-
公开(公告)号：AU2020201380A1
公开(公告)日：2020-03-12
申请号：AU2020201380
申请日：2020-02-25
Applicant: PTC THERAPEUTICS INC
Inventor： BABU SURESH , BHATTACHARYYA ANURADHA , HWANG SEONGWOO , JANI MINAKSHI , MOON YOUNG-CHOON , SYDORENKO NADIYA
IPC: C07D405/12 , A61K31/506 , A61P25/00
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. N-N (I) In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
-
公开(公告)号：ES2624610T3
公开(公告)日：2017-07-17
申请号：ES14188816
申请日：2004-04-09
Applicant: PTC THERAPEUTICS INC
Inventor： KARP GARY , HWANG SEONGWOO , CHEN GUANGMING , ALMSTEAD NEIL , MOON YOUNG-CHOON
IPC: C07D271/06 , A61K31/4245 , A61P35/00 , C07D271/12 , C07D413/04 , C07D413/10
Abstract: Un compuesto ácido 3-[5-(2-fluoro-fenil)-[1,2,4]oxadiazol-3-il]-benzoico, que tiene la estructura:**Fórmula** o una sal farmacéuticamente aceptable del mismo.
-
公开(公告)号：CY1115870T1
公开(公告)日：2016-06-22
申请号：CY151100039
申请日：2015-01-16
Applicant: PTC THERAPEUTICS INC
Inventor： KARP GARY MITCHELL , HWANG SEONGWOO , CHEN GUANGMING , ALMSTEAD NEIL GREGORY , MOON YOUNG-CHOON
IPC: C07D271/06 , A61K31/4245 , A61P35/00 , C07D271/12 , C07D413/04 , C07D413/10
Abstract: Αποκαλύπτονταινέεςενώσεις 1,2,4-οξαδιάζολοβενζοϊκούοξέος, μέθοδοιχρήσηςκαιφαρμακευτικέςσυνθέσειςπουπεριλαμβάνουνπαράγωγο 1,2,4-οξαδιάζολοβενζοϊκούοξέος. Οιμέθοδοιπεριλαμβάνουνμεθόδουςθεραπείαςή πρόληψηςμίαςνόσουπουβελτιώνεταιμερύθμισηπρόωρουτερματισμούμετάφρασηςή μηνοηματικά-προκαλούμενηςαποσύνθεσης mRNA ήβελτίωσηενόςή περισσότερωνσυμπτωμάτωνπουσυνδυάζονταιμεαυτά.
-
公开(公告)号：PL1737461T3
公开(公告)日：2013-05-31
申请号：PL05725560
申请日：2005-03-15
Applicant: PTC THERAPEUTICS INC
Inventor： MOON YOUNG-CHOON , CAO LIANGXIAN , TAMILARASU NADARAJAN , QI HONGYAN , CHOI SOONGYU , LENNOX WILLIAM JOSEPH , CORSON DONALD THOMAS , HWANG SEONGWOO
IPC: A61K31/497 , A61K31/437 , A61K31/4745 , A61K31/506 , A61K31/5355 , A61K31/541 , A61K31/551 , A61K31/724 , A61P35/00 , C07D471/04
-
公开(公告)号：DK1737461T3
公开(公告)日：2013-03-18
申请号：DK05725560
申请日：2005-03-15
Applicant: PTC THERAPEUTICS INC
Inventor： MOON YOUNG-CHOON , CAO LIANGXIAN , TAMILARASU NADARAJAN , QI HONGYAN , CHOI SOONGYU , LENNOX WILLIAM JOSEPH , CORSON DONALD THOMAS , HWANG SEONGWOO
IPC: A61K31/497 , A61K31/437 , A61K31/4745 , A61K31/506 , A61K31/5355 , A61K31/541 , A61K31/551 , A61K31/724 , A61P35/00 , C07D471/04
-
Patent Agency Ranking
公开(公告)号：NO332843B1
公开(公告)日：2013-01-21
申请号：NO20055314
申请日：2005-11-10
Applicant: PTC THERAPEUTICS INC
Inventor： KARP GARY MITCHELL , HWANG SEONGWOO , CHEN GUANGMING , ALMSTEAD NEIL GREGORY , MOON YOUNG-CHOON
IPC: C07D271/06 , A61K31/4245 , C07D271/12 , C07D413/04 , C07D413/06 , C07D413/10
Abstract: Provided herein is a compound of formulaor a pharmaceutically acceptable salt thereof for use in a method for treating a lysosomal storage disorder associated with a premature stop codon in a patient.
