公开(公告)号：EP0696587A3

公开(公告)日：1998-06-10

申请号：EP95112005

申请日：1995-07-31

Applicant: BASF AG

Inventor： HUELLMANN MICHAEL DR ,  BECKER RAINER DR ,  HASEL WINNFRIED DR ,  JESSEL BARBARA DR

IPC: C07D307/92

CPC classification number: C07D307/92

Abstract: Verfahren zur stereoselektiven Herstellung von (-)3a,6,6,9-Tetramethyl-perhydronaphtho[2,1-b]furan der Formel Ia

Abstract translation: 立体选择性制剂 的cpd。 （I），其被称为（ - ） - 3a,6,6,9-四甲基 - 全氢 - 萘并（2,1-b）呋喃，显示为3a，6,6,9a-四甲基衍生物。 的式（Ia）的化合物包括在液体中脱水和环化十氢-2-羟基-2,5,5,8-四甲基-1-萘 - 乙醇（II）。 相。 反应在10-50℃下，在10-100重量％的存在下，基于（II），具有高离子交换容量的商业蒙脱土催化剂或（b）在120-140℃下进行（a） 在10-100重量％的市售可用于制备柱色谱的活性酸性氧化铝的存在下。

公开(公告)号：DE4325848A1

公开(公告)日：1995-02-02

申请号：DE4325848

申请日：1993-07-31

Applicant: BASF AG

Inventor： HUELLMANN MICHAEL DR ,  BECKER RAINER DR ,  SCHARF EMIL DR

IPC: B01J23/74 ,  B01J23/88 ,  C07B61/00 ,  C07D295/08 ,  C07D295/088 ,  C07D295/023 ,  C07B37/10 ,  B01J23/70

Abstract: N-(2-Hydroxyethyl)piperazine of the formula I is prepared by reaction of triethanolamine of the formula II with ammonia in the presence of hydrogen at temperatures from 100 to 500 DEG C and pressures from 10 to 500 bar on heterogeneous catalysts, employing heterogeneous catalysts having an active mass containing 20 to 85% by weight of ZrO2 and/or Al2O3, 1 to 30% by weight of oxygen-containing compounds of copper, calculated as CuO, 1 to 60% by weight of oxygen-containing compounds of cobalt calculated as CoO and/or oxygen-containing compounds of nickel, calculated as NiO and/or oxygen-containing compounds of molybdenum, calculated as MoO3.

公开(公告)号：DE4039782A1

公开(公告)日：1992-06-17

申请号：DE4039782

申请日：1990-12-13

Applicant: BASF AG

Inventor： HUELLMANN MICHAEL DR ,  GNAD JOSEF DR ,  BECKER RAINER DR

IPC: C07C51/377 ,  C07C57/44 ,  C07C59/64 ,  C07C59/66 ,  C07C67/327 ,  C07C67/46 ,  C07C69/734

Abstract: 3-Arylacrylic acids and their derivatives I in which Ar represents an aryl radical which can additionally have substituents which do not react with ketene and which are stable to acids and bases under the conditions of the reaction described below, and R denotes hydrogen, alkali metal, alkaline earth metal, ammonium or a C1- to C20-alkyl group, are prepared by reacting, in a first reaction step, a dialkyl acetal of an aromatic aldehyde II in which R represents C1- to C4-alkyl, with ketene CH2=C=O in the presence of catalytic amounts of a protonic acid or a Lewis acid to give a 3-arylpropionic acid derivative III and reacting this intermediate III, in a second reaction step, in the presence of acid or base and, additionally in the case where R denotes a C1- to C20-alkyl group, with a C1- to C20-alkanol to give the end product I.

公开(公告)号：DE3928242A1

公开(公告)日：1991-02-28

申请号：DE3928242

申请日：1989-08-26

Applicant: BASF AG

Inventor： HUELLMANN MICHAEL DR ,  BECKER RAINER DR ,  JANITSCHKE LOTHAR DR ,  LAUTERBACH GERALD DR ,  BARTH WOLFGANG DR ,  JANSEN KLAAS

IPC: C07C29/14 ,  C07C33/05 ,  C07C33/12 ,  C07C33/14 ,  C07C45/68 ,  C07C47/225 ,  C07D309/04 ,  C07D309/30 ,  C07D309/32 ,  C07D311/96 ,  C07D493/10 ,  C11B9/00 ,  C11D3/50

Abstract: Cycloalkylidene derivatives of the general formulae Ia to Ic Ia Ib Ic where the dashed line is a possible additional chemical bond, the radicals R1 are identical or different C1-C4-alkenyl groups, R2 and R3 are each methyl or ethyl, R4 is hydrogen or one of the radicals R1, X is oxygen, methylene or a chemical bond, m is from 0 to 3 or, when X is methylene, is from 1 to 3, or, when X is methylene and R1 is methyl, is from 2 to 3 and n is from 0 to 3, are used as fragrance materials.

