公开(公告)号：CA2208539C

公开(公告)日：2004-04-20

申请号：CA2208539

申请日：1995-12-22

Applicant: BASF AG

Inventor： MAIER WERNER ,  ROSENBERG JOERG ,  FRICKE HELMUT ,  BREITENBACH JORG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

Abstract: the present invention concerns a method of producing divisible tablets by me lt calendering: two form cylinders are combined, one of the cylinders having at least one recess with at least one ridge which extends as far as the surface line of the cylinder and forms a break groove.

公开(公告)号：GR3032913T3

公开(公告)日：2000-07-31

申请号：GR20000400573

申请日：2000-03-09

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  MAIER WERNER ,  GRABOWSKI SVEN ,  BREITENBACH JOERG

IPC: A61J1/03 ,  A61J3/00 ,  A61J3/10 ,  A61K9/20 ,  A61K9/28 ,  B30B11/16 ,  B65B9/04

公开(公告)号：PL178357B1

公开(公告)日：2000-04-28

申请号：PL32087595

申请日：1995-12-22

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  MAIER WERNER ,  FRICKE HELMUT ,  BREITENBACH JOERG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

Abstract: PCT No. PCT/EP95/05117 Sec. 371 Date Jun. 18, 1997 Sec. 102(e) Date Jun. 18, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/19962 PCT Pub. Date Jul. 4, 1996A process for the production of divisible tablets by melt calendering in which two molding rolls are combined together, at least one of which has depressions with at least one bar which extends up to the surface line of the molding roll and forms a score.

公开(公告)号：GR3031015T3

公开(公告)日：1999-12-31

申请号：GR990402093

申请日：1999-08-18

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  MAIER WERNER ,  BREITENBACH JOERG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

Abstract: PCT No. PCT/EP95/05119 Sec. 371 Date Jun. 20, 1997 Sec. 102(e) Date Jun. 20, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/19964 PCT Pub. Date Jul. 4, 1996The present invention relates to a process for the production of lenticular tablets by melt calendering in which molding rolls with depressions in the shape of segments of an ellipsoid are used. The process according to the invention affords tablets which are easily deflashed and in which the tablet residue to be abraded when there is a displacement between the upper and lower half of the tablet is small.

公开(公告)号：NZ298774A

公开(公告)日：1999-07-29

申请号：NZ29877495

申请日：1995-12-22

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  MAIER WERNER ,  BREITENBACH JORG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

Abstract: PCT No. PCT/EP95/05119 Sec. 371 Date Jun. 20, 1997 Sec. 102(e) Date Jun. 20, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/19964 PCT Pub. Date Jul. 4, 1996The present invention relates to a process for the production of lenticular tablets by melt calendering in which molding rolls with depressions in the shape of segments of an ellipsoid are used. The process according to the invention affords tablets which are easily deflashed and in which the tablet residue to be abraded when there is a displacement between the upper and lower half of the tablet is small.

公开(公告)号：CA2312917A1

公开(公告)日：1999-06-17

申请号：CA2312917

申请日：1998-12-09

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  MAIER WERNER ,  TRAPP BURKHARD ,  JOTTER KARL LUDWIG ,  ROSENBERG JOERG ,  KRULL HARALD ,  FARWERCK KARL-PETER ,  LANGE ARMIN ,  KLEINKE ANDREAS ,  JOCHUM ALFONS

IPC: A61K9/16 ,  B01J2/20 ,  B29B9/06 ,  B30B9/28 ,  B30B11/22 ,  C05G3/00

Abstract: The invention relates to an extrusion device, particularly an extrusion device for thermoplastic or dough-like masses or highly tenacious melts, and to the use of said device. The extrusion device has a housing (11), at least one conveyor worm (12) arranged in a housing and an outlet (20) disposed on the front face of the housing (11) close to the end of each conveyor screw which is furthest away from the drive end. At least one stripping member (21) is arranged in between the end (14) of each conveyor screw (12) furthest away from the drive end and the outlet (20). The device is particularly suitable for producing granulates, preferably those containing active substances.

公开(公告)号：DE59503813D1

公开(公告)日：1998-11-05

申请号：DE59503813

申请日：1995-12-22

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  MAIER WERNER ,  FRICKE HELMUT ,  BREITENBACH JOERG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

Abstract: PCT No. PCT/EP95/05117 Sec. 371 Date Jun. 18, 1997 Sec. 102(e) Date Jun. 18, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/19962 PCT Pub. Date Jul. 4, 1996A process for the production of divisible tablets by melt calendering in which two molding rolls are combined together, at least one of which has depressions with at least one bar which extends up to the surface line of the molding roll and forms a score.

公开(公告)号：CZ9701871A3

公开(公告)日：1998-05-13

申请号：CZ187197

申请日：1995-12-22

Applicant: BASF AG

Inventor： ROSENBERG JOERG DR ,  MAIER WERNER ,  FRICKE HELMUT DR ,  BREITENBACH JORG DR

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

CPC classification number: B30B11/165 ,  A61J3/10 ,  A61K9/2072 ,  Y10S53/90

公开(公告)号：SK76997A3

公开(公告)日：1998-02-04

申请号：SK76997

申请日：1995-12-22

Applicant: BASF AG

Inventor： ROSENBERG JORG ,  MAIER WERNER ,  FRICKE HELMUT ,  BREITENBACH JORG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

Abstract: The present invention concerns a method of producing divisible tablets by melting the mixture containing one or more pharmaceutically active substances and one or more additive substances; and by calendering the melting with two rotating form cylinders with the cavities for suppression and forming the melting to the tablets. Device for suppression and forming of the melting to the tablets comprises at least one form cylinder (6, 8) with cavities (2) divided by at least one ridge (7) which extends as far as the surface line of the cylinder and forms a break groove.

公开(公告)号：CZ185297A3

公开(公告)日：1998-01-14

申请号：CZ185297

申请日：1995-12-22

Applicant: BASF AG

Inventor： ROSENBERG JOERG DR ,  MAIER WERNER ,  GRABOWSKI SVEN DR ,  BREITENBACH JORG DR

IPC: A61J1/03 ,  A61J3/00 ,  A61J3/10 ,  A61K9/20 ,  A61K9/28 ,  B30B11/16 ,  B65B9/04