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公开(公告)号:IL201550A
公开(公告)日:2015-10-29
申请号:IL20155009
申请日:2009-10-15
Applicant: MICELL TECHNOLOGIES INC
IPC: A61F2/82 , A61L20060101
Abstract: Provided herein is a coated coronary stent, comprising: a. stent framework; b. a plurality of layers deposited on said stent framework to form said coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.
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公开(公告)号:AU2011256902B2
公开(公告)日:2015-03-12
申请号:AU2011256902
申请日:2011-12-16
Applicant: MICELL TECHNOLOGIES INC
Inventor: TAYLOR CHARLES DOUGLAS , MCCLAIN JAMES B , SMOKE CLINT , COLE MICHAEL E , DEYOUNG JAMES
Abstract: C:\Documnsand Scuin\pSXD\LalSettins\Tcmp\DcsCorp\OCR\3AGEo IOCRdo-L2/620II A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate; wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent. 4-j 4-04 = ) I -j co0 xo: uit
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公开(公告)号:CA2905419A1
公开(公告)日:2014-10-09
申请号:CA2905419
申请日:2014-03-12
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR CHARLES DOUGLAS , BURGERMEISTER ROBERT STEVEN
IPC: A61F2/00
Abstract: A bioabsorbable biomedical implant is disclosed. The implant includes a tubular scaffold comprising a plurality of interconnected polymer struts. The interconnected polymer struts defines a plurality of deformable cells. The polymer struts have an average strut thickness of no more than about 120 µ??. Methods for making the bioabsorbable biomedical implant, including the methods for making the polymer materials for the tubular scaffold, are also disclosed.
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公开(公告)号:CA2684482C
公开(公告)日:2014-08-12
申请号:CA2684482
申请日:2008-04-17
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR DOUGLAS
Abstract: Provided herein is a coated coronary stent, comprising:. a. stent framework; b. a plurality of layers deposited on said stent framework to form said coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.
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公开(公告)号:CA2852260A1
公开(公告)日:2013-04-25
申请号:CA2852260
申请日:2012-10-18
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR CHARLES DOUGLAS
IPC: A61M31/00
Abstract: A medical device that releases a pharmaceutical agent to a target site is disclosed. The medical device includes a balloon, and a coating on at least a portion of the balloon. Each particle of the particles of the pharmaceutical agent is at least partially encapsulated in a polymer layer. The method includes the steps of providing a device including a balloon, and a coating on at least a portion of the balloon, the coating including particles of a pharmaceutical agent, and each particle of the pharmaceutical agent is at least partially encapsulated in a polymer layer; positioning the device to allow the balloon to reach the target site; and inflating the balloon of the device.
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公开(公告)号:AU2011232760A1
公开(公告)日:2011-10-27
申请号:AU2011232760
申请日:2011-10-05
Applicant: MICELL TECHNOLOGIES INC
Inventor: DOUG TAYLOR , JIM MCCLAIN , CLINT SMOKE , MIKE COLE , JAMES DEYOUNG
Abstract: C:NRPobWCC\SXD\3914539_ .DOC-5/10/201I A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical 5 agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do I0 not substantially modify the morphology of said pharmaceutical agent.
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公开(公告)号:ZA200907548B
公开(公告)日:2010-07-28
申请号:ZA200907548
申请日:2009-10-27
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR DOUGLAS
IPC: A61F20100101 , A61L20100101
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公开(公告)号:CA2688314A1
公开(公告)日:2008-12-04
申请号:CA2688314
申请日:2008-05-23
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES , TAYLOR DOUGLAS
Abstract: A method for depositing a coating comprising a polymer and impermeable di spersed solid on a substrate, comprising the following steps: discharging at least one impermeable dispersed solid in dry powder form through a first or ifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or impermeable dispersed solid particles onto said substrate, wherein an electrical potential is maintained between the substrate and the impermeable dispersed solid and/or polymer particles, thereby forming said coating; and sintering said coating under conditions th at do not disrupt the activity and/or function of the substrate. A similar m ethod is provided for depositing a coating comprising a hydrophobic polymer and a water-vapor-trapping material on a substrate.
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公开(公告)号:CA2679712A1
公开(公告)日:2008-07-17
申请号:CA2679712
申请日:2008-01-08
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR DOUGLAS , RABINER ROBERT
IPC: A61F2/06
Abstract: A method for preparing a laminate coronary stent comprising: providing a stent framework; and depositing a plurality of layers on said stent framewor k to form said laminate coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer.
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公开(公告)号:DE60018407D1
公开(公告)日:2005-04-07
申请号:DE60018407
申请日:2000-05-12
Applicant: MICELL TECHNOLOGIES INC
Abstract: A system for the controlled addition of detergent formulations and the like to a carbon dioxide cleaning apparatus comprises: (a) a high pressure wash vessel; (b) an auxiliary vessel; (c) a drain line connecting the auxiliary vessel to the wash vessel; (d) optionally but preferably, a separate vent line connecting the auxiliary vessel to the wash vessel; (e) a detergent reservoir; and (f) a detergent supply line connecting the detergent reservoir to the auxiliary vessel. An advantage of this apparatus is that, because the detergent formulation can be pumped into the auxiliary vessel in a predetermined aliquot or amount, which predetermined aliquot or amount can then be transferred into the wash vessel where it combines with the liquid carbon dioxide cleaning solution, the detergent formulation can be added to the cleaning solution in a more controlled or accurate manner. An alternate embodiment adapted for the addition of aqueous detergent formulations and the like to a carbon dioxide dry cleaning system under turbulent conditions comprises: (a) a high pressure wash vessel; (b) a filter; (c) a carbon dioxide cleaning solution drain line interconnecting the wash vessel to the filter; (d) a carbon dioxide cleaning solution supply line connecting the filter to the wash vessel; (e) a first high pressure pump (i.e., a pump that is capable of pumping liquid solutions comprising liquid carbon dioxide) operably connected to the drain line; (f) a detergent formulation reservoir; (g) a detergent formulation supply line connecting the reservoir to the carbon dioxide cleaning solution supply line; and (h) a second high pressure pump operably connected to the detergent formulation supply line for transferring detergent formulation from the detergent formulation reservoir into the carbon dioxide cleaning solution under turbulent conditions.
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