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公开(公告)号：NO20073308A
公开(公告)日：2008-01-02
申请号：NO20073308
申请日：2007-06-28
Applicant: SERVIER LAB
Inventor： SPEDDING MICHAEL , MILLAN MARK , YOUS SAID , BERTHELOT PASCAL , CAIGNARD DANIEL-HENRI , PERES BASILE , SABAOUNI AHMED , DELAGRANGE PHILIPPE
IPC: C07C233/18 , A61P25/20 , A61P25/22 , A61P25/24 , C07C231/06
CPC classification number: C07C233/18
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公开(公告)号：PL195664B1
公开(公告)日：2007-10-31
申请号：PL34183798
申请日：1998-12-11
Applicant: SERVIER LAB
Inventor： LANGLOIS MICHEL , MATHE-ALLAINMAT MONIQUE , JELLIMANN CAROLE , ANDRIEUX JEAN , BENNEJEAN CAROLINE , RENARD PIERRE , DELAGRANGE PHILIPPE
IPC: C07C233/18 , C07D333/74 , A61K31/165 , A61K31/17 , A61K31/343 , A61K31/381 , A61K31/403 , A61P9/06 , A61P25/08 , A61P25/20 , A61P25/22 , A61P35/00 , A61P43/00 , C07C233/05 , C07C233/60 , C07C235/34 , C07C275/24 , C07C275/26 , C07D209/60 , C07D209/90 , C07D307/77 , C07D307/92 , C07D307/93 , C07D333/78
Abstract: The invention concerns compounds of formula (I) in which: A forms a tricyclic system of formula A1, A2, A3 or A4; R1 represents a hydrogen atom, an alkyl, hydroxy, alkoxy or oxo group; (R2)m and (R3)m' are such as defined in the description; n represents an integer such that 0
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33.发明专利
公开(公告)号：AU2001277595B2
公开(公告)日：2006-08-17
申请号：AU2001277595
申请日：2001-07-16
Applicant: SERVIER LAB
Inventor： COSTA HERVE DA , GUILLAUMET GERALD , DESCAMPS-FRANCOIS CAROLE , RENARD PIERRE , YOUS SAID , BENNEJEAN CAROLINE , VIAUD MARIE-CLAUDE , LESIEUR DANIEL , DELAGRANGE PHILIPPE
IPC: C07C233/18 , C07D333/58 , A61K31/235 , A61K31/343 , A61K31/381 , A61K31/4045 , A61K31/437 , A61P3/04 , A61P3/10 , A61P15/00 , A61P25/00 , A61P25/04 , A61P25/16 , A61P25/20 , A61P25/28 , A61P35/00 , C07C231/12 , C07C233/60 , C07D209/08 , C07D209/20 , C07D307/68 , C07D307/79 , C07D307/81 , C07D333/54 , C07D471/04
Abstract: The invention relates to compounds of formula (I): wherein: B represents a hydrogen atom, a COOR group, a CONRR' group, or a (C 1 -C 6 )alkyl group substituted by a COOR, CONRR' or OR group, G 1 represents a -X'-(CH 2 ) n -X-(CH 2 ) m -X''- chain wherein X, X', X'', n and m are as defined in the description, Cy represents a grouping of formula (II) or (III): G 2 represents an alkylene chain as defined in the description, and A represents a NRCOR', NRCSR', CONRR', CSNRR', NRCONR'R'' or NRCSNR'R'' group.
