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公开(公告)号：KR1020140012579A
公开(公告)日：2014-02-03
申请号：KR1020120140398
申请日：2012-12-05
Applicant: 한국전자통신연구원
IPC: G01N35/10 , G01N33/493 , G01N33/566 , G01N1/14
CPC classification number: G01N35/1079 , G01N33/493 , G01N33/566 , G01N35/1009 , G01N2001/1445
Abstract: The present invention relates to a bio cartridge which comprises: a reaction chamber in which a reagent embedded in a housing is stored; a clinical specimen transfer channel which provides a transfer path to the reaction chamber of a clinical specimen supplied to the housing; a mixing device which mixes the clinical specimen and the reagent; and a pneumatic device which provides pneumatic to the clinical specimen. The pneumatic device includes an air injection needle which can be entered into a test collection device and an air transfer channel connected to the air injection needle. The mixing device includes a magnetic agitation member arranged inside the reaction chamber with the reagent and a rotary device which provides torque to the magnetic agitation member. The rotary device includes a motor including a magnetic in one od of a rotary shaft.
Abstract translation: 生物药筒技术领域本发明涉及一种生物药筒，其特征在于，包括：反应室，其中嵌入在壳体内的试剂被贮存; 临床样本转移通道，其提供供给到壳体的临床试样的反应室的输送路径; 将临床标本和试剂混合的混合装置; 以及向临床标本提供气动的气动装置。 气动装置包括可以进入测试收集装置的空气注射针和连接到空气注射针的空气传送通道。 混合装置包括在反应室内与试剂配置的磁性搅拌部件和向磁性搅拌部件提供扭矩的旋转装置。 旋转装置包括在旋转轴的一个方向上包括磁性的马达。
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42.发明授权비변형 고체표면을 선택적으로 광응답형 코팅막으로 개질하는 방법 및 광응답형 코팅막을 이용한 활성물질 고정화 방법 失效用于功能化选择性非改性固体表面的方法和用于在活性固体表面上固定活性材料的方法
公开(公告)号：KR101309617B1
公开(公告)日：2013-09-23
申请号：KR1020090126051
申请日：2009-12-17
Applicant: 한국전자통신연구원
CPC classification number: G01N33/54353 , B01J2219/00612 , B01J2219/00637 , B01J2219/00725
Abstract: 본 발명은 비변형 고체표면을 선택적으로 광응답형 코팅막으로 개질하는 방법 및 광응답형 코팅막을 이용한 활성물질 고정화 방법에 관한 것으로, 산화 또는 질화되지 않은 비변형 고체표면만을 수소로 개질시키는 단계; 수소로 개질된 비변형 고체표면에 광을 이용하여 EGPA 코팅막을 형성하는 단계; 상기 EGPA 코팅막의 아민 보호기 또는 아민염을 제거하여 EGA 코팅막을 형성하는 단계; 및 상기 EGA 코팅막을 이용하여 상기 비변형 고체표면상에 광에 응답하는 작용기를 갖는 코팅막을 형성하는 단계를 거쳐 비변형 고체표면만을 선택적으로 광응답형 코팅막으로 개질하고, 상기 개질된 비변형 고체표면에 활성물질을 접촉시키고 광을 조사하여 상기 활성물질을 고정시킨다.
선택적 개질, 광응답형 코팅막, 활성물질, 고정화-
公开(公告)号：KR1020130091132A
公开(公告)日：2013-08-16
申请号：KR1020120012429
申请日：2012-02-07
IPC: C07K16/18 , C12N15/13 , A61K39/395 , A61P35/00
Abstract: PURPOSE: Metriptase-specific human antibody is provided to be usefully used to diagnosis, prevention and treatment of cancer which is a disease related to the manifestation and be especially used as a kit for cancer diagnosis. CONSTITUTION: Human monoclonal antibody specific to matriptase protein or a fraction having immunological activity of the antibody comprises heavy chain complementarity determining regions (HCDR1) having an amino acid sequence of the sequence number 12, heavy chain that includes the heavy variable domain (V_H) which includes HCDR2 having an amino acid sequence of the sequence number 13 and HCDR3 having an amino acid sequence of the sequence number 14, light chain complementarity determining regions (HCDR1) having an amino acid sequence of the sequence number 16 and light chain having light variable domain (V_L) which includes LCDR2 having an amino acid sequence of the sequence number 17 and LCDR3 having an amino acid sequence of the sequence number 18.
