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公开(公告)号:CZ20032468A3
公开(公告)日:2004-03-17
申请号:CZ20032468
申请日:2002-03-15
Applicant: BASF AG
Inventor: HENNINGSEN MICHAEL , KUSCHE ANDREAS , HULLMANN MICHAEL , RUB LOTHAR , KASHAMMER STEFAN , GERLACH TILL
IPC: C07D265/30 , C07B61/00 , C07D295/02 , C07D295/023 , C07D295/03 , C07D295/033 , A01N43/84
Abstract: The present invention relates to a process for the preparation of N-substituted 2,6-dialkylmorpholines of the formula I in which R 1 and R 2 , independently of one another, are hydrogen, alkyl or cycloalkyl, or R 1 and R 2 together with the carbon atom to which they are bonded are a 5- to 14-membered carbocycle, and R 3 and R 4 , independently of one another, are alkyl or cycloalkyl, by reacting at least one carbonyl compound of the formula II in which R 1 and R 2 have the meanings given above, with at least one morpholine of the formula III in which R 3 and R 4 have the meanings given above, in the presence of hydrogen and at least one metal-containing catalyst, wherein the active component of the catalyst consists essentially of platinum group metals.
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公开(公告)号:HU0303478A2
公开(公告)日:2004-03-01
申请号:HU0303478
申请日:2002-03-15
Applicant: BASF AG
Inventor: GERLACH TILL DR , HENNINGSEN MICHAEL , HUELLMANN MICHAEL , KUSCHE ANDREAS , KAESHAMMER STEFAN , RUEB LOTHAR
IPC: C07D265/30 , C07B61/00 , C07D295/02 , C07D295/023 , C07D295/03 , C07D295/033
Abstract: The present invention relates to a process for the preparation of N-substituted 2,6-dialkylmorpholines of the formula I in which R 1 and R 2 , independently of one another, are hydrogen, alkyl or cycloalkyl, or R 1 and R 2 together with the carbon atom to which they are bonded are a 5- to 14-membered carbocycle, and R 3 and R 4 , independently of one another, are alkyl or cycloalkyl, by reacting at least one carbonyl compound of the formula II in which R 1 and R 2 have the meanings given above, with at least one morpholine of the formula III in which R 3 and R 4 have the meanings given above, in the presence of hydrogen and at least one metal-containing catalyst, wherein the active component of the catalyst consists essentially of platinum group metals.
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公开(公告)号:CA2440518A1
公开(公告)日:2002-09-26
申请号:CA2440518
申请日:2002-03-15
Applicant: BASF AG
Inventor: KUSCHE ANDREAS , GERLACH TILL , HULLMANN MICHAEL , HENNINGSEN MICHAEL , RUB LOTHAR , KASHAMMER STEFAN
IPC: C07D265/30 , C07B61/00 , C07D295/02 , C07D295/023 , C07D295/03 , C07D295/033 , A01N43/84
Abstract: The invention relates to a method of producing the N-substituted 2,6-dialkyl morpholines of general formula (I), wherein R1 and R2 independently represen t hydrogen, alkyl or cycloalkyl, or R1 and R2, together with the carbon atom t o which they are bound, represent a 5 to 14 membered carbocyclic compound, and R3 and R4 independently represent alkyl or cycloalkyl. The inventive substances are produced by reacting at least one carbonyl compound of genera l formula (II), wherein R1 and R2 are defined as above, with at least one morpholine of general formula (III), wherein R3 and R4 are defined as above, in the presence of hydrogen and at least one metal-containing catalyst, the active component of said catalyst substantially consisting of platinum group metals.
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