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公开(公告)号：CA2005281A1
公开(公告)日：1990-06-12
申请号：CA2005281
申请日：1989-12-12
Applicant: BASF AG
Inventor： BOEHM HANS-JOACHIM , DAUM LOTHAR , HAUPT ANDREAS , SCHMIED BERNHARD , WALKER NIGEL , ZECHEL JOHANN-CHRISTIAN
IPC: A61K38/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07K1/04 , C07K7/06 , C07K7/08 , C07K7/56 , C07K7/64 , C07K14/52 , C07K14/525 , A61K38/02 , A61K38/08
Abstract: - 33 - O. Z . 0050/40383 Peptides of the formula X-A-Asn-B-Y, where A, B, X and Y are defined in the description, and the preparation thereof are described. The novel peptides are suitable for controlling diseases.
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公开(公告)号：CA2005051A1
公开(公告)日：1990-06-12
申请号：CA2005051
申请日：1989-12-11
Applicant: BASF AG
Inventor： BOEHM HANS-JOACHIM , DAUM LOTHAR , HAUPT ANDREAS , SCHMIED BERNHARD , WALKER NIGEL , ZECHEL JOHANN-CHRISTIAN
IPC: A61K38/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07K1/04 , C07K7/06 , C07K7/08 , C07K7/56 , C07K7/64 , C07K14/52 , C07K14/525 , A61K38/08 , A61K38/10 , A61K38/12 , A61K38/19 , C07K7/50
Abstract: Peptides of the formula X-A-Gly-B-Y, where A, B, X and Y are defined in the description, and the preparation thereof are described. The novel peptides are suitable for controlling diseases.
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公开(公告)号：SK14102001A3
公开(公告)日：2002-07-02
申请号：SK14102001
申请日：2000-03-29
Applicant: BASF AG
Inventor： ZECHEL JOHANN-CHRISTIAN , KLING ANDREAS , GENESTE HERVE , LANGE UDO , LAUTERBACH ARNULF , GRAEF CLAUDIA ISABELLA , SUBKOWSKI THOMAS , SADOWSKI JENS , HORNBERGER WILFRIED
IPC: A61K31/505 , A61K45/00 , A61K45/06 , A61P3/14 , A61P7/02 , A61P9/10 , A61P9/12 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/08 , A61P19/10 , C07D239/36 , A61P29/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , C07D239/34 , C07D239/60 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D239/46 , C07D403/04
Abstract: The invention relates to novel compounds which bind to integrin receptors, to their preparation, to their use as integrin receptor ligands and for treating diseases, to pharmaceutical preparations comprising these compounds, and to pharmaceutical preparations comprising at least one other active compound.
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公开(公告)号：BR0009739A
公开(公告)日：2002-04-09
申请号：BR0009739
申请日：2000-03-29
Applicant: BASF AG
Inventor： ZECHEL JOHANN-CHRISTIAN , KLING ANDREAS , GENESTE HERVE , LANGE UDO , LAUTERBACH ARNULF , GRAEF CLAUDIA ISABELLA , SUBKOWSKI THOMAS , SADOWSKI JENS , HORNBERGER WILFRIED
IPC: C07D239/36 , A61K31/505 , A61K45/00 , A61K45/06 , A61P3/14 , A61P7/02 , A61P9/10 , A61P9/12 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/08 , A61P19/10 , A61P29/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , C07D239/34 , C07D239/60 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/14 , C07D417/12 , C07D417/14
Abstract: The invention relates to novel compounds which bind to integrin receptors, to their preparation, to their use as integrin receptor ligands and for treating diseases, to pharmaceutical preparations comprising these compounds, and to pharmaceutical preparations comprising at least one other active compound.