Abstract translation: 目的：提供Metriptase特异性人抗体用于诊断，预防和治疗癌症，这是一种与表现相关的疾病，特别用作癌症诊断的试剂盒。 构成：具有对matriptase蛋白质或具有抗体免疫活性的级分的人单克隆抗体包括具有序列号12的氨基酸序列的重链互补决定区（HCDR1），重链包括重链可变结构域（V_H），重链可变区 包括具有序列号13的氨基酸序列的HCDR2和具有序列号14的氨基酸序列的HCDR3，具有序列号16的氨基酸序列的轻链互补决定区（HCDR1）和具有光可变结构域的轻链 （V_L），其包括具有序列号17的氨基酸序列的LCDR2和具有序列号18的氨基酸序列的LCDR3。
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公开(公告)号：KR1020130057720A
公开(公告)日：2013-06-03
申请号：KR1020110123605
申请日：2011-11-24
Applicant: 한국전자통신연구원
CPC classification number: B01D15/08 , A61K35/14 , B01L3/502753 , B01L2300/0681 , B01L2300/0825
Abstract: PURPOSE: An apparatus for pretreatment of blood, comprising an albumin removing part and an aggregation part, is provided to quickly remove albumin from whole blood with high sensitivity. CONSTITUTION: An apparatus for pretreatment of blood comprises an injection part(110), an albumin removing part(120), an aggregation part(130). The injection part is used for injecting a blood sample. The albumin removing part contains beads for adsorbing albumin to remove albumin from the blood sample. The aggregation part contains an aggregation reactant for forming a hemagglutination reactant. The apparatus further comprises a filter(140) for removing the hemagglutination reactant. A method for pretreatment of blood comprises: a step of removing albumin using the beads from a blood sample; and a step of aggregating blood cells in the blood sample using the aggregation reactant.
Abstract translation: 目的：提供一种包含白蛋白去除部分和凝集部分的血液预处理装置，以高灵敏度快速清除全血中的白蛋白。 构成：用于血液预处理的装置包括注射部分（110），白蛋白去除部分（120），聚集部分（130）。 注射部分用于注射血液样品。 白蛋白去除部分含有用于吸附白蛋白以从血液样品中除去白蛋白的珠子。 聚集部分包含用于形成血凝反应物的聚集反应物。 该装置还包括用于去除血细胞凝集反应物的过滤器（140）。 一种预处理血液的方法包括：使用来自血液样品的小珠除去白蛋白的步骤; 以及使用聚集反应物聚集血液样品中的血细胞的步骤。
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公开(公告)号：KR101211322B1
公开(公告)日：2012-12-11
申请号：KR1020110013514
申请日：2011-02-16
Abstract: 플렉서블질화갈륨발광다이오드제조방법및 이에의하여제조된플렉서블질화갈륨발광다이오드가제공된다. 본발명에따른플렉서블질화갈륨발광다이오드제조방법은실리콘기판상에질화갈륨발광다이오드소자층을적층하는단계; 상기소자층상에금속층을적층하여오믹(Ohmic) 컨택을형성하는단계; 상기금속층을포함하는상기질화갈륨발광다이오드의소자영역을실리콘희생기판으로부터분리하여, 플렉서블기판에전사시키는단계; 및상기소자층상에투명패시베이션층을코팅하는단계를포함하는것을특징으로하며, 본발명에따른플렉서블질화갈륨발광다이오드는플렉서블의가요성에기인하여, 종래의질화갈륨발광다이오드의한계로지적받았던기판의부정합, 고정성등을효과적으로극복할수 있다.
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Patent Agency Ranking
公开(公告)号：KR101179555B1
公开(公告)日：2012-09-05
申请号：KR1020080130964
申请日：2008-12-22
Applicant: 한국전자통신연구원
Abstract: 본 발명은 바이오 센서 칩에 관한 것으로, 표적 물질과 감지 물질 간의 상호 반응으로써 상기 표적 물질을 검출하는 센싱부와, 상기 센싱부와 전기적으로 연결된 기판 회로부와, 상기 표적 물질을 포함하는 용액성 물질을 상기 센싱부로 제공하는 채널부와, 그리고 상기 기판 회로부와 결합하여 상기 채널부 및 센싱부를 덮는 커버를 포함하는 것을 특징으로 한다.
