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公开(公告)号:JPH02270810A
公开(公告)日:1990-11-05
申请号:JP9420089
申请日:1989-04-13
Applicant: KAO CORP
Inventor: OTOMO TAKESHI , SAITO KAZUMI , MINEMATSU YOSHIHIRO
Abstract: PURPOSE:To obtain an emulsion cosmetic having high durative humectant effect, softening effect, lowered greasiness and tackiness, and good feeling by using a novel liquid oil agent of a specific diacylglycerol, a surfactant and water. CONSTITUTION:(A) A liquid oil which is substantially composed of a novel diacylglycerol of the formula (one of R1 through R3 is a residue of saturated 11-17C straight-chain fatty acid; another, saturated 10-18C branched-chain fatty acid and the rest, H), as an oil is emulsified using (B) a surface active agent in (C) water, to give the subject oil cosmetic which shows the effects stated above, because component (A) has adequate effects of blocking and softening skins, mucous membranes and hairs and shows lowered irritation, despite high permeation through keratin, and high stability. In the composition, the amount of (A) is preferably 0.1 to 80wt.%, particularly 1 to 20wt.%; (B) is 0.05 to 10wt.%, particularly 0.1 to 5wt.%; and (C) is the remainder, namely 10 to 99wt.%.
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公开(公告)号:JPH01126535A
公开(公告)日:1989-05-18
申请号:JP28578087
申请日:1987-11-12
Applicant: KAO CORP
Inventor: HONMA YASUHIRO , MIYAZAKI NOBUO , MISUMI HISASHI , SUDA TOSHIYASU , AKASAKI SHUICHI , MINEMATSU YOSHIHIRO , KAWAI MICHIO
Abstract: PURPOSE:To enable accurate diagnosis of skin, by altering the connection of a measuring electrode to measure content of moisture existing in a surface layer or at a depth of a corneous layer. CONSTITUTION:A sine wave signal oscillated with a sine wave oscillator 1 has the waveform thereof shaped and the amplitude thereof stabilized with a buffer circuit 2' to be applied to a measuring electrode 3'. An output of the circuit 2' is applied between an electrode 3'a and the ground. A voltage to be applied to the electrode 3' is set at a weak voltage. Here, when the electrode 3' is put on skin to be inspected, a potential difference between an intermediate electrode 3'b and a center electrode 3'c varies depending on a moisture content at a depth of a corneous layer and a detection voltage thereof is amplified 5'. As a result, an output current of the circuit 2' flows between the electrode 3'a and the electrode 3'c and the potential difference appears at an output of a circuit 5' to remove a short cycle of noise with a filter circuit 6. Then, an AC voltage thus filtered 6 is rectified and detected 7 and thus, a DC voltage corresponding to a peak value is inversely proportional to an absolute value of impedance at a depth of the corneous layer.
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公开(公告)号:JPS63297309A
公开(公告)日:1988-12-05
申请号:JP13205487
申请日:1987-05-28
Applicant: KAO CORP
Inventor: KAWAMATA AKIRA , MINEMATSU YOSHIHIRO , AKASAKI SHUICHI , ZAMA MITSUKO , IMOKAWA GENJI , TAKAISHI NAOTAKE
IPC: A61K8/30 , A61K8/00 , A61K8/42 , A61K8/55 , A61K8/58 , A61K8/68 , A61K33/42 , A61P17/00 , A61Q5/00 , A61Q19/00 , C07F9/10 , C07H15/04
Abstract: PURPOSE:To obtain a skin drug for external use, containing a specific lipid derivative and surfactant and capable of enhancing water holding power of a keratinous layer and improving roughening of the skin. CONSTITUTION:A medicinal skin drug for external use or cosmetic (e.g. cream, milky lotion, toilet water, lipstick, foundation or hairdressing) containing a lipid derivative expressed by formula I [R1 is 10-26C alkyl; R2 is 9-25C alkyl; X and Y are H or phosphoric acid ester group expressed by formula II (R3-R5 are H, 1-6C alkyl or aralkyl), provided that X and Y are not H at the same time]. The amount of the blended compound expressed by formula I is preferably 0.1-20wt.% based on the total composition in the case of an emulsion type agent and 5-25wt.% in the case of an oily agent containing a liquid hydrocarbon as a base. The surfactant has action on enhancement of effects and a glyceryl ether expressed by formula III [R6 is 8-24C alkyl, especially preferably a group expressed by formula IV (p is 4-10; q is 5-11)] is preferred. The amount thereof blended is 0.1-5wt.% based on the total composition.
