THE RESOLUTION OF RACEMENTS OF 2-ARYL-2-ALKYL-.OMEGA.-ALKYLAMINOALKANE-NITRILES

    公开(公告)号:CA2210337A1

    公开(公告)日:1996-08-08

    申请号:CA2210337

    申请日:1996-01-20

    Applicant: BASF AG

    Abstract: A process is disclosed for separating racemates of phenyl acetonitriles having the formula (I), in which R1, R2, R3 and n have the meaning given in the description. The process consists in dissolving the racemates (I) in a polar solvent, adding thereto 0.5 to 1.0 mole of optically active camphosulphonic acid per mole of compound (I), heating the mixture up to 40 to 100 ~C, letting it cool down and extracting the optically active phenyl acetonitrile (I) from the thus obtained salt.

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    发明专利
    未知

    公开(公告)号:PT808302E

    公开(公告)日:2000-09-29

    申请号:PT96901746

    申请日:1996-01-20

    Applicant: BASF AG

    Abstract: PCT No. PCT/EP96/00236 Sec. 371 Date Jul. 7, 1997 Sec. 102(e) Date Jul. 7, 1997 PCT Filed Jan. 20, 1996 PCT Pub. No. WO96/23764 PCT Pub. Date Aug. 8, 1996A process for resolving the racemates of phenylacetonitriles of the formula I I where R1, R2, R3 and m have the meanings stated in the description is described. The process comprises dissolving the racemates I in a polar solvent, adding from 0.5 to 1.0 mol of optically active camphorsulfonic acid per mol of compound I, heating to 40 DEG -100 DEG C., allowing to cool and liberating the optically active phenylacetonitrile I from the salt obtained in this way.

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