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公开(公告)号：DE69831121T2
公开(公告)日：2006-06-14
申请号：DE69831121
申请日：1998-11-27
Applicant: SERVIER LAB
Inventor： LEFOULON FRANCOIS , DEMUYNCK LUC , LESIEUR DANIEL , DEPREUX PATRICK , BENNEJEAN CAROLINE , RENARD PIERRE , DELAGRANGE PHILIPPE
IPC: C07C233/22 , A61K31/00 , A61K31/10 , A61K31/16 , A61K31/165 , A61K31/17 , A61K31/18 , A61K31/34 , A61K31/341 , A61K31/38 , A61K31/381 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61P25/20 , A61P43/00 , C07C233/05 , C07C233/17 , C07C233/18 , C07C233/31 , C07C233/36 , C07C233/47 , C07C233/58 , C07C233/60 , C07C255/66 , C07C275/24 , C07C309/65 , C07C317/14 , C07C317/22 , C07C317/32 , C07C327/42 , C07C335/06 , C07D213/56 , C07D233/60 , C07D307/12 , C07D307/52 , C07D307/54 , C07D333/16 , C07D333/20
Abstract: Naphthalenic compounds (I), their enantiomers, diastereoisomers, and salts with acids and bases. The naphthalenic compounds are of formula (I) A and B' rings = naphthalene, 1,2-dihydronaphthalene, 2,3- dihydronaphthalene, 1,4- dihydronaphthalene, or tetrahydronaphthalene; T = 1-6C alkylene which may be substituted by one or more 1-6C alkyl, alkoxy, alkoxycarbonyl, OH, or COOH groups; R = H, OH, R', or OR'; R' = 1-6C alkyl, 2-6C alkenyl or alkynyl, 3-7C cycloalkyl, 4-7C cycloalkenyl, aryl, biphenyl, or heteroaryl (these groups being optionally substituted), or 1-6C trihaloalkyl sulfonyl; R may further link with two atoms of ring A and = a 5-7 membered saturated or unsaturated O-containing ring, which may be substituted by 1-6C alkyl, alkoxy, alkoxy-carbonyl, OH, or oxo; G1 = halo (in which case it is linked to ring B'), 1-6C trihalo alkyl sulfonyloxy, COOH, formyl, CN, R1 or -O-CO-R1; R1 = 1-6C alkyl, 2-6C alkenyl or alkynyl, 3-7C cycloalkyl, aryl, biphenyl, or heteroaryl (these groups being optionally substituted); G2 = a group G20, G21, or G22; X = O or S; R2 = H or 1-6C alkyl; R21 = 1-6C alkyl, 2-6C alkenyl or alkynyl, 3-7C cycloalkyl, aryl, biphenyl, or heteroaryl (these groups being optionally substituted) with various provisos listed in the Definitions section.
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公开(公告)号：FR2874611A1
公开(公告)日：2006-03-03
申请号：FR0409202
申请日：2004-08-31
Applicant: SERVIER LAB
Inventor： GUILLAUMET GERALD , BERTEINA RABOIN SABINE , EL KAZZOULI SAID , DELAGRANGE PHILIPPE , CAIGNARD DANIEL HENRI
IPC: C07D471/04 , A61K31/437 , A61P15/00 , A61P25/00 , A61P35/00 , C07D213/74 , C07D233/64
Abstract: Composés de formule (I) :dans laquelle :• A représente un groupement -NHCOR1 ou -CONHR1 dans lesquels R1 est tel que défini dans la description,• R2 représente un groupement alkoxy,• R3 représente un groupement aryle, arylalkyle ou aroyle,Médicaments.
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Patent Agency Ranking
公开(公告)号：AT312073T
公开(公告)日：2005-12-15
申请号：AT99918037
申请日：1999-05-10
Applicant: SERVIER LAB
Inventor： LESIEUR DANIEL , KLUPSCH FREDERIQUE , GUILLAUMET GERALD , VIAUD MARIE-CLAUDE , LANGLOIS MICHEL , BENNEJEAN CAROLINE , RENARD PIERRE , DELAGRANGE PHILIPPE
IPC: C07D295/12 , A61K31/16 , A61K31/165 , A61K31/166 , A61K31/17 , A61K31/18 , A61K31/19 , A61K31/27 , A61K31/341 , A61K31/343 , A61K31/352 , A61K31/357 , A61K31/381 , A61K31/382 , A61K31/4025 , A61K31/403 , A61K31/404 , A61K31/4045 , A61K31/405 , A61K31/4184 , A61K31/423 , A61K31/435 , A61K31/4355 , A61K31/436 , A61K31/4365 , A61K31/437 , A61K31/4402 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/4439 , A61K31/4453 , A61K31/453 , A61K31/454 , A61K31/473 , A61K31/5355 , A61K31/5375 , A61K31/5377 , A61K31/55 , A61P1/00 , A61P3/06 , A61P3/10 , A61P5/02 , A61P9/00 , A61P15/08 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P35/00 , A61P43/00 , C07C233/36 , C07C233/40 , C07C233/43 , C07C233/62 , C07C233/65 , C07C237/48 , C07C271/20 , C07C271/30 , C07C275/24 , C07C275/40 , C07C311/46 , C07C317/32 , C07C323/40 , C07C323/41 , C07C323/44 , C07C323/62 , C07D207/26 , C07D207/27 , C07D209/08 , C07D209/14 , C07D209/16 , C07D209/18 , C07D209/20 , C07D209/60 , C07D209/90 , C07D213/70 , C07D221/08 , C07D221/10 , C07D233/42 , C07D233/84 , C07D235/06 , C07D235/14 , C07D261/20 , C07D295/18 , C07D307/68 , C07D307/77 , C07D307/81 , C07D307/92 , C07D311/58 , C07D311/60 , C07D311/92 , C07D319/18 , C07D319/20 , C07D333/20 , C07D333/38 , C07D333/40 , C07D333/50 , C07D333/56 , C07D333/58 , C07D333/74 , C07D335/06 , C07D335/08 , C07D401/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D407/12 , C07D409/06 , C07D471/04 , C07D471/14 , C07D491/04 , C07D491/048 , C07D491/052 , C07D493/04 , C07D495/04 , C07D495/14 , C07D521/00 , C07C311/37 , C07D307/85
Abstract: The invention concerns compounds of formula (I): R-A-R' wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R 1 , R 2 , R 3 , v and R 4 are as defined in the description; R' represents a -(CH 2 )t-R 5 group wherein t and R 5 are as defined in the description.
