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143 records (took 0.025 seconds)

    42.
    发明专利
    未知

    公开(公告)号：AT217024T

    公开(公告)日：2002-05-15

    申请号：AT96900601

    申请日：1996-01-20

    Applicant: BASF AG

    Inventor： BALKENHOHL FRIEDHELM ,  DITRICH KLAUS ,  NUEBLING CHRISTOPH

    IPC: C12P13/02 ,  C12P41/00

    Abstract: A process for preparing optically active primary and secondary heteroatom-substituted amines from the corresponding racemates, which comprisesa) enantioselective acylation of a racemic heteroatom-substituted amine with an ester whose acid component carries a fluorine, nitrogen, phosphorus, oxygen or sulfur atom in the vicinity of the carbonyl carbon, in the presence of a hydrolase,b) separation of the mixture of optically active heteroatom-substituted amine and optically active acylated heteroatom-substituted amine to obtain one enantiomer of the heteroatom-substituted amine,c) if required isolation of the other enantiomer of the heteroatom-substituted amine from the acylated heteroatom-substituted amine by amide cleavage.

    44.
    发明专利
    未知

    公开(公告)号：PT850214E

    公开(公告)日：2000-09-29

    申请号：PT96931783

    申请日：1996-09-09

    Applicant: BASF AG

    Inventor： LADNER WOLFGANG ,  BALKENHOHL FRIEDHELM ,  DITRICH KLAUS

    IPC: C12M1/40 ,  B01J23/04 ,  C07B53/00 ,  C07B61/00 ,  C07C69/708 ,  C07C209/62 ,  C07C211/27

    Abstract: PCT No. PCT/EP96/03948 Sec. 371 Date Jan. 27, 1998 Sec. 102(e) Date Jan. 27, 1998 PCT Filed Sep. 9, 1996 PCT Pub. No. WO97/10201 PCT Pub. Date Mar. 20, 1997The present invention relates to a process for cleaving optically active amides to carboxylic acids and optically active amines with retention of the center of chirality, wherein the amides are hydrolyzed in the presence of a polyol or of an amino alcohol and of an alkali metal or alkaline earth metal hydroxide.

    45.
    发明专利
    未知

    公开(公告)号：ES2145485T3

    公开(公告)日：2000-07-01

    申请号：ES96931783

    申请日：1996-09-09

    Applicant: BASF AG

    Inventor： DITRICH KLAUS ,  BALKENHOHL FRIEDHELM ,  LADNER WOLFGANG

    IPC: C12M1/40 ,  B01J23/04 ,  C07B53/00 ,  C07B61/00 ,  C07C69/708 ,  C07C209/62 ,  C07C211/27

    Abstract: PCT No. PCT/EP96/03948 Sec. 371 Date Jan. 27, 1998 Sec. 102(e) Date Jan. 27, 1998 PCT Filed Sep. 9, 1996 PCT Pub. No. WO97/10201 PCT Pub. Date Mar. 20, 1997The present invention relates to a process for cleaving optically active amides to carboxylic acids and optically active amines with retention of the center of chirality, wherein the amides are hydrolyzed in the presence of a polyol or of an amino alcohol and of an alkali metal or alkaline earth metal hydroxide.

    46.
    发明专利
    未知

    公开(公告)号：DE59604901D1

    公开(公告)日：2000-05-11

    申请号：DE59604901

    申请日：1996-08-26

    Applicant: BASF AG

    Inventor： WETTERICH FRANK ,  WAGNER OLIVER ,  EICKEN KARL ,  DITRICH KLAUS ,  AMMERMANN EBERHARD ,  LORENZ GISELA ,  STRATHMANN SIEGFRIED

    IPC: C07C269/04 ,  A01N47/12 ,  C07C269/06 ,  C07C271/22

    Abstract: PCT No. PCT/EP96/03755 Sec. 371 Date Feb. 17, 1998 Sec. 102(e) Date Feb. 17, 1998 PCT Filed Aug. 26, 1996 PCT Pub. No. WO97/08138 PCT Pub. Date Mar. 6, 1997Carbamoylcarboxamides of the general formula I (R1=unsubstituted or substituted alkyl, alkenyl, alkynyl; R2=hydrogen, halogen, cyano, nitro, or unsubstituted or substituted alkyl, alkoxy, alkylthio, or an unsubstituted or substituted phenyl group which is bonded via oxygen or sulfur) and compositions comprising them, processes for their preparation, and the use of the compounds I and of the compositions.

    Enzyme-catalyzed racemic cleavage of primary amines
    49.
    发明专利
    Enzyme-catalyzed racemic cleavage of primary amines 未知

    公开(公告)号：AU5516499A

    公开(公告)日：2000-03-14

    申请号：AU5516499

    申请日：1999-08-13

    Applicant: BASF AG

    Inventor： NUBLING CHRISTOPH ,  DITRICH KLAUS ,  DULLY CHRISTIAN

    IPC: C07C213/08 ,  C07C217/08 ,  C12P13/02 ,  C12P41/00

    Abstract: The present invention relates to a process for resolving racemates of alkoxy-substituted primary amines by reacting with an ester in the presence of a lipase and subsequently separating the optically active amide which is formed from the unreacted optically active amine. This is followed where appropriate by hydrolysis of the optically active amide, separation of the optically active amine produced thereby from the acid from which the ester is derived, racemization and recycling of the unwanted enantiomer of the amine, and esterification and recycling of the acid.

    ENZYME-CATALYZED RACEMIC CLEAVAGE OF PRIMARY AMINES
    50.
    发明专利
    ENZYME-CATALYZED RACEMIC CLEAVAGE OF PRIMARY AMINES 未知

    公开(公告)号：CA2341345A1

    公开(公告)日：2000-03-02

    申请号：CA2341345

    申请日：1999-08-13

    Applicant: BASF AG

    Inventor： DULLY CHRISTIAN ,  DITRICH KLAUS ,  NUBLING CHRISTOPH

    IPC: C07C213/08 ,  C07C217/08 ,  C12P13/02 ,  C12P41/00

    Abstract: The invention relates to a method for the racemic cleavage of alkoxy- substituted primary amines by reaction with an ester in the presence of a lipase and subsequent separation of the resulting optically active amide fro m the optically active unreacted amine. This is possibly followed by hydrolysi s of the optically active amide, separation of the resulting optically active amine from the acid at the origin of the ester, racemization and recirculati on of the undesirable enantiomer of the amine and esterification and recirculation of the acid.

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