THE PRODUCTION OF SOLID DRUG FORMS
    49.
    发明专利

    公开(公告)号:CA2209943A1

    公开(公告)日:1998-01-23

    申请号:CA2209943

    申请日:1997-07-08

    Applicant: BASF AG

    Abstract: Solid drug forms are produced by mixing and melting at least one pharmacologically acceptable polymeric binder and at least one pharmaceutical active ingredient, with or without conventional pharmaceutical additives, in the absence of a solvent to give a plastic mixture and shaping the mixture to the required drug form by extrusion, where the shaping takes place in two steps, with the extrudate being broken into shaped articles in a first step, and these shaped articles being rounded off in a second step in the plastic state.

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