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公开(公告)号：AU2014206958A1
公开(公告)日：2015-08-06
申请号：AU2014206958
申请日：2014-01-15
Applicant: BASF SE
Inventor： BONNEKESSEL MELANIE , REICHERT WOLFGANG , HOOCK RALF , KAEDING THOMAS , KORADIN CHRISTOPHER , PLETSCH ANDREAS , EHRESMANN MANFRED , SCHRODER HARTWIG
IPC: C07D493/04 , A01N43/90
Abstract: The present invention relates to a method for preparing the pyripyropene compound of the formula (I) which method comprises the following steps: i) subjecting a pyripyropene compound of formula Pyripyropene A to an alkaline hydrolysis to yield a 1,7,11-trideacetylpyripyropene A, ii) reacting 1,7,11-trideacetylpyripyropene A obtained in step i) with cyclopropane carbonyl chloride to yield a raw product containing the pyripyropene compound of formula (I); iii) subjecting the raw product of step ii) to crystallization to yield a crystalline pyripyropene compound of formula (I) and a mother liquor;and iv) recycling the mother liquor or a pyripyropene compound containing fraction thereof to the alkaline hydrolysis of step i).
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公开(公告)号：CA2924088A1
公开(公告)日：2015-04-02
申请号：CA2924088
申请日：2014-09-11
Applicant: BASF SE
Inventor： SCHRODER HARTWIG , HARTMANN HOLGER , WANG QINGZHAO , RATANI SHAKIR , GUO ZHEYUAN , POMPEJUS MARKUS
Abstract: Provided are a recombinant nucleic acid molecule, a recombinant microorganism, and a method for producing alanine. Also provided is the use of the recombinant nucleic acid molecule or the recombinant microorganism for the fermentative production of alanine.
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公开(公告)号：CA2898115A1
公开(公告)日：2014-07-24
申请号：CA2898115
申请日：2014-01-15
Applicant: BASF SE
Inventor： BONNEKESSEL MELANIE , REICHERT WOLFGANG , HOOCK RALF , KAEDING THOMAS , KORADIN CHRISTOPHER , PLETSCH ANDREAS , EHRESMANN MANFRED , SCHRODER HARTWIG
IPC: C07D493/04 , A01N43/90
Abstract: The present invention relates to a method for preparing the pyripyropene compound of the formula (I) which method comprises the following steps: i) subjecting a pyripyropene compound of formula Pyripyropene A to an alkaline hydrolysis to yield a 1,7,11-trideacetylpyripyropene A, ii) reacting 1,7,11-trideacetylpyripyropene A obtained in step i) with cyclopropane carbonyl chloride to yield a raw product containing the pyripyropene compound of formula (I); iii) subjecting the raw product of step ii) to crystallization to yield a crystalline pyripyropene compound of formula (I) and a mother liquor;and iv) recycling the mother liquor or a pyripyropene compound containing fraction thereof to the alkaline hydrolysis of step i).
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公开(公告)号：CA2890416A1
公开(公告)日：2014-05-30
申请号：CA2890416
申请日：2013-11-13
Applicant: BASF SE
Inventor： ZELDER OSKAR , HOFF BIRGIT , SCHRODER HARTWIG , MOLT ANDREA , HARTMANN HOLGER , DITRICH KLAUS , BREUER MICHAEL , REINGRUBER RUDIGER , WEBER JAKOB
IPC: C12N15/11 , A01N37/00 , C07D307/77 , C12N15/63 , C12N15/67
Abstract: The invention pertains to the field of production of natural products and, in particular, in the field of production of cornexistin and hydroxycornexistin. It provides polynucleotides encoding polypeptides involved in the biosynthesis of cornexistin and hydroxycornexistin as well as vectors and recombinant microorganisms comprising such polynucleotides. Also provided are methods for the production of natural products, in particular methods for the production of cornexistin and hydroxycornexistin, using such polynucleotides and polpeptides encoded therein, as well as vectors and recombinant microorganisms comprising such polynucleotides and polypeptides.
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公开(公告)号：CA2898115C
公开(公告)日：2021-03-02
申请号：CA2898115
申请日：2014-01-15
Applicant: BASF SE
Inventor： BONNEKESSEL MELANIE , REICHERT WOLFGANG , HOOCK RALF , KAEDING THOMAS , KORADIN CHRISTOPHER , PLETSCH ANDREAS , EHRESMANN MANFRED , SCHRODER HARTWIG
IPC: C07D493/04 , A01N43/90
Abstract: The present invention relates to a method for preparing the pyripyropene compound of the formula (I) which method comprises the following steps: i) subjecting a pyripyropene compound of formula Pyripyropene A to an alkaline hydrolysis to yield a 1,7,11-trideacetylpyripyropene A, ii) reacting 1,7,1 1-trideacetylpyripyropene A obtained in step i) with cyclopropane carbonyl chloride to yield a raw product containing the pyripyropene compound of formula (I); iii) subjecting the raw product of step ii) to crystallization to yield a crystalline pyripyropene compound of formula (I) and a mother liquor;and iv) recycling the mother liquor or a pyripyropene compound containing fraction thereof to the alkaline hydrolysis of step i).
