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公开(公告)号:AT342740T
公开(公告)日:2006-11-15
申请号:AT99925587
申请日:1999-05-10
Applicant: BAXTER INT
Inventor: CHAPMAN JOHN R , STARK PETER R H , SWALLOW MICHAEL V , LARSON DALE N
IPC: A61L2/08 , A01N1/02 , A61K35/14 , A61K35/16 , A61L2/00 , A61M1/36 , C12N7/04 , H01J37/20 , A61L2/10 , A61L2/16 , A61L2/26
Abstract: Apparatus and methods for treating a biological fluid with light and for inactivating contaminants in biological fluid. The biological fluid is contacted with a light source providing a high intensity light to the biological fluid. The biological fluid may include a quantity of a photochemical agent that when activated by light is operable to cause inactivation of at least some of the contaminants.
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公开(公告)号:CA2242966C
公开(公告)日:2006-02-14
申请号:CA2242966
申请日:1997-10-23
Applicant: BAXTER INT
Inventor: CHAPMAN JOHN R , STARK PETER R , CUFFARO DANIEL F , LARSON DALE N , REED MICHAEL A
Abstract: Apparatus and methods for treating a biological fluid with light and for inactivating contaminants in biological fluid. The biological fluid is contacted with a light source (24) providing a high intensity light to the biological fluid. The biological flu id may include a quantity of a photochemical agent that, when activated by light, is operab le to cause inactivation of at least some of the contaminants. The apparatus includes a light box (10), including a retractable shutter assembly (26) that encloses the light source (24). The shutter assembly (26) includes a cylindrical tube (41) that, when raised, shields th e light source (24). In addition, cylindrical tube (28), attached to platform (36) of base assemb ly (22), encloses the light source (24) and the shutter assembly (26).
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公开(公告)号:DE69525938T2
公开(公告)日:2002-11-21
申请号:DE69525938
申请日:1995-12-08
Applicant: BAXTER INT
Inventor: CHAPMAN JOHN R , LO YING-CHENG , KUBEY WINNIE , HOLMES CLIFFORD J , BELL DAVID
IPC: A61L2/16 , A01N25/10 , A01N25/34 , A01N59/00 , A01N59/12 , A61L2/00 , A61L29/00 , A61L29/16 , A61L31/00 , A61L31/16 , B01D67/00 , C08J7/06 , C08K3/00 , C08K3/10 , C08K3/16 , C08L23/00 , C08L25/04 , C08L67/00 , C08L67/02 , C08L69/00 , C08L101/00
Abstract: An antimicrobial material incorporated with a molecular halogen is provided. The antimicrobial material includes a plastic material and a molecular halogen entrapped within the plastic material. A directional release material is also provided in the present application. The directional release material allows for the control of the rate and site of halogen release. Still further, method of impregnating a plastic material is also provided.
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公开(公告)号:AU750131B2
公开(公告)日:2002-07-11
申请号:AU4183899
申请日:1999-05-10
Applicant: BAXTER INT
Inventor: CHAPMAN JOHN R , STARK PETER R H , SWALLOW MICHAEL V , LARSON DALE N
IPC: A61L2/08 , A01N1/02 , A61K35/14 , A61K35/16 , A61L2/00 , A61M1/36 , C12N7/04 , H01J37/20 , A61L2/10 , A61L2/16
Abstract: Apparatus and methods for treating a biological fluid with light and for inactivating contaminants in biological fluid. The biological fluid is contacted with a light source providing a high intensity light to the biological fluid. The biological fluid may include a quantity of a photochemical agent that when activated by light is operable to cause inactivation of at least some of the contaminants.
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公开(公告)号:AT203058T
公开(公告)日:2001-07-15
申请号:AT93905006
申请日:1993-02-09
Applicant: BAXTER INT
Inventor: CHAPMAN JOHN R
IPC: B01D17/02 , B01D21/24 , B01D21/26 , C12N7/00 , C12Q1/68 , C12Q1/70 , G01N33/49 , G01N33/50 , G01N33/53 , G01N33/569
Abstract: The present invention provides a method for testing a blood unit for viral contamination without rendering the blood unit unusable for therapeutic applications. The method comprises the steps of: removing and collecting from a blood unit a majority of the leukocytes present therein with a leukocyte filter; and using the leukocytes collected in and on the filter to test the blood unit for viral contamination. The present invention also provides a method for validating viral inactivation processes.
