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公开(公告)号:AT527337T
公开(公告)日:2011-10-15
申请号:AT03815074
申请日:2003-12-24
Applicant: BASF SE
Inventor: ZELINSKI THOMAS , KESSELER MARIA , HAUER BERNHARD
Abstract: The invention relates to a method for preserving and/or storing microorganisms which exhibit at least one nitrile hydratase or nitrilase enzyme activity, with the preservation and/or storage being effected in an aqueous medium which comprises at least one aldehyde, with the total aldehyde concentration being in a range from 0.1 to 100 mM/l.
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公开(公告)号:ES2357115T3
公开(公告)日:2011-04-18
申请号:ES04765718
申请日:2004-09-30
Applicant: BASF SE
Inventor: STUERMER RAINER , KESSELER MARIA , HAUER BERNHARD , FRIEDRICH THOMAS , BREUER MICHAEL
IPC: C07D333/16 , C07D333/20 , C12N9/04 , C12N15/53 , C12N15/63 , C12P7/04
Abstract: Método para la producción de (S)-3-metilamino-1-(tien-2-il)-propan-1-ol de la fórmula I-S en el cual a) reacciona tiofeno con un halogenuro de ß-halopropionilo o un halogenuro de acriloilo en presencia de un ácido Lewis para dar una 3-halo-1-(tien-2-il)-propan-1-ona, donde se introduce un haluro de hidrógeno simultáneamente o después de terminada la reacción, aunque antes del aislamiento del producto de reacción, y b) se reduce la propanona obtenida en la etapa a) en presencia de una deshidrogenasa (E.C. 1.1.x.x.), la cual exhibe una selectividad respecto a la formación de (S)-3-metilamino-1-(tien-2-il)propan-1-ol, y a continuación, dado el caso, se hace reaccionar con metilamina sin aislamiento del producto de reacción.
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公开(公告)号:DE602007008840D1
公开(公告)日:2010-10-14
申请号:DE602007008840
申请日:2007-01-31
Applicant: BASF SE
Inventor: HAUER BERNHARD , STUERMER RAINER , NESTL BETTINA M , KROUTIL WOLFGANG , FABER KURT
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公开(公告)号:ES2337393T3
公开(公告)日:2010-04-23
申请号:ES06708599
申请日:2006-03-02
Applicant: BASF SE
Inventor: HARING DIETMAR , HAUER BERNHARD , PFEIFFER THOMAS , FECHTENKOTTER ANDREAS , LARBIG HARALD , BECK ERICH
IPC: C08F8/14 , C08F210/02 , C08F216/14 , C08F220/28 , C08F255/02 , C09D11/02 , C09D133/08 , C09K23/52 , C14C9/00 , D06M15/21
Abstract: Método para la producción de ceras de poliolefina que tienen (met)acrilato, que contienen como componentes estructurales formales copolimerizados a)75 a 99,9% molar de por lo menos una α-olefina de la fórmula (I), R1-CH=CH2, donde R1 significa hidrógeno o dado el caso alquilo C1-C18 interrumpido por uno o varios átomos de oxígeno y/o azufre y/o uno o varios grupos imino sustituidos o no sustituidos, b1)0,1 a 15% molar de por lo menos un (met)acrilato de alqueniloxialquilo y/o (met)acrilato de aliloxialquilo y/o b2)0,1 a 25% molar de por lo menos un (met)acrilato de (met)acriloiloxialquilo y/o metacrilamida de (met)acriloiloxialquilo así como c)dado el caso 0 a 25% molar de por lo menos uno monómero diferente de a), b1) y b2) que porta por lo menos un grupo funcional, en cada caso en forma copolimerizada, que abarca las siguientes etapas: (1)producción de una cera de poliolefina mediante copolimerización de A)por lo menos una olefina de la fórmula (I), B1)por lo menos un hidroxialquilalqueniléter y/o hidroxialquilaliléter y/o B2)por lo menos un (met)acrilato de hidroxialquilo y/o hidroxialquil (met)acrilamida así como C)dado el caso por lo menos un monómero diferente de A), B1) y B2) que porta por lo menos un grupo funcional, (2)dado el caso purificación de la cera de poliolefina obtenida, (3)esterificación de la cera de poliolefina obtenida en (1) o (2) con ácido (met)acrílico y/o transesterificación con ésteres de ácido metacrílico, (4)dado el caso, purificación de la cera de poliolefina que tiene metacrilato obtenida, caracterizado porque la esterificación o transesterificación es ejecutada en presencia de por lo menos un enzima.
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公开(公告)号:AT459723T
公开(公告)日:2010-03-15
申请号:AT07822458
申请日:2007-11-09
Applicant: BASF SE
Inventor: BREUER MICHAEL , ERNST HANSGEORG , HAUER BERNHARD
Abstract: The present invention relates to a method for preparing optically active (4S)-4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-one derivatives of the formula (I) and a method for preparing (3S,3'S)-astaxanthin of the formula (III) comprising the first-mentioned method.