-
公开(公告)号：SG184755A1
公开(公告)日：2012-10-30
申请号：SG2012068193
申请日：2005-03-15
Applicant: PTC THERAPEUTICS INC
Inventor： MOON YOUNG-CHOON , CAO LIANGXIAN , TAMILARASU NADARAJAN , QI HONGYAN , CHOI SOONGYU , LENNOX WILLIAM JOSEPH , CORSON DONALD THOMAS , HWANG SEONGWOO
IPC: A61K31/437 , A61K31/4745 , A61K31/497 , A61K31/506 , A61K31/5355 , A61K31/541 , A61K31/551 , A61K31/724 , C07D471/04
Abstract: In accordance with the present invention, compounds that inhibit the expression of VEGF post-transcriptionally have been identified, and methods for their use provided. In one aspect of the invention, compounds useful in the inhibition of VEGF production, in the inhibition of angiogenesis, and/or in the treatment of cancer, diabetic retinopathy or exudative macular degeneration are provided. In another aspect of the invention, methods are provided for the inhibition of VEGF production, the inhibition of angiogenesis, and/or the treatment of cancer, diabetic retinopathy or exudative macular degeneration using the compounds of the invention. No suitable figure
-
公开(公告)号：EA016575B1
公开(公告)日：2012-06-29
申请号：EA200601697
申请日：2005-03-15
Applicant: PTC THERAPEUTICS INC
Inventor： MOON YOUNG-CHOON , CAO LIANGXIAN , TAMILARASU NADARAJAN , QI HONGYAN , CHOI SOONGYYU , LENNOX WILLIAM JOSEPH , CORSON DONALD THOMAS , HWANG SEONGWOO
IPC: A61K31/497 , A61K31/437 , A61K31/4745 , A61K31/506 , A61K31/5355 , A61K31/541 , A61K31/551 , A61K31/724 , A61P35/00 , C07D471/04
Abstract: Всоответствиис настоящимизобретениембылиидентифицированысоединенияобщейформулы IV, которыепосттранскрипционноингибируютэкспрессию VEGF. Изобретениеотноситсяк соединениям, которыеявляютсяполезнымив ингибированиипродуцирования VEGF, вингибированииангиогенезаи/илив лечениирака, диабетическойретинопатииилиэкссудативнойдегенерациижелтогопятна.
-
公开(公告)号：AU2004229487B9
公开(公告)日：2010-06-10
申请号：AU2004229487
申请日：2004-04-09
Applicant: PTC THERAPEUTICS INC
Inventor： CHEN GUANGMING , KARP GARY MITCHELL , MOON YOUNG-CHOON , HWANG SEONGWOO , ALMSTEAD NEIL GREGORY
IPC: C07D271/06 , A61K31/4245 , C07D271/12 , C07D413/04 , C07D413/10
Abstract: Provided herein is a compound of formulaor a pharmaceutically acceptable salt thereof for use in a method for treating a lysosomal storage disorder associated with a premature stop codon in a patient.
-
公开(公告)号：AU2007235524A1
公开(公告)日：2007-10-18
申请号：AU2007235524
申请日：2007-03-29
Applicant: PTC THERAPEUTICS INC
Inventor： HIRAWAT SAMIT , HWANG SEONGWOO , KARP GARY M , TAKASUGI JEMES J , MILLER LANGDON , WILDE RICHARD G , CHEN GUANGMING , REN HONGYU , MOON YOUNG-CHOON , ALMSTEAD NEIL G , WELCH ELLEN M
-
-
-
-
-
-
-
-
-
Search Results
121
records
(took 0.024 seconds)
