-
公开(公告)号：JPH1171323A
公开(公告)日：1999-03-16
申请号：JP13548798
申请日：1998-05-18
Applicant: HOECHST AG
Inventor： ARETZ WERNER , BOETTGER DIRK , SEIBERT GERHARD , TUMULKA ALOIS , WELZEL PETER , HOBERT KURT
IPC: A61K31/19 , A61P31/04 , C07C59/125 , C07C59/60 , C07F9/09 , C07F9/655 , C07H13/12 , C07H15/203 , C12N1/20 , C12N9/16 , C12N9/99 , C12P7/42 , C12P9/00 , C12P19/26 , C12P19/44 , C12R1/07
Abstract: PROBLEM TO BE SOLVED: To obtain a new compound useful as an antibacterial agent or its intermediate. SOLUTION: The objective compound is a cleavage product of a phosphoglycolipid antibiotic substance of the formula I (R is H; R is a 5-55C alkyl). A cultured product of Bacillus DSM 4675 or its processed product, especially a separated enzyme is usable for the decomposition of a phosphoglycolipid antibiotic substance, especially antibiotic substances of moenomycin group. Moenomycin A is incubated with moenomycinase preferably at pH 8.2-8.3 and 49-51 deg.C to obtain the compounds of the formula II and III and the compound of the formula III is incubated with an MBase preferably at pH 6-8 and 35-37 deg.C for 24 hr to obtain the compound of the formula IV. The reaction product can be used as an antibiotic substance (e.g. the compound of the formula III) or a basic unit (e.g. the compound of the formula II and IV) in the synthesis of a transglycosylase inhibitor.
-
公开(公告)号：JPS63166886A
公开(公告)日：1988-07-11
申请号：JP32420187
申请日：1987-12-23
Applicant: HOECHST AG
Inventor： HAMMANN PETER , GRABLEY SUSANNE , VOELSKOW HARTMUT , SACHSE BURKHARD , RAETHER WOLFGANG , GIANI CARLO , SEIBERT GERHARD
IPC: C12P17/08 , A01N63/02 , A61K20060101 , A61K31/365 , A61P31/00 , A61P31/10 , C07D313/00 , C07D493/04 , C07D493/08 , C12N20060101 , C12P20060101 , C12P1/02 , C12P17/18 , C12R1/465
-
公开(公告)号：PT864584E
公开(公告)日：2001-05-31
申请号：PT98110484
申请日：1994-06-01
Applicant: HOECHST AG
Inventor： SEIBERT GERHARD , WINK JOACHIM , MEIWES JOHANNES , MARKUS ASTRID , LASZLO VERTESY DR , HAMMANN PETER
IPC: C12P21/02 , A61K38/00 , A61K38/08 , A61K38/12 , A61P31/04 , C07K20060101 , C07K1/20 , C07K7/06 , C07K7/60 , C07K14/195 , C07K14/41 , C12N1/20 , C12P1/06 , C12P21/04 , C12R1/045
Abstract: Lipo-peptides of formula (I), where R1 is a saturated or unsaturated, branched or unbranched, 6-22C fatty acid or hydroxy fatty acid residue other than those of formula (II)-(VII), are new:
-
公开(公告)号：HU9800512A2
公开(公告)日：1998-10-28
申请号：HU9800512
申请日：1998-03-09
Applicant: HOECHST AG
Inventor： KURZ MICHAEL , MARKUS ASTRID , SEIBERT GERHARD , VERTESY LASZLO
IPC: C07H13/12 , A61K31/70 , A61K31/702 , A61K31/7024 , A61K31/7135 , A61P1/00 , A61P1/04 , A61P31/04 , C07F9/94 , C07H21/00 , C07H11/04
Abstract: Bismuth salts (I) of moenomycin-type antibiotics, their derivatives and salts are new.
