公开(公告)号：AU785320B2

公开(公告)日：2007-01-11

申请号：AU5622601

申请日：2001-03-27

Applicant: BASF AG

Inventor： HEIDENFELDER THOMAS ,  WAGENBLAST GERHARD ,  DETERING JURGEN ,  HABECK THORSTEN

IPC: A61Q17/04 ,  C11D3/26 ,  A61K8/40 ,  C09K3/00 ,  C11D3/42 ,  D06L3/12 ,  D06L4/614 ,  D06L4/65 ,  D06L4/657 ,  D06M13/07 ,  D06M13/127 ,  D06M13/152 ,  D06M13/224 ,  D06M13/352 ,  D06M13/358 ,  D06M13/372 ,  D06P1/642 ,  D06P1/651 ,  D06P5/04 ,  D06P5/08

Abstract: A method comprising applying a composition to a textile material with a composition comprising (A) from 10 to 90% by weight of at least one C 6 - to C 18 -alkyl ester or C 5 - to C 8 -cycloalkyl ester of 2-cyano-3,3-diphenylacrylic acid and (B) from 90 to 10% by weight of at least one compound which has at least one UV absorption maximum in the range from 280 nm to 450 nm and is different from compound (A) to thereby obtain an impregnated textile material comprising the composition.

公开(公告)号：ES2252221T3

公开(公告)日：2006-05-16

申请号：ES01929461

申请日：2001-03-27

Applicant: BASF AG

Inventor： HEIDENFELDER THOMAS ,  WAGENBLAST GERHARD ,  DETERING JURGEN ,  HABECK THORSTEN

IPC: C11D3/26 ,  A61K8/40 ,  A61Q17/04 ,  C09K3/00 ,  C11D3/42 ,  D06L3/12 ,  D06L4/614 ,  D06L4/65 ,  D06L4/657 ,  D06M13/07 ,  D06M13/127 ,  D06M13/152 ,  D06M13/224 ,  D06M13/352 ,  D06M13/358 ,  D06M13/372 ,  D06P1/642 ,  D06P1/651 ,  D06P5/04 ,  D06P5/08 ,  A61K7/42 ,  D06M13/402 ,  D06M15/59

Abstract: Empleo de una mezcla constituida por A) desde un 10 hasta un 90 % en peso de al menos un éster de alquilo con 6 hasta 18 átomos de carbono o de un éster de cicloalquilo con 5 hasta 8 átomos de carbono del ácido 2-ciano-3, 3-difenilacrílico y B) desde un 90 hasta un 10 % en peso de al menos otro compuesto, que presente al menos un máximo de absorción de los UV en el intervalo desde 280 hasta 450 nm y que se elige del grupo de los (a) fenilbenzotriazoles, (b) dibenzoilmetanos, (i) diarilbutadienos y (j) hidroxibenzofenonas substituidas por amino como absorbedores de los UV con afinidad para las fibras.

公开(公告)号：ES2228322T3

公开(公告)日：2005-04-16

申请号：ES00105806

申请日：2000-03-18

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  PRECHTL FRANK ,  WUENSCH THOMAS ,  WESTENFELDER HORST ,  HAREMZA SYLKE ,  BACH THORSTEN ,  SPIEGEL ANJA

IPC: C07D295/14 ,  A61K8/00 ,  A61K8/41 ,  A61K8/44 ,  A61K8/49 ,  A61K31/136 ,  A61K31/196 ,  A61K31/24 ,  A61K31/40 ,  A61P17/16 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C225/00 ,  C07C225/22 ,  C07C229/52 ,  C07D295/10 ,  C07D295/112 ,  C09K3/00 ,  A61K7/42

Abstract: Empleo de hidroxibenzofenonas aminosubstituidas de la fórmula general Ib, en la que los substituyentes tienen, independientemente entre sí, el siguiente significado: R1 y R2 significan hidrógeno, alquilo con 1 a 12 átomos de carbono, pudiendo formar los substituyentes R1 y R2 junto con el átomo de nitrógeno, con el que están enlazados, un anillo con 5 o 6 miembros; R5 significa hidrógeno, alquilo con 1 a 12 átomos de carbono, cicloalquilo con 3 a 6 átomos de carbono, como filtros de los UV-A, fotoestables, en preparaciones cosméticas y farmacéuticas para la protección de la piel humana o del cabello humano frente a las irradiaciones solares, solos o junto con compuestos que absorben en el intervalo UV, en sí conocidos, para preparaciones cosméticas y farmacéuticas.

