中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

57 records (took 0.025 seconds)

    Process for the preparation of quinazoline derivatives.
    33.
    发明专利
    Process for the preparation of quinazoline derivatives. 未知

    公开(公告)号：ZA967365B

    公开(公告)日：1997-02-28

    申请号：ZA967365

    申请日：1996-08-30

    Applicant: HOECHST AG

    Inventor： PFIRMANN RALF ,  PAPENFUHS THEODOR ,  KRAUSE STEFAN ,  NEUMANN-GRIMM DORIS

    IPC: C07D239/96 ,  C07D

    Abstract: PCT No. PCT/EP96/03632 Sec. 371 Date May 22, 1998 Sec. 102(e) Date May 22, 1998 PCT Filed Aug. 19, 1996 PCT Pub. No. WO97/08154 PCT Pub. Date Mar. 6, 1997A process for producing 1,2,3,4-tetrahydro-2,4-dioxo-quinazoline-1-yl acetic acid derivatives of the formula (I) in which R1, R2, R3 and R4 are mutually independently hydrogen, halogen, OH, NO2, (C1-C6) alkoxy, (C1-C6) alkyl, halogen-substituted (C1-C6) alkyl, R5 is hydrogen, (C1-C6) alkyl, phenyl where the alkyl or phenyl radical may also be substituted by halogen atoms; in which an anthranilic acid derivative of formula (II), in which R1 to R5 have the above meaning and R6 is hydrogen, (C1-C6) alkyl or phenyl, where the alkyl or phenyl radical may also be substituted by halogen atoms, is reacted with a metal cyanate and hydrogen chloride in the presence of an inert solvent.

    PROCESS FOR THE PREPARATION OF SALTS OF SUBSTITUTED OR UNSUBSTITUTED PHTHALIC ACIDS
    36.
    发明专利
    PROCESS FOR THE PREPARATION OF SALTS OF SUBSTITUTED OR UNSUBSTITUTED PHTHALIC ACIDS 未知

    公开(公告)号：CA2175527A1

    公开(公告)日：1996-11-03

    申请号：CA2175527

    申请日：1996-05-01

    Applicant: HOECHST AG

    Inventor： PFIRMANN RALF ,  PAPENFUHS THEODOR

    IPC: C07C51/06 ,  C07C51/00 ,  C07C51/41 ,  C07C51/54 ,  C07C63/68 ,  C07C63/72 ,  C07C65/03 ,  C07C227/18 ,  C07C65/21 ,  C07C229/54

    Abstract: The present invention relates to a process for the preparation of salts of substituted or unsubstituted phthalic acids, by reacting a compound of the formula (1) in which R1, R2, R3 and R4 are identical or different and are H, F, Cl, Br, CF3, OH, an alkoxy or alkyl radical in each case having 1 to 4 carbon atoms, or a radical -NR7R8, in which R7 and R8 are identical or different and are H, an alkyl radical having 1 to 4 carbon atoms, or a phenyl radical, R5 and R6 are identical or different and are H, a -CO- alkyl group having 1 to 6 carbon atoms in the alkyl radical, or a benzoyl group, or R5 and R6 together form a radical of the formula (2) in which R9, R10, R11 and R12 are identical or different and are H, F, Cl, Br, CF3, OH, an alkoxy or alkyl radical in each case having 1 to 4 carbon atoms, or a radical -NR7R8, in which R7 and R8 are identical or different and are H, an alkyl radical having 1 to 4 carbon atoms, or a phenyl radical, with water, a water-soluble base and an oxidizing agent at a temperature of -10 to 150.degree.C in the presence or absence of a water-insoluble solvent inert under the reaction conditions.

Patent Agency Ranking