公开(公告)号：KR100884059B1

公开(公告)日：2009-02-19

申请号：KR1020070052619

申请日：2007-05-30

Applicant: 강릉원주대학교산학협력단

Inventor： 임미진 ,  김옥선 ,  김광우 ,  김정식 ,  김혜경 ,  안효영 ,  허길원 ,  조순영 ,  최종원

IPC: A61K36/03 ,  A61P39/06 ,  A61P9/10

Abstract: 본 발명은 항산화 및 항동맥경화 활성을 갖는 다시마 분말 또는 알긴산이 제거된 이의 추출물을 유효성분으로 함유하는 조성물에 관한 것으로서, 상세하게는 본 발명의 다시마 분말 또는 이의 추출물은 고지혈증 또는 동맥경화증을 유도한 동물모델에서 간의 지질과산화 정도를 유의적으로 감소시키고, 혈장의 총 콜레스테롤, 트리글리세라이드, HDL-C의 함량을 유의적으로 감소시킴으로써, 고지방식이 섭취에 따른 산화적 스트레스 및 동맥경화와 고지혈증을 방어하는 효과가 있으므로, 이를 포함하는 조성물은 산화적 스트레스 및 콜레스테롤 증가로 인한 질환의 예방 및 치료를 위한 약학조성물 및 건강기능식품으로 유용하게 이용될 수 있다.
다시마 분말, 알긴산이 제거된 추출물, 항산화, 항동맥경화

公开(公告)号：KR1020080105263A

公开(公告)日：2008-12-04

申请号：KR1020070052619

申请日：2007-05-30

Applicant: 강릉원주대학교산학협력단

Inventor： 임미진 ,  김옥선 ,  김광우 ,  김정식 ,  김혜경 ,  안효영 ,  허길원 ,  조순영 ,  최종원

IPC: A61K36/03 ,  A61P39/06 ,  A61P9/10

Abstract: A pharmaceutical composition, and a health food are provided to treat and prevent the aging and adult disease by the increase of oxidative stress and cholesterol. A pharmaceutical composition comprises a kelp powder having an antioxidizing activity and an activity of the anti-sclerosis of the arteries, or its extract as an effective ingredient. Preferably the kelp powder comprises a powder where alginic acid is removed or a powder where alginic acid is not removed. The extract is obtained by using a solvent selected from C1-C4 low molecular weight alcohols or their mixture solvent.

Abstract translation: 提供药物组合物和保健食品以通过氧化应激和胆固醇的增加来治疗和预防老化和成年疾病。 药物组合物包含具有抗氧化活性和动脉抗硬化活性的海藻粉或其提取物作为有效成分。 海藻粉最好包括去除海藻酸的粉末或不去除海藻酸的粉末。 通过使用选自C1-C4低分子量醇或其混合溶剂的溶剂获得提取物。

公开(公告)号：KR100979889B1

公开(公告)日：2010-09-02

申请号：KR1020080015133

申请日：2008-02-20

Applicant: 강릉원주대학교산학협력단

Inventor： 이기세 ,  김광우 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P3/06

Abstract: 본 발명은 우렁쉥이 (
Halocynthia

roretzi )의 건조분말 또는 추출물을 유효성분으로 함유하는 고지혈증의 예방 및 치료용 조성물에 관한 것으로, 상세하게는 본 발명의 우렁쉥이의 건조분말 또는 추출물은 고지혈증 동물모델의 혈중 지질함량을 유의적으로 감소시킴으로써 항고지혈증 효과를 나타내므로, 상기 조성물은 고지혈증의 예방 및 치료용 약학조성물 또는 건강기능식품으로 유용하게 이용할 수 있다.
우렁쉥이, 고지혈증, 콜레스테롤, 트리톤 WR-1339, 폴록사머-407

公开(公告)号：KR1020100006604A

公开(公告)日：2010-01-21

申请号：KR1020080066788

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  권세은 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P29/00

Abstract: PURPOSE: A composition containing dried powder or its fraction of sand lance fraction is provided to suppress inflammation in an animal model insuding serotonin, carrageenin, and FCA(freund's complete adjuvant). CONSTITUTION: A pharmaceutical composition for preventing and treating inflammation contains dried powder or its fraction of sand lance fraction as an active ingredient. The sand lance is from near East sea, Japan, Sakhalin island, and Okhotsk Sea or Pacific and Atlantic. The pharmaceutical composition is used in the form of powder, granule, tablet, capsule, suspension, syrup, suppository, or sterilization injection solution.

