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    회향 추출물을 함유하는 충치 예방용 구강 조성물 및항균용 조성물
    21.
    发明公开
    회향 추출물을 함유하는 충치 예방용 구강 조성물 및항균용 조성물 有权
    用于预防含有提取物的药物的抗菌组合物和口服组合物

    公开(公告)号：KR1020080112024A

    公开(公告)日：2008-12-24

    申请号：KR1020070060726

    申请日：2007-06-20

    Applicant: 강원대학교산학협력단 ,  (주)에스.앤.디

    Inventor： 이해익 ,  여경목 ,  권상오 ,  김복남 ,  김상무

    IPC: A61K8/97 ,  A61K36/235 ,  A61Q11/00

    Abstract: An oral composition for preventing tooth-decay, containing fennel extract and an antibiotic composition is provided to be stable at a high temperature and to perform processing at a temperature of wide range. An oral composition for preventing tooth-decay comprises FENNEL extract by hot water and FENNEL extract by organic solvent as an active ingredient. The oral composition comprises one formulation selected from a group consisting of oral cleaner, dentifrice, gum, candy, jelly and chocolate. The organic solvent is selected from a group consisting of C1-C6 alcohol, acetone, ether, benzene, chloroform, ethylacetate, methylene chloride, hexane, cyclohexane, and petroleum ether.

    Abstract translation: 提供含有茴香提取物和抗生素组合物的防止牙齿腐烂的口腔用组合物，使其在高温下稳定，在宽范围的温度下进行处理。 用于防止牙齿衰变的口腔用组合物包含通过热水的FENNEL提取物和通过有机溶剂的FENNEL提取物作为活性成分。 口腔组合物包含选自口腔清洁剂，洁牙剂，口香糖，糖果，果冻和巧克力的一种制剂。 有机溶剂选自C1-C6醇，丙酮，醚，苯，氯仿，乙酸乙酯，二氯甲烷，己烷，环己烷和石油醚。

    페닐아마이드 화합물을 유효성분으로 하는 고지혈증 치료용 복합 생약 추출물
    26.
    发明公开
    페닐아마이드 화합물을 유효성분으로 하는 고지혈증 치료용 복합 생약 추출물 有权
    用于治疗高脂血症的复杂提取物

    公开(公告)号：KR1020130025421A

    公开(公告)日：2013-03-11

    申请号：KR1020130010580

    申请日：2013-01-30

    Applicant: (주)에스.앤.디

    Inventor： 여경목 ,  최상원 ,  권상오 ,  김복남 ,  김동희

    IPC: A61K31/4045 ,  A61K31/135 ,  A61K36/286 ,  A61K36/906

    CPC classification number: A61K31/4045 ,  A61K31/165 ,  A61K36/286 ,  A61K36/906 ,  A61K2300/00

    Abstract: PURPOSE: A complex crude drug extract containing a phenylamide compound is provided to reduce side effects and toxicity, and to treat hyperlipidemia. CONSTITUTION: A complex crude drug extract for treating hyperlipidemia contains a serotonin derivative and a tyramine derivative in a weight ratio of 4:1. The serotonin derivative is N-(p-coumaroyl)serotonin(CS), N-feruloylserotonin(FS), or a mixture thereof. The tyramine derivative is dihydro-N-caffeoyltyramine(DCT), trans-N-caffeoyltyramine(t-CT), or a mixture thereof. [Reference numerals] (AA) Ginger + Safflower seed; (BB) Ginger 1 : Safflower seed B8; (CC) Ginger 1 : Safflower seed B4; (DD) Ginger 1 : Safflower seed B2; (EE) Ginger 1 : Safflower seed B1; (FF) Ginger 2 : Safflower seed B1; (GG) Ginger 4 : Safflower seed B1; (HH) Ginger 8 : Safflower seed B1; (II) Ginger 1 : Safflower seed A1; (JJ) Ginger 2 : Safflower seed A1; (KK) Ginger 4 : Safflower seed A1; (LL) Ginger 8 : Safflower seed A1

