-
公开(公告)号：AU2007265116A1
公开(公告)日：2008-01-03
申请号：AU2007265116
申请日：2007-06-27
Applicant: ABBOTT LAB
Inventor： GOPALAKRISHNAN SUJATHA , LI JINHE , GUBBINS EARL J , GOPALAKRISHNAN MURALI , GFESSER GREGORY A , FAGHIH RAMIN , MALYSZ JOHN , LYNCH CHRISTOPHER L , KOUHEN RACHID EL
IPC: C07D207/34 , A61K31/402 , A61P25/00 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10
Abstract: The invention relates to a series of substituted pyrrole derivatives, compositions comprising the same, and methods of treating conditions and disorders using such compounds and compositions.
-
22.发明专利
公开(公告)号：HU224827B1
公开(公告)日：2006-02-28
申请号：HU9903530
申请日：1997-05-05
Applicant: ABBOTT LAB , CHILDRENS MEDICAL CENTER
Inventor： DAVIDSON DONALD J , GUBBINS EARL J , WANG JIEYI
IPC: C12N15/09 , C12N15/57 , A61K20060101 , A61K35/14 , A61K38/00 , A61K38/04 , A61K38/48 , A61K39/00 , A61K45/00 , A61K48/00 , A61K101/00 , A61P1/04 , A61P15/18 , A61P17/06 , A61P19/02 , A61P27/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07K1/00 , C07K14/00 , C07K14/47 , C07K14/515 , C07K19/00 , C12N20060101 , C12N9/68 , C12N15/02 , C12P21/06
-
公开(公告)号：BR9708911A
公开(公告)日：1999-08-03
申请号：BR9708911
申请日：1997-05-05
Applicant: ABBOTT LAB
Inventor： DAVIDSON DONALD J , WANG JIEYI , GUBBINS EARL J
IPC: C12N15/09 , A61K20060101 , A61K35/14 , A61K38/00 , A61K38/04 , A61K38/48 , A61K39/00 , A61K45/00 , A61K48/00 , A61K101/00 , A61P1/04 , A61P15/18 , A61P17/06 , A61P19/02 , A61P27/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07K1/00 , C07K14/00 , C07K14/47 , C07K14/515 , C07K19/00 , C12N20060101 , C12N9/68 , C12N15/02 , C12N15/57 , C12P21/06
Abstract: Compounds of formulae (I) and (II), and their salts, esters and prodrugs, are new: A-B-C-X-Y (I); A-B1-C1-X1-Y (II); A = absent or a nitrogen-protecting group; Y = absent or a carboxy-protecting group; B = absent or 1-197 naturally occurring amino acids (aa) corresponding to residues 334-530 of the 791 aa human plasminogen (hPA) sequence given in the specification; C = Lys-R2-R3-Asp; R2 = Leu or Arg; R3 = Tyr, 3-iodotyrosinyl (ITyr) or Phe; X = absent or is 1-12 naturally occurring aa corresponding to residues 535-546 of hP and its homologues or analogues; B1 = absent or is 1-176 aa corresponding to residues 334-513 of hP; C1 = the 514-523 aa sequence of hP; X1 = absent or is 1-10 aa corresponding to residues 524-533 of hP.
-
公开(公告)号：AT513908T
公开(公告)日：2011-07-15
申请号：AT05106596
申请日：1997-05-05
Applicant: ABBOTT LAB
Inventor： DAVIDSON DONALD J , WANG JIEYI , GUBBINS EARL J
Abstract: Mammalian kringle 5 is disclosed as a compound for treating angiogenic diseases. Methods and compositions for inhibiting angiogenic diseases are also disclosed.
