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公开(公告)号:AT188485T
公开(公告)日:2000-01-15
申请号:AT95917963
申请日:1995-04-26
Applicant: BASF AG
Inventor: AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANITSCHKE LOTHAR , JANSSEN BERND , KARL ULRICH , KLING ANDREAS , MUELLER STEFAN , DE POTZOLLI BERND , RITTER KURT , THYES MARCO , ZIERKE THOMAS
Abstract: PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.
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公开(公告)号:CZ9900210A3
公开(公告)日:2000-01-12
申请号:CZ21099
申请日:1997-07-14
Applicant: BASF AG
Inventor: MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS , BALKENHOHL FRIEDHELM , LANGE UDO
IPC: C07D207/22
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公开(公告)号:BR9711191A
公开(公告)日:1999-08-17
申请号:BR9711191
申请日:1997-07-29
Applicant: BASF AG
Inventor: BAUCKE DORIT , LANGE UDO , MACK HELMUT , SEITZ WERNER , ZIERKE THOMAS , HOFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K38/00 , A61K38/05 , A61P7/02 , A61P29/00 , A61P35/00 , A61P35/04 , C07K5/06 , C07K5/062 , C07K5/065
Abstract: PCT No. PCT/EP97/04104 Sec. 371 Date Feb. 10, 1999 Sec. 102(e) Date Feb. 10, 1999 PCT Filed Jul. 29, 1997 PCT Pub. No. WO98/06741 PCT Pub. Date Feb. 19, 1998Compounds of the formula where A, B, E and D have the meanings indicated in the description, and their preparation are described. The substances are suitable for controlling diseases.
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公开(公告)号:BR9711134A
公开(公告)日:1999-08-17
申请号:BR9711134
申请日:1997-07-29
Applicant: BASF AG
Inventor: BAUCKE DORIT , LANGE UDO , MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS , HOEFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K31/40 , A61K31/44 , A61K38/00 , A61K38/05 , A61P1/18 , A61P7/02 , A61P11/02 , A61P11/06 , A61P17/00 , A61P19/02 , A61P29/00 , A61P43/00 , C07D207/22 , C07D211/78 , C07K5/00 , C07K5/02 , C07K5/083 , C07D2
Abstract: Compounds of the formula Iwhere R, R1, R2, R3, R4, R5 and R6, and l, m and n have the meanings stated in the description, and their preparation are described. The novel compounds are suitable for controlling diseases.
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公开(公告)号:TR199900310T2
公开(公告)日:1999-04-21
申请号:TR9900310
申请日:1997-07-29
Applicant: BASF AG
Inventor: BAUCKE DORIT , LANGE UDO , MACK HELMUT , SEITZ WERNER , ZIERKE THOMAS , HOEFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K38/00 , A61K38/05 , A61P7/02 , A61P29/00 , A61P35/00 , A61P35/04 , C07K5/06 , C07K5/062 , C07K5/065
Abstract: PCT No. PCT/EP97/04104 Sec. 371 Date Feb. 10, 1999 Sec. 102(e) Date Feb. 10, 1999 PCT Filed Jul. 29, 1997 PCT Pub. No. WO98/06741 PCT Pub. Date Feb. 19, 1998Compounds of the formula where A, B, E and D have the meanings indicated in the description, and their preparation are described. The substances are suitable for controlling diseases.
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公开(公告)号:NO991010D0
公开(公告)日:1999-03-02
申请号:NO991010
申请日:1999-03-02
Applicant: BASF AG
Inventor: SCHOFER BERND , ZIERKE THOMAS
IPC: C07D213/81 , C07B43/00 , C07C257/10 , C07D213/73 , C07D213/78 , C07D271/06 , C07D401/12 , C07D413/12 , C07K1/06 , C07K5/062 , C07D
Abstract: A process for preparing amidines and their salts with inorganic or organic acids comprises reacting the corresponding nitrile with ammonia, C1-C6-alkylamine or hydrazine in the presence of a mercaptocarboxylic acid and in the presence or absence of an in-organic or organic ammonium salt.
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公开(公告)号:ZA977240B
公开(公告)日:1999-02-15
申请号:ZA977240
申请日:1997-08-13
Applicant: BASF AG
Inventor: BAUCKE DORIT , LANGE UDO , MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS , HOEFFKEN HANS WOLFGANG , HORNBERGER WILFRIED
IPC: A61K31/40 , A61K31/44 , A61K38/00 , A61K38/05 , A61P1/18 , A61P7/02 , A61P11/02 , A61P11/06 , A61P17/00 , A61P19/02 , A61P29/00 , A61P43/00 , C07D207/22 , C07D211/78 , C07K5/00 , C07K5/02 , C07K5/083 , C07K , A61K , C07D
Abstract: Compounds of the formula Iwhere R, R1, R2, R3, R4, R5 and R6, and l, m and n have the meanings stated in the description, and their preparation are described. The novel compounds are suitable for controlling diseases.
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公开(公告)号:SK76798A3
公开(公告)日:1999-02-11
申请号:SK76798
申请日:1996-12-11
Applicant: BASF AG
Inventor: AMBERG WILHELM , BARLOZZARI TERESA , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , HEGE HANS-GUENTHER , JANSSEN BERND , KLING ANDREAS , LIETZ HELMUT , RITTER KURT , ULLRICH MARTINA , WEYMANN JURGEN , ZIERKE THOMAS
Abstract: Novel peptides of the formula R R N-CHX-CO-A-B-D-E-(G)s-K in which R , R , A, B, D, E, G, K, X, and s have the meanings stated in the description, and the preparation thereof are described. The novel peptides have an antineoplastic effect.
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公开(公告)号:DE59504450D1
公开(公告)日:1999-01-14
申请号:DE59504450
申请日:1995-04-26
Applicant: BASF AG
Inventor: AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANITSCHKE LOTHAR , JANSSEN BERND , KARL ULRICH , KLING ANDREAS , MUELLER STEFAN , DE POTZOLLI BERND , RITTER KURT , THYES MARCO , ZIERKE THOMAS
Abstract: Compounds of the formulawhere R1, R2, R3 and R4 have the meaning stated in the description, and a process for preparing them are described. The compounds are suitable as starting material for synthesizing substances which are active against tumors.
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公开(公告)号:PL327175A1
公开(公告)日:1998-11-23
申请号:PL32717596
申请日:1996-12-11
Applicant: BASF AG
Inventor: AMBERG WILHELM , BARLOZZARI TERESA , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , HEGE HANS-GUENTHER , JANSSEN BERND , KLING ANDREAS , LIETZ HELMUT , RITTER KURT , ULLRICH MARTINA , WEYMANN JUERGEN , ZIERKE THOMAS
Abstract: Novel peptides of the formula R R N-CHX-CO-A-B-D-E-(G)s-K in which R , R , A, B, D, E, G, K, X, and s have the meanings stated in the description, and the preparation thereof are described. The novel peptides have an antineoplastic effect.
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