公开(公告)号：DE3309159A1

公开(公告)日：1984-09-20

申请号：DE3309159

申请日：1983-03-15

Applicant: BASF AG

Inventor： GEHRKEN HENNING-PETER DR ,  ERNST HANSGEORG DR ,  PAUST JOACHIM DR

IPC: C07D311/58 ,  C07D311/72

Abstract: Novel optically active chroman derivatives of the general formulae Ia and Ib (Ia) (Ib) where R1, R2, R3 and R4 are each hydrogen or alkyl and X is -OH, -O-CO-alkyl, -O-alkyl, -O-tosyl, -O-mesyl, -O-benzenesulfonyl, Cl, Br or I, are prepared by a process in which (a) the racemate of the formula I' (I') is esterified in the side chain with a carboxylic acid and then acylated with an optically active carboxylic acid halide of the general formula III (III) or with the corresponding carboxylic anhydride, to give a chroman derivative IV (IV) or (b) the racemate I' is esterified in the side chain with the carboxylic acid from which III is derived, and, if required, the resulting ester is acylated with a carboxylic acid halide to give IV' (IV') the resulting mixture IV or IV', which consists of two diastereomers, is resolved by fractional crystallization, the diastereomers are hydrolyzed to the alcohols Ia and Ib and, if desired, these are converted to the other compounds Ia and Ib in a conventional manner. Useful optically active chroman derivatives Ia and Ib and diastereomeric chromanyl esters IV and IV' are also claimed.

公开(公告)号：DE3301718A1

公开(公告)日：1984-07-26

申请号：DE3301718

申请日：1983-01-20

Applicant: BASF AG

Inventor： SCHAEFER ULRICH DR ,  JAEDICKE HAGEN DR ,  PAUST JOACHIM DR

IPC: C07C41/48 ,  C07C41/00 ,  C07C43/315 ,  C07C45/00 ,  C07C45/29 ,  C07C45/34 ,  C07C45/51 ,  C07C45/59 ,  C07C45/60 ,  C07C45/67 ,  C07C45/79 ,  C07C47/46 ,  C07C49/757 ,  C07C51/285 ,  C07C67/00 ,  C07D317/20 ,  C07D317/26 ,  C07D317/72 ,  C07D319/06 ,  C07D319/08 ,  C07F11/00

Abstract: 3-Hydroxy- alpha -cyclocitral derivatives of the general formula I in which R and R can be identical or different and denote in each case a linear or branched alkyl group having 1 to 6 C atoms, or else R and R together represent an ethyl group or a propylene group, each of which can be substituted by methyl groups or ethyl groups, and the preparation and use of these 3-hydroxy- alpha -cyclocitral derivatives for the preparation of safranal and 3-hydroxy- beta -cyclocitral.

公开(公告)号：CH599935A5

公开(公告)日：1978-06-15

申请号：CH991076

申请日：1976-08-03

Applicant: BASF AG

Inventor： JAEDICKE HAGEN DR ,  PAUST JOACHIM DR ,  SCHNEIDER JOACHIM DR

IPC: C07C403/24 ,  A23K1/16 ,  A23L5/41 ,  C07C20060101 ,  C07C49/76 ,  C07C67/00 ,  C07C401/00 ,  C07C403/00 ,  C07C175/00

Abstract: Echinenone is produced by oxidizing beta -carotene or retro-dehyro-carotene with iodic acid or a salt of iodic acid in the presence of a catalyst and of an inert diluent or solvent.

公开(公告)号：DE2456959A1

公开(公告)日：1976-06-16

申请号：DE2456959

申请日：1974-12-03

Applicant: BASF AG

Inventor： SCHOLZ HERBERT DR ,  KOENIG HORST DR ,  PAUST JOACHIM DR ,  WIERSDORFF WALTER-WIELANT DR ,  BLECHSCHMIDT WOLFGANG DR ,  KRETZSCHMAR ROLF DR ,  CHRISTOPHERS ENNO PROF DR

IPC: A61K8/67 ,  A61K31/16 ,  A61K31/20 ,  A61K31/23 ,  A61Q5/00 ,  A61Q19/00 ,  C07C403/00 ,  C07D295/185 ,  C07C175/00

公开(公告)号：DE2404306A1

公开(公告)日：1975-07-31

申请号：DE2404306

申请日：1974-01-30

Applicant: BASF AG

Inventor： HIMMELE WALTER DR ,  SIEGEL HARDO DR ,  PFOHL SIGBERG DR ,  PAUST JOACHIM DR ,  HOFFMANN WERNER DR ,  FRAUNBERG KARL VON DR

