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公开(公告)号：ZA883428B
公开(公告)日：1990-01-31
申请号：ZA883428
申请日：1988-05-16
Applicant: BASF AG
Inventor： DOERPER THOMAS , THOMAS DOERPER , MOELLER ACHIM , ACHIM MOELLER , HILLEN HEINZ , HEINZ HILLEN , KEILHAUER GERHARD , GERHARD KEILHAUER , EMLING FRANZ , FRANZ EMLING , DAUM LOTHAR , LOTHAR DAUM
IPC: A61K38/00 , A61P35/00 , C07K1/20 , C12N15/09 , C07K14/00 , C07K14/52 , C07K14/525 , C07K14/78 , C07K19/00 , C12P21/02 , C12R1/19 , C07K , C07H , C12P
Abstract: Tumor necrosis factor (TNF) produced from the TNF molecule by modification at the amino terminus are prepared as described and are suitable for controlling diseases.
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公开(公告)号：AU590861B2
公开(公告)日：1989-11-16
申请号：AU7452187
申请日：1987-06-19
Applicant: BASF AG
Inventor： SCHOLLMEIER KLAUS , MOELLER ACHIM , KOERWER WOLFGANG , DOERPER THOMAS , HILLEN HEINZ , DAUM LOTHAR , EMLING FRANZ , KEILHAUER GERHARD
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公开(公告)号：DK263588A
公开(公告)日：1988-11-17
申请号：DK263588
申请日：1988-05-13
Applicant: BASF AG
Inventor： DOERPER THOMAS , MOELLER ACHIM , HILLEN HEINZ , KEILHAUER GERHARD , EMLING FRANZ , DAUM LOTHAR
IPC: C12N15/09 , A61K38/00 , A61P35/00 , C07K1/20 , C07K14/00 , C07K14/52 , C07K14/525 , C07K14/78 , C07K19/00 , C12P21/02 , C12R1/19 , C07K13/00 , C12N15/00
Abstract: Tumor necrosis factor (TNF) produced from the TNF molecule by modification at the amino terminus are prepared as described and are suitable for controlling diseases.
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公开(公告)号：DK502988D0
公开(公告)日：1988-09-09
申请号：DK502988
申请日：1988-09-09
Applicant: BASF AG
Inventor： SCHOLLMEIER KLAUS , KREIMEYER ANDREAS , DAUM LOTHAR
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公开(公告)号：AU7999687A
公开(公告)日：1988-04-28
申请号：AU7999687
申请日：1987-10-21
Applicant: BASF AG
Inventor： SEITZ WERNER , DAUM LOTHAR , EMLING FRANZ , KEILHAUER GERHARD
IPC: A61K31/275 , A61K31/277 , A61P35/00
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Patent Agency Ranking
公开(公告)号：FI872635A
公开(公告)日：1987-12-21
申请号：FI872635
申请日：1987-06-12
Applicant: BASF AG
Inventor： SCHOLLMEIER KLAUS , MOELLER ACHIM , KOERWER WOLFGANG , DOERPER THOMAS , HILLEN HEINZ , DAUM LOTHAR , EMLING FRANZ , KEILHAUER GERHARD
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公开(公告)号：FI872635A0
公开(公告)日：1987-06-12
申请号：FI872635
申请日：1987-06-12
Applicant: BASF AG
Inventor： SCHOLLMEIER KLAUS , MOELLER ACHIM , KOERWER WOLFGANG , DOERPER THOMAS , HILLEN HEINZ , DAUM LOTHAR , EMLING FRANZ , KEILHAUER GERHARD
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公开(公告)号：ES2063350T3
公开(公告)日：1995-01-01
申请号：ES90906924
申请日：1990-05-04
Applicant: BASF AG
Inventor： LEMAIRE HANS-GEORG , HILLEN HEINZ , MOELLER ACHIM , DAUM LOTHAR , DOERPER THOMAS , SUBKOWSKI THOMAS
IPC: A61K35/22 , A61K38/00 , A61K38/17 , A61K38/19 , A61P7/00 , A61P7/02 , A61P7/04 , A61P11/00 , A61P19/00 , A61P19/02 , A61P19/08 , A61P25/00 , A61P29/00 , A61P31/04 , A61P37/00 , A61P37/02 , A61P37/08 , A61P43/00 , C07K1/18 , C07K1/22 , C07K7/08 , C07K14/00 , C07K14/435 , C07K14/47 , C07K14/525 , C07K14/715 , C07K16/18 , C07K15/14 , A61K35/12
Abstract: PCT No. PCT/EP90/00719 Sec. 371 Date Sep. 26, 1991 Sec. 102(e) Date Sep. 26, 1991 PCT Filed May 4, 1990 PCT Pub. No. WO90/13575 PCT Pub. Date Nov. 15, 1990.Novel proteins which have a molecular weight of about 42,000 daltons and have at the N terminus the amino acid sequence Xaa Thr Pro Tyr Ala Pro Glu Pro Gly Set Thr Cys Arg Leu Arg Glu where X is hydrogen, a phenylalanine residue (Phe) or the amino acid sequences Ala Phe, Val Ala Phe, Gln Val Ala Phe, Ala Gln Val Ala Phe, Pro Ala Gln Val Ala Phe or Leu Pro Ala Gln Val Ala Phe, and which are suitable for the treatment of diseases, are described.