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公开(公告)号：TR200102913T2
公开(公告)日：2002-01-21
申请号：TR200102913
申请日：2000-03-28
Applicant: BASF AG
Inventor： HILLEN HEINZ , SCHMIDT MARTIN , MACK HELMUT , SEITZ WERNER , HAUPT ANDREAS , ZECHEL JOHANN-CHRISTIAN , KLING ANDREAS
IPC: A61K38/00 , A61K38/55 , A61P1/04 , A61P1/18 , A61P5/14 , A61P7/02 , C12N9/99 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/12 , A61P15/00 , A61P17/02 , A61P19/02 , A61P21/04 , A61P25/00 , A61P25/28 , A61P29/00 , A61P37/02 , C07B43/00 , C07D401/12 , C07D409/12 , C07K5/06 , C07K5/062 , C07K5/065 , C07K5/068 , C07K5/072 , C07K5/078 , A61K38/05
Abstract: Peptide substances, their preparation and their use as complement inhibitors are described. These are in particular substances having a guanidine or amidine radical as a terminal group. In particular, inhibitors of the complement proteases C1s and C1r are described.
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Patent Agency Ranking
公开(公告)号：NO20015237L
公开(公告)日：2001-12-21
申请号：NO20015237
申请日：2001-10-26
Applicant: BASF AG
Inventor： ZECHEL JOHANN-CHRISTIAN , KLING ANDREAS , GENESTE HERVE , LANGE UDO , LAUTERBACH ARNULF , GRAEF CLAUDIA ISABELLA , SUBKOWSKI THOMAS , HORNBERGER WILFRIED
IPC: C12N9/99 , A61K31/27 , A61K31/381 , A61K31/421 , A61K31/426 , A61K31/4406 , A61K31/443 , A61K31/4439 , A61K38/00 , A61K45/00 , A61K45/06 , A61P3/10 , A61P3/14 , A61P7/02 , A61P9/00 , A61P9/04 , A61P9/08 , A61P9/10 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/02 , A61P19/08 , A61P19/10 , A61P29/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , A61P43/00 , C07C275/42 , C07D207/34 , C07D213/56 , C07D249/14 , C07D263/34 , C07D263/48 , C07D277/20 , C07D277/48 , C07D277/56 , C07D307/68 , C07D333/38 , C07D333/40 , C07D401/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07K5/02 , C07K5/023 , A61K38/06
Abstract: The invention relates to new compounds which bind to integrin receptors, as well as to their production, their use as integrin receptor antagonists and for the treatment of diseases, pharmaceutical preparations containing said compounds and pharmaceutical preparations containing at least one other active compound.
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公开(公告)号：NO20014961A
公开(公告)日：2001-11-07
申请号：NO20014961
申请日：2001-10-12
Applicant: BASF AG
Inventor： ZECHEL JOHANN-CHRISTIAN , KLING ANDREAS , GENESTE HERVE , LANGE UDO , LAUTERBACH ARNULF , GRAEF CLAUDIA ISABELLA , SUBKOWSKI THOMAS , SADOWSKI JENS , HORNBERGER WILFRIED
IPC: C07D239/36 , A61K31/505 , A61K45/00 , A61K45/06 , A61P3/14 , A61P7/02 , A61P9/10 , A61P9/12 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/08 , A61P19/10 , A61P29/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , C07D239/34 , C07D239/60 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D233/54
CPC classification number: C07D405/14 , A61K45/06 , C07D239/34 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/04 , C07D409/14 , C07D417/12 , C07D417/14
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公开(公告)号：DE19948269A1
公开(公告)日：2001-04-12
申请号：DE19948269
申请日：1999-10-06
Applicant: BASF AG
Inventor： ZECHEL JOHANN-CHRISTIAN , SUBKOWSKI THOMAS , KLING ANDREAS , LANGE UDO , LAUTERBACH ARNULF , GRAEF CLAUDIA ISABELLA , GENESTE HERVE , HORNBERGER WILFRIED
