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公开(公告)号：KR101395875B1
公开(公告)日：2014-06-19
申请号：KR1020120128761
申请日：2012-11-14
Applicant: 한국식품연구원
Abstract: The present invention relates to prebiotics containing extracts of persimmon leaves for promoting probiotic bacteria proliferation and suppressing growth of pathogenic bacteria. According to the present invention, as a water extract of the persimmon leaves is treated to promote the proliferation of probiotic bacteria and an ethanol extract of the persimmon leaves is treated to suppress growth of intestinal pathogenic bacteria, the prebiotics containing the extracts of persimmon leaves can control the growth of both probiotic bacteria and pathogenic bacteria. The extracts of persimmon leaves also can have an antioxidant effect by having a superior ability in electron donation.
Abstract translation: 本发明涉及含有促进益生菌增殖并抑制致病菌生长的柿叶提取物的益生元。 根据本发明，对柿子的水提取物进行处理以促进益生菌的增殖，并且对柿子叶的乙醇提取物进行处理以抑制肠道致病菌的生长，含有柿叶提取物的益生元可以 控制益生菌和病原菌的生长。 通过在电子供体中具有优越的能力，柿叶的提取物也可以具有抗氧化作用。
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52.发明公开바실러스 서브틸리스 인아쿠오소럼 아종(Bacillus subtilis subsp. inaquosorum) 또는 바실러스 서브틸리스 인아쿠오소럼 아종(Bacillus subtilis subsp. inaquosorum)에 의한 콩 발효물을 유효성분으로 포함하는 항알레르기성 조성물 有权包含BACILLUS SUBTILIS SUBSP的抗过敏组合物。 使用这些替代品的大豆大豆的不育或物质
公开(公告)号：KR1020140053676A
公开(公告)日：2014-05-08
申请号：KR1020120119897
申请日：2012-10-26
Applicant: 한국식품연구원
Abstract: The present invention relates to an anti-allergic composition comprising Bacillus subtilis subsp. Inaquosorum or a substance of fermented soybean using the same as an active ingredient. According to the present invention, the substance of fermented soybean using Bacillus subtilis subsp. Inaquosorum has excellent effect of promoting cell reaction of Th1 and inhibiting cell reaction of Th2 and thus is capable of balancing Th1/Th2 immune responses.
Abstract translation: 本发明涉及一种抗过敏组合物，其包含枯草芽孢杆菌 发酵大豆或使用其作为活性成分的发酵大豆的物质。 根据本发明，使用枯草芽孢杆菌亚种的发酵大豆的物质 不饱和酸钠具有促进Th1细胞反应和抑制Th2细胞反应的极好作用，因此能平衡Th1 / Th2免疫反应。
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53.发明公开바실러스 아밀로리퀴페시언스 플란타럼 아종(Bacillus amyloliquefaciens subsp. plantarum) 또는 바실러스 아밀로리퀴페시언스 플란타럼 아종(Bacillus amyloliquefaciens subsp. plantarum)에 의한 콩 발효물을 유효성분으로 포함하는 항알레르기성 조성물 有权包含BACILLUS AMYLOLIQUEFACIENS SUBSP的抗过敏组合物。 使用这些替代品的大豆大豆的植物或物质
公开(公告)号：KR1020140053675A
公开(公告)日：2014-05-08
申请号：KR1020120119896
申请日：2012-10-26
Applicant: 한국식품연구원
Abstract: The present invention relates to an anti-allergic composition which comprises Bacillus amyloliquefaciens subsp. plantarum or a fermented soybean substance using Bacillus amyloliquefaciens subsp. plantarum as an active ingredient. The Bacillus amyloliquefaciens subsp. plantarum or the fermented soybean substance using Bacillus amyloliquefaciens subsp. plantarum of the present invention is excellent for promoting Th1 cellular response and inhibiting Th2 cellular response, thereby can adjust balance of Th1/Th2 immune response.
Abstract translation: 本发明涉及一种抗过敏组合物，其包含解淀粉芽孢杆菌亚种 植物油或使用解淀粉芽孢杆菌亚种的发酵大豆物质。 植物原料作为活性成分。 解淀粉芽孢杆菌亚种 植物油或使用解淀粉芽孢杆菌亚种的发酵大豆物质。 本发明的植物乳对于促进Th1细胞反应和抑制Th2细胞应答是极好的，从而可以调节Th1 / Th2免疫应答的平衡。
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公开(公告)号：KR1020130133609A
公开(公告)日：2013-12-09
申请号：KR1020120057005
申请日：2012-05-29
Applicant: 한국식품연구원
CPC classification number: A61K36/39 , A23K10/30 , A23L33/105 , A23V2002/00 , A23V2200/304 , A61K8/97 , A61Q19/00 , Y10S514/826
Abstract: The present invention relates to a composition containing a Pharbitis nil Choisy extract as an active ingredient and provides an anti-allergy composition, an anti-histaminic composition, and an anti-inflammatory composition. The composition of the present invention has excellent activities of inhibiting IL-4 generation, histamine secretion or degranulation, beta-hexosaminidase release, and COX-2. The present invention provides detailed mechanisms of anti-allergy materials derived from natural products and foods.