公开(公告)号：DE3918015A1

公开(公告)日：1990-12-06

申请号：DE3918015

申请日：1989-06-02

Applicant: BASF AG

Inventor： HUELLMANN MICHAEL DR ,  KUEKENHOEHNER THOMAS DR ,  BRENNER KARL ,  BECKER RAINER DR ,  SCHOMMER CHARLES DR ,  IRGANG MATTHIAS DR

IPC: B01J23/04 ,  B01J23/10 ,  B01J21/06 ,  B01J23/12 ,  C07B61/00 ,  C07C45/30 ,  C07C45/61 ,  C07C45/62 ,  C07C45/66 ,  C07C45/67 ,  C07C45/68 ,  C07C45/72 ,  C07C49/203 ,  C07C49/385

Abstract: The muscone of the formula I is prepared by bringing open-chain 2,15-diketones of the general formula II CH3-CO-X-CO-CH3 (II> in which X represents one of the radicals -(-CH2-)@(a> -CH=CH-(-CH2-)@CH=CH- (b> -CH2-CH=CH-(-CH2-)@CH=CH-CH2- (c> -CH2-CH2-CH=CH-(-CH2-)@CH=CH-CH2-CH2- (d) or -CH2-CH2-CH2-CH=CH-(-CH2-)@CH=CH-CH2-CH2-CH2- (e), into contact at temperatures of 300 to 400 DEG C in the presence of 5 to 15 % by weight of water, relative to the amount of catalyst, in the gas phase over a fixed-bed catalyst which contains TiO2, CeO2 or ThO2 as the catalytically active compound and hydrogenating catalytically the unsaturated cyclic ketone formed in this reaction by intramolecular aldol condensation. Furthermore, the open-chain unsaturated ketones of the formulae IIb, IIc and IId and advantageous processes for their preparation and their use as intermediates for a simple industrial muscone synthesis are claimed.

公开(公告)号：DE3815043A1

公开(公告)日：1989-11-16

申请号：DE3815043

申请日：1988-05-04

Applicant: BASF AG

Inventor： HUELLMANN MICHAEL DR ,  BECKER RAINER DR ,  LAUTERBACH GERALD DR ,  BUSCHMANN ERNST DR ,  ECKHARDT HEINZ DR ,  HIMMELE WALTER DR ,  BRUECKNER CHRISTIANE DR

IPC: C07C27/00 ,  C07C29/42 ,  C07C33/042 ,  C07C33/044 ,  C07C41/00 ,  C07C41/06 ,  C07C43/178 ,  C07C67/00 ,  C07C69/28 ,  C07C69/78 ,  C07D309/12 ,  C07F7/18

Abstract: The present invention relates to 3,9-dihydroxynonine and its derivatives which are protected in the 9-OH function, of the general formula I in which R represents hydrogen or an alcohol protective group which is customary per se, to processes for the preparation of the compounds I and to their use as intermediates for the synthesis of E-7,Z-9- dodecadienyl acetate, the pheromone of the grape berry moth.

公开(公告)号：DE59405291D1

公开(公告)日：1998-04-02

申请号：DE59405291

申请日：1994-07-16

Applicant: BASF AG

Inventor： BECKER RAINER DR ,  HUELLMANN MICHAEL DR ,  PALM CHRISTOF DR ,  FRANZISCHKA WOLFGANG DR

IPC: C08G65/06 ,  C08G65/02 ,  C08G65/10 ,  C08G65/20 ,  C08G65/26

Abstract: A process for the preparation of polytetrahydrofuran or C2- to C10-alkylene oxide-tetrahydrofuran copolymers having a mean molecular weight of from 250 to 20000 daltons by cationic polymerisation of tetrahydrofuran or tetrahydrofuran and C2- to C10-alkylene oxides in the presence of a promoter, in which process the catalyst used is a mixture of one or more C2- to C6-di- or tricarboxylic acids with boric acid.