公开(公告)号：ES2186829T3

公开(公告)日：2003-05-16

申请号：ES97113930

申请日：1997-08-13

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  AUMUELLER ALEXANDER ,  SCHEHLMANN VOLKER ,  WESTENFELDER HORST ,  WUENSCH THOMAS

IPC: A61K8/00 ,  A61K8/30 ,  A61K8/40 ,  A61K8/49 ,  A61K8/92 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C255/40 ,  C07D307/52 ,  C07D317/54 ,  C07D333/24 ,  A61K7/42

Abstract: The use of compounds of formula (I) as UV-A filters in cosmetic products (optionally in combination with standard UV absorbers) to protect the human skin against sunlight is claimed. R1-R3 = H or (cyclo)aliphatic group containing up to 18 C, or two of these groups can combine to form a 5 or 6-membered ring ; R4 = optionally substituted (hetero)aryl containing 5-12 ring atoms ; and R5 = R4 or H. Also claimed are (i) cosmetic products containing (I) for protecting the epidermis layer against UV radiation with a wavelength of 280-400 nm and (ii) compounds of formula (II) : R7-R9 = lower alkyl ; R6 = 2-thienyl (optionally substituted with lower alkyl), 4-(3,5-di-t-butyl)-1-hydroxyphenyl or 4-(3,5-di-t-butyl)-1-alkoxyphenyl.

公开(公告)号：AU755281B2

公开(公告)日：2002-12-05

申请号：AU8936798

申请日：1998-10-16

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  WUNSCH THOMAS ,  WESTENFELDER HORST ,  SCHEHLMANN VOLKER ,  HAREMZA SYLKE

IPC: A61K8/00 ,  A61K8/40 ,  A61K31/00 ,  A61P17/00 ,  A61P17/16 ,  A61Q1/04 ,  A61Q17/04 ,  A61K7/42

Abstract: Photo-stable ultraviolet (UV) filters for cosmetic or pharmaceutical use consist of substituted alpha -methyl-styrene derivatives (I). The use of substituted alpha -methyl-styrene derivatives of formula (I), optionally in combination with conventional UV absorbers, as photo-stable UV filters in cosmetic or pharmaceutical preparations for protecting human skin or hair against sunlight is new. R1 = 4-10C alkoxy, 1-12C alkylamino, 1-12C dialkylamino (sic) or a water-solublizing group selected from carboxylate, sulfonate and ammonium residues; R2 = H, 2-10C alkyl or 1-12C alkoxy; R3,R4 = COOR5, COR5, CONR5R6 or CN, R4 and R5 being the same; R5,R6 = H, 1-12C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, aryl or heteroaryl (optionally substituted). Independent claims are given for: (1) the use of (I) as photostable UV-A filters; (2) the use of (I) as UV stabilizers; (3) cosmetic and pharmaceutical compositions for protecting human epidermis or skin against UV light in the 280-400 nm region, comprising a carrier containing (I) (as photostable UV filter) and optionally conventional UV absorbers; (4) (I) for use as medicaments; and (5) pharmaceutical preparations containing (I).

公开(公告)号：AU754785B2

公开(公告)日：2002-11-28

申请号：AU9718198

申请日：1998-12-17

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  HAREMZA SYLKE ,  TRAUTH HUBERT ,  SCHEHLMANN VOLKER ,  WESTENFELDER HORST

IPC: A61K8/49 ,  A61K8/00 ,  A61K31/4035 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07D209/46 ,  C08K5/3417 ,  C08L101/00 ,  C09D7/12 ,  C09K3/00 ,  C09K15/30 ,  C08K5/3447 ,  A61K47/22