Abstract translation: 本发明涉及一种含有作为活性成分的无选择性石ic萃取物的组合物，并提供抗过敏组合物，抗组胺组合物和抗炎组合物。 本发明的组合物具有抑制IL-4产生，组胺分泌或脱粒，β-己糖胺酶释放和COX-2的优异活性。 本发明提供了衍生自天然产物和食品的抗过敏材料的详细机理。
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55.发明授权에드워드 타다, 스트랩토코커스 이니에 및 우결핵균에대한 특수면역단백질을 공유하는 계란생산방법 및 상기방법으로 생산된 계란, 난황 및 상기 항-혼합균특수면역단백질을 함유한 양어사료 失效에드워드타다，스트랩토코커스이니에및우결핵균에대한특수역단백질을을유하하계란생산방법및상기방법으로생산된계란，난황및상기항 - 혼합균특수수역을함한양한양한어어료료
公开(公告)号：KR100423551B1
公开(公告)日：2004-03-18
申请号：KR1020010035945
申请日：2001-06-22
Applicant: 한국식품연구원
IPC: A61K39/40
Abstract: PURPOSE: A Method for the production of an egg containing anti-Edwardsiella tarda IgY, anti-Streptococcus iniae IgY and Mycobacterium bovis IgY simultaneously, an egg produced thereby and a fish feed containing specific IgY thereof are provided. The produced egg and fish feed have excellent prevention effect on a flatfish disease. CONSTITUTION: An emulsion containing Edwardsiella tarda IgY, anti-Streptococcus iniae IgY, Mycobacterium bovis IgY and aluminium oxide in ratio of 3.0:3.0:1.0:3.0 is inoculated into a chicken in the amount of 1.0ml one time, and then, from a second time, the above emulsion and an adjuvant(ISA25) are inoculated together thereinto in the amount of 1.0ml at intervals of 2 weeks to produce an egg containing specific IgY. Egg yolk is then put up in a vessel, stirred in the equal amount of alkali ion water(pH 10.0), left alone for a specified period of time and then the supernatant is ultra-filtrated and freeze-dried after removing a fat layer floated on the upper layer to produce soluble IgY powder.
Abstract translation: 目的：提供一种同时生产含抗爱德华兹氏艾美尔球虫IgY，抗链球菌IgY和牛分枝杆菌IgY的蛋，由此产生的蛋和含有特定IgY的鱼饲料的方法。 生产的鸡蛋和鱼饲料对flat鱼疾病具有极好的预防效果。 构成：将含有比率为3.0:3.0:1.0:3.0的爱德华氏菌爱德华氏菌IgY，抗茵链球菌IgY，牛分枝杆菌IgY和氧化铝的乳剂一次接种到鸡1.0ml中，然后从 第二次以2周的间隔将上述乳剂和佐剂（ISA25）以1.0ml的量接种在其中，以产生含有特异性IgY的鸡蛋。 然后将蛋黄放入容器中，在等量的碱离子水（pH10.0）中搅拌，静置一段特定时间，然后将上清液超滤并在除去漂浮的脂肪层后冷冻干燥 在上层产生可溶性IgY粉末。
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Patent Agency Ranking
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公开(公告)号：KR101890017B1
公开(公告)日：2018-08-20
申请号：KR1020150149647
申请日：2015-10-27
Applicant: 한국식품연구원
IPC: A61K36/738 , A61K36/539 , A23L1/30 , A61K8/97 , A61Q19/00
Abstract: 본발명은영실및 황금추출물을유효성분으로포함하는 Th2-매개면역질환의예방, 개선, 또는치료용조성물에관한것이다. 영실및 황금은부작용이거의없고저렴한생산비용과사용의편의성을제공하는천연물소재이므로, 영실및 황금추출물을유효성분으로포함하는조성물은 Th2-매개면역질환의예방, 개선, 또는치료를위한치료제, 건강기능성식품, 및화장품의개발에유용하게이용될수 있을것이다.