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公开(公告)号：DK1317413T3
公开(公告)日：2005-11-21
申请号：DK01955425
申请日：2001-07-16
Applicant: SERVIER LAB
Inventor： VIAUD MARIE-CLAUDE , LESIEUR DANIEL , BENNEJEAN CAROLINE , DELAGRANGE PHILIPPE , RENARD PIERRE , DESCAMPS-FRANCOIS CAROLE , YOUS SAID RESIDENCE MARTHE ALE , GUILLAUMET GERALD , DA COSTA HERVE
IPC: C07D333/58 , A61K31/235 , A61K31/343 , A61K31/381 , A61K31/4045 , A61K31/437 , A61P3/04 , A61P3/10 , A61P15/00 , A61P25/00 , A61P25/04 , A61P25/16 , A61P25/20 , A61P25/28 , A61P35/00 , C07C231/12 , C07C233/18 , C07C233/60 , C07D209/08 , C07D209/20 , C07D307/68 , C07D307/79 , C07D307/81 , C07D333/54 , C07D471/04 , A61K31/165 , A61K31/335 , A61K31/38 , A61K31/40 , C07C209/16
Abstract: The invention relates to compounds of formula (I): wherein: B represents a hydrogen atom, a COOR group, a CONRR' group, or a (C 1 -C 6 )alkyl group substituted by a COOR, CONRR' or OR group, G 1 represents a -X'-(CH 2 ) n -X-(CH 2 ) m -X''- chain wherein X, X', X'', n and m are as defined in the description, Cy represents a grouping of formula (II) or (III): G 2 represents an alkylene chain as defined in the description, and A represents a NRCOR', NRCSR', CONRR', CSNRR', NRCONR'R'' or NRCSNR'R'' group.
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公开(公告)号：DK0919541T3
公开(公告)日：2005-10-17
申请号：DK98402963
申请日：1998-11-27
Applicant: SERVIER LAB
Inventor： RENARD PIERRE , LEFOULON FRANCOIS , DEMUYNCK LUC , LESIEUR DANIEL , DEPREUX PATRICK , BENNEJEAN CAROLINE , DELAGRANGE PHILIPPE
IPC: A61K31/00 , A61K31/10 , A61K31/16 , A61K31/165 , A61K31/17 , A61K31/18 , A61K31/34 , A61K31/341 , A61K31/38 , A61K31/381 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61P25/20 , A61P43/00 , C07C233/05 , C07C233/17 , C07C233/18 , C07C233/22 , C07C233/31 , C07C233/36 , C07C233/47 , C07C233/58 , C07C233/60 , C07C255/66 , C07C275/24 , C07C309/65 , C07C317/14 , C07C317/22 , C07C317/32 , C07C327/42 , C07C335/06 , C07D213/56 , C07D233/60 , C07D307/12 , C07D307/52 , C07D307/54 , C07D333/16 , C07D333/20
Abstract: Naphthalenic compounds (I), their enantiomers, diastereoisomers, and salts with acids and bases. The naphthalenic compounds are of formula (I) A and B' rings = naphthalene, 1,2-dihydronaphthalene, 2,3- dihydronaphthalene, 1,4- dihydronaphthalene, or tetrahydronaphthalene; T = 1-6C alkylene which may be substituted by one or more 1-6C alkyl, alkoxy, alkoxycarbonyl, OH, or COOH groups; R = H, OH, R', or OR'; R' = 1-6C alkyl, 2-6C alkenyl or alkynyl, 3-7C cycloalkyl, 4-7C cycloalkenyl, aryl, biphenyl, or heteroaryl (these groups being optionally substituted), or 1-6C trihaloalkyl sulfonyl; R may further link with two atoms of ring A and = a 5-7 membered saturated or unsaturated O-containing ring, which may be substituted by 1-6C alkyl, alkoxy, alkoxy-carbonyl, OH, or oxo; G1 = halo (in which case it is linked to ring B'), 1-6C trihalo alkyl sulfonyloxy, COOH, formyl, CN, R1 or -O-CO-R1; R1 = 1-6C alkyl, 2-6C alkenyl or alkynyl, 3-7C cycloalkyl, aryl, biphenyl, or heteroaryl (these groups being optionally substituted); G2 = a group G20, G21, or G22; X = O or S; R2 = H or 1-6C alkyl; R21 = 1-6C alkyl, 2-6C alkenyl or alkynyl, 3-7C cycloalkyl, aryl, biphenyl, or heteroaryl (these groups being optionally substituted) with various provisos listed in the Definitions section.
