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公开(公告)号：KR1020100006599A
公开(公告)日：2010-01-21
申请号：KR1020080066783
申请日：2008-07-10
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing dried powder and extract of chub mackerel fraction is provided to reduce total cholesterol and blood triglyceride content. CONSTITUTION: A pharmaceutical composition for preventing and treating hyperlipidemia contains 0.1-50 weight% of dried powder or extract of chub mackerel fraction as an active ingredient. The fraction of the chub mackerel is head, cartilage, shell, muscle, eye, gill, total body of the fish. A method for preparing the dried powder of chub mackerel fraction comprises: a step of washing and removing foreign material and salt from the chub mackerel; and a step of cutting head, cartilage, shell, muscle, eye, gill, and total body. The extract is isolated using water, alcohol and spirit extract solvent.
Abstract translation: 目的：提供含有干粉的组合物和鲭鱼and提取物，以降低总胆固醇和血甘油三酯含量。 构成：用于预防和治疗高脂血症的药物组合物含有0.1-50重量％的干燥粉末或作为活性成分的鲭鱼片提取物。 小鲭鱼的分数是头，软骨，壳，肌肉，眼睛，鳃，鱼的全身。 一种制备鲭鱼m the干燥粉末的方法，包括：从鲭鱼鲭鱼中洗涤除去异物和盐的步骤; 并切割头，软骨，壳，肌肉，眼睛，鳃和全身的一个步骤。 使用水，酒精和精油提取物溶剂分离提取物。
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公开(公告)号：KR1020090105984A
公开(公告)日：2009-10-08
申请号：KR1020080031422
申请日：2008-04-04
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A method for manufacturing collagen isolated from the skin of bigeye tuna is provided to produce high quality of collagen with high solubility and emulsion stability. CONSTITUTION: A method for manufacturing collagen isolated from the skin of bigeye tuna comprises: a step for washing the skin of the bigeye tuna which is stored at -30 °C to -100 °C; a step for treating the skin with 0.05 ~ 10.0 %(w/v) of alkali solution; a step for washing and neutralizing with distilled water; a step for adding 0.05 ~ 10.0 N of acid to the skin, then stirring and extracting; a step for separating extracted liquid and residue using a centrifuge; and a step for drying to obtain acid soluble collagen (AC); a step for adding 0.5 ~ 5.0 N of acid; a step for adding 0.5 ~ 10% of pepsin and stirring and hydrolyzing for 1 to 60 hours; a step for separating extract liquid and residue using a filter; a step for adding NaCl to adjust the concentration to 1-10 % and neutralizing precipitates; and a step for freeze-drying to obtain a pepsin soluble collagen (PC).
Abstract translation: 目的：提供从大眼金枪鱼皮肤分离的胶原蛋白的制造方法，以生产高质量的胶原蛋白，具有高溶解性和乳液稳定性。 构成：从大眼金枪鱼皮肤分离的胶原蛋白的制造方法，其特征在于，包括：在-30℃-100℃保存的大眼金枪鱼皮肤的洗涤步骤; 用0.05〜10.0％（w / v）碱溶液处理皮肤的步骤; 用蒸馏水洗涤和中和的步骤; 向皮肤中加入0.05〜10.0N的酸，然后搅拌和提取; 使用离心机分离提取液和残渣的步骤; 和干燥以获得酸溶性胶原（AC）的步骤; 添加0.5〜5.0 N酸的步骤; 加入0.5〜10％胃蛋白酶，搅拌水解1〜60小时; 使用过滤器分离提取液和残渣的步骤; 添加NaCl以将浓度调节至1-10％并中和沉淀的步骤; 和冷冻干燥步骤以获得胃蛋白酶可溶性胶原（PC）。
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23.发明公开기능성 성분이 다량 함유된 오징어젓 추출물의 제조방법 및 이를 함유하는 조성물 无效一种制备含有包含功能成分的ID AN AN A A A A A A AME AME AME AME AME AME AME AME AME AME AME AME AME AME AME AME AME AME AME AME AME AME AME
公开(公告)号：KR1020120107023A
公开(公告)日：2012-09-28
申请号：KR1020110022689
申请日：2011-03-15
Applicant: 강릉원주대학교산학협력단
CPC classification number: A23L17/50 , A23V2002/00 , A23V2200/30
Abstract: PURPOSE: A producing method of a salted squid extract containing the abundant amount of functional components, and a composition containing thereof are provided to offer an arteriosclerosis prevention effect to users. CONSTITUTION: A producing method of a salted squid extract containing the abundant amount of functional components comprises the following steps: salting washed, assorted, and cut squid for 1-7 days at 1-40 deg C; washing the salted squid, and mixing the squid with sugar and starch syrup; mixing the sugar-soaked squid with red pepper powder, garlic, ginger, artificial seasoning, and the starch syrup, and aging the mixture at 1-20 deg C for 1-40 days to obtain salted squid product; freezing the salted squid product, and vacuum-freezing the salted squid product; extracting the vacuum-frozen salted squid product with an organic solvent; and separating the obtained extract into the extract and insoluble extraction residues. The insoluble extraction residues are insoluble to polar solvents.
