Patent search ap:("VERTEX PHARMA") AND inv:"CONNELLY PATRICK" Page 2

11.

发明专利
SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE 未知

公开(公告)号：AU2020201314A1

公开(公告)日：2020-03-12

申请号：AU2020201314

申请日：2020-02-21

Applicant: VERTEX PHARMA

Inventor： HURTER PATRICIA , CONNELLY PATRICK , ROWE WILLIAM , YOUNG CHRISTOPHER R , COSTACHE ADRIANA , KRAWIEC MARIUSZ , GONG YUCHUAN , FENG YUSHI , TRUDEAU MARTIN

IPC: A61K31/445

Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5 hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.

12.

发明专利
SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE 未知

公开(公告)号：AU2018204203A1

公开(公告)日：2018-07-05

申请号：AU2018204203

申请日：2018-06-13

Applicant: VERTEX PHARMA

Inventor： HURTER PATRICIA , CONNELLY PATRICK , ROWE WILLIAM , YOUNG CHRISTOPHER R , COSTACHE ADRIANA , KRAWIEC MARIUSZ , GONG YUCHUAN , FENG YUSHI , TRUDEAU MARTIN

IPC: A61K31/445

Abstract: The present invention relates to solid state forms of N-[2,4-bis(1 ,1 -dimethylethyl)-5 hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.

13.

发明专利
N-[2,4-bisz(1,1-dimetil-etil)-5-hidroxi-fenil]-1,4-dihidro-4-oxo-kinolin-3-karboxamid szilárd formái 未知

公开(公告)号：HUE032813T2

公开(公告)日：2017-11-28

申请号：HUE06848237

申请日：2006-12-28

Applicant: VERTEX PHARMA

Inventor： HURTER PATRICIA , GONG YUCHUAN , YOUNG CHRISTOPHER R , CONNELLY PATRICK , ROWE WILLIAM , COSTACHE ADRIANA , KRAWIEC MARIUSZ , FENG YUSHI , TRUDEAU MARTIN

14.

发明专利
STAŁE POSTACIE N-[2,4-BIS(1,1-DIMETYLOETYLO)-5-HYDROKSYFENYLO]-1,4- DIHYDRO-4-OKSOCHINOLINO-3-KARBOKSYAMIDU 未知

公开(公告)号：PL1993360T3

公开(公告)日：2017-08-31

申请号：PL06848237

申请日：2006-12-28

Applicant: VERTEX PHARMA

Inventor： HURTER PATRICIA , GONG YUCHUAN , YOUNG CHRISTOPHER R , CONNELLY PATRICK , ROWE WILLIAM , COSTACHE ADRIANA , KRAWIEC MARIUSZ , FENG YUSHI , TRUDEAU MARTIN

IPC: C07D215/56 , A61K31/445

15.

发明专利
SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE 未知

公开(公告)号：AU2016219571A1

公开(公告)日：2016-09-08

申请号：AU2016219571

申请日：2016-08-23

Applicant: VERTEX PHARMA

Inventor： HURTER PATRICIA , CONNELLY PATRICK , ROWE WILLIAM , YOUNG CHRISTOPHER R , COSTACHE ADRIANA , KRAWIEC MARIUSZ , GONG YUCHUAN , FENG YUSHI , TRUDEAU MARTIN

IPC: A61K31/445

Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1 -dimethylethyl)-5 hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.

16.

发明专利
Forms and Formulations of VX-950 未知

公开(公告)号：NZ588471A

公开(公告)日：2012-02-24

申请号：NZ58847105

申请日：2005-06-08

Applicant: VERTEX PHARMA

Inventor： MURPHY MAURA , DINEHART KIRK , HURTER PATRICIA , CONNELLY PATRICK , CUI YONG

IPC: A01N43/40 , A61K9/14 , A61K9/48 , A61K31/454 , A61K45/06

Abstract: Disclosed herein are solid dispersion comprising VX-950 (telaprevir) and a polymer, particularly hydroxyproplymethylcellulose (HPMC) or hydroxypropylmethylcellulose acetate succinate (HPMCAS), wherein the solid dispersion is obtained by spray drying and a polymer is present in an amount from about 10% by weight to about 80% by weight. Said forms and formulations disclosed herein have improved bioavailability relative to crystalline VX-950 and are useful for treating HCV infection.

17.

发明专利
Pharmaceutical compositions 未知

公开(公告)号：ZA200802676B

公开(公告)日：2009-12-30

申请号：ZA200802676

申请日：2008-03-26

Applicant: VERTEX PHARMA

Inventor： MURPHY MAURA , DINEHART KIRK , HURTER PATRICIA , CONNELLY PATRICK , CUI YONG , PANICUCCI RICCARDO N

IPC: A61K20100101 , A61K9/14 , A61K31/454 , A61K45/06

Abstract: Forms and formulations of VX-950 and uses thereof.

18.

发明专利
未知

公开(公告)号：NO20070130A

公开(公告)日：2007-01-25

申请号：NO20070130

申请日：2007-01-08

Applicant: VERTEX PHARMA

Inventor： MURPHY MAURA , DINEHART KIRK , HURTER PATRICIA , CONNELLY PATRICK , CUI YONG

IPC: A61K9/20 , A61K9/14 , A61K9/48 , A61K31/454 , A61K45/00 , A61K45/06 , A61P31/12

CPC classification number: A61K38/07 , A61K9/145 , A61K9/146 , A61K9/1635 , A61K9/1652 , A61K31/497 , A61K45/06

19.

发明专利
SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE 未知

公开(公告)号：AU2020201314B2

公开(公告)日：2022-02-03

申请号：AU2020201314

申请日：2020-02-21

Applicant: VERTEX PHARMA

Inventor： HURTER PATRICIA , CONNELLY PATRICK , ROWE WILLIAM , YOUNG CHRISTOPHER R , COSTACHE ADRIANA , KRAWIEC MARIUSZ , GONG YUCHUAN , FENG YUSHI , TRUDEAU MARTIN

IPC: A61K31/445

Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5 hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.

20.

发明专利
FARMACEUTSKI SASTAVI AMORFNOG OBLIKA N-[2,4-BIS(1,1-DIMETILETIL)-5-HIDROKSIFENIL]-1,4-DIHIDRO-4-OKSOKINOLIN-3-KARBOKSAMIDA 未知

公开(公告)号：HRP20200708T1

公开(公告)日：2020-07-24

申请号：HRP20200708

申请日：2020-05-04

Applicant: VERTEX PHARMA

Inventor： HURTER PATRICIA , GONG YUCHUAN , YOUNG CHRISTOPHER R , CONNELLY PATRICK , ROWE WILLIAM , COSTACHE ADRIANA , KRAWIEC MARIUSZ , FENG YUSHI , TRUDEAU MARTIN

IPC: C07D215/56 , A61K31/445

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