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公开(公告)号:JPS63227513A
公开(公告)日:1988-09-21
申请号:JP6071887
申请日:1987-03-16
Applicant: KAO CORP
Inventor: YANO SHINJI , KAWAMATA AKIRA , MINEMATSU YOSHIHIRO , AKASAKI SHUICHI , ZAMA MITSUKO , IMOKAWA GENJI , TAKAISHI NAOTAKE
IPC: A61K8/30 , A61K8/00 , A61K8/42 , A61K8/68 , A61K31/22 , A61P17/00 , A61Q5/00 , A61Q19/00 , C07C67/00 , C07C231/00 , C07C233/18 , C07C233/20 , C07H15/04
Abstract: PURPOSE:To obtain a dermatic drug for external application effective in increasing water-retainability of corneum and ameliorating chapped skin, by using a specific amide derivative as essential component. CONSTITUTION:The objective agent contains a compound of formula I [R is 10-26C hydrocarbon group; R is 9-25C hydrocarbon group; m is integer of >=0; n is integer of >=1 (excluding the case of m=0 and n=1) [e.g. N-(2- hydroxy-3-hexadecyloxypropyl)-N-2-hydroxyethoxyethylhe-xadecanamide]. Preferably, the amount of the compound is 0.001-50wt.%, especially 0.1-20% for emulsion-type external drug and 1-50%, especially 5-25% for oil-based external drug for skin. It is preferable to compound 0.01-20% surfactant. The compound of formula I can be produced by acylating a compound of formula II with a fatty acid chloride of formula R COCl and selectively hydrolyzing the ester group of the resultant compound of formula III.
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公开(公告)号:JPH0672851A
公开(公告)日:1994-03-15
申请号:JP15734293
申请日:1993-06-28
Applicant: KAO CORP
Inventor: TAKANABE EISHIN , TOKIMITSU ICHIROU , MINEMATSU YOSHIHIRO
IPC: A61K8/30 , A61K8/00 , A61K8/68 , A61K8/72 , A61K8/89 , A61P17/16 , A61Q19/00 , C08L83/04 , C08L83/08 , A61K7/48 , A61K7/00
Abstract: PURPOSE:To obtain skin cosmetics having excellent moisture retention, no irritation and no greasy feeling, thus giving good application feeling with high durability, by using an amphiphilic lipid and a specific organopolysiloxane. CONSTITUTION:The objective cosmetics contain 1 to 40wt.% of an amphiphilic lipid such as phospholipid and 0.01 to 40wt.% of a compound of formula I and formula II (R , R are 1 to 4C alkyl; R is 1 to 40C alkyl, alkenyl, fluoroalkyl; R is 7 to 40C alkyl, alkenyl, fluoroalkyl; l is 2 or more; m is 3 or more and l+m is 5 to 6,000). In addition, the additives used in usual cosmetics such as salts, oil, emulsion, powder, ultraviolet scattering agent, pH adjuster, thickener, pigments, preservative, antioxidant, fungicidal or water-soluble solvents are suitably used to produce emulsion, dispersion, double-layered or solubilized preparations. Since the humectant is not flown off by sweat or water, the preparation can stay on the application site to sustain the moisture retention effect for hours.
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公开(公告)号:JPH0672824A
公开(公告)日:1994-03-15
申请号:JP15734193
申请日:1993-06-28
Applicant: KAO CORP
Inventor: TAKANABE EISHIN , TOKIMITSU ICHIROU , MINEMATSU YOSHIHIRO
IPC: A61K8/30 , A61K8/00 , A61K8/18 , A61K8/72 , A61K8/89 , A61K8/92 , A61Q1/00 , A61Q1/02 , A61Q1/12 , A61Q19/00 , C08L83/04 , C08L83/08 , A61K7/00 , A61K7/02 , A61K7/48
Abstract: PURPOSE:To provide a cosmetic good in feeling after use with being smooth to the touch and refreshed, also capable of preventing makeup spoilage due to sebum, thus capable of sustaining initial makeup situation, consisting of a combination of a specific organopolysiloxane, volatile lubricant and highly oil-absorbing powder. CONSTITUTION:The objective cosmetic consisting of a combination of (A) pref. 2-20wt.% of an organopolysiloxane of formula I (R and R are each alkyl; R is alkyl, alkenyl or fluoroalkyl; R is alkyl alkenyl or fluoroalkyl; l is >=2; m is >=3; (l+m) is 5-6000), e.g. a compound of formula II, (B) pref. 0.5-40 wt.% of a volatile lubricant (pref. a combination of a volatile silicone oil with, as necessary, an isoparaffin hydrocarbon) and (C) pref. 5-20wt.% of highly oil- absorbing powder capable of absorbing squalane at >=1.5wt. times its own weight [e.g. an acrylate copolymer composed of structural units of formula III (R is alkylene) and formula IV (R is alkyl), respectively].