센서, 바이오 센서, 실리콘 나노 채널, 모세관 현상-
公开(公告)号：KR101173981B1
公开(公告)日：2012-08-16
申请号：KR1020080120189
申请日：2008-11-29
Applicant: 한국전자통신연구원
Abstract: 본발명은바이오센서에관한것으로, 반도체기판상에감지물질이고정된복수개의단위센서를포함하는센싱부와, 상기감지물질과상호반응하는표적물질을포함하는용액성물질을상기센싱부로제공하여상기용액성물질과상기복수개의단위센서를상호접촉시키는채널부와, 상기센싱부와전기적으로결합되어외부장치와상기센싱부간의전기적신호의입출력을담당하는기판회로부와, 상기기판회로부를덮으며, 모세관현상을이용하여상기용액성물질을상기센싱부로제공하는복층구조의덮개를포함하는것을특징으로한다.
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公开(公告)号：KR1020120062327A
公开(公告)日：2012-06-14
申请号：KR1020100123542
申请日：2010-12-06
Applicant: 한국전자통신연구원
IPC: G01N33/53 , G01N33/487 , C12Q1/68
CPC classification number: G01N33/54366 , C12Q1/6825 , C12Q1/6834 , G01N33/487 , G01N33/5302 , G01N33/5308
Abstract: PURPOSE: A biosensor apparatus is provided to simply and quickly analyze result and to save the cost for producing and managing a sensor reader. CONSTITUTION: A biosensor apparatus comprises a capillary tube in which probe molecules are fixed on the surface of inner wall, and a liquid sample which contains target molecules and is filled in the capillary tube. A contact angle between the surface of inner wall and liquid sample is changed according to the specific binding between the probe molecules and target molecules. The capillary tube is formed of transparent materials. The probe molecules and target molecules are biotin and streptavidin, respectively.
Abstract translation: 目的：提供生物传感器设备，简单快速地分析结果，节省生产和管理传感器读取器的成本。 构成：生物传感器装置包括其中探针分子固定在内壁表面上的毛细管和含有靶分子并填充在毛细管中的液体样品。 根据探针分子和靶分子之间的特异性结合，改变内壁表面与液体样品之间的接触角。 毛细管由透明材料形成。 探针分子和靶分子分别是生物素和链霉亲和素。
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公开(公告)号：KR101140137B1
公开(公告)日：2012-05-02
申请号：KR1020090028884
申请日：2009-04-03
Applicant: 한국전자통신연구원
Abstract: 디포타슘 비스(p-설폰아토페닐)페닐 포스핀 및 상기 디포타슘 비스(p-설폰아토페닐)페닐 포스핀이 흡착된 금 나노입자를 포함하는 유기물질-금 나노입자의 컨쥬게이트를 이용한 용액 특성 평가 방법 및 평가 장치가 개시된다.
금 나노입자, 가역적 자기 조립, 흡광도, 알칼리 금속 이온, 열 감지-
公开(公告)号：KR1020110064906A
公开(公告)日：2011-06-15
申请号：KR1020090121682
申请日：2009-12-09
Applicant: 한국전자통신연구원
IPC: G01N33/53 , G01N33/545 , G01N33/569 , G01N33/553
CPC classification number: G01N33/54366 , B01L3/5027 , G01N33/56983 , G01N2800/12
Abstract: PURPOSE: A diagnosis kit for respiratory diseases is provided to enable easy and accurate diagnosis regardless of place. CONSTITUTION: A diagnosis kit for respiratory diseases comprises a substrate(100), an expiratory air collection unit(200), a microfluidic channel(300), and reaction unit(400). The expiratory air collection unit comprises a porous microbead(210) which is placed on a substrate for collecting materials contained in the expiratory air into the liquid phase. The microfluidic channel is connected to an expiratory air collection unit and transfers the collected liquid to the reaction unit. The surface of the porous microbead is treated using proteins to have hydrophilicity.
Abstract translation: 目的：提供呼吸系统疾病诊断工具，无论身处何地，都能轻松准确地诊断。 构成：用于呼吸系统疾病的诊断试剂盒包括底物（100），呼气空气收集单元（200），微流体通道（300）和反应单元（400）。 呼气空气收集单元包括多孔微珠（210），其放置在基底上，用于将包含在呼气空气中的物质收集到液相中。 微流体通道连接到呼气空气收集单元并将收集的液体传送到反应单元。 使用蛋白质处理多孔微珠的表面以具有亲水性。
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