Abstract translation: 目的：提供含有大量功能成分的盐鱿鱼提取物的制备方法和含有其的组合物，以向使用者提供动脉硬化预防效果。 构成：含有大量功能成分的盐鱿鱼提取物的生产方法包括以下步骤：在1-40℃下将洗涤的，分类的和鱿鱼腌制1-7天; 清洗盐鱿鱼，并将鱿鱼与糖和淀粉糖浆混合; 将含糖的鱿鱼与红辣椒粉，大蒜，姜，人造调味料和淀粉糖浆混合，并将混合物在1-20℃下老化1-40天，得到盐鱿鱼制品; 冷冻鱿鱼制品，真空冷冻鱿鱼制品; 用有机溶剂提取真空冷冻的盐鱿鱼产品; 并将得到的提取物分离成提取物和不溶性提取残渣。 不溶性萃取残渣不溶于极性溶剂。
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公开(公告)号：KR101182059B1
公开(公告)日：2012-09-11
申请号：KR1020090106646
申请日：2009-11-05
Applicant: 강릉원주대학교산학협력단
Abstract: 본 발명은 항산화 활성을 갖는 톳 추출물을 유효성분으로 함유하는 산화적 스트레스 관련 질환의 예방 및 치료를 위한 조성물에 관한 것으로, 상세하게는 본 발명의 톳 추출물은 DPPH 라디칼 소거능 실험에서 강력한 자유 라디칼 소거 작용을 나타내는 바, 항산화 활성을 증진시킴을 확인한 바, 산화적 스트레스 관련의 예방 및 치료에 유용한 약학조성물 및 건강기능식품에 이용될 수 있다.
톳, 산화적 스트레스 관련, 라디칼, 항산화-
公开(公告)号：KR101068709B1
公开(公告)日：2011-09-28
申请号：KR1020110044668
申请日：2011-05-12
Applicant: 강릉원주대학교산학협력단
IPC: A61K35/618 , A23L1/30
Abstract: 본 발명은 가리비 성분을 유효성분으로 함유하는 조성물에 관한 것으로, 상세하게는 본 발명의 가리비 성분은 혈장 응고 억제효과를 확인함으로써, 이를 포함하는 조성물은 혈전 관련 질환의 예방 및 치료를 위한 약학 조성물 또는 건강기능식품으로 유용하게 이용될 수 있다.