Abstract translation: 目的：提供含有干燥粉末或其部分的喷沙部分的组合物，以抑制血清素，角叉菜胶和FCA（弗氏完全佐剂）的动物模型中的炎症。 构成：用于预防和治疗炎症的药物组合物含有干粉或其作为活性成分的沙枪级分。 沙枪来自东海，日本，萨哈林岛，鄂霍次克海，太平洋和大西洋。 药物组合物以粉末，颗粒剂，片剂，胶囊，悬浮液，糖浆剂，栓剂或灭菌注射液的形式使用。

公开(公告)号：KR1020100006603A

公开(公告)日：2010-01-21

申请号：KR1020080066787

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  권세은 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P19/02

Abstract: PURPOSE: A composition containing dried powder or extract of sand lance fraction is provided to suppress inflammation in animal model and ensure high suppression effect for arthritis in CRP(C-reactive protein) test. CONSTITUTION: A pharmaceutical composition for preventing and treating arthritis contains dried powder or its extract of sand lance fraction as an active ingredient. A method for producing the dried powder of sand lance fraction comprises: a step of washing sand lance to remove foreign materials and salt; a step of cutting the sand lance to skin, intestines, eggs, head, fin, fish bone, cartilage, muscle, eye and gill; and a step of drying through freezing and under the sun.

Abstract translation: 目的：提供含有干粉或沙矛提取物的组合物，以抑制动物模型中的炎症，并确保CRP（C反应蛋白）测试中关节炎的高抑制作用。 构成：用于预防和治疗关节炎的药物组合物含有干燥粉末或其作为活性成分的沙枪部分提取物。 一种生产干燥喷砂干燥粉末的方法，包括：清洗喷砂以除去异物和盐的步骤; 将沙枪切割成皮肤，肠，蛋，头，鳍，鱼骨，软骨，肌肉，眼睛和鳃的一个步骤; 以及通过冷冻和在阳光下干燥的步骤。

公开(公告)号：KR1020090089955A

公开(公告)日：2009-08-25

申请号：KR1020080015136

申请日：2008-02-20

Applicant: 강릉원주대학교산학협력단

Inventor： 이기세 ,  김광우 ,  김옥선 ,  조순영

IPC: A61K35/616 ,  A61K9/14 ,  A23L33/00

CPC classification number: A61K35/616 ,  A23L33/00 ,  A61K9/14

Abstract: A composition for preventing and treating hyperlipidemia is provided to reduce cholesterol and neutral lipid in serum using dried powder or extract of Stichpus japonicas. A pharmaceutical composition for preventing and treating hyperlipidemia comprises dried powder or extract of Stichpus japonicas as an active ingredient. The extract is obtained by using water, low alcohol of 1-4 carbon atoms or their mixture solvent. The dried powder or extract of Stichpus japonicas is contained in the ratio of 0.1-50 weight% based on total weight.

Abstract translation: 提供了一种用于预防和治疗高脂血症的组合物，用于使用干粉或Stichapus japonicas的提取物来降低血清中的胆固醇和中性脂质。 用于预防和治疗高脂血症的药物组合物包括作为活性成分的干燥粉末或蓟马提取物。 通过使用1-4个碳原子的低级醇或其混合溶剂获得提取物。 St The的干燥粉末或提取物的含量占总重量的0.1-50重量％。

公开(公告)号：KR1020090083118A

公开(公告)日：2009-08-03

申请号：KR1020080009094

申请日：2008-01-29

Applicant: 강릉원주대학교산학협력단

Inventor： 김광우 ,  어명희 ,  김옥선 ,  조순영

IPC: A23L1/325 ,  A23L1/326 ,  A23L1/076 ,  A23L1/212

CPC classification number: A23L17/00 ,  A23L3/00 ,  A23L17/10 ,  A23L19/00 ,  A23L21/20

Abstract: A method for preparing fried fish paste using Hypoptychus dybowskii, propolis and sweet pumpkin is provided to prevent acidification, to show excellent taste, flavor, color and texture and to extend the shelf life. A method for preparing fried fish paste comprise the following steps of: removing the internal organs from Hypoptychus dybowskii; successively adding salt, starch, strong flour, medium flour, finely chopped garlic and ginger powder while cutting Hypoptychus dybowskii and putting propolis, sweet pumpkin powder and ice water to the mixture; mixing up the mixture for 1-60 minutes; molding the dough to a predetermined size; frying the moldings in a soybean oil of 100-200‹C for 30-600 seconds; cooling off the fried fish paste down to 15-20‹C and vacuum-packaging it; and keeping the product at 2-7‹C. The mixing ratio of Hypoptychus dybowskii, propolis, sweet pumpkin powder, salt and starch is 50-95.5 : 0.1-1 : 0.1-10 : 0.1-2 : 1-10.