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公开(公告)号:NO983329D0
公开(公告)日:1998-07-17
申请号:NO983329
申请日:1998-07-17
Applicant: BAXTER INT
Inventor: CHAPMAN JOHN R , STARK PETER R H , REED MICHAEL A , LARSON DALE N , CUFFARO DANIEL F
Abstract: Apparatus and methods for treating a biological fluid with light and for inactivating contaminants in biological fluid. The biological fluid is contacted with a light source providing a high intensity light to the biological fluid. The biological fluid may include a quantity of a photochemical agent that when activated by light is operable to cause inactivation of at least some of the contaminants.
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公开(公告)号:CA2140455A1
公开(公告)日:1994-12-08
申请号:CA2140455
申请日:1993-06-15
Applicant: BAXTER INT
Inventor: LAKE WILLIAM C , GIESLER RICHARD , VAN EPPS DENNIS , CHAPMAN JOHN R , MARTINSON JEFFREY A , ELLIS DALE R , AONO FREDERICK , BISCHOF DANIEL F
IPC: G01N33/48 , A61K35/14 , A61K35/24 , A61M1/36 , B03B5/28 , C12M1/00 , C12N5/00 , C12N5/06 , C12Q1/02 , C12Q1/24 , G01N33/49 , G01N33/50 , G01N33/53 , G01N33/569 , A61K35/18 , A61K35/28 , B01D21/26 , C12N1/00
Abstract: A method combining the techniques of immunoaffinity separation and continuous flow centrifugal is provided for selective separation of a nucleated heterogeneous cell population from a heterogeneous cell mixture. The heterogeneous cell mixture is intimately contacted to promote binding thereto by particles having attached a substance that actively binds to a specific desired type of cell out of the cell mixture. The particles are selected so that the sedimentation velocity of the particle/cell conjugate differs sufficiently from those of other cells in the cell mixture to allow its separation by means of a continuous flow cell separator. The method rapidly processes large volumes of cell mixture with the high accuracy expected of immunoaffinity separation and can be used to separate, for example, various types of leukocytes from whole blood, bone marrow concentrate, or a peripheral blood stem cell concentrate; or precursors of lymphokine activated killer cells, tumor infiltrating cells, or activated killer monocytes from lymphocyte or monocyte cell concentrates or from a tissue cell preparation.
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公开(公告)号:ZA93918B
公开(公告)日:1993-10-22
申请号:ZA93918
申请日:1993-02-10
Applicant: BAXTER INT
Inventor: CHAPMAN JOHN R
IPC: B01D17/02 , B01D21/24 , B01D21/26 , C12N7/00 , C12Q1/68 , C12Q1/70 , G01N33/49 , G01N33/50 , G01N33/53 , G01N33/569 , G01N
Abstract: The present invention provides a method for testing a blood unit for viral contamination without rendering the blood unit unusable for therapeutic applications. The method comprises the steps of: removing and collecting from a blood unit a majority of the leukocytes present therein with a leukocyte filter; and using the leukocytes collected in and on the filter to test the blood unit for viral contamination. The present invention also provides a method for validating viral inactivation processes.
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公开(公告)号:NO321317B1
公开(公告)日:2006-04-24
申请号:NO20005800
申请日:2000-11-16
Applicant: BAXTER INT
Inventor: CHAPMAN JOHN R , STARK PETER R H , LARSON DALE N , SWALLOW MICHAEL V
IPC: A61L2/08 , A01N1/02 , A61L2/10 , A61K35/14 , A61K35/16 , A61L2/00 , A61L2/16 , A61M1/36 , C12N7/04 , H01J37/20
Abstract: Apparatus and methods for treating a biological fluid with light and for inactivating contaminants in biological fluid. The biological fluid is contacted with a light source providing a high intensity light to the biological fluid. The biological fluid may include a quantity of a photochemical agent that when activated by light is operable to cause inactivation of at least some of the contaminants.
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公开(公告)号:NO983329L
公开(公告)日:1998-09-17
申请号:NO983329
申请日:1998-07-17
Applicant: BAXTER INT
Inventor: CHAPMAN JOHN R , STARK PETER R H , REED MICHAEL A , LARSON DALE N , CUFFARO DANIEL F
Abstract: Apparatus and methods for treating a biological fluid with light and for inactivating contaminants in biological fluid. The biological fluid is contacted with a light source providing a high intensity light to the biological fluid. The biological fluid may include a quantity of a photochemical agent that when activated by light is operable to cause inactivation of at least some of the contaminants.
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