Abstract: Use of isoindolinone derivatives of formula (I) as stabilizers for organic materials is new, where: R = H, COOR , COR , CONR R , CN, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, aryl or heteroaryl (optionally substituted); R = COOR , COR , CONR R or CN; or R +R = 7-10C bicycloalkyl or 7-10C bicycloalkenyl; R = H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, 1-12C alkoxy, 1-20C alkoxycarbonyl, 1-12C alkylamino, 1-12C dialkylamino, aryl, heteroaryl (optionally substituted) or a water-solubilizing carboxylate, sulfonate or alkylammonium group; R and R = H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, aryl or heteroaryl (optionally substituted). An Independent claim is included for compounds (I) as medicaments.

公开(公告)号：DE10031809A1

公开(公告)日：2002-01-17

申请号：DE10031809

申请日：2000-07-04

Applicant: BASF AG

Inventor： HAREMZA SYLKE ,  PRECHTL FRANK ,  HABECK THORSTEN

IPC: A61K8/49 ,  A61Q17/00 ,  A61Q17/04 ,  C07D311/22 ,  C07D311/30 ,  C07D405/06 ,  C07D407/06 ,  A61K7/00 ,  A61K7/40

Abstract: Flavonoids (I) are new. Flavonoids of formula (I) are new: [Image] R : (CH=CR4>)nQ; Q : Ar or Het; Ar : phenyl optionally monosubstituted with R3>; R1>H, 1-4C alkyl, OH, 1-4C alkoxy, phenoxy or benzyloxy; R2>H or 1-4C alkyl; R3> = 1-4C alkyl, 1-4C alkoxy or CN; R4>H, 1-4C alkyl or phenyl; n = 0 or 1; Het : pyridyl, furyl or methylpyrrolyl; provided that no more than two of R1>-R3> are H when Q is Ar and n : 0.

公开(公告)号：AU5622601A

公开(公告)日：2001-10-08

申请号：AU5622601

申请日：2001-03-27

Applicant: BASF AG

Inventor： HEIDENFELDER THOMAS ,  WAGENBLAST GERHARD ,  DETERING JURGEN ,  HABECK THORSTEN

IPC: C11D3/26 ,  A61K8/40 ,  A61Q17/04 ,  C09K3/00 ,  C11D3/42 ,  D06L3/12 ,  D06L4/614 ,  D06L4/65 ,  D06L4/657 ,  D06M13/07 ,  D06M13/127 ,  D06M13/152 ,  D06M13/224 ,  D06M13/352 ,  D06M13/358 ,  D06M13/372 ,  D06P1/642 ,  D06P1/651 ,  D06P5/04 ,  D06P5/08 ,  C11D3/00

Abstract: A method comprising applying a composition to a textile material with a composition comprising (A) from 10 to 90% by weight of at least one C 6 - to C 18 -alkyl ester or C 5 - to C 8 -cycloalkyl ester of 2-cyano-3,3-diphenylacrylic acid and (B) from 90 to 10% by weight of at least one compound which has at least one UV absorption maximum in the range from 280 nm to 450 nm and is different from compound (A) to thereby obtain an impregnated textile material comprising the composition.

公开(公告)号：BR9907308A

公开(公告)日：2000-12-19

申请号：BR9907308

申请日：1999-06-04

Applicant: BASF AG

Inventor： SCHUHMACHER PETER ,  SCHNEIDER NORBERT ,  WESTENFELDER HORTS ,  HAREMZA SYLKE ,  HABECK THORSTEN ,  MEYER FRANK

IPC: A61K8/00 ,  A61K8/02 ,  A61K8/23 ,  A61K8/25 ,  A61K8/29 ,  A61K8/31 ,  A61K8/33 ,  A61K8/34 ,  A61K8/36 ,  A61K8/37 ,  A61K8/41 ,  A61K8/46 ,  A61K8/49 ,  A61K8/73 ,  A61K8/86 ,  A61K8/89 ,  A61K8/97 ,  A61K8/98 ,  A61K31/255 ,  A61K31/34 ,  A61P17/16 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q1/10 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/00 ,  C09B67/20 ,  C09C3/08 ,  C09K3/00 ,  A61K7/40