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公开(公告)号：FR2857010B1
公开(公告)日：2005-09-16
申请号：FR0307949
申请日：2003-07-01
Applicant: SERVIER LAB
Inventor： LANGLOIS MICHEL , MATHE ALLAINMAT MONIQUE , CHAHED MONCEF AMINE , BOUTIN JEAN ALBERT , AUDINOT VALERIE , BENNEJEAN CAROLINE , DELAGRANGE PHILIPPE , RENARD PIERRE
IPC: A61P25/00 , A61P35/00 , C07C233/05 , A61K31/165
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公开(公告)号：DE69831121D1
公开(公告)日：2005-09-15
申请号：DE69831121
申请日：1998-11-27
Applicant: SERVIER LAB
Inventor： LEFOULON FRANCOIS , DEMUYNCK LUC , LESIEUR DANIEL , DEPREUX PATRICK , BENNEJEAN CAROLINE , RENARD PIERRE , DELAGRANGE PHILIPPE
IPC: A61K31/00 , A61K31/10 , A61K31/16 , A61K31/165 , A61K31/17 , A61K31/18 , A61K31/34 , A61K31/341 , A61K31/38 , A61K31/381 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61P25/20 , A61P43/00 , C07C233/05 , C07C233/17 , C07C233/18 , C07C233/22 , C07C233/31 , C07C233/36 , C07C233/47 , C07C233/58 , C07C233/60 , C07C255/66 , C07C275/24 , C07C309/65 , C07C317/14 , C07C317/22 , C07C317/32 , C07C327/42 , C07C335/06 , C07D213/56 , C07D233/60 , C07D307/12 , C07D307/52 , C07D307/54 , C07D333/16 , C07D333/20
Abstract: Naphthalenic compounds (I), their enantiomers, diastereoisomers, and salts with acids and bases. The naphthalenic compounds are of formula (I) A and B' rings = naphthalene, 1,2-dihydronaphthalene, 2,3- dihydronaphthalene, 1,4- dihydronaphthalene, or tetrahydronaphthalene; T = 1-6C alkylene which may be substituted by one or more 1-6C alkyl, alkoxy, alkoxycarbonyl, OH, or COOH groups; R = H, OH, R', or OR'; R' = 1-6C alkyl, 2-6C alkenyl or alkynyl, 3-7C cycloalkyl, 4-7C cycloalkenyl, aryl, biphenyl, or heteroaryl (these groups being optionally substituted), or 1-6C trihaloalkyl sulfonyl; R may further link with two atoms of ring A and = a 5-7 membered saturated or unsaturated O-containing ring, which may be substituted by 1-6C alkyl, alkoxy, alkoxy-carbonyl, OH, or oxo; G1 = halo (in which case it is linked to ring B'), 1-6C trihalo alkyl sulfonyloxy, COOH, formyl, CN, R1 or -O-CO-R1; R1 = 1-6C alkyl, 2-6C alkenyl or alkynyl, 3-7C cycloalkyl, aryl, biphenyl, or heteroaryl (these groups being optionally substituted); G2 = a group G20, G21, or G22; X = O or S; R2 = H or 1-6C alkyl; R21 = 1-6C alkyl, 2-6C alkenyl or alkynyl, 3-7C cycloalkyl, aryl, biphenyl, or heteroaryl (these groups being optionally substituted) with various provisos listed in the Definitions section.
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