-
公开(公告)号：FR2852394A1
公开(公告)日：2004-09-17
申请号：FR0302972
申请日：2003-03-11
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： GENET MAGALIE , VIELLEROBE BERTRAND , BERIER FREDERIC , CLADE SOPHIE
IPC: A61B5/00 , G02B21/00 , G01N21/64 , G01N33/483
Abstract: The method consists in deflecting the excitation signal at a speed corresponding to acquisition of a number of images per second sufficient for real time use and in detecting the fluorescence signal at a detecting frequency corresponding to a minimum frequency for sampling the fibers one by one. The method uses an image guide consisting of several thousands of optical fibers, an excitation signal being emitted by a source, deflected and injected by turns into the optical fibers of the guide, each excitation point of the tissue in the fiber output emitting in return a fluorescence signal collected by the fiber, then detected and digitized to form an image element. The method also provides for the focussing of the beam in the fiber output to excite a subsurface plane to produce a confocal image. The method also provides for the production of a divergent beam in the fiber output capable of exciting a micro-volume of the tissue from the surface.
-
公开(公告)号：AU2003296826A1
公开(公告)日：2004-08-13
申请号：AU2003296826
申请日：2003-12-12
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： VIELLEROBE BERTRAND , BERIER FREDERIC , BONIFACE JEAN-MICHEL
Abstract: Light from a matrix of lasers (23) is focussed by an optical unit (24) on to an object (25). The lasers are vertical cavity surface emitting lasers (VCSEL) and each laser has a photo-detector (22) mounted at the rear and able to receive reflected light from the object. The photo-detector signals are amplified and digitized by a processing unit (21) and sent to a control unit (26) which controls the matrix and optical unit Independent claims are also included for the following: (1) An application of the system in which the miniature head is deployed at the head of an endoscope; (2) A method for realizing confocal parallel laser microscopy in which a photo-detector is attached to the rear of each laser to receive light returning from the object and the laser cavities are used as filters.
-
Patent Agency Ranking
公开(公告)号：FR2849215A1
公开(公告)日：2004-06-25
申请号：FR0216276
申请日：2002-12-20
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： VIELLEROBE BERTRAND , BERIER FREDERIC , BONIFACE JEAN MICHEL
Abstract: Light from a matrix of lasers (23) is focussed by an optical unit (24) on to an object (25). The lasers are vertical cavity surface emitting lasers (VCSEL) and each laser has a photo-detector (22) mounted at the rear and able to receive reflected light from the object. The photo-detector signals are amplified and digitized by a processing unit (21) and sent to a control unit (26) which controls the matrix and optical unit Independent claims are also included for the following: (1) An application of the system in which the miniature head is deployed at the head of an endoscope; (2) A method for realizing confocal parallel laser microscopy in which a photo-detector is attached to the rear of each laser to receive light returning from the object and the laser cavities are used as filters.
-
54.发明专利
公开(公告)号：AU2003269019A1
公开(公告)日：2004-02-09
申请号：AU2003269019
申请日：2003-07-11
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： PERCHANT AYMERIC , GOUALHER GEORGES LE , BERIER FREDERIC
Abstract: A method for processing an image acquired through a guide consisting of a plurality of optical fibers includes, for each optical fiber, isolating on the acquired image a zone corresponding to the optical fiber, locally processing each zone individually to correct the photon flux detected in each optical fiber, then reconstructing the acquired image by eliminating the pattern caused by the optical fiber. The method also includes a sampling process for obtaining, for each optical fiber and from a sampling image, a sample injection rate which can be used for reconstructing the acquired images. The method also includes a prior step which consists in detecting the fibers from a target.