-
公开(公告)号：ES2246513T3
公开(公告)日：2006-02-16
申请号：ES97925478
申请日：1997-05-05
Applicant: ABBOTT LAB
Inventor： DAVIDSON DONALD J , WANG JIEYI , GUBBINS EARL J
IPC: C12N15/09 , A61K20060101 , A61K35/14 , A61K38/00 , A61K38/04 , A61K38/48 , A61K39/00 , A61K45/00 , A61K48/00 , A61K101/00 , A61P1/04 , A61P15/18 , A61P17/06 , A61P19/02 , A61P27/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07K1/00 , C07K14/00 , C07K14/47 , C07K14/515 , C07K19/00 , C12N20060101 , C12N9/68 , C12N15/02 , C12N15/57 , C12P21/06
Abstract: LA INVENCION SE REFIERE A FRAGMENTOS KRINGLE DE MAMIFEROS (5) Y A PROTEINAS DE FUSION KRINGLE (5), COMO COMPUESTOS PARA TRATAR ENFERMEDADES ANGIOGENICAS. SE DESCRIBEN ASIMISMO PROCEDIMIENTOS Y COMPOSICIONES PARA INHIBIR LAS ENFERMEDADES ANGIOGENICAS.
-
Patent Agency Ranking
公开(公告)号：AT299888T
公开(公告)日：2005-08-15
申请号：AT97925478
申请日：1997-05-05
Applicant: ABBOTT LAB
Inventor： DAVIDSON DONALD J , WANG JIEYI , GUBBINS EARL J
IPC: C12N15/09 , A61K20060101 , A61K35/14 , A61K38/00 , A61K38/04 , A61K38/48 , A61K39/00 , A61K45/00 , A61K48/00 , A61K101/00 , A61P1/04 , A61P15/18 , A61P17/06 , A61P19/02 , A61P27/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07K1/00 , C07K14/00 , C07K14/47 , C07K14/515 , C07K19/00 , C12N20060101 , C12N9/68 , C12N15/02 , C12N15/57 , C12P21/06
Abstract: Compounds of formulae (I) and (II), and their salts, esters and prodrugs, are new: A-B-C-X-Y (I); A-B1-C1-X1-Y (II); A = absent or a nitrogen-protecting group; Y = absent or a carboxy-protecting group; B = absent or 1-197 naturally occurring amino acids (aa) corresponding to residues 334-530 of the 791 aa human plasminogen (hPA) sequence given in the specification; C = Lys-R2-R3-Asp; R2 = Leu or Arg; R3 = Tyr, 3-iodotyrosinyl (ITyr) or Phe; X = absent or is 1-12 naturally occurring aa corresponding to residues 535-546 of hP and its homologues or analogues; B1 = absent or is 1-176 aa corresponding to residues 334-513 of hP; C1 = the 514-523 aa sequence of hP; X1 = absent or is 1-10 aa corresponding to residues 524-533 of hP.
-
27.发明专利
公开(公告)号：NZ332319A
公开(公告)日：2000-09-29
申请号：NZ33231997
申请日：1997-05-05
Applicant: ABBOTT LAB
Inventor： DAVIDSON DONALD J , WANG JIEYI , GUBBINS EARL J
IPC: C12N15/09 , A61K20060101 , A61K35/14 , A61K38/00 , A61K38/04 , A61K38/48 , A61K39/00 , A61K45/00 , A61K48/00 , A61K101/00 , A61P1/04 , A61P15/18 , A61P17/06 , A61P19/02 , A61P27/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07K1/00 , C07K14/00 , C07K14/47 , C07K14/515 , C07K19/00 , C12N20060101 , C12N9/68 , C12N15/02 , C12N15/57 , C12P21/06
Abstract: Mammalian kringle (5) fragments of plasminogen and kringle (5) fusion proteins are disclosed as compounds for treating angiogenic diseases. Methods and compositions for inhibiting angiogenic diseases are also disclosed.
