Abstract:
PURPOSE: A novel Enterococcus faecalis CRNB-A3(KCTC 11930 BP) strain with saponin decomposition ability is provided to prepare ginseng and red ginseng fermentations with new efficacy. CONSTITUTION: An Enterococcus faecalis CRNB-A3(KCTC 11930 BP) strain has a saponin converting ability. Saponin Rb2 is converted into other ginsenoside using the strain. Ginseng is fermented by inserting the strain and fermenting at 20-50 Deg. C. for 20-120 hours. A health functional food contains the fermented ginseng as a raw material. The health functional food is manufactured in the form of a liquid phase formulation, candy, gum, paste, snack, and powder. A pharmaceutical composition for preventing or treating inflammation, allergy, cancer, impotency, hypertension, hyperlipidemia, thrombosis, and aging contains the fermented ginseng.
Abstract:
본 발명은 5,8-디메톡시-1,4-나프토퀴논 (5,8-Dimethxy-1,4-naphthoquinone, DMNQ) 의 유도체인 2-치환-5,8-디메톡시-1,4-나프토퀴논(2-substituted-5,8-dimethoxy-1,4-naphthoquinone) 화합물에 관한 것으로 상기 화합물은 혈소판 유래 성장인자(platelet derived growth factor, PDGF)를 억제함으로써 심혈관 질환의 예방 및 치료용 조성물로 유용하게 이용될 수 있다.
Abstract:
본 발명은 참당귀에서 분리된 (+)-데쿠르시놀(decursinol)의 구조이성체인 (8s)-8-하이드록시-7,7-디메틸-8,9-디하이드로피라노 [2,3-g] 쿠마린((8s)-8-hydroxy-7,7-dimethyl-8,9-dihydropyrano [2,3-g] coumarin)과 (6s)-6-하이드록시-7,7-디메틸-5,6-디하이드로피라노[3,2-f]쿠마린((6s)-6-hydroxy-7,7-dimethyl-5,6-dihydropyrano[3,2-f]coumarin)을 제조 및 합성한 후 이를 다시 전구체로 한 신규 구조의 (+)-데쿠르신-구조이성체 합성 유도체 화합물들은 EoL-1 세포에서 진드기에 의해 유도된 아토피성 피부염증 반응을 나타내는 MCP-1, IL-6 및 IL-8의 분비량을 효과적으로 억제함을 확인함으로써, 이를 포함하는 조성물은 아토피성 피부염 질환의 예방 및 치료를 위한 약학 조성물 및 건강기능식품으로 유용하게 이용될 수 있다. 참당귀, (+)-데쿠르시놀(decursinol), 아토피성 피부염
Abstract:
본 발명은 고온고압 제조방법을 이용하여 제조된 흑삼 뿌리로부터 추출된 추출물을 유효성분으로 함유하는 조성물에 관한 것으로, 상세하게는 본 발명의 조성물은 뛰어난 고병원성 조류 인플루엔자 바이러스(highly pathogenic avian influenza)에 대한 억제 효과를 나타내므로, 고병원성 조류 인플루엔자 바이러스 감염증의 예방 및 치료용 약학조성물 및 건강기능식품으로 유용하게 이용될 수 있다. 흑삼, 고병원성 조류 인플루엔자 바이러스
Abstract:
PURPOSE: A (+)-decursin-structural isomer synthetic derivative compound of novel structure is provided to suppress MCP-1, IL-16 and IL-18 secretion and to treat atopic dermatitis. CONSTITUTION: A (+)-decursin-structural isomer synthetic derivative compound of novel structure is denoted by general formula I or II. A pharmaceutical composition for preventing and treating atopic dermatitis contains (+)-decursin-structural isomer or pharmaceutically acceptable salt as an active ingredient. A health food for preventing and treating atopic dermatitis contains the (+)-decursin-structural isomer synthetic derivative compound or pharmaceutically acceptable salt as an active ingredient. The health food is used in the form of powder, granule, tablet, capsule or beverage.
Abstract:
A composition for preventing and treating highly pathogenic avian influenza virus is provided to have suppression effect to highly pathogenic avian influenza virus by using an extract isolated from Panax ginseng. A method for producing a composition for preventing and treating highly pathogenic avian influenza virus comprises: a step of producing a Panax ginseng; a step of mixing the Panax ginseng with water in a mass ratio of 1:3-7, and maintaining at room temperature for 3-7 hours; a step of adding water containing purified water, low alcohol of C1-4, or their mixture solvent in a mass ratio of 1:5-20; a step of extracting for 2-8 hours one to five times; and a step of cooling, filtering and concentrating the extract.