-
公开(公告)号：HU9800512D0
公开(公告)日：1998-04-28
申请号：HU9800512
申请日：1998-03-09
Applicant: HOECHST AG
Inventor： KURZ MICHAEL , MARKUS ASTRID , SEIBERT GERHARD , VERTESY LASZLO
IPC: C07H13/12 , A61K31/70 , A61K31/702 , A61K31/7024 , A61K31/7135 , A61P1/00 , A61P1/04 , A61P31/04 , C07F9/94 , C07H21/00
Abstract: Bismuth salts (I) of moenomycin-type antibiotics, their derivatives and salts are new.
-
Patent Agency Ranking
公开(公告)号：CA1339421C
公开(公告)日：1997-09-02
申请号：CA591261
申请日：1989-02-16
Applicant: HOECHST AG
Inventor： ADAM FRIEDHELM , MENCKE BURGHARD , BLUMBACH JUERGEN , ISERT DIETER , SEIBERT GERHARD , FISCHER GERD , DUERCKHEIMER WALTER
IPC: A61K20060101 , A61K31/545 , A61K31/546 , A61P31/04 , C07D20060101 , C07D501/00 , C07D501/32 , C07D501/34
Abstract: Cephemcarboxylic acid esters of the general formula pharmaceutical preparations which are active against bacterial infections, which contain such cephem derivatives, a process for the preparation of the cephem derivatives and the pharmaceutical preparations, and also the use of the cephem derivatives for combating bacterial infections.
-
公开(公告)号：FI94648C
公开(公告)日：1995-10-10
申请号：FI893842
申请日：1989-08-15
Applicant: HOECHST AG
-
公开(公告)号：IE64706B1
公开(公告)日：1995-08-23
申请号：IE263889
申请日：1989-08-16
Applicant: HOECHST AG
Inventor： CHATTERJEE SUGATA , GANGULI BIMAL NARESH , CHATTERJEE DEEPAK KUMAR , JANI RAJENDRA KUMAR HARIPRASAD , RUPP RICHARD HELMUT , FEHLHABER HANS-WOLFRAM , KOGLER HERBERT , SEIBERT GERHARD , CHATTERJEE SUKUMAR , TEETZ VOLKER
IPC: C12N1/20 , A61K38/00 , A61P31/04 , C07K7/08 , C07K7/56 , C07K14/195 , C07K14/41 , C12P21/02 , C12P21/04 , C12R1/01 , C12R1/07 , A61K37/02 , C12N1/21
Abstract: Mersacidin, a cyclic peptide of the formula I (I) has antibiotic activity.
-
公开(公告)号：ZA9403983B
公开(公告)日：1995-01-27
申请号：ZA9403983
申请日：1994-06-07
Applicant: HOECHST AG
Inventor： HAMMANN PETER , MEIWES JOHANNES , SEIBERT GERHARD , VERTESY LASZLO , WINK JOACHIM , MARKUS ASTRID
IPC: C12P21/02 , A61K38/00 , A61K38/08 , A61K38/12 , A61P31/04 , C07K20060101 , C07K1/20 , C07K7/06 , C07K7/60 , C07K14/195 , C07K14/41 , C12N1/20 , C12P1/06 , C12P21/04 , C12R1/045 , C07K , A61K
CPC classification number: C07K7/60 , A61K38/00 , Y10S435/827
-
公开(公告)号：AU6462094A
公开(公告)日：1994-12-15
申请号：AU6462094
申请日：1994-06-06
Applicant: HOECHST AG
Inventor： HAMMANN PETER , MEIWES JOHANNES , SEIBERT GERHARD , VERTESY LASZLO , WINK JOACHIM , MARKUS ASTRID
IPC: C12P21/02 , A61K38/00 , A61K38/08 , A61K38/12 , A61P31/04 , C07K20060101 , C07K1/20 , C07K7/06 , C07K7/60 , C07K14/195 , C07K14/41 , C12N1/20 , C12P1/06 , C12P21/04 , C12R1/045 , A61K37/02 , A61K9/50 , A61K9/66 , A61K9/28
Abstract: Lipo-peptides of formula (I), where R1 is a saturated or unsaturated, branched or unbranched, 6-22C fatty acid or hydroxy fatty acid residue other than those of formula (II)-(VII), are new:
-
-
-
-
-
-
-
-
-
Search Results
289
records
(took 0.023 seconds)