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Patent Agency Ranking
公开(公告)号：CA2875603A1
公开(公告)日：2014-01-09
申请号：CA2875603
申请日：2013-07-03
Applicant: WINTERSHALL HOLDING GMBH , BASF SE
Inventor： BROCKMANN BEATA , HEROLD ANDREA , ZELDER OSKAR , HAEFNER STEFAN , FLECK CHRISTIAN , SCHRODER HARTWIG , GRANSTROM MARI , SCHMIDT JULIA KRISTIANE
Abstract: The present invention relates to genetically modified microorganisms capable of producing beta-glucans, characterized in that said genetically modified microorganism overexpresses (i) a polynucleotide encoding a polypeptide having 1,3-ß-D-glucan synthase-activity, and/or (ii) a polypeptide having 1,3-ß-glucan synthase-activity, compared to a corresponding non-modified control microorganism of the same strain. The present invention also relates to the use of a polynucleotide encoding a polypeptide having 1,3-ß-D-glucan synthase-activity or the use of such a polypeptide for producing ß-glucans. Furthermore, the present invention relates to methods for producing ß-glucans comprising the introduction of a promoter upstream of a polynucleotide encoding a polypeptide having 1,3-ß-D-glucan synthase-activity thereby increasing the expression of said polynucleotide, or a polynucleotide encoding a polypeptide having 1,3-ß-D-glucan synthase-activity into a microorganism being able to synthesize ß-glucans.
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公开(公告)号：AU2009211870A1
公开(公告)日：2009-08-13
申请号：AU2009211870
申请日：2009-02-04
Applicant: BASF SE
Inventor： JEONG WEOL KYU , HEROLD ANDREA , ZELDER OSKAR , KLOPPROGGE CORINNA , SCHRODER HARTWIG
Abstract: The present invention relates to a novel method for the fermentative production of dipicolinate by cultivating a recombinant microorganism expressing an enzyme having dipicolinate synthetase activity. The present invention also relates to corresponding recombinant hosts, recombinant vectors, expression cassettes and nucleic acids suitable for preparing such hosts as well as a method of preparing polyester or polyamide copolymers making use of dipicolinate as obtained by fermentative production.
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公开(公告)号：ES2322607T3
公开(公告)日：2009-06-23
申请号：ES05806536
申请日：2005-11-15
Applicant: BASF SE
Inventor： STURMER RAINER , HAUER BERNHARD , DREW DEJANA , BREUER MICHAEL , SCHRODER HARTWIG
Abstract: Método para la preparación de (S)-butan-2-ol mediante la reducción de butan-2-ona en presencia de una alcoholdeshidrogenasa (i) con la secuencia polipeptídica SEQ ID NO:2, o (ii) con una secuencia polipeptídica que presenta al menos un 80% de identidad secuencial con SEQ ID NO:
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公开(公告)号：AU2013349330B2
公开(公告)日：2019-08-01
申请号：AU2013349330
申请日：2013-11-13
Applicant: BASF SE
Inventor： ZELDER OSKAR , HOFF BIRGIT , SCHRODER HARTWIG , MOLT ANDREA , HARTMANN HOLGER , DITRICH KLAUS , BREUER MICHAEL , REINGRUBER RUDIGER , WEBER JAKOB
IPC: C12N15/11 , A01N37/00 , C07D307/77 , C12N15/63 , C12N15/67
Abstract: The invention pertains to the field of production of natural products and, in particular, in the field of production of cornexistin and hydroxycornexistin. It provides polynucleotides encoding polypeptides involved in the biosynthesis of cornexistin and hydroxycornexistin as well as vectors and recombinant microorganisms comprising such polynucleotides. Also provided are methods for the production of natural products, in particular methods for the production of cornexistin and hydroxycornexistin, using such polynucleotides and polpeptides encoded therein, as well as vectors and recombinant microorganisms comprising such polynucleotides and polypeptides.
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公开(公告)号：AU2014242607B2
公开(公告)日：2017-10-19
申请号：AU2014242607
申请日：2014-03-03
Applicant: BASF SE
Inventor： ERNST BURKHARD , EHRESMANN MANFRED , KORADIN CHRISTOPHER , PLETSCH ANDREAS , BONNEKESSEL MELANIE , KAEDING THOMAS , SCHEIN-ALBRECHT KARIN , DEMMING STEFANIE , WEBER FRANZ , SIEGEL WOLFGANG , SCHRODER HARTWIG , FREYER STEPHAN , ODMAN PETER
IPC: C12P17/18
Abstract: The invention pertains to processes to produce dry biomass of pyripyropene producer organisms, processes to obtain pyripyropenes from such dry biomass, as well as to processes to produce compounds of Formula (III) and/or Formula (IV) and/or Formula (V) from the pyripyropenes obtained from the dry biomass. The invention does further pertain to the dry biomass itself, as well as processes using said dry biomass to obtain pyripyropenes for the production of compounds of Formula (III) and/or Formula (IV) and/or Formula (V), including processes using said dry biomass to obtain pyripyropenes or compounds of Formula III and/or Formula (IV) and/or Formula (V) in order to produce pest control compositions, in particular insecticides, comprising such compounds.
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