IPC: C07C31/137 ,  C07B61/00 ,  C07C27/00 ,  C07C29/14 ,  C07C29/141 ,  C07C41/00 ,  C07C43/303 ,  C07C45/00 ,  C07C45/50 ,  C07C47/347 ,  C07C47/45 ,  C07C51/00 ,  C07C61/13 ,  C07C67/00 ,  C07C69/753 ,  C07C209/00 ,  C07C209/26 ,  C07C209/28 ,  C07C209/52 ,  C07C209/88 ,  C07C211/03 ,  C07C211/17 ,  C07C211/19 ,  C07C211/27 ,  C07C211/38 ,  C07C211/44 ,  C07C213/08 ,  C07C231/00 ,  C07C231/02 ,  C07C233/55 ,  C07D295/02 ,  C07D295/03 ,  C07D295/22 ,  C07C47/34

Abstract: Pinanes substituted by a group X in the 3-position which group is formyl, or its alkyl-acetals or alkyl-hemiacetals, carboxylic acid, carboxylic acid chloride, carboxylic acid amide, hydroxymethyl or aminomethyl substituted in a specific manner at the nitrogen, the optical isomers of these compounds and a process for their manufacture by hydroformylation of alpha -pinene in the presence of rhodium catalysts, and conversion of the 3-formylpinane first produced into the above derivatives by conventional methods.

公开(公告)号：AT253030T

公开(公告)日：2003-11-15

申请号：AT00118466

申请日：2000-08-25

Applicant: BASF AG

Inventor： WEGNER CHRISTOPH DR ,  PAUST JOACHIM DR ,  ERNST HANSGEORG DR

IPC: C07C41/28 ,  C07B61/00 ,  C07C41/50 ,  C07C43/15

公开(公告)号：DE59503261D1

公开(公告)日：1998-09-24

申请号：DE59503261

申请日：1995-12-18

Applicant: BASF AG

Inventor： KRAUSE WOLFGANG DR ,  PAUST JOACHIM DR

IPC: B01J31/30 ,  C07C403/14 ,  C07D211/94

公开(公告)号：DE59308496D1

公开(公告)日：1998-06-10

申请号：DE59308496

申请日：1993-08-27

Applicant: BASF AG

Inventor： PAUST JOACHIM DR ,  ECKES PETER DR ,  SIEGEL WOLFGANG DR ,  BALKENHOHL FRIEDHELM DR ,  DOBLER WALTER DR ,  HUELLMANN MICHAEL DR

IPC: C07C323/52 ,  C07C67/00 ,  C07C69/06 ,  C07C69/708 ,  C07C319/08 ,  C07D339/04

公开(公告)号：DE59500893D1

公开(公告)日：1997-12-04

申请号：DE59500893

申请日：1995-06-30

Applicant: BASF AG

Inventor： DOBLER WALTER DR ,  KRAUSE WOLFGANG DR ,  PAUST JOACHIM DR ,  WOERZ OTTO DR ,  RHEUDE UDO DR ,  BURST WOLFRAM ,  DAEUWEL GUENTER ,  BERTRAM ARMIN ,  SCHULZ BERNHARD DR ,  WEGNER GUENTER DR ,  MUENSTER PETER DR ,  ERNST HANSGEORG DR ,  KOCHNER ARNO ,  ETZRODT HEINZ DR

IPC: C07C51/16 ,  C07C403/00 ,  C07C403/20

公开(公告)号：DE59306312D1

公开(公告)日：1997-06-05

申请号：DE59306312

申请日：1993-07-08

Applicant: BASF AG

Inventor： KRAUSE WOLFGANG DR ,  PAUST JOACHIM DR ,  DOBLER WALTER DR ,  JAEDICKE HAGEN DR

IPC: C07F9/54 ,  C07D319/06 ,  C07F9/655

Abstract: Improved process for preparing cyclic acetals of 3-formyl-2-butenyltriphenylphosphonium chloride by acetalisation of 3-formyl-2-butenyl acetate with an aliphatic 1,3-diol, conversion of the 4-acetoxyacetal obtained into the corresponding 4-hydroxyacetal, Vilmeier chlorination to give the corresponding 4-chloroacetal and subsequent reaction with triphenylphosphine, which is characterised in that the first 3 reaction steps are carried out in an aliphatic or cycloaliphatic hydrocarbon or hydrocarbon mixture having 6 to 8 C atoms and the reaction with triphenylphosphine is carried out in an alkanol having 1 to 3 C atoms and/or in an aliphatic or cycloaliphatic hydrocarbon having 6 to 8 C atoms or an appropriate hydrocarbon mixture. The process becomes particularly advantageous if the conversion of the 4-acetoxyacetal into the 4-hydroxyacetal is carried out with an aqueous alkali solution and in the presence of phase-transfer catalysts and the first three or all four reaction steps are carried out in the same C6-to C8-hydrocarbon.