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公开(公告)号：KR101843573B1
公开(公告)日：2018-03-30
申请号：KR1020160160179
申请日：2016-11-29
Applicant: 한국식품연구원
IPC: A61K36/73 , A23L33/105 , A61K8/97 , A61Q19/00
Abstract: 본발명은효소가처리된영실추출물을유효성분으로포함하는, Th2-매개면역질환의예방또는치료용조성물에관한것이다. 본발명에따른조성물은효소처리영실추출물을유효성분으로포함함으로써, 영실추출물의항알레르기효능을극대화할수 있다. 구체적으로, 본발명자들은 OVA로면역시킨마우스의비장세포에효소처리영실추출물을처리한결과효소를처리하지않은영실추출물에비하여 IL-4 생성억제활성이현저하게증진되며,에서효소처리영실추출물의경구투여에의해 OVA로면역시킨마우스의혈중 IgE 함량이현저히감소하는것을확인하였다. 또한, 천연물인영실을이용하므로생체친화적이고안정성이우수한장점이있으므로, 본발명에따른조성물은 Th2-매개면역질환의예방, 개선, 또는치료를위한안전한치료제, 건강기능성식품, 및화장품등의개발에유용하게이용될수 있을것으로기대된다.
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公开(公告)号：KR1020170138624A
公开(公告)日：2017-12-18
申请号：KR1020160070488
申请日：2016-06-07
Applicant: 한국식품연구원
Abstract: 데친버섯및 데친오징어의혼합물에간장, 야채육수, 정제수, 및설탕을포함하는조미액을가하여조미하는단계를포함하는, 버섯및 오징어를포함하는조림식품의제조방법에관한것이다. 본발명의버섯및 오징어를포함하는조림식품의제조방법을이용하면, 향, 맛, 식감이뛰어나우수한상품성을나타내는버섯및 오징어를포함하는조림식품을제조할수 있으므로, 버섯및 오징어의소비증대및 이들을이용한가공제품의품질향상에크게이바지할수 있을것이다.
Abstract translation: 水煮蘑菇和煮鱿鱼的混合物本发明涉及一种酱油，蔬菜肉汤，纯净水，和含有蘑菇和乌贼调味包括的步骤煮沸食品的制造方法落入含糖调料。 用含有本发明中，风味，口感蘑菇和鱿鱼，因为它可以制造一个煮食品质地优良包括蘑菇和显示良好的商业价值鱿鱼煮食品的制造方法，蘑菇和鱿鱼的消耗增加，而且这些 这将大大有助于提高加工产品的质量。
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60.发明公开
公开(公告)号：KR1020170068382A
公开(公告)日：2017-06-19
申请号：KR1020160160179
申请日：2016-11-29
Applicant: 한국식품연구원
IPC: A61K36/73 , A23L33/105 , A61K8/97 , A61Q19/00
CPC classification number: A61K36/73 , A23L33/105 , A23V2002/00 , A23V2200/324 , A23V2300/14 , A61K8/97 , A61Q19/00
Abstract: 본발명은효소가처리된영실추출물을유효성분으로포함하는, Th2-매개면역질환의예방또는치료용조성물에관한것이다. 본발명에따른조성물은효소처리영실추출물을유효성분으로포함함으로써, 영실추출물의항알레르기효능을극대화할수 있다. 구체적으로, 본발명자들은 OVA로면역시킨마우스의비장세포에효소처리영실추출물을처리한결과효소를처리하지않은영실추출물에비하여 IL-4 생성억제활성이현저하게증진되며,에서효소처리영실추출물의경구투여에의해 OVA로면역시킨마우스의혈중 IgE 함량이현저히감소하는것을확인하였다. 또한, 천연물인영실을이용하므로생체친화적이고안정성이우수한장점이있으므로, 본발명에따른조성물은 Th2-매개면역질환의예방, 개선, 또는치료를위한안전한치료제, 건강기능성식품, 및화장품등의개발에유용하게이용될수 있을것으로기대된다.
Abstract translation: 本发明涉及用于预防或治疗Th2介导的免疫疾病的组合物，其包含酶处理的精神提取物作为活性成分。 该组合物根据本发明，通过包括酶处理Youngsil提取物作为活性成分的一种可以最大限度地发挥抗过敏Youngsil提取物的功效。 具体而言，本发明人发现，用OVA和IL-4免疫的小鼠的脾细胞产生的抑制活性相比增加Youngsil提取物不与所述酶处理Youngsil提取物处理的结果酶处理显著，酶处理Youngsil从提取 已证实口服给予OVA免疫的小鼠血液中IgE的量显着降低。 此外，生物相容的，因此使用它是一种天然产品Yeongsil优异的稳定性的优点，根据本发明的组合物是一种安全的药物，用于预防，改善，或治疗Th2-介导的免疫疾病的健康功能性食品和化妆品的开发。 预计将对此有用
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