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1.发明申请FORMULATIONS OF 3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL) CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID 审中-公开3-（6-（1-（2,2-二氟苯并[D] [1,3]二氧杂环戊烯-5-基）环丙基）羰基氧基）-3-甲基吡啶-2-基）苯甲酸的制备
公开(公告)号：WO2009076141A8
公开(公告)日：2010-07-15
申请号：PCT/US2008085457
申请日：2008-12-04
Applicant: VERTEX PHARMA , KESHAVARZ-SHOKRI ALI , YOUNG CHRISTOPHER
Inventor： KESHAVARZ-SHOKRI ALI , YOUNG CHRISTOPHER
CPC classification number: A61K9/10 , A61K9/0095 , A61K31/443
Abstract: The present invention relates to formulations of 3-(6-(l-(2,2- difluorobenzo[d] [ 1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid, pharmaceutical packs or kits thereof, and methods of treatment therewith.
Abstract translation: 本发明涉及3-（6-（1-（2,2-二氟苯并[d] [1,3]二氧杂环戊烯-5-基）环丙烷甲酰氨基）-3-甲基吡啶-2-基）苯甲酸，药物 包装或试剂盒，以及其处理方法。
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2.发明申请DOSAGE UNITS OF 3-(6-(1-(2,2-DIFLUOROBENZO [D] [1,3] DIOXOL-5-YL) CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID 审中-公开3-（6-（1-（2,2-二氟代苯并[D] [1,3]二氧杂环戊烯-5-基）环丙基氨基甲酰基）-3-甲基吡啶-2-基）苯甲酸的剂量单位
公开(公告)号：WO2010037066A3
公开(公告)日：2010-05-14
申请号：PCT/US2009058677
申请日：2009-09-29
Applicant: VERTEX PHARMA , YOUNG CHRISTOPHER
Inventor： YOUNG CHRISTOPHER
IPC: A61K9/48 , A61K31/443
CPC classification number: A61K31/47 , A61K9/2018 , A61K9/2054 , A61K9/2059 , A61K9/4858 , A61K9/4866 , A61K31/443 , A61K45/06 , C07D405/12 , A61K2300/00
Abstract: The present invention relates to formulations of 3 -(6-(I -(2,2- difluorobenzo[d][l,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2- yl)benzoic acid in Form I, pharmaceutical packs or kits thereof, and methods of treatment therewith.
Abstract translation: 本发明涉及3-（6-（1-（2,2-二氟苯并[d] [1,3]间二氧杂环戊烯-5-基）环丙烷甲酰氨基）-3-甲基吡啶-2-基）苯甲酸的形式， I，其药物包装或药盒，以及用其治疗的方法。
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3.发明申请PHARMACEUTICAL COMPOSITION OF N- [2,4-BIS (1, 1 -DIMETHYLETHYL) - 5 - HYDROXYPHENYL] - 1, 4 - DIHYDRO - 4 - OXOQUINOLINE - 3 - CARBOXAMIDE AND ADMINISTRATION THEREOF 审中-公开N- [2,4-BIS（1,1-二甲基）-5-羟基苯基] -1,4-二氢-4-氧杂喹啉-3-羧酰胺的药物组合物及其施用方法
公开(公告)号：WO2010019239A3
公开(公告)日：2011-05-26
申请号：PCT/US2009004629
申请日：2009-08-13
Applicant: VERTEX PHARMA , ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO
IPC: A61K47/32
CPC classification number: A61K9/1652 , A61K9/1635 , A61K9/2054 , A61K9/282 , A61K31/47
Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline- 3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
Abstract translation: 本发明涉及包含N- [2,4-双（1,1-二甲基乙基）-5-羟基苯基] -1,4-二氢-4-氧代喹啉-3-甲酰胺的固体分散体的药物组合物，制造方法 本发明的药物组合物和本发明的药物组合物的给药方法。
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4.发明申请FORMULATIONS OF 3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL) CYCKLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID 审中-公开3-（6-（1-（2,2-二氟苯并[D] [1,3]二氧戊环-5-基）环丙基碳酰氨基）-3-甲基吡啶-2-基）苯甲酸的制剂
公开(公告)号：WO2009076141A3
公开(公告)日：2009-11-12
申请号：PCT/US2008085457
申请日：2008-12-04
Applicant: VERTEX PHARMA , KESHAVARZ-SHOKRI ALI , YOUNG CHRISTOPHER
Inventor： KESHAVARZ-SHOKRI ALI , YOUNG CHRISTOPHER
CPC classification number: A61K9/10 , A61K9/0095 , A61K31/443
Abstract: The present invention relates to formulations of 3-(6-(l-(2,2- difluorobenzo[d] [ 1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid, pharmaceutical packs or kits thereof, and methods of treatment therewith.
Abstract translation: 本发明涉及3-（6-（1-（2,2-二氟苯并[d] [1,3]间二氧杂环戊烯-5-基）环丙烷甲酰氨基）-3-甲基吡啶-2-基）苯甲酸的制剂，药物 包装或药盒，以及用其治疗的方法。
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公开(公告)号：HUE056525T2
公开(公告)日：2022-02-28
申请号：HUE16185289
申请日：2011-04-07
Applicant: VERTEX PHARMA
Inventor： VERWIJS MARINUS , ALARGOVA ROSSITZA , KAUSHIK RITU , KADIYALA IRINA , YOUNG CHRISTOPHER
IPC: A61K9/16 , A61K9/20 , A61K9/28 , C07D213/75 , C07D405/12 , C07D405/14
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Patent Agency Ranking
公开(公告)号：PL3345625T3
公开(公告)日：2021-06-14
申请号：PL17204189
申请日：2009-08-13
Applicant: VERTEX PHARMA
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公开(公告)号：RS61408B1
公开(公告)日：2021-03-31
申请号：RSP20210129
申请日：2009-08-13
Applicant: VERTEX PHARMA
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公开(公告)号：SI2328618T1
公开(公告)日：2018-04-30
申请号：SI200931803
申请日：2009-08-13
Applicant: VERTEX PHARMA
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公开(公告)号：DK2328618T3
公开(公告)日：2018-02-19
申请号：DK09789125
申请日：2009-08-13
Applicant: VERTEX PHARMA
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公开(公告)号：AU2016216569A1
公开(公告)日：2016-09-01
申请号：AU2016216569
申请日：2016-08-16
Applicant: VERTEX PHARMA
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO , VERWIJS MARINUS JACOBUS
IPC: A61K47/32
Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3 carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
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