-
28.发明专利
公开(公告)号：AU724077B2
公开(公告)日：2000-09-14
申请号：AU3060697
申请日：1997-05-05
Applicant: ABBOTT LAB
Inventor： DAVIDSON DONALD J , WANG JIEYI , GUBBINS EARL J
IPC: C12N15/09 , A61K20060101 , A61K35/14 , A61K38/00 , A61K38/04 , A61K38/48 , A61K39/00 , A61K45/00 , A61K48/00 , A61K101/00 , A61P1/04 , A61P15/18 , A61P17/06 , A61P19/02 , A61P27/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07K1/00 , C07K14/00 , C07K14/47 , C07K14/515 , C07K19/00 , C12N20060101 , C12N9/68 , C12N15/02 , C12N15/57 , C12P21/06
Abstract: Compounds of formulae (I) and (II), and their salts, esters and prodrugs, are new: A-B-C-X-Y (I); A-B1-C1-X1-Y (II); A = absent or a nitrogen-protecting group; Y = absent or a carboxy-protecting group; B = absent or 1-197 naturally occurring amino acids (aa) corresponding to residues 334-530 of the 791 aa human plasminogen (hPA) sequence given in the specification; C = Lys-R2-R3-Asp; R2 = Leu or Arg; R3 = Tyr, 3-iodotyrosinyl (ITyr) or Phe; X = absent or is 1-12 naturally occurring aa corresponding to residues 535-546 of hP and its homologues or analogues; B1 = absent or is 1-176 aa corresponding to residues 334-513 of hP; C1 = the 514-523 aa sequence of hP; X1 = absent or is 1-10 aa corresponding to residues 524-533 of hP.
-
29.发明专利
公开(公告)号：HK1021191A1
公开(公告)日：2000-06-02
申请号：HK99104850
申请日：1999-10-27
Applicant: ABBOTT LAB , CHILDRENS MEDICAL CENTER
Inventor： DAVIDSON DONALD J , WANG JIEYI , GUBBINS EARL J
IPC: C12N15/09 , A61K20060101 , A61K35/14 , A61K38/00 , A61K38/04 , A61K38/48 , A61K39/00 , A61K45/00 , A61K48/00 , A61K101/00 , A61P1/04 , A61P15/18 , A61P17/06 , A61P19/02 , A61P27/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07K1/00 , C07K14/00 , C07K14/47 , C07K14/515 , C07K19/00 , C12N20060101 , C12N9/68 , C12N15/02 , C12N15/57 , C12P21/06 , C07K
Abstract: Compounds of formulae (I) and (II), and their salts, esters and prodrugs, are new: A-B-C-X-Y (I); A-B1-C1-X1-Y (II); A = absent or a nitrogen-protecting group; Y = absent or a carboxy-protecting group; B = absent or 1-197 naturally occurring amino acids (aa) corresponding to residues 334-530 of the 791 aa human plasminogen (hPA) sequence given in the specification; C = Lys-R2-R3-Asp; R2 = Leu or Arg; R3 = Tyr, 3-iodotyrosinyl (ITyr) or Phe; X = absent or is 1-12 naturally occurring aa corresponding to residues 535-546 of hP and its homologues or analogues; B1 = absent or is 1-176 aa corresponding to residues 334-513 of hP; C1 = the 514-523 aa sequence of hP; X1 = absent or is 1-10 aa corresponding to residues 524-533 of hP.
-
公开(公告)号：CA2327185A1
公开(公告)日：1999-10-14
申请号：CA2327185
申请日：1999-04-08
Applicant: ABBOTT LAB
Inventor： SCIOTTI RICHARD J , GUBBINS EARL J , LULY JAY R , ZHOU XUN , TU NOAH P , WIEDEMAN PAUL E , WARRIOR USHA , DJURIC STEVAN W , MADAR DAVID J , BA MAUNG NWE Y , BASHA ANWER , WAGENAAR FRANK L
IPC: C07D231/12 , A61K31/415 , A61K31/4155 , A61K31/42 , A61K31/422 , A61K31/425 , A61K31/433 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/4439 , A61K31/445 , A61K31/454 , A61K31/475 , A61P17/00 , A61P17/06 , A61P29/00 , A61P37/02 , A61P37/06 , A61P37/08 , A61P43/00 , C07D231/14 , C07D231/16 , C07D401/04 , C07D401/10 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/10 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/10 , C07D409/14 , C07D413/10 , C07D413/12 , C07D417/10 , C07D417/12 , C07D417/14 , C07D495/04 , C07D231/00 , C07D333/00
Abstract: Compounds having formula (I) are useful for treating diseases that are prevented by or ameliorated with Interleukin-2, Interleukin-4, or Interleukin5 production inhibitors.
-
-
-
-
-
-
-
-
-
Search Results
32
records
(took 0.021 seconds)