Abstract: Liquid crystal compositions forming a cholesteric phase with a pitch of less than 450 nm, comprising either at least one polymerizable chiral liquid crystal monomer or a mixture of at least one polymerizable achiral liquid crystal monomer and at least one chiral additive, are used as ultraviolet filters for protecting skin or hair against solar radiation. Liquid crystal compositions forming a cholesteric phase with a pitch of less than 450 nm, comprising either: (a) at least one polymerizable chiral liquid crystal monomer of formula (I); or (b) a mixture of at least one polymerizable achiral liquid crystal monomer of formula (II) and at least one chiral additive, are used as ultraviolet (UV) filters in cosmetic and pharmaceutical compositions for protecting human skin or hair against solar radiation: A -A = spacers with a chain length of 1-30C; Y -Y = bonds, O, S, C(O)O, OC(O), CH=CHC(O)O, OC(O)O, C(O)N(R), N(R)C(O), CH2O, OCH2, CH=N, N=CH or N=N; M , M = mesogenic groups; R = H or 1-4C alkyl; Z = H, 1-4C alkyl or a polymerizable group, at least one being a polymerizable group; Z , Z = H, 1-4C alkyl or polymerizable groups, at least one being a polymerizable group; X = an n-valent chiral group; m, o, p = 0 or 1; n = 1-6. Independent claims are also included: (1) use of the liquid crystal compositions as photostable UV reflectors; (2) use of the liquid crystal compositions as UV stabilizers in cosmetic and pharmaceutical formulations; (3) pigments containing the polymerized liquid crystal compositions.

公开(公告)号：DE19926779A1

公开(公告)日：2000-12-14

申请号：DE19926779

申请日：1999-06-11

Applicant: BASF AG

Inventor： PRECHTL FRANZ ,  HABECK THORSTEN ,  WESTENFELDER HORST ,  WUENSCH THOMAS

IPC: A61K8/00 ,  C07D311/58 ,  A61K8/30 ,  A61K8/35 ,  A61K8/368 ,  A61K8/37 ,  A61K8/40 ,  A61K8/49 ,  A61K47/08 ,  A61K47/14 ,  A61K47/16 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C255/34 ,  C07C261/02 ,  C07D311/04 ,  C07D495/04 ,  C08K5/07 ,  C08K5/1545 ,  C08K5/20 ,  C08K5/315 ,  C08K5/3435 ,  C08K5/42 ,  C08L101/00 ,  C09K3/00 ,  C09K15/06 ,  C09K15/16 ,  C09K15/20 ,  C09K15/30 ,  A61K7/40

Abstract: 6-Vinyl-3,4-dihydro-2H-1-benzopyran, 6-vinyl-1,2,3,4-tetrahydronaphthalene or 6-vinyl-1,2,3,4-tetrahydroquinoline derivatives (I) are used as photostable ultraviolet (UV) filters in cosmetic and pharmaceutical compositions for protecting human skin and hair against solar radiation. Compounds of formula (I) are used as photostable UV filters in cosmetic and pharmaceutical compositions for protecting human skin and hair against solar radiation: X = O, CO, optionally substituted imino or CR9R10; Y = CO or CR9R10; R1, R2 = CN, alkanoyl, aroyl, alkoxycarbonyl, aryloxycarbonyl, optionally substituted carbamoyl, alkylsulfinyl, arylsulfinyl, alkylsulfonyl, arylsulfonyl or optionally substituted sulfamoyl; R3 = H, CN, OH, COOH, CONH2, Q, OQ, CONHQ or COOQ; Q = 1-20C alkyl or 5-20C aryl; R4 = H, OH, NH2, Q or OQ; R5-R10 = H or 1-20C alkyl, or R7+R8 can be oxo. Independent claims are also included for the following: (1) use of (I) as photoprotective agents for stabilizing plastics; (2) cosmetic compositions for protecting human epidermis and hair against UV light of wavelength 280-400 nm, comprising (I) in a carrier; and (3) new compounds of formula (II): R3' = lower alkyl; R4' = H, lower alkyl or lower alkoxy; X' = O or CRR; R = H or lower alkyl.