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公开(公告)号:AT451452T
公开(公告)日:2009-12-15
申请号:AT07803080
申请日:2007-08-30
Applicant: BASF SE
Inventor: STUERMER RAINER , HAUER BERNHARD , ROSCHE BETTINA , MUELLER ANDRE
Abstract: Producing alkenones (I) comprises reducing an alkynone (II) in the presence of an Old Yellow Enzyme having one of six amino acid sequences given in the specification. Producing alkenones of formula (I) comprises reducing an alkynone of formula (II) in the presence of an Old Yellow Enzyme having one of six amino acid sequences given in the specification. R 1>-CH=CH-CO-R 2> (I) R 1>-CC-CO-R 2> (II) R 1>H, 1-6C alkyl, 2-6C alkenyl or an optionally substituted carbocyclic or heterocyclic aromatic or nonaromatic group; R 2>H, 1-6C alkyl or 2-6C alkenyl.
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公开(公告)号:DE50115182D1
公开(公告)日:2009-11-26
申请号:DE50115182
申请日:2001-08-30
Applicant: BASF SE
Inventor: HAUER BERNHARD , FRIEDRICH THOMAS , NUEBLING CHRISTOPH , STUERMER RAINER , LADNER WOLFGANG
IPC: C12N15/09 , C12N15/55 , C12N1/15 , C12N1/19 , C12N1/20 , C12N1/21 , C12N5/10 , C12N9/16 , C12N9/18 , C12N15/63 , C12P7/00 , C12P7/62 , C12P41/00 , C12R1/38
Abstract: The invention relates to novel proteins from Pseudomonas glumae, having esterase activity, in particular butynol I esterase activity, to nucleic acid sequences coding therefore, to expression cassettes, vectors and recombinant microorganisms; to methods for preparing said proteins and to the use thereof for enzymic, in particular enantioselective enzymic, ester hydrolysis or transesterification of organic esters.
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公开(公告)号:AT445702T
公开(公告)日:2009-10-15
申请号:AT01962989
申请日:2001-08-30
Applicant: BASF SE
Inventor: HAUER BERNHARD , FRIEDRICH THOMAS , NUEBLING CHRISTOPH , STUERMER RAINER , LADNER WOLFGANG
IPC: C12N15/09 , C12N15/55 , C12N1/15 , C12N1/19 , C12N1/20 , C12N1/21 , C12N5/10 , C12N9/16 , C12N9/18 , C12N15/63 , C12P7/00 , C12P7/62 , C12P41/00 , C12R1/38
Abstract: The invention relates to novel proteins from Pseudomonas glumae, having esterase activity, in particular butynol I esterase activity, to nucleic acid sequences coding therefore, to expression cassettes, vectors and recombinant microorganisms; to methods for preparing said proteins and to the use thereof for enzymic, in particular enantioselective enzymic, ester hydrolysis or transesterification of organic esters.
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公开(公告)号:AT435278T
公开(公告)日:2009-07-15
申请号:AT04713882
申请日:2004-02-24
Applicant: BASF SE
Inventor: ZELINSKI THOMAS , KESSELER MARIA , HAUER BERNHARD , FRIEDRICH THOMAS
Abstract: The present Invention relates to new nitrilases with modified Substrate acceptance, the method to obtain them and the use of the aforesaid nitrilases. Said nitrilases are encoded by a polypeptide sequence, which at a Position corresponding to Position 296 in wild-type Alcaligenes faecalis comprises an amino acid which is not tyrosine. The Invention further relates to nucleic acid sequences and amino acid sequences encoding Said nitrilases, expression constructs comprising Said nucleic acid sequences, vectors comprising the nucleic acid sequences or the exPression constructs, to organisms, preferably microorganisms, comprising the nucleic acid sequences, expression constructs or vectors. The Invention additionally relates to a method for preparing carboxylic acids, preferably substituted chiral carboxylic acids from racemic nitriles.
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公开(公告)号:DK1893755T3
公开(公告)日:2009-04-20
申请号:DK06754335
申请日:2006-06-13
Applicant: BASF SE
Inventor: BESELIN ANKE , ROSENAU FRANK , HAUER BERNHARD , JAEGER KARL-ERICH , BREUER MICHAEL
IPC: C12N9/52
Abstract: The invention relates to novel proteins, especially with protease activity, which promote the production of extracellular lipases by bacteria, especially of the genus Burkholderia, nucleic acid sequences encoding them, expression constructs containing them, hosts transformed with them, methods for the production of the proteins with protease activity and methods for the production of lipases, especially by bacteria of the genus Burkholderia.
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