公开(公告)号：DE59107467D1

公开(公告)日：1996-04-04

申请号：DE59107467

申请日：1991-11-29

Applicant: BASF AG

Inventor： HUELLMANN MICHAEL DR ,  GNAD JOSEF DR ,  BECKER RAINER DR

IPC: C07C51/377 ,  C07C57/44 ,  C07C59/64 ,  C07C59/66 ,  C07C67/327 ,  C07C67/46 ,  C07C69/734 ,  A61K7/40

Abstract: 3-Arylacrylic acids and their derivatives I in which Ar represents an aryl radical which can additionally have substituents which do not react with ketene and which are stable to acids and bases under the conditions of the reaction described below, and R denotes hydrogen, alkali metal, alkaline earth metal, ammonium or a C1- to C20-alkyl group, are prepared by reacting, in a first reaction step, a dialkyl acetal of an aromatic aldehyde II in which R represents C1- to C4-alkyl, with ketene CH2=C=O in the presence of catalytic amounts of a protonic acid or a Lewis acid to give a 3-arylpropionic acid derivative III and reacting this intermediate III, in a second reaction step, in the presence of acid or base and, additionally in the case where R denotes a C1- to C20-alkyl group, with a C1- to C20-alkanol to give the end product I.

公开(公告)号：DE59101533D1

公开(公告)日：1994-06-09

申请号：DE59101533

申请日：1991-03-08

Applicant: BASF AG

Inventor： HUELLMANN MICHAEL DR ,  MAYR HERBERT PROF DR ,  BECKER RAINER DR

IPC: B01J31/26 ,  C07B61/00 ,  C07C2/00 ,  C07C2/72 ,  C07C13/48

Abstract: A process for preparing 1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene of the formula I (I) comprises reacting p-cymene of the formula II (II) with a hexene of the formula IIIa, IIIb and/or IIIc (IIIa) (IIIb) (IIIc) in the presence of a catalytic amount of aluminum halide and a catalytic amount of a triphenylmethyl compound of the formula IV (IV) wherein R1, R2 and R3 are each, independently of one another, hydrogen, C1-C4-alkyl, nitro or halogen and X is hydrogen or halogen.

公开(公告)号：DE59001156D1

公开(公告)日：1993-05-13

申请号：DE59001156

申请日：1990-05-26

Applicant: BASF AG

Inventor： HUELLMANN MICHAEL DR ,  KUEKENHOEHNER THOMAS DR ,  BRENNER KARL ,  BECKER RAINER DR ,  IRGANG MATTHIAS DR ,  SCHOMMER CHARLES DR

IPC: B01J23/04 ,  B01J23/10 ,  B01J23/12 ,  B01J21/06 ,  C07B61/00 ,  C07C45/30 ,  C07C45/61 ,  C07C45/62 ,  C07C45/66 ,  C07C45/67 ,  C07C45/68 ,  C07C45/72 ,  C07C49/203 ,  C07C49/385

Abstract: The muscone of the formula I is prepared by bringing open-chain 2,15-diketones of the general formula II CH3-CO-X-CO-CH3 (II> in which X represents one of the radicals -(-CH2-)@(a> -CH=CH-(-CH2-)@CH=CH- (b> -CH2-CH=CH-(-CH2-)@CH=CH-CH2- (c> -CH2-CH2-CH=CH-(-CH2-)@CH=CH-CH2-CH2- (d) or -CH2-CH2-CH2-CH=CH-(-CH2-)@CH=CH-CH2-CH2-CH2- (e), into contact at temperatures of 300 to 400 DEG C in the presence of 5 to 15 % by weight of water, relative to the amount of catalyst, in the gas phase over a fixed-bed catalyst which contains TiO2, CeO2 or ThO2 as the catalytically active compound and hydrogenating catalytically the unsaturated cyclic ketone formed in this reaction by intramolecular aldol condensation. Furthermore, the open-chain unsaturated ketones of the formulae IIb, IIc and IId and advantageous processes for their preparation and their use as intermediates for a simple industrial muscone synthesis are claimed.