    Abstract translation: 目的：提供含有苯酰胺化合物的复合生物药物提取物，以减少副作用和毒性，并治疗高脂血症。 构成：用于治疗高脂血症的复杂生药提取物含有重量比为4:1的5-羟色胺衍生物和酪胺衍生物。 5-羟色胺衍生物是N-（对 - 香豆酰基）5-羟色胺（CS），N-亚铁血清素（FS）或其混合物。 酪胺衍生物是二氢-N-咖啡酰基酪氨酸（DCT），反式N-咖啡酰酪胺（t-CT）或其混合物。 （标号）（AA）姜+红花种子; （BB）姜1：红花种子B8; （CC）姜1：红花籽B4; （DD）姜1：红花籽B2; （EE）姜1：红花籽B1; （FF）姜2：红花籽B1; （GG）姜4：红花籽B1; （HH）姜8：红花籽B1; （二）姜1：红花籽A1; （JJ）姜2：红花籽A1; （KK）姜4：红花籽A1; （LL）姜8：红花籽A1

    페닐아마이드 화합물을 유효성분으로 하는 고지혈증 치료용 복합 생약 추출물
    27.
    发明公开
    페닐아마이드 화합물을 유효성분으로 하는 고지혈증 치료용 복합 생약 추출물 无效
    用于治疗高脂血症的复杂提取物

    公开(公告)号：KR1020120115060A

    公开(公告)日：2012-10-17

    申请号：KR1020110071839

    申请日：2011-07-20

    Applicant: (주)에스.앤.디

    Inventor： 여경목 ,  최상원 ,  권상오 ,  김복남 ,  김동희

    IPC: A61K36/286 ,  A61K36/906 ,  A61P3/06

    Abstract: PURPOSE: A complex crude drug extract for treating hyperlipidemia which contains phenyl amide compound is provided to show HMG-CoR inhibition effects and ACAT inhibition effects related to treat and prevent the hyperlipidemia. CONSTITUTION: A complex crude drug extract for treating hyperlipidemia is composed of multiple extract of safflower seed and ginger. The mixing ratio of the safflower seed to ginger is 4:1 in the weight ratio. The Lycii Radicis Cortex extract is additionally added to the extract. The mixing ration of the safflower seed, ginger extract, and the Lycii Radicis Cortex extract is 5:1:1 in the weight ratio. The complex crude drug extract for treating hyperlipidemia is composed of serotonin derivative and tyramine derivative. The mixing ratio of serotonin derivative to the tyramine derivative is 4: 1 in the weight ratio. The serotonin derivative is a mixture of N-(p-coumaroyl) serotonin(CS), N- feruloylserotonin(FS), or a mixture thereof. [Reference numerals] (AA) Ginger+safflower seed; (BB) Ginger 1 : Safflower seed B3; (CC) Ginger 1 : Safflower seed B4; (DD) Ginger 1 : Safflower seed B2; (EE) Ginger 1 : Safflower seed B1; (FF) Ginger 2 : Safflower seed B1; (GG) Ginger 4 : Safflower seed B1; (HH) Ginger 8 : Safflower seed B1; (II) Ginger 1 : Safflower seed A1; (JJ) Ginger 2 : Safflower seed A1; (KK) Ginger 4 : Safflower seed A1; (LL) Ginger 8 : Safflower seed A1

    Abstract translation: 目的：提供一种用于治疗含有苯酰胺化合物的高脂血症的复合生药提取物，以显示与治疗和预防高脂血症相关的HMG-CoR抑制作用和ACAT抑制作用。 构成：用于治疗高脂血症的复方生药提取物由红花种子和姜的多次提取物组成。 红花种子与姜的混合比例为4：1。 提取物中还加入Lycii Radicis Cortex提取物。 红花种子，姜提取物和堇菜提取物的混合比例为5：1：1。 用于治疗高脂血症的复方生药提取物由5-羟色胺衍生物和酪胺衍生物组成。 5-羟色胺衍生物与酪胺衍生物的混合比例为重量比为4:1。 5-羟色胺衍生物是N-（对 - 香豆酰基）5-羟色胺（CS），N-阿魏酰基血清素（FS）或其混合物的混合物。 （标号）（AA）姜+红花种子; （BB）姜1：红花籽B3; （CC）姜1：红花籽B4; （DD）姜1：红花籽B2; （EE）姜1：红花籽B1; （FF）姜2：红花籽B1; （GG）姜4：红花籽B1; （HH）姜8：红花籽B1; （二）姜1：红花籽A1; （JJ）姜2：红花籽A1; （KK）姜4：红花籽A1; （LL）姜8：红花籽A1