-
公开(公告)号：CA2491748A1
公开(公告)日：2004-01-29
申请号：CA2491748
申请日：2003-07-11
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： CLADE SOPHIE , VIELLEROBE BERTRAND , BERIER FREDERIC , GENET MAGALIE
IPC: G01N21/64 , A61B1/00 , A61B1/04 , A61B5/00 , G02B21/00 , G02B23/24 , G02B23/26 , G02B26/10 , H04N1/028
Abstract: Le procédé utilise un guide d'image fait de plusieurs milliers de fibres optiques, un signal d'excitation étant émis par une source, dévié et injecté tout à tour dans l'une des fibres dudit guide, chaque point d'excitation du tissu en sortie de fibre émettant en retour un signal de fluorescence collec té par ladite fibre, puis détecté et numérisé pour former un élément d'image. Selon un premier aspect, le procédé prévoit la focalisation du faisceau en sortie de fibre pour exciter un plant subsurfacique et réaliser une image confocale. Selon un second aspect le procédé prévoit de produire un faisceau divergent en sortie de fibre susceptible d'exciter un microvolume du tissu depuis la surface. Selon l'invention, le procédé est caractérisé en ce que l'on dévie le signal d'excitation à une vitesse correspondant à l'acquisitio n d'un nombre d'images par seconde suffisant pour une utilisation en temps rée l et en ce que l'on détecte le signal de fluorescence à une fréquence de détection correspondant à une fréquence minimale d'échantillonnage des fibre s une à une. Grâce à l'invention, on peut réaliser une image in vivo in situ e t en temps réel.
-
公开(公告)号：AU2002364671A1
公开(公告)日：2003-07-15
申请号：AU2002364671
申请日：2002-12-20
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： VIELLEROBE BERTRAND , GENET MAGALIE , BERIER FREDERIC , LACOMBE FRANCOIS , PERCHANT AYMERIC , GOUALHER GEORGES LE , MARTI SANDRA , BOURRIAUX STEPHANE
Abstract: Equipment includes an image guide ( 1 ) consisting of flexible optical fibers with: on the proximal end side: a source ( 2 ), angular scanning elements ( 3 ), injection elements ( 4 ) in one of the fibers, elements for splitting ( 5 ) the illuminating beam and the backscattered signal, elements for spatial filtering ( 6 ), elements for detecting ( 7 ) the signal, electronic elements ( 8 ) for controlling, analyzing and digital processing of the detected signal and display; and on the distal end side: an optical head ( 9 ) for focusing the illuminating beam exiting from the illuminated fiber. The scanning elements include a resonant line mirror (M 1 ) and a galvanometric field mirror (M 2 ) with a variable frequency and two afocal optical systems adapted to conjugate the two mirrors (M 1 , M 2 ) firstly in the field mirror (M 2 ) and the injection elements ( 4 ) in the image guide in a second step.
-
公开(公告)号：CA2471724A1
公开(公告)日：2003-07-10
申请号：CA2471724
申请日：2002-12-20
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： GENET MAGALIE , ABRAT BENJAMIN , BOURRIAUX STEPHANE , BERIER FREDERIC , VIELLEROBE BERTRAND , LOISEAU ALEXANDRE
Abstract: Elle est prévue pour équiper l'extrémité distale d'un faisceau de fibres optiques souples (2), destinée à venir au contact d'une surface d'analyse et comprenant des moyens optiques (3) pour focaliser un signal d'excitation en un point focal dit d'excitation situé à une profondeur donnée sous la surface d'analyse et pour prélever un signal rétroémis par le point focal d'excitation qui est véhiculé en retour par ledit faisceau de fibres. Elle est caractérisée par un tube porte-optique (4) au sein duquel sont introduits d'un côté la partie terminale distale (1) du faisceau de fibres (2) et de l'autre les moyens optiques, ces derniers comprenant une lame (21) placée au contact de l'extrémité (14) du faisceau de fibres dont l'indice est proche de celui du coeur des fibres et un bloc optique de focalisation (3), un hublot de sortie (30) étant en outre prévu adapté à réaliser une adaptation d'indice de manière à s'affranchir de la réflexion parasite s'opérant sur la surface d'analyse.
-
-
-
-
-
-
Search Results
57
records
(took 0.021 seconds)
