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公开(公告)号:HUE030521T2
公开(公告)日:2017-05-29
申请号:HUE07727257
申请日:2007-03-23
Applicant: BASF SE
Inventor: ZELDER OSKAR , JEONG WEOL KYU , KLOPPROGGE CORINNA , HEROLD ANDREA , SCHROEDER HARTWIG
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公开(公告)号:CA2947663A1
公开(公告)日:2015-11-12
申请号:CA2947663
申请日:2015-05-07
Applicant: BASF SE
Inventor: KRAWCZYK JOANNA MARTYNA , HAEFNER STEFAN , SCHROEDER HARTWIG , ZELDER OSKAR
Abstract: The present invention relates to a modified microorganism having, compared to its wildtype, -a reduced activity of an enzyme encoded by the ptsA-gene, -a reduced activity of an enzyme encoded by the ptsH-gene or -a reduced activity of an enzyme encoded by the ptsA-gene and a reduced activity of an enzyme encoded by the ptsH-gene, wherein the wildtype from which the modified microorganism has been derived belongs to the family of Pasteurellaceae. The present invention also relates to a method for producing succinic acid and to the use of modified microorganisms.
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公开(公告)号:MX2015002294A
公开(公告)日:2015-10-09
申请号:MX2015002294
申请日:2013-08-13
Applicant: BASF SE
Inventor: SCHRÖDER HARTWIG , HOFF BIRGIT , KÖRBER KARSTEN , HAEFNER STEFAN , ZELDER OSKAR , FOLLY CHRISTOPHE , NAESBY MICHAEL , NIELSEN CURT AIMÉ FRIIS , HATSCH ANAELLE , SCHWAB MARKUS , MOLT ANDREA , DITRICH KLAUS , BREUER MICHAEL , HARTMANN HOLGER
IPC: C12N1/21 , A61K31/48 , C07K14/195 , C07K14/37 , C07K16/00 , C12N1/15 , C12N1/16 , C12N15/31 , C12N15/52 , C12N15/80 , C12N15/81 , C12P1/00 , C12P17/10
Abstract: La invención, en principio, pertenece al campo de la fabricación recombinante de alcaloides de tipo clavina tales como cicloclavina, festuclavina, agroclavina, chanoclavina y aldehído de chanoclavina. Proporciona microorganismos y procesos para la fabricación de alcaloides de tipo clavina así como también polipéptidos, polinucleótidos y vectores que comprenden dichos polinucleótidos que se pueden aplicar en un método para la fabricación de alcaloides de tipo clavina.
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公开(公告)号:BRPI0908458A2
公开(公告)日:2015-08-18
申请号:BRPI0908458
申请日:2009-02-04
Applicant: BASF SE
Inventor: ZELDER OSKAR , JEONG WEOL KYU , KLOPPROGGE CORINNA , HEROLD ANDREA , SCHRÖDER HARTWIG
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公开(公告)号:CA2932046A1
公开(公告)日:2015-06-18
申请号:CA2932046
申请日:2014-12-04
Applicant: BASF SE
Inventor: HOFF BIRGIT , MOLT ANDREA , HAEFNER STEFAN , ZELDER OSKAR
IPC: C12P25/00
Abstract: The present invention relates to a method of producing riboflavin in a genetically modified organism of the genus Eremothecium, wherein said genetic modification is linked to the fatty acid uptake and/or beta-oxidation pathway of said organism, comprising growing said organisms in a culture medium and isolating riboflavin from the culture medium. The invention further relates to a method of providing a riboflavin accumulating organism belonging to the genus Eremothecium by genetically modifying said organism, to organisms obtained by such a method, as well as the use of such genetically modified organisms for increasing the accumulation of riboflavin.
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公开(公告)号:CL2015000015A1
公开(公告)日:2015-03-06
申请号:CL2015000015
申请日:2015-01-05
Applicant: BASF SE , WINTERSHALL HOLDING GMBH
Inventor: BROCKMANN BEATA , HEROLD ANDREA , ZELDER OSKAR , HAEFNER STEFAN , FLECK CHRISTIAN , SCHRÖDER HARTWIG , GRANSTRÖM MARI , SCHMIDT JULIA KRISTIANE
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公开(公告)号:PL1957656T3
公开(公告)日:2014-10-31
申请号:PL06830135
申请日:2006-11-27
Applicant: BASF SE
Inventor: POMPEJUS MARKUS , FREYER STEPHAN , LOHSCHEIDT MARKUS , ZELDER OSKAR , BOY MATTHIAS
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公开(公告)号:CA2890416A1
公开(公告)日:2014-05-30
申请号:CA2890416
申请日:2013-11-13
Applicant: BASF SE
Inventor: ZELDER OSKAR , HOFF BIRGIT , SCHRODER HARTWIG , MOLT ANDREA , HARTMANN HOLGER , DITRICH KLAUS , BREUER MICHAEL , REINGRUBER RUDIGER , WEBER JAKOB
IPC: C12N15/11 , A01N37/00 , C07D307/77 , C12N15/63 , C12N15/67
Abstract: The invention pertains to the field of production of natural products and, in particular, in the field of production of cornexistin and hydroxycornexistin. It provides polynucleotides encoding polypeptides involved in the biosynthesis of cornexistin and hydroxycornexistin as well as vectors and recombinant microorganisms comprising such polynucleotides. Also provided are methods for the production of natural products, in particular methods for the production of cornexistin and hydroxycornexistin, using such polynucleotides and polpeptides encoded therein, as well as vectors and recombinant microorganisms comprising such polynucleotides and polypeptides.
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公开(公告)号:PT1921150E
公开(公告)日:2013-10-08
申请号:PT07123783
申请日:2004-12-15
Applicant: BASF SE
Inventor: ZELDER OSKAR , SCHROEDER HARTWIG , KROGER BURKHARD , KLOPPROGGE CORINNA , HAEFNER STEFAN
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公开(公告)号:ES2376035T3
公开(公告)日:2012-03-08
申请号:ES07123761
申请日:2005-07-16
Applicant: BASF SE
Inventor: ZELDER OSKAR , KLOPPROGGE CORINNA , KROEGER BURKHARD , SCHROEDER HARTWIG , HAEFNER STEFAN
Abstract: Método para modificar o causar la rata de transcripción de genes en microorganismos en comparación con el tipo silvestre mediante regulación de la transcripción de genes en el microorganismo por ácidos nucleicos con actividad de promotor, que contiene A) la secuencia de ácido nucleico SEQ.ID.NO. 1 o B) una secuencia derivada de esta secuencia por sustitución, inserción o deleción de nucleótidos, que tiene una identidad de al menos 90 % a nivel de ácido nucleico con la secuencia SEQ.ID.NO. 1 o C) una secuencia de ácido nucleico que hibrida con la secuencia de ácido nucleico SEQ.ID.NO. 1 en condiciones estrictas, en cuyo caso los genes respecto de los ácidos nucleicos con actividad de promotor son heterólogos.
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