Abstract translation: 本发明涉及含有该DAG组分作为有效成分，特别是药物组合物或通过本发明的DAG组分的预防和治疗确定血浆凝固的抑制作用，含有它们的组合物是血栓形成相关病症的组合物 它可以有用地用作保健功能食品。
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Patent Agency Ranking26.发明授权꽁치 분획 건조 분말 또는 그 추출물을 유효성분으로함유하는 고지혈증의 예방 및 치료용 조성물 失效一种组合物，其包含用于预防和治疗高脂血症的SauryColoabis saira级分的干燥粉末或其提取物
公开(公告)号：KR101021718B1
公开(公告)日：2011-03-15
申请号：KR1020080067215
申请日：2008-07-10
Applicant: 강릉원주대학교산학협력단
Abstract: 본 발명은 꽁치 분획 건조 분말 또는 그 추출물을 유효성분으로 함유하는 조성물에 관한 것으로서, 구체적으로 본 발명의 꽁치 분획 건조 분말 또는 그 추출물은 고지혈증 동물모델의 혈중 중성지방 및 혈중 총 콜레스테롤 함량의 감소 효과를 나타냄으로써, 고지혈증의 예방 및 치료용 약학조성물 또는 건강기능식품으로 유용하게 이용될 수 있다.
꽁치, 분획 건조 분말, 추출물, 혈중 중성지방, 혈중 총 콜레스테롤, 고지혈증-
公开(公告)号：KR1020110022472A
公开(公告)日：2011-03-07
申请号：KR1020090080089
申请日：2009-08-27
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing seaweed extract for preventing and treating hypertension is provided to suppress angiotensin-converting enzyme(ACE) and ensure high stability. CONSTITUTION: A pharmaceutical composition for preventing and treating hypertension contains seaweed extract as an active ingredient. The seaweed includes Natural Undaria pinnatifida, Cultural Undaria pinnatifida, Laminaria japonica, Sporophyll of Undaria pinnatifida, or Agarum cribrosum. The seaweed extract is obtained suing water including purified water, low alcohol of C1-C4, or mixture solvent thereof. A health food for preventing and treating hypertension contains seaweed extract as an active ingredient. The health food is manufactured in the form of powder, granule, tablet, capsule, or beverage.
Abstract translation: 目的：提供含有预防和治疗高血压的海藻提取物的组合物，用于抑制血管紧张素转换酶（ACE），保证高度的稳定性。 构成：用于预防和治疗高血压的药物组合物含有海藻提取物作为活性成分。 海藻包括天然pin includes，文化pin ida，j ica，pin，，，，。。。。。。。。。。。。。。。。。。。。。。。。 得到海藻提取液，其中包括净化水，C1-C4的低级醇或其混合溶剂。 用于预防和治疗高血压的保健食品含有海藻提取物作为活性成分。 保健食品以粉末，颗粒，片剂，胶囊或饮料的形式制造。
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公开(公告)号：KR1020110022411A
公开(公告)日：2011-03-07
申请号：KR1020090079992
申请日：2009-08-27
Applicant: 강릉원주대학교산학협력단
IPC: A61K35/618 , A61K9/14 , A23L33/00
CPC classification number: A61K35/618 , A23L33/00 , A61K9/14
Abstract: PURPOSE: A composition containing Patinopecten yessoensis ingredient is provided to prevent and treat liver diseases due to oxidative stress without side effects or toxicity. CONSTITUTION: A pharmaceutical composition for preventing and treating oxidative stress contains Patinopecten yessoensis ingredient as an active ingredient. The Patinopecten yessoensis ingredient is obtained from dried adductor muscle powder of Patinopecten yessoensis, dried residue powder of Patinopecten yessoensis, adductor muscle extract of Patinopecten yessoensis, or residue extract of Patinopecten yessoensis. The adduct muscle extract of Patinopecten yessoensis is obtained using water including purified water, low alcohol of 1-4 carbon atoms, or mixture solvent thereof. The Patinopecten yessoensis is Patinopecten yessoensis, Pecten albicans, Chlamys farreri, Chlamys swifti, Patinopecten (Mizuhopecten) tokyoensis, or Lima sowerbyi.
