公开(公告)号：FI912968A0

公开(公告)日：1991-06-18

申请号：FI912968

申请日：1991-06-18

Applicant: HOECHST AG

Inventor： KLESEL NORBERT ,  LIMBERT MICHAEL ,  SCHRINNER ELMAR

IPC: A61K31/52 ,  A61K31/522 ,  A61K31/545 ,  A61K31/546 ,  A61P7/00 ,  A61P9/00 ,  A61P31/00 ,  A61P31/04 ,  A61K

Abstract: Pharmaceutical combination products containing at least one cephalosporin derivative and at least one xanthine derivative are suitable for the prophylaxis and treatment of bacterial infectious diseases and for the prophylaxis and treatment of septic shock.

公开(公告)号：PT95050A

公开(公告)日：1991-04-18

申请号：PT9505090

申请日：1990-08-21

Applicant: HOECHST AG

Inventor： HAENEL HEINZ ,  SCHRINNER ELMAR ,  HANS-LUDWIG

IPC: A61K31/52 ,  A61P43/00

公开(公告)号：AU3793389A

公开(公告)日：1990-01-11

申请号：AU3793389

申请日：1989-07-07

Applicant: HOECHST AG

Inventor： KLOSA JOSEF ,  SCHRINNER ELMAR ,  HELSBERG MATTHIAS ,  WINKLER IRVIN ,  MEICHSNER CHRISTOPH ,  KROGER HANS

IPC: A61K31/52 ,  A61P31/12 ,  C07D473/38

公开(公告)号：DK338389D0

公开(公告)日：1989-07-07

申请号：DK338389

申请日：1989-07-07

Applicant: HOECHST AG

Inventor： KLOSA JOSEF ,  KROEGER HANS ,  MEICHSNER CHRISTOPH ,  WINKLER IRVIN ,  HELSBERG MATTHIAS ,  SCHRINNER ELMAR

IPC: A61K31/52 ,  A61P31/12 ,  C07D473/38

公开(公告)号：AU2017988A

公开(公告)日：1989-02-02

申请号：AU2017988

申请日：1988-07-29

Applicant: HOECHST AG

Inventor： SCHRINNER ELMAR ,  WINKLER IRVIN ,  MEICHSNER CHRISTOPH ,  HELSBERG MATTHIAS

IPC: C07D473/06 ,  A61K20060101 ,  A61K31/52 ,  A61K31/70 ,  A61K31/715 ,  A61P31/12 ,  C07D20060101 ,  C07D473/04 ,  C08B20060101 ,  C08B37/00

Abstract: The preparation contains or consists of… a) at least one sulphated polysaccharide and… b) at least one xanthine derivative. The preparation is suitable for the control and prophylaxis of viral diseases, especially those caused by retroviruses.

公开(公告)号：NO160211B

公开(公告)日：1988-12-12

申请号：NO781130

申请日：1978-03-31

Applicant: HOECHST AG

Inventor： DUERCKHEIMER WALTER ,  BORMANN DIETER ,  EHLERS EBERHARD ,  SCHRINNER ELMAR ,  HEYMES RENE

IPC: A61K31/397 ,  A61K31/435 ,  A61K31/505 ,  A61K31/535 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  B25J15/08 ,  C07D205/08 ,  C07D277/20 ,  C07D277/40 ,  C07D277/42 ,  C07D277/50 ,  C07D463/00 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04 ,  C07D501/20 ,  C07D501/24 ,  C07D501/36 ,  C07D505/00 ,  C07D519/06 ,  C07F9/6561

Abstract: Cephem derivatives of the general formula in which the R2O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.

公开(公告)号：FI872459A

公开(公告)日：1987-12-05

申请号：FI872459

申请日：1987-06-02

Applicant: HOECHST AG

Inventor： LIMBERT MICHAEL ,  SCHRINNER ELMAR ,  SEIBERT GERHARD

IPC: A61K31/545 ,  A61P31/04 ,  A61K

Abstract: Pharmaceutical preparation having a synergistic, antibacterial activity and containing a) a cephalosporin derivative or physiologically acceptable salts or esters thereof, and b) a penem antibiotic of the basic structure (B) or physiologically acceptable salts or esters thereof, process for manufacturing such a preparation, and its use in the treatment of bacterial infections.

公开(公告)号：NO872331D0

公开(公告)日：1987-06-03

申请号：NO872331

申请日：1987-06-03

Applicant: HOECHST AG

Inventor： LIMBERT MICHAEL ,  SCHRINNER ELMAR ,  SEIBERT GERHARD

IPC: A61K31/545 ,  A61P31/04 ,  A61K

Abstract: Pharmaceutical preparation having a synergistic, antibacterial activity and containing a) a cephalosporin derivative or physiologically acceptable salts or esters thereof, and b) a penem antibiotic of the basic structure (B) or physiologically acceptable salts or esters thereof, process for manufacturing such a preparation, and its use in the treatment of bacterial infections.

公开(公告)号：CA1146947A

公开(公告)日：1983-05-24

申请号：CA337692

申请日：1979-10-16

Applicant: HOECHST AG

Inventor： BORMANN DIETER ,  KNABE BERND ,  SCHRINNER ELMAR ,  WORM MANFRED

IPC: C07D277/42

Abstract: CEPHEM DERIVATIVES AND PROCESSES FOR THEIR PREPARATION of the disclosure This application is directed to a process for the preparation of a 2-aminothiazol-4-yl-glyoxylic acid of the formula III III wherein R represents a protective group in which an acetylglyoxylic acid ester wherein Z represents the radical of an alcohol, is halogenated, the resulting compound is reacted with thiourea to give a 2-amino-thiazol-4-yl-glyoxylic acid ester an amino protective group is introduced into the compound and the product is saponified to a carboxylic acid of the general formula III. The application is also directed to these compounds which are valuable intermediates in the preparation of antiobiotics.

公开(公告)号：PH15925A

公开(公告)日：1983-04-26

申请号：PH21988

申请日：1978-12-22

Applicant: HOECHST AG

Inventor： BLUMBACH JUERGEN ,  DUERCKHEIMER WALTER ,  SCHRINNER ELMAR

IPC: C07D501/06 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D277/20 ,  C07D277/46 ,  C07D501/34 ,  C07D501/00

Abstract: Cephalosporin derivatives of the formula I processes for their manufacture and their use for combating bacterial infections.