公开(公告)号：DK502988A

公开(公告)日：1989-03-11

申请号：DK502988

申请日：1988-09-09

Applicant: BASF AG

Inventor： SCHOLLMEIER KLAUS ,  KREIMEYER ANDREAS ,  DAUM LOTHAR

IPC: A61K38/00 ,  A61P29/00 ,  A61P35/00 ,  A61P43/00 ,  C07K1/22 ,  C07K14/52 ,  C07K14/525 ,  C07K14/555 ,  C07K14/57 ,  C12N15/09 ,  C12P21/02 ,  C12R1/19 ,  C07K13/00 ,  C07H21/04 ,  C07K15/26 ,  C12N15/00

公开(公告)号：FI882283A0

公开(公告)日：1988-05-16

申请号：FI882283

申请日：1988-05-16

Applicant: BASF AG

Inventor： DOERPER THOMAS ,  MOELLER ACHIM ,  HILLEN HEINZ ,  KEILHAUER GERHARD ,  EMLING FRANZ ,  DAUM LOTHAR

IPC: C12N15/09 ,  A61K38/00 ,  A61P35/00 ,  C07K1/20 ,  C07K14/00 ,  C07K14/52 ,  C07K14/525 ,  C07K14/78 ,  C07K19/00 ,  C12P21/02 ,  C12R1/19 ,  C12N

Abstract: Tumor necrosis factor (TNF) produced from the TNF molecule by modification at the amino terminus are prepared as described and are suitable for controlling diseases.

公开(公告)号：DE59007517D1

公开(公告)日：1994-11-24

申请号：DE59007517

申请日：1990-05-04

Applicant: BASF AG

Inventor： LEMAIRE HANS-GEORG ,  HILLEN HEINZ ,  MOELLER ACHIM ,  DAUM LOTHAR ,  DOERPER THOMAS ,  SUBKOWSKI THOMAS

IPC: A61K35/22 ,  A61K38/00 ,  A61K38/17 ,  A61K38/19 ,  A61P7/00 ,  A61P7/02 ,  A61P7/04 ,  A61P11/00 ,  A61P19/00 ,  A61P19/02 ,  A61P19/08 ,  A61P25/00 ,  A61P29/00 ,  A61P31/04 ,  A61P37/00 ,  A61P37/02 ,  A61P37/08 ,  A61P43/00 ,  C07K1/18 ,  C07K1/22 ,  C07K7/08 ,  C07K14/00 ,  C07K14/435 ,  C07K14/47 ,  C07K14/525 ,  C07K14/715 ,  C07K16/18 ,  C07K15/14 ,  A61K35/12

Abstract: PCT No. PCT/EP90/00719 Sec. 371 Date Sep. 26, 1991 Sec. 102(e) Date Sep. 26, 1991 PCT Filed May 4, 1990 PCT Pub. No. WO90/13575 PCT Pub. Date Nov. 15, 1990.Novel proteins which have a molecular weight of about 42,000 daltons and have at the N terminus the amino acid sequence Xaa Thr Pro Tyr Ala Pro Glu Pro Gly Set Thr Cys Arg Leu Arg Glu where X is hydrogen, a phenylalanine residue (Phe) or the amino acid sequences Ala Phe, Val Ala Phe, Gln Val Ala Phe, Ala Gln Val Ala Phe, Pro Ala Gln Val Ala Phe or Leu Pro Ala Gln Val Ala Phe, and which are suitable for the treatment of diseases, are described.

公开(公告)号：HU205385B

公开(公告)日：1992-04-28

申请号：HU242888

申请日：1988-05-16

Applicant: BASF AG

Inventor： DOERPER THOMAS ,  MOELLER ACHIM ,  HILLEN HEINZ ,  KEILHAUER GERHARD ,  EMLING FRANZ ,  DAUM LOTHAR

IPC: C12N15/09 ,  A61K38/00 ,  A61P35/00 ,  C07K1/20 ,  C07K14/00 ,  C07K14/52 ,  C07K14/525 ,  C07K14/78 ,  C07K19/00 ,  C12P21/02 ,  C12R1/19 ,  C12N15/28 ,  C12N15/62

Abstract: Tumor necrosis factor (TNF) produced from the TNF molecule by modification at the amino terminus are prepared as described and are suitable for controlling diseases.