Abstract translation: 目的：提供含有Patinopecten yessoensis成分的组合物，用于预防和治疗由于氧化应激引起的肝脏疾病，无副作用或毒性。 构成：用于预防和治疗氧化应激的药物组合物含有作为活性成分的Patinopecten yessoensis成分。 Patinopecten yessoensis成分是从干燥的内收肌肌肉粉，Patinopecten yessoensis的干燥残留粉末，Patinopecten yessoensis的内收肌提取物或Patinopecten yessoensis的残留提取物获得的。 使用包括纯化水，1-4个碳原子的低级醇或其混合溶剂在内的水可得到Pat藜皂甙的加合肌肉提取物。 Patinopecten yessoensis是Patinopecten yessoensis，Pecten albicans，Chlamys farreri，Chlamys swifti，Patinopecten（Mizuhopecten）tokyoensis或Lima sowerbyi。
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公开(公告)号：KR1020110001317A
公开(公告)日：2011-01-06
申请号：KR1020090058800
申请日：2009-06-30
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing fermented Theragra chalcogramma is provided to prevent and treat liver diseases caused by oxidative stress. CONSTITUTION: A pharmaceutical composition for preventing and treating liver diseases caused by oxidative stress contains 0.1-50 weight% of fermented Theragra chalcogramma as an active ingredient. The fermented Theragra chalcogramma is dried powder or extract of fermented Theragra chalcogramma. The extract of fermented Theragra chalcogramma is a polar solvent insoluble extract residue. A health food for preventing and treating liver diseases contains fermented Theragra chalcogramma as an active ingredient. The health food is used in the form of powder, granule, tablet, capsule, syrup or beverage.
Abstract translation: 目的：提供含有发酵的Theragra chalcogramma的组合物，用于预防和治疗由氧化应激引起的肝脏疾病。 构成：用于预防和治疗由氧化应激引起的肝脏疾病的药物组合物含有0.1-50重量％的发酵的Theragra chalcogramma作为活性成分。 发酵的Theragra chalcogramma是发酵的Theragra chalcogramma的干粉或提取物。 发酵的Theragra chalcogramma的提取物是极性溶剂不溶性提取物残留物。 用于预防和治疗肝脏疾病的保健食品含有发酵的Theragra chalcogramma作为活性成分。 保健食品以粉末，颗粒，片剂，胶囊，糖浆或饮料的形式使用。
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公开(公告)号：KR1020110001316A
公开(公告)日：2011-01-06
申请号：KR1020090058799
申请日：2009-06-30
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing fermented flatfish with grains is provided to reduce activity of AST(aspartic acid transaminase), ALT(alanine transaminase), SDH(Sorbitol dehydrogenase), gamma-GT(gamma-glutamyltransferase), ALP(alkaline phosphatase) and LDH(lactate dehydrogenase) and to prevent and treat liver diseases. CONSTITUTION: A pharmaceutical composition for preventing and treating liver diseases caused by oxidative stress contains 0.01-50 weight of fermented flatfish with grains as an active ingredient. The fermented flatfish with grains is a dried powder or extract of fermented flatfish with grains. The extract of fermented flatfish with grains is polar solvent insoluble extract residue. A health food for preventing and treating liver disease caused by oxidative stress contains fermented flatfish with grains as an active ingredient. The health food is used in the form of powder, granule, tablet, capsule, syrup or beverage.
Abstract translation: 目的：提供含有谷物发酵鲽鱼的组合物，以降低AST（天冬氨酸转氨酶），ALT（丙氨酸转氨酶），SDH（山梨醇脱氢酶），γ-GT（γ-谷氨酰转移酶），ALP（碱性磷酸酶）和LDH （乳酸脱氢酶）和预防和治疗肝脏疾病。 构成：用于预防和治疗由氧化应激引起的肝脏疾病的药物组合物含有0.01-50重量的以谷物为活性成分的发酵鲽鱼。 发酵的鲽鱼与谷物是干粉或发酵鲽的提取物与谷物。 发酵鲽鱼提取物为极性溶剂不溶性提取物残渣。 用于预防和治疗由氧化应激引起的肝脏疾病的保健食品包含以谷物为活性成分的发酵鲽鱼。 保健食品以粉末，颗粒，片剂，胶囊，糖浆或饮料的形式使用。
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