公开(公告)号：ZA200101976B

公开(公告)日：2002-03-11

申请号：ZA200101976

申请日：2001-03-09

Applicant: BASF AG

Inventor： STEINER GERD ,  HOEGER THOMAS ,  UNGER LILIANE ,  TESCHENDORF HANS-JUERGEN ,  JUCHELKA FRIEDER

IPC: A61K31/425 ,  A61K31/428 ,  A61P25/00 ,  C07D417/06 ,  C07D ,  A61K

Abstract: Compounds of the formula I:in which R1, R2, R3 and R4 have the meanings stated in the description, are described.The novel compounds are suitable for controlling diseases.

公开(公告)号：SK9682001A3

公开(公告)日：2002-03-05

申请号：SK9682001

申请日：1999-12-22

Applicant: BASF AG

Inventor： STEINER GERD ,  SCHELLHAAS KURT ,  LUBISCH WILFRIED ,  HOLZENKAMP UTA ,  STARCK DOROTHEA ,  SZABO LASZLO ,  EMLING FRANZ ,  GARCIA-LADONA FRANCISCO JAVIER ,  HOFMANN HANS-PETER ,  UNGER LILIANE

IPC: C07D275/06 ,  A61K31/4439 ,  A61K31/454 ,  A61K31/496 ,  A61K31/502 ,  A61K31/517 ,  A61K31/519 ,  A61K31/522 ,  A61K31/55 ,  A61K31/551 ,  A61P9/10 ,  A61P25/28 ,  C07D401/12 ,  C07D417/12 ,  C07D471/04 ,  A61K31/428

Abstract: The invention relates to the utilisation of compounds of formula (I) wherein the substituents have the meanings given in the description. The invention also relates to the salts thereof comprising pharmacologically compatible acids for producing medicaments for the prophylaxis and therapy of cerebral ischaemia and strokes.

公开(公告)号：ID30022A

公开(公告)日：2001-11-01

申请号：ID20011717

申请日：1999-12-22

Applicant: BASF AG

Inventor： STEINER GERD ,  SCHELLHAAS KURT ,  LUBISCH WILFRIED ,  HOLZENKAMP UTA ,  STARCK DOROTHEA ,  SZABO LASZLO ,  EMLING FRANZ ,  LADONA FRANSISCO JAVIER GARCIA ,  HOFMANN HANS PETER ,  UNGER LILIANE

IPC: C07D495/04 ,  A61K31/505 ,  A61K31/519 ,  A61P9/10 ,  C07D495/14

Abstract: Use of pyrimidine derivatives of the formula Iwhere the substituents are as defined in the description, and of their physiologically tolerated salts for producing medicaments for the prophylaxis and treatment of cerebral ischemia and strokes.

公开(公告)号：HU0101311A2

公开(公告)日：2001-09-28

申请号：HU0101311

申请日：1998-07-23

Applicant: BASF AG

Inventor： BACH ALFRED ,  DULLWEBER UTA ,  EMLING FRANZ ,  GARCIA-LADONA XAVIER ,  STARCK DOROTHEA ,  STEINER GERD ,  TESCHENDORF HANS-JUERGEN ,  WICKE KARSTEN

IPC: A61K31/435 ,  A61P25/24 ,  C07D495/14

Abstract: 3-Substituted 3,4,5,7-tetrahydropyrrolo[3',4':4,5]thieno-[2,3-d]pyrimidine derivatives of the formula Iin which the substituents have the meanings stated in the description, their preparation and their use as drugs.

公开(公告)号：CZ288896B6

公开(公告)日：2001-09-12

申请号：CZ75999

申请日：1997-08-22

Applicant: BASF AG

Inventor： STEINER GERD ,  LUBISCH WILFRIED ,  BACH ALFRED ,  EMLING FRANZ ,  WICKE KARSTEN ,  TESCHENDORF HANS-JURGEN ,  BEHL BERTHOLD ,  CHEETHAM SHARON ,  KERRRIGAN FRANK

IPC: A61K31/435 ,  A61K31/519 ,  A61P25/24 ,  A61P43/00 ,  C07D211/00 ,  C07D239/00 ,  C07D333/00 ,  C07D495/14 ,  A61K31/4365 ,  A61K31/40

Abstract: In the present invention there are disclosed 3-substituted pyrido 3,4,5,6,7,8-hexahydro-pyrido (4 ,3 :4,5)thieno(2,3-d) pyrimidine derivatives of the general formula I, wherein the substituents have specific meanings and their salts with physiologically acceptable acids. These compounds are used for preparing medicaments intended for treating depressions and for inhibiting back absorption of serotonin. They are also used as selective antagonists.

公开(公告)号：HRP931500B1

公开(公告)日：2001-08-31

申请号：HRP931500

申请日：1993-12-16

Applicant: BASF AG

Inventor： STEINER GERD ,  UNGER LILIANE ,  BEHL BERTOLD ,  TESCHENDORF HANS-JUERGEN

IPC: A61K31/40 ,  C07D209/52

公开(公告)号：CZ2001465A3

公开(公告)日：2001-08-15

申请号：CZ2001465

申请日：1999-07-20

Applicant: BASF AG

Inventor： STEINER GERD ,  HOGER THOMAS ,  UNGER LILIANE ,  TESCHENDORF HANS-JURGEN ,  JUCHELKA FRIEDER

IPC: A61K31/4184 ,  A61P25/20 ,  A61P25/24 ,  A61P25/30 ,  C07D403/06

Abstract: The invention relates to compounds of formula (1), wherein R , R and R have the meaning cited in the description. The novel substances are suitable for use in disease control.

公开(公告)号：CZ2001508A3

公开(公告)日：2001-07-11

申请号：CZ2001508

申请日：1999-07-20

Applicant: BASF AG

Inventor： STEINER GERD ,  HOGER THOMAS ,  UNGER LILIANE ,  TESCHENDORF HANS-JUGEN ,  JUCHELKA FRIEDER

IPC: A61K31/427 ,  A61P25/00 ,  C07D417/06

公开(公告)号：BR9914655A

公开(公告)日：2001-07-03

申请号：BR9914655

申请日：1999-10-13

Applicant: BASF AG

Inventor： BISCHOF NORBERT ,  BUSCHMANN ERNST ,  HENNINGSEN MICHAEL ,  KREI GEORGE ARNOLD ,  MUNSCHAUER RAINER ,  PFEIFFER THOMAS ,  STEINER GERD ,  VIERGUTZ WOLFGANG

IPC: C07D209/52 ,  A61K31/40 ,  C07B37/10 ,  C07D20060101

Abstract: A process for preparing (+)-exo-6-phenyl-3-azabicyclo[3.2.0]heptanes of the formula Iwhere R is hydrogen, chlorine, bromine, fluorine or methoxy, which comprises photocyclizing a bisallylammonium salt of the formula IIwhere R has the meanings given above and X- is an anion, in an inert solvent in a glass apparatus with addition of sensitizer and precipitating using (-)-ditoluoyltartaric acid the desired (+)-exo-isomer I as ditoluoyltartrate from the resulting mixture, with or without recrystallization of this tartrate from an alcohol/water mixture.

公开(公告)号：DE19960074A1

公开(公告)日：2001-06-21

申请号：DE19960074

申请日：1999-12-13

Applicant: BASF AG

Inventor： NOLD KARLHEINZ ,  SCHLECKER RAINER ,  STEINER GERD ,  THYES MARCO

IPC: C07D403/06

Abstract: The invention relates to belaperidone fumarate.