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公开(公告)号：HU208162B
公开(公告)日：1993-08-30
申请号：HU374090
申请日：1990-05-04
Applicant: BASF AG
Inventor： LEMAIRE HANS-GEORG , HILLEN HEINZ , MOELLER ACHIM , DAUM LOTHAR , DOERPER THOMAS , SUBKOWSKI THOMAS
IPC: A61K35/22 , A61K38/00 , A61K38/17 , A61K38/19 , A61P7/00 , A61P7/02 , A61P7/04 , A61P11/00 , A61P19/00 , A61P19/02 , A61P19/08 , A61P25/00 , A61P29/00 , A61P31/04 , A61P37/00 , A61P37/02 , A61P37/08 , A61P43/00 , C07K1/18 , C07K1/22 , C07K7/08 , C07K14/00 , C07K14/435 , C07K14/47 , C07K14/525 , C07K14/715 , C07K16/18 , C07K15/04 , C07K15/14 , A61K37/00 , A61K35/12
Abstract: PCT No. PCT/EP90/00719 Sec. 371 Date Sep. 26, 1991 Sec. 102(e) Date Sep. 26, 1991 PCT Filed May 4, 1990 PCT Pub. No. WO90/13575 PCT Pub. Date Nov. 15, 1990.Novel proteins which have a molecular weight of about 42,000 daltons and have at the N terminus the amino acid sequence Xaa Thr Pro Tyr Ala Pro Glu Pro Gly Set Thr Cys Arg Leu Arg Glu where X is hydrogen, a phenylalanine residue (Phe) or the amino acid sequences Ala Phe, Val Ala Phe, Gln Val Ala Phe, Ala Gln Val Ala Phe, Pro Ala Gln Val Ala Phe or Leu Pro Ala Gln Val Ala Phe, and which are suitable for the treatment of diseases, are described.
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公开(公告)号：HUT58352A
公开(公告)日：1992-02-28
申请号：HU374090
申请日：1990-05-04
Applicant: BASF AG
Inventor： LEMAIRE HANS-GEORG , HILLEN HEINZ , MOELLER ACHIM , DAUM LOTHAR , DOERPER THOMAS , SUBKOWSKI THOMAS
IPC: A61K35/22 , A61K38/00 , A61K38/17 , A61K38/19 , A61P7/00 , A61P7/02 , A61P7/04 , A61P11/00 , A61P19/00 , A61P19/02 , A61P19/08 , A61P25/00 , A61P29/00 , A61P31/04 , A61P37/00 , A61P37/02 , A61P37/08 , A61P43/00 , C07K1/18 , C07K1/22 , C07K7/08 , C07K14/00 , C07K14/435 , C07K14/47 , C07K14/525 , C07K14/715 , C07K16/18 , C07K15/14 , A61K37/02
Abstract: PCT No. PCT/EP90/00719 Sec. 371 Date Sep. 26, 1991 Sec. 102(e) Date Sep. 26, 1991 PCT Filed May 4, 1990 PCT Pub. No. WO90/13575 PCT Pub. Date Nov. 15, 1990.Novel proteins which have a molecular weight of about 42,000 daltons and have at the N terminus the amino acid sequence Xaa Thr Pro Tyr Ala Pro Glu Pro Gly Set Thr Cys Arg Leu Arg Glu where X is hydrogen, a phenylalanine residue (Phe) or the amino acid sequences Ala Phe, Val Ala Phe, Gln Val Ala Phe, Ala Gln Val Ala Phe, Pro Ala Gln Val Ala Phe or Leu Pro Ala Gln Val Ala Phe, and which are suitable for the treatment of diseases, are described.
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