公开(公告)号：PT1078932E

公开(公告)日：2004-07-30

申请号：PT00115122

申请日：2000-07-12

Applicant: BASF AG

Inventor： ANDREAS BOTTCHER DR ,  BURST WOLFRAM

IPC: C07B61/00 ,  C07H1/00 ,  C07H7/027

公开(公告)号：AU2003270194A8

公开(公告)日：2004-04-08

申请号：AU2003270194

申请日：2003-09-15

Applicant: BASF AG

Inventor： FREY GUNTHER ,  HARMS GUIDO ,  BURST WOLFRAM ,  JANSEN HELMUT

IPC: B01D20060101 ,  B01D3/00 ,  B01D3/10 ,  B01J19/32

公开(公告)号：DE59900446D1

公开(公告)日：2002-01-10

申请号：DE59900446

申请日：1999-03-05

Applicant: BASF AG

Inventor： RUFF DR ,  BURST WOLFRAM ,  KAISER DR ,  STROEZEL MANFRED

IPC: C07C45/72 ,  C07C45/74 ,  C07C49/603

Abstract: 2,5,6-trimethyl-cyclohex-2-en-1-one (I) is prepared by continuously pumping diethylketone (II), crotonaldehyde (III) and an aqueous strong base through a pressure vessel in such a fashion that the reaction temperature is 150-350 degrees C and the average residence time in the pressure vessel is only 0.1 seconds to 20 minutes. Preparation of 2,5,6-trimethyl-cyclohex-2-en-1-one (I) comprises reaction of (i) diethylketone (II) with (ii) crotonaldehyde (III) (or a compound which is converted to (III) under the selected reaction conditions), in the presence of basic agents, at elevated temperatures. Component (ii) (1 mol), component (i) (5-30 mol) and an aqueous solution or suspension of a strong base are pumped continuously, via separate supply points or in the form of a mixture, into an optionally heated pressure vessel which can guarantee intensive mixing. The components are pumped to the vessel in such a fashion that the reaction temperature is 150-350 degrees C and the average residence time in the pressure vessel is only 0.1 seconds to 20 minutes.

公开(公告)号：AU5839101A

公开(公告)日：2001-11-20

申请号：AU5839101

申请日：2001-05-03

Applicant: BASF AG

Inventor： BOETTCHER ANDREAS ,  BURST WOLFRAM

IPC: A61K31/375 ,  A61P3/02 ,  C07B61/00 ,  C07D307/62

Abstract: The invention relates to a process for the preparation of L-ascorbic acid, in which free 2-keto-L-gulonic acid or C3-C10-alkyl 2-keto-L-gulonate is lactonized under acidic conditions in the presence of a water-miscible solvent and where this solvent in situ forms a solvent in which the ascorbic acid formed is poorly soluble.

公开(公告)号：DE10022518A1

公开(公告)日：2001-11-15

申请号：DE10022518

申请日：2000-05-10

Applicant: BASF AG

Inventor： BOETTCHER ANDREAS ,  BURST WOLFRAM

IPC: A61K31/375 ,  A61P3/02 ,  C07B61/00 ,  C07D307/62

Abstract: Preparation of L-ascorbic acids comprises reacting 2-keto-L-gulonic acids or a melt of 2-keto-L-gulonic acid 3-6C alkyl esters under acid catalysis using a water-miscible solvent(s) in with the product is poorly soluble.

公开(公告)号：BR0005323A

公开(公告)日：2001-07-03

申请号：BR0005323

申请日：2000-11-09

Applicant: BASF AG

Inventor： BURST WOLFRAM ,  KAIBEL GERD ,  TTCHER ANDREAS B ,  KESSLER VERONIQUE ,  KUNTZE THOMAS

IPC: B01D3/32 ,  C07B61/00 ,  C07D307/62

Abstract: Continuous production of alkali metal L-ascorbates (I) comprises: a ) esterifying 2-keto-L-gulonic acid or diacetone 2-keto-L-gulonic acid with a C1-C10 alcohol in the presence of an acid catalyst; and (b) rearranging the resulting ester in the presence of an alkali metal C1-C10 alkoxide.

公开(公告)号：DE19903459A1

公开(公告)日：2000-08-03

申请号：DE19903459

申请日：1999-01-28

Applicant: BASF AG

Inventor： STREICHER HARALD ,  BURST WOLFRAM ,  DAEUWEL JUERGEN ,  KOPPENHOEFER JUERGEN

IPC: C07C29/80 ,  C07C31/22 ,  B01D3/14

Abstract: Production of highly pure phytantriol (I) comprises rectification of (I) in a fine vacuum in columns with ordered metal fabric packing and duct distributors with ≥ 500 dripping points/m at an angle of 90 degrees to the layer of fabric just below them. There are 2 or more, 20-100 mm high packing elements with layers of fabric at 90 degrees to one another. Strictly adiabatic rectification with absolute exclusion of air is used. Production of highly pure phytantriol (I) comprises rectification of (I) contaminated with lower and/or higher boiling by-products in a fine vacuum in columns containing metal fabric packing with ordered structure. The liquid is distributed with duct distributors with ≥ 500 dripping points/m . The ducts are at an angle of 90 degrees to the layer of fabric directly below them in the packing. There are 2 or more packing elements with a height of 20-100 mm and layers of fabric at 90 degrees to one another, below the distributor. The process is operated with absolute exclusion of air. Strictly adiabatic rectification is used.

公开(公告)号：CH685476A5

公开(公告)日：1995-07-31

申请号：CH226392

申请日：1992-07-17

Applicant: BASF AG

Inventor： BURST WOLFRAM ,  WINTER MANFRED

IPC: B01F15/06 ,  B01F7/00 ,  B65D6/10

公开(公告)号：DE50112613D1

公开(公告)日：2007-07-26

申请号：DE50112613

申请日：2001-02-23

Applicant: BASF AG

Inventor： BURST WOLFRAM ,  HARTMANN HORST ,  KAIBEL GERD DR ,  HARMS GUIDO DR

IPC: B01D3/14

公开(公告)号：ES2227187T3

公开(公告)日：2005-04-01

申请号：ES01931684

申请日：2001-05-03

Applicant: BASF AG

Inventor： BOETTCHER ANDREAS ,  BURST WOLFRAM

IPC: A61K31/375 ,  A61P3/02 ,  C07B61/00 ,  C07D307/62

Abstract: Procedimiento para la obtención de ácido L- ascórbico, caracterizado porque se lactoniza ácido 2-ceto- L-gulónico, o una fusión de 2-ceto-L-gulonato de alquilo con 3 a 6 átomos de carbono bajo catálisis ácida en presencia de un disolvente exclusivamente, o mezcla de disolventes, que es miscible con agua y forma in situ un disolvente en el que el ácido ascórbico formado tiene una solubilidad de menos de 2 g/l a temperatura ambiente.