G01N33/569 ,  G01N33/571

Abstract: We disclose methods for determining whether a feline is infected with feline immunodeficiency virus ("FIV"). The methods involve the use of an antibody-binding composition that includes two enhanced polypeptides, one containing an immunogenic fragment of the FIV gag precursor p55 and the other containing an immunogenic fragment of the FIV env precursor gp130. Also disclosed are devices for practising these methods.

公开(公告)号：CA2271449A1

公开(公告)日：1999-11-15

申请号：CA2271449

申请日：1999-05-14

Applicant: IDEXX LAB INC

Inventor： MERMER BRION ,  O'CONNOR THOMAS P ,  GROAT RANDALL G

IPC: C07K7/08 ,  C07K14/155 ,  G01N33/569 ,  C12Q1/70 ,  G01N33/577

Abstract: Methods for determining whether a feline is infected with feline immunodeficiency virus ("FIV"). The methods involve the use of an antibody-binding composition that includes two enhanced polypeptides, one containing an immunogenic fragment of the FIV gag precursor p55 and the other containing an immunogenic fragment of the FIV env precursor gp130. Also featured a.re devices for practicing these methods.

公开(公告)号：AU2125697A

公开(公告)日：1997-09-02

申请号：AU2125697

申请日：1997-02-14

Applicant: IDEXX LAB INC

Inventor： MERMER BRION ,  HARRIS RACHEL A ,  SIEFRING ANN E

IPC: A61K38/00 ,  C07K16/00 ,  C12N15/13 ,  A61K39/395 ,  C12N5/10 ,  C12N15/11

公开(公告)号：CA2329148C

公开(公告)日：2012-05-29

申请号：CA2329148

申请日：2000-03-30

Applicant: IDEXX LAB INC

Inventor： LAWTON ROBERT ,  MERMER BRION ,  FRANCOEUR GREG

IPC: C07K16/42 ,  C12N15/09 ,  A61K38/00 ,  A61K39/395 ,  A61K39/44 ,  A61P37/08 ,  C07K14/47 ,  C12P21/08

Abstract: Disclosed are binding proteins that specifically bind to an isolated and purified peptide comprising a leucine positioned two peptide bonds away from a tyrosine-arginine pair. Other binding proteins of the invention include those that specifically bind to an isolated and purified peptide with the sequence cysteine-blank-blank-proline-histidine-blank-blank-blank-cysteine (SEQ ID NO:6) or cysteine-blank-proline-histidine-blank-proline-blank-blank-cysteine (SEQ ID NO:9).

公开(公告)号：DE60127237D1

公开(公告)日：2007-04-26

申请号：DE60127237

申请日：2001-01-30

Applicant: IDEXX LAB INC

Inventor： LAWTON ROBERT L ,  AIYAPPA ASHOK P ,  LIU WENDY W ,  MERMER BRION ,  GUO HONGLIANG ,  KRAH EUGENE R

IPC: C07K16/42 ,  C12N15/09 ,  A61K9/08 ,  A61K39/395 ,  A61P37/08 ,  A61P43/00 ,  C12P21/08

Abstract: The present invention provides methods and compositions for decreasing IgE levels in dogs. The methods and compositions are useful for treating allergic symptoms in dogs. The invention may comprise chimeric canine anti-IgE monoclonal antibody compositions and methods for using the compositions in the treatment of allergy. In preferred embodiments, the compositions of the present invention may act by binding soluble IgE in plasma, or by inhibiting IgE from binding to receptors on mast cells, B cells, and basophils.

公开(公告)号：DE69922873T2

公开(公告)日：2005-12-29

申请号：DE69922873

申请日：1999-04-09

Applicant: IDEXX LAB INC

Inventor： LAWTON ROBERT ,  MERMER BRION ,  FRANCOEUR GREG

IPC: C07K16/42 ,  C07K7/06 ,  A61K39/395 ,  C07K7/08 ,  C07K16/06 ,  C07K16/28