Abstract translation: 提供了一种使用小us i，蜂胶和甜瓜制备油炸鱼酱的方法，以防止酸化，显示出优异的味道，风味，颜色和质感，延长保质期。 一种油炸鱼酱制备方法，包括以下步骤：从o：：：除去内脏; 连续加入盐，淀粉，强面粉，中等面粉，切碎的大蒜和姜粉，同时切割小us us，将蜂胶，甜南瓜粉和冰水倒入混合物中; 混合混合物1-60分钟; 将面团成型为预定尺寸; 在100-200℃的大豆油中煎炸30-600秒; 将炸鱼酱冷却至15-20℃，真空包装; 并将产品保持在2-7℃。 低us bow，蜂胶，甜南瓜粉，盐，淀粉的混合比为50-95.5：0.1-1：0.1-10：0.1-2：1-10。

公开(公告)号：KR100840547B1

公开(公告)日：2008-06-23

申请号：KR1020070044353

申请日：2007-05-08

Applicant: 강릉원주대학교산학협력단

Inventor： 박신호 ,  김옥선 ,  조순영 ,  김광우 ,  김정식 ,  김혜경 ,  안효영 ,  허길원

IPC: A23L1/20 ,  A23L1/29

CPC classification number: A23L11/07 ,  A23L33/10 ,  A23P10/22 ,  A23V2002/00 ,  A23V2250/511

Abstract: A preparation method of a bean curd product using beta-chitosan is provided to obtain high-quality functional bean curd with enhanced solidity, elasticity and texture. A preparation method of a bean curd product using beta-chitosan comprises the steps of: (i) washing soybeans and soaking them in water at 10~30°C for 5~15hr; (ii) drying the soaked soybeans, adding distilled water to the dried soybeans, and grinding them; (iii) filtering the ground soybeans with cotton cloth, mixing distilled water heated to 95~100°C with the filtered ground soybeans, and filtering the mixture to make soybean milk; (iv) raising the temperature of the soybean milk to 95~100°C, putting 5~20% of brine containing beta-chitosan into the soybean milk (based on the total volume of the soybean milk), and stirring them to make a coagulated soybean milk; (v) putting the coagulated soybean milk in a mold, and pressing it for 15~25min to make bean curd; and (vi) soaking the bean curd in running water for 15~25min, and laying it on a drying rack for 10~20min to remove the water on its surface. In the step (ii), the volume ratio of the dried soybeans and the distilled water is 1:8~10. In the step (iii), the volume ratio of the filtered ground soybeans and the heated distilled water is 1:3~5. In the step (iv), the brine contains 0.05~2% of beta-chitosan(1000~5000kDa), based on the total volume of the brine.

Abstract translation: 提供使用β-壳聚糖的豆腐制品的制备方法，以获得具有增强的坚固性，弹性和质地的高品质功能性豆腐。 使用β-壳聚糖的豆腐制品的制备方法包括以下步骤：（i）洗涤大豆并在10〜30℃的水中浸泡5〜15小时; （ii）干燥浸泡的大豆，向干燥的大豆中加入蒸馏水并研磨; （iii）用棉布过滤磨碎的大豆，将加热至95〜100℃的蒸馏水与过滤的大豆混合物过滤，过滤混合物制成豆浆; （iv）将豆浆的温度升高至95〜100℃，将5〜20％的含有β-壳聚糖的盐水放入豆浆中（基于豆浆的总体积），并搅拌使其成为 凝结豆浆; （v）将凝固的豆浆放入模具中，压制15〜25min，制成豆腐; 和（vi）将豆腐浸泡在自来水中15〜25分钟，放置在干燥架上10〜20分钟以除去水面。 在步骤（ii）中，干燥的大豆和蒸馏水的体积比为1:8〜10。 在步骤（iii）中，过滤的大豆和加热的蒸馏水的体积比为1:3〜5。 在步骤（iv）中，基于盐水的总体积，盐水含有0.05〜2％的β-壳聚糖（1000〜5000kDa）。