公开(公告)号：AU2016216569B2

公开(公告)日：2018-01-25

申请号：AU2016216569

申请日：2016-08-16

Applicant: VERTEX PHARMA

Inventor： ROWE WILLIAM ,  HURTER PATRICIA ,  YOUNG CHRISTOPHER ,  DINEHART KIRK ,  OVERHOFF KIRK ,  GROOTENHUIS PETER D J ,  BOTFIELD MARTYN ,  GROSSI ALFREDO ,  VERWIJS MARINUS JACOBUS

IPC: A61K47/32

Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3 carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.

公开(公告)号：ZA201101097B

公开(公告)日：2012-05-30

申请号：ZA201101097

申请日：2011-02-10

Applicant: VERTEX PHARMA

Inventor： ROWE WILLIAM ,  HURTER PATRICIA ,  YOUNG CHRISTOPHER ,  DINEHART KIRK ,  VERWIJS MARINUS JACOBUS ,  OVERHOFF KIRK ,  GROOTENHUIS PETER D J ,  BOTFIELD MARTYN C ,  GROSSI ALFREDO

IPC: A61K20060101

Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.

公开(公告)号：MX2012001939A

公开(公告)日：2012-03-29

申请号：MX2012001939

申请日：2010-02-18

Applicant: VERTEX PHARMA

Inventor： GROOTENHUIS PETER D J ,  ZLOKARNIK GREGOR ,  HURTER PATRICIA ,  GROSSI ALFREDO ,  ROWE WILLIAM ,  DINEHART KIRK ,  OVERHOFF KIRK ,  BOTFIELD MARTYN ,  VERWIJS MARINUS JACOBUS ,  GOOR FREDRICK F VAN ,  YOUNG CHRISTOPHER R

IPC: A61K47/32 ,  A61K9/14 ,  A61K31/47 ,  A61P19/00 ,  A61P19/10 ,  A61P43/00

Abstract: La presente invención se relaciona con composiciones farmacéuticas que comprenden una dispersión sólida de N-[2,4-Bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-dihidro-4-oxoquin olina-3-carboxamida, los métodos para elaborar las composiciones farmacéuticas de la presente invención, y los métodos para administrar las composiciones farmacéuticas de la presente invención.

公开(公告)号：AU2009282419A1

公开(公告)日：2010-02-18

申请号：AU2009282419

申请日：2009-08-13

Applicant: VERTEX PHARMA

Inventor： ROWE WILLIAM ,  HURTER PATRICIA ,  YOUNG CHRISTOPHER ,  DINEHART KIRK ,  VERWIJS MARINUS JACOBUS ,  OVERHOFF KIRK ,  GROOTENHUIS PETER D J ,  BOTFIELD MARTYN ,  GROSSI ALFREDO

IPC: A61K47/32

Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.