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公开(公告)号:JPH05246836A
公开(公告)日:1993-09-24
申请号:JP4506092
申请日:1992-03-03
Applicant: KAO CORP
Inventor: OTA HIROSHI , MINEMATSU YOSHIHIRO
IPC: A61K8/30 , A61K8/00 , A61K8/06 , A61K8/42 , A61K8/68 , A61K8/72 , A61K8/89 , A61K8/891 , A61P17/16 , A61Q19/00 , C08L83/04 , A61K7/48 , A61K7/00
Abstract: PURPOSE:To provide a w/o-type emulsion cosmetic having high moisture- retaining property and applicability and exhibiting excellent and durable skin- protecting effect. CONSTITUTION:The objective who-type emulsion cosmetic contains (A) an amphiphatic lipid at least containing a hydroxyl group, an amide bond and two long-chain hydrocarbon groups, wherein the hydroxyl group and the amide bond are positioned between the above two long-chain hydrocarbon groups, (B) a high-polymer silicone and (C) a volatile silicone.
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公开(公告)号:JPH05155749A
公开(公告)日:1993-06-22
申请号:JP32748491
申请日:1991-12-11
Applicant: KAO CORP
Inventor: MATSUMOTO YASUNOBU , HOSOKAWA MASARU , TAKANABE EISHIN , MINEMATSU YOSHIHIRO
IPC: A61K8/30 , A61K8/00 , A61K8/02 , A61K8/34 , A61K8/60 , A61K8/72 , A61K8/89 , A61Q19/00 , C08L83/12
Abstract: PURPOSE:To provide a face lotion free from irritency and greasiness, favorable in use feeling, excellent in humectancy, appearance and transparency, useful as a nonalcohol-nonoil cosmetic, etc., containing a polyhydric alcohol and polyether-modified silicone oil. CONSTITUTION:The objective face lotion contains (A) pref. 2-20wt.% of a polyhydric alcohol such polyethylene glycol and (B) pref. 0.04-0.4wt.% of a polyether-modified silicone oil such as a compound of the formula (R is 1-4C alkyl; (m) is 5-50; (n) is 2-10; (p is 10-50;(g) is 0-30).
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公开(公告)号:JPS63218609A
公开(公告)日:1988-09-12
申请号:JP5376987
申请日:1987-03-09
Applicant: KAO CORP
Inventor: YANO SHINJI , KAWAMATA AKIRA , MINEMATSU YOSHIHIRO , AKASAKI SHUICHI , ZAMA MITSUKO , IMOKAWA GENJI , TAKAISHI NAOTAKE
IPC: A61K8/30 , A61K8/00 , A61K8/42 , A61K8/68 , A61K31/16 , A61K31/22 , A61P17/00 , A61Q5/00 , A61Q19/00 , C07C67/00 , C07C231/00 , C07C233/18 , C07C233/20 , C07H15/04
Abstract: NEW MATERIAL:The amide derivative of formula I (R and R are straight- or branched-chain saturated or unsaturated hydrocarbon group; the carbon numbers of R and R are 10-26 and 9-25, respectively; X-Z are H, 1-5C alkyl or hydroxyalkyl; X, Y and Z are not H at the same time). EXAMPLE:N-(2-hydroxy-3-hexadecyloxypropyl)-N-2, 3-dihydroxypropyl-hexadeca namide. USE:An active component for external drug for skin exhibiting excellent ameliorating and preventive effect against chapped skin owing to the radically improving effect of the compound on the water-retaining capability of cuticle layer. PREPARATION:The compound of formula I can be produced by acylating a compound of formula II derived from a compound of formula III and a compound of formula IV and selectively hydrolyzing the ester group of the resultant compound of formula V. The above effect can be further improved by the combined use of the compound with a surfactant.
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公开(公告)号:JPH06107531A
公开(公告)日:1994-04-19
申请号:JP25797192
申请日:1992-09-28
Applicant: KAO CORP
Inventor: SHINPOU TSUNEO , KIMURA MITSUTOSHI , MASUDA MITSUHARU , SUZUKI YUJI , MINEMATSU YOSHIHIRO , IMOKAWA GENJI
Abstract: PURPOSE:To obtain a cosmetic for fair skin and beauty having extremely excellent beautifying effect on skin and preventing and treating effect on stain and freckle by sunburn. CONSTITUTION:A cosmetic for fair skin and beauty comprises (A) 0.001-30wt.% one or more selected from L-ascorbic acid and a water-soluble derivative of L-ascorbic acid and (B) 0.001-10wt.% nicotinic acid amide.
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