公开(公告)号：CA2050300A1

公开(公告)日：1990-11-10

申请号：CA2050300

申请日：1990-05-04

Applicant: BASF AG

Inventor： HILLEN HEINZ ,  MOELLER ACHIM ,  DOERPER THOMAS ,  DAUM LOTHAR ,  LEMAIRE HANS-GEORG ,  SUBKOWSKI THOMAS

IPC: A61K35/22 ,  A61K38/00 ,  A61K38/17 ,  A61K38/19 ,  A61P7/00 ,  A61P7/02 ,  A61P7/04 ,  A61P11/00 ,  A61P19/00 ,  A61P19/02 ,  A61P19/08 ,  A61P25/00 ,  A61P29/00 ,  A61P31/04 ,  A61P37/00 ,  A61P37/02 ,  A61P37/08 ,  A61P43/00 ,  C07K1/18 ,  C07K1/22 ,  C07K7/08 ,  C07K14/00 ,  C07K14/435 ,  C07K14/47 ,  C07K14/525 ,  C07K14/715 ,  C07K16/18

Abstract: Novel proteins which have a molecular weight of about 42,000 daltons and have at the N terminus the amino acid sequence Xaa Thr Pro Tyr Ala Pro Glu Pro Gly Ser Thr Cys Arg Leu Arg Glu where X is hydrogen, a phenylalanine residue (Phe) or the amino acid sequences Ala Phe, Val Ala Phe, Gln Val Ala Phe, Ala Gln Val Ala Phe, Pro Ala Gln Val Ala Phe or Leu Pro Ala Gln Val Ala Phe, and which are suitable for the treatment of diseases, are described.

公开(公告)号：ZA889699B

公开(公告)日：1990-08-29

申请号：ZA889699

申请日：1988-12-29

Applicant: BASF AG

Inventor： HERR DIETER ,  DIETER HERR ,  DOERPER THOMAS ,  THOMAS DOERPER ,  DAUM LOTHAR ,  LOTHAR DAUM ,  GEISS KARL-HEINZ ,  KARL-HEINZ GEISS ,  MOELLER ACHIM ,  ACHIM MOELLER

IPC: C08B37/10 ,  A61K20060101 ,  A61K31/715 ,  A61P31/12 ,  A61K

公开(公告)号：ZA8809699B

公开(公告)日：1990-08-29

申请号：ZA8809699

申请日：1988-12-29

Applicant: BASF AG

Inventor： HERR DIETER ,  DIETER HERR ,  DOERPER THOMAS ,  THOMAS DOERPER ,  DAUM LOTHAR ,  LOTHAR DAUM ,  GEISS KARL-HEINZ ,  KARL-HEINZ GEISS ,  MOELLER ACHIM ,  ACHIM MOELLER

IPC: C08B37/10 ,  A61K20060101 ,  A61K31/715 ,  A61P31/12 ,  A61K

CPC classification number: A61K31/715

公开(公告)号：CA2005281A1

公开(公告)日：1990-06-12

申请号：CA2005281

申请日：1989-12-12

Applicant: BASF AG

Inventor： BOEHM HANS-JOACHIM ,  DAUM LOTHAR ,  HAUPT ANDREAS ,  SCHMIED BERNHARD ,  WALKER NIGEL ,  ZECHEL JOHANN-CHRISTIAN

IPC: A61K38/00 ,  A61P29/00 ,  A61P35/00 ,  A61P37/06 ,  C07K1/04 ,  C07K7/06 ,  C07K7/08 ,  C07K7/56 ,  C07K7/64 ,  C07K14/52 ,  C07K14/525 ,  A61K38/02 ,  A61K38/08

Abstract: - 33 - O. Z . 0050/40383 Peptides of the formula X-A-Asn-B-Y, where A, B, X and Y are defined in the description, and the preparation thereof are described. The novel peptides are suitable for controlling diseases.

公开(公告)号：CA2005051A1

公开(公告)日：1990-06-12

申请号：CA2005051

申请日：1989-12-11

Applicant: BASF AG

Inventor： BOEHM HANS-JOACHIM ,  DAUM LOTHAR ,  HAUPT ANDREAS ,  SCHMIED BERNHARD ,  WALKER NIGEL ,  ZECHEL JOHANN-CHRISTIAN

IPC: A61K38/00 ,  A61P29/00 ,  A61P35/00 ,  A61P37/06 ,  C07K1/04 ,  C07K7/06 ,  C07K7/08 ,  C07K7/56 ,  C07K7/64 ,  C07K14/52 ,  C07K14/525 ,  A61K38/08 ,  A61K38/10 ,  A61K38/12 ,  A61K38/19 ,  C07K7/50

Abstract: Peptides of the formula X-A-Gly-B-Y, where A, B, X and Y are defined in the description, and the preparation thereof are described. The novel peptides are suitable for controlling diseases.

公开(公告)号：AU3406089A

公开(公告)日：1989-11-09

申请号：AU3406089

申请日：1989-05-05

Applicant: BASF AG

Inventor： DAUM LOTHAR ,  KEILHAUER GERHARD ,  LORENZ GISELA ,  AMMERMANN EBERHARD ,  ANKE TIMM ,  WEBER WOLFGANG ,  STEGLICH WOLFGANG ,  STEFFAN BERT ,  SCHERER ANGELA

IPC: C12P17/18 ,  A01N43/90 ,  A61K31/335 ,  A61P31/04 ,  A61P31/12 ,  A61P35/00 ,  C07D493/10 ,  C12R1/645 ,  C12P17/06

Abstract: Novel strobilurine derivatives which are suitable for the treatment of disorders and as fungicides are described.