    글루탐산 생성 균주 및 천연 조미소재의 제조방법
    28.
    发明公开
    글루탐산 생성 균주 및 천연 조미소재의 제조방법 有权
    制备生产谷氨酸和挥发材料的复合微生物的方法

    公开(公告)号：KR1020120076107A

    公开(公告)日：2012-07-09

    申请号：KR1020100138117

    申请日：2010-12-29

    Applicant: (주)에스.앤.디

    Inventor： 여경목 ,  권상오 ,  김복남

    IPC: C12N1/20 ,  C12P13/14 ,  A23L27/22 ,  C12R1/125

    Abstract: PURPOSE: A method for producing natural seasoning materials using Bacillus subtilis(KFCC 11492P) producing high glutamic acid is provided to supplement and replace chemical seasoning. CONSTITUTION: A Bacillus subtilis(KFCC 11492P) strain produces glutamic acid of high yield. The glutamic acid is prepared by inoculating the strain in a medium containing natural proteins and culturing. A seasoning material contains amino acids and peptides prepared by inoculating the strain in the medium. The medium contains 1-3 weight parts of defatted soybean meal, 1-5 weight parts of wheat gluten, or mixture thereof.

    Abstract translation: 目的：提供使用生产高谷氨酸的枯草芽孢杆菌（KFCC 11492P）生产天然调味料的方法，以补充和替代化学调味料。 构成：枯草芽孢杆菌（KFCC 11492P）菌株产生高产量的谷氨酸。 通过将菌株接种在含天然蛋白质的培养基中并培养来制备谷氨酸。 调味料含有通过将菌株接种在培养基中制备的氨基酸和肽。 该培养基含有1-3重量份脱脂豆粕，1-5重量份小麦面筋或其混合物。

    구강 항균활성을 갖는 잔소리졸의 제조방법
    29.
    发明公开
    구강 항균활성을 갖는 잔소리졸의 제조방법 有权
    具有口服抗生素的西酞菁的制造方法

    公开(公告)号：KR1020110112169A

    公开(公告)日：2011-10-12

    申请号：KR1020100067918

    申请日：2010-07-14

    Applicant: (주)에스.앤.디

    Inventor： 여경목 ,  황재관 ,  권상오 ,  김복남

    IPC: A61K36/9066 ,  A61K31/05 ,  A61P1/02

    CPC classification number: A61K31/05 ,  A61K36/9066 ,  A61K2236/30 ,  A61K2236/51 ,  A61K2236/55

    Abstract: 본 발명은 구강 항균활성을 갖는 잔소리 졸의 제조방법에 관한 것으로, 더욱 상세하게는 커큐마 잔소리자 분말에 유기용매를 혼합하여 항균활성 물질을 추출하는 추출단계, 항균활성 물질이 추출된 유기용매 혼합물을 분리하는 분리단계, 전술한 분리단계를 거쳐 분리된 유기용매 혼합물에 함유된 유기용매를 제거하는 용매제거단계, 유기용매가 제거된 조추출물을 전처리하는 전처리단계, 전처리된 조추출물에 함유된 비극성 물질을 제거하는 비극성물질제거단계, 비극성물질이 제거되어 분획된 추출물을 아세틸레이션하는 아세틸레이션단계, 전술한 아세틸레이션단계를 거친 추출물을 극성차이에 따라 분리하는 항균활성물질분리단계 및 전술한 항균활성물질을 디아세틸레이션하는 디아세틸레이션단계를 포함하여 이루어진다.

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