IPC: A61K38/00 , A61K45/06 , C07D263/34 , C07D277/48 , C07D307/68 , C07D333/38 , C07D409/12 , C07D413/12 , C07D417/12 , C07K5/02 , C07K5/08 , A61K38/06 , A61K45/00 , C07C233/00 , C07K5/097
Abstract: Compounds (I) and their salts, prodrugs, enantiomers and tautomers are new. Compounds of formula A-E-G-L (I) and their salts, prodrugs, enantiomers and tautomers are new. L = N(R )-CH(R )-(CHR )a-T; T = COOH or a group that hydrolyzes to form COOH; R = e.g. H or NHSO2R ; R = H or -(CH2)b-(X)c-R ; a, c = 0 or 1; b = 0-3; X = e.g. -SO2-, -S-, -O-, -CO- or -O-CO-; R , R = e.g. optionally substituted 1-6C alkyl; R = e.g. H or optionally substituted 1-4C alkyl; G = N(R )-(CH(CH2)dR )-CO; R = e.g. H, OH or optionally substituted 1-4C alkyl; R = e.g. H or optionally substituted 1-4C alkyl; d = 0-2; E = (NH)g-(CH2)f-Q-(CH2)e-CO; f, g = 0 or 1; e = 0-2; Q = optionally substituted heteroaryl; A = e.g. uracil-5-yl, 2-(1-pyrrolinyl), 2-(3,4,5,6-tetrahydropyridinyl) or 2-(4,5-dihydroimidazol-5-one). The full definition is given in the DEFINITION (Full Definition) Field.
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公开(公告)号：AU4551500A
公开(公告)日：2000-11-17
申请号：AU4551500
申请日：2000-04-17
Applicant: BASF AG
Inventor： KLING ANDREAS , LANGE UDO , LAUTERBACH ARNULF , GENESTE HERVE , SUBKOWSKI THOMAS , ZECHEL JOHANN-CHRISTIAN , GRAEF CLAUDIA ISABELLA , HORNBERGER WILFRIED
IPC: C12N9/99 , A61K31/27 , A61K31/381 , A61K31/421 , A61K31/426 , A61K31/4406 , A61K31/443 , A61K31/4439 , A61K38/00 , A61K45/00 , A61K45/06 , A61P3/10 , A61P3/14 , A61P7/02 , A61P9/00 , A61P9/04 , A61P9/08 , A61P9/10 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/02 , A61P19/08 , A61P19/10 , A61P29/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , A61P43/00 , C07C275/42 , C07D207/34 , C07D213/56 , C07D249/14 , C07D263/34 , C07D263/48 , C07D277/20 , C07D277/48 , C07D277/56 , C07D307/68 , C07D333/38 , C07D333/40 , C07D401/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07K5/02 , C07K5/023 , A61K38/04 , A61K31/33
Abstract: The invention relates to new compounds which bind to integrin receptors, as well as to their production, their use as integrin receptor antagonists and for the treatment of diseases, pharmaceutical preparations containing said compounds and pharmaceutical preparations containing at least one other active compound.
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公开(公告)号：AU4112900A
公开(公告)日：2000-11-14
申请号：AU4112900
申请日：2000-03-29
Applicant: BASF AG
Inventor： ZECHEL JOHANN-CHRISTIAN , KLING ANDREAS , GENESTE HERVE , LANGE UDO , LAUTERBACH ARNULF , GRAEF CLAUDIA ISABELLA , SUBKOWSKI THOMAS , SADOWSKI JENS , HORNBERGER WILFRIED
IPC: C07D239/36 , A61K31/505 , A61K45/00 , A61K45/06 , A61P3/14 , A61P7/02 , A61P9/10 , A61P9/12 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/08 , A61P19/10 , A61P29/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , C07D239/34 , C07D239/60 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/14 , C07D417/12 , C07D417/14
Abstract: The invention relates to novel compounds which bind to integrin receptors, to their preparation, to their use as integrin receptor ligands and for treating diseases, to pharmaceutical preparations comprising these compounds, and to pharmaceutical preparations comprising at least one other active compound.
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