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公开(公告)号：CA2489167C
公开(公告)日：2010-08-10
申请号：CA2489167
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS WILHELMUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS MARIA , PRUIJN GERARDUS JOZEF MARIA
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：ES2266603T3
公开(公告)日：2007-03-01
申请号：ES02786237
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS M , PRUIJN GERARDUS JOZEF MARIA
Abstract: Una unidad peptídica que comprende una secuencia seleccionada del grupo que consiste en péptido 0002-27 HQKRGCitGWSRAA, péptido 0002-29 HQRRVCitGWSRAA, péptido 0002-31 HQRRTCitGGSRAA, péptido 0002-32 HQRKWCitGASRAA, péptido 0002- 36 HQFRFCitGCitSRAA, péptido 0002-37 HQKWRCitGRSCitAA y péptido 0002-63 HQFRFCitGWSRAA.
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公开(公告)号：SI1456662T1
公开(公告)日：2006-12-31
申请号：SI200230389
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
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Patent Agency Ranking
公开(公告)号：CA2892001A1
公开(公告)日：2003-06-19
申请号：CA2892001
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS WILHELMUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS MARIA , PRUIJN GERARDUS JOZEF MARIA
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：BRPI0214872B1
公开(公告)日：2016-12-13
申请号：BRPI0214872
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： PRUIJN GERARDUS JOZEF MARIA , DRIJFHOUT JAN WOUTER , BOEKEL MARTINUS ADRIANUS MARIA VAN , VENROOIJ WALTHERUS JACOBUS WILHELMUS VAN
Abstract: "métodos de detectar auto-anticorpos de pacientes sofrendo de artrite rumatóide, peptídeo e kit de ensaio". a presente invenção refere-se ao método de detectar auto-anticorpos de pacientes sofrendo de artrite reumatóide. para esta finalidade, de acordo com a invenção, pelo menos duas unidades peptídicas são usadas, das quais pelo menos uma unidade peptídica compreende uma parte não derivada de (pro)filagrina, fibrina, fibrinogênio, vimentina, citoceratina 1 e citoceratina 9, e unidade peptídica esta que compreende o motivo xg, e uma unidade peptídica compreendendo o motivo xnong, em que x é uma citrulina ou um análogo da mesma, e nong é um aminoácido diferente da glicina.
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公开(公告)号：CA2708463C
公开(公告)日：2015-08-11
申请号：CA2708463
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS WILHELMUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS MARIA , PRUIJN GERARDUS JOZEF MARIA
IPC: C07K7/08 , C07K7/06 , C07K7/54 , C07K7/64 , C07K14/47 , C40B30/04 , G01N33/53 , G01N33/564 , G01N33/68
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：AT329267T
公开(公告)日：2006-06-15
申请号：AT02786237
申请日：2002-12-11
Applicant: STICHTING TECH WETENSCHAPP
Inventor： VAN VENROOIJ WALTHERUS JACOBUS , DRIJFHOUT JAN WOUTER , VAN BOEKEL MARTINUS ADRIANUS M , PRUIJN GERARDUS JOZEF MARIA
Abstract: The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)fillaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrullin or an analogue thereof, and nonG is an amino acid other than glycine.
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公开(公告)号：NL1019540C2
公开(公告)日：2003-07-01
申请号：NL1019540
申请日：2001-12-11
Applicant: STICHTING TECH WETENSCHAPP
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