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    나프토［1,2-ｂ］퓨란-2-카르복사미드 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 ＭＣＨ 수용체-1 관련 질환의 예방 또는 치료용 약학적 조성물
    63.
    发明公开
    나프토［1,2-ｂ］퓨란-2-카르복사미드 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 ＭＣＨ 수용체-1 관련 질환의 예방 또는 치료용 약학적 조성물 有权
    萘普生[1,2-B]呋喃-2-羧酰胺衍生物或其药学上可接受的盐，其制备方法和药物组合物，用于预防或治疗含有作为活性成分的MCH受体-1相关疾病

    公开(公告)号：KR1020130042846A

    公开(公告)日：2013-04-29

    申请号：KR1020110106961

    申请日：2011-10-19

    Applicant: 한국화학연구원

    Inventor： 이규양 ,  임채조 ,  김낙정 ,  김지영 ,  이가은

    IPC: C07D405/12 ,  A61K31/4525 ,  A61P3/00 ,  A61P25/00

    Abstract: PURPOSE: A pharmaceutical composition containing a naphtho[1,2-b]furan-2-carboxamide derivative or a pharmaceutically acceptable salt thereof for preventing or treating MCH receptor 1-related diseases is provided to prevent or treat metabolic disorders, anxiety, and depression. CONSTITUTION: A naphtho[1,2-b]furan-2-carboxamide derivative or a pharmaceutically acceptable salt thereof contains a compound of chemical formula 1. A health functional food composition for preventing or treating MCH-related diseases contains the derivative of chemical formula 1 and a pharmaceutically acceptable salt thereof as active ingredients. The MHC-related diseases are selected from the group consisting of obesity, diabetes, metabolic disorders, anxiety, and depression. The derivative of a predetermined structure is used as a preventive and therapeutic agent for MCH-related diseases.

    Abstract translation: 目的：提供含有萘并[1,2-b]呋喃-2-甲酰胺衍生物或其药学上可接受的盐用于预防或治疗MCH受体1相关疾病的药物组合物，以预防或治疗代谢紊乱，焦虑和抑郁 。 构成：萘并[1,2-b]呋喃-2-甲酰胺衍生物或其药学上可接受的盐含有化学式1的化合物。用于预防或治疗MCH相关疾病的健康功能食品组合物含有化学式 1及其药学上可接受的盐作为活性成分。 MHC相关疾病选自肥胖症，糖尿病，代谢紊乱，焦虑和抑郁。 预定结构的衍生物用作MCH相关疾病的预防和治疗剂。

    피리다지논 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 포함하는 약학적 조성물
    67.
    发明公开
    피리다지논 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 포함하는 약학적 조성물 有权
    吡咯烷酮衍生物或其药学上可接受的盐，其制备方法和包含其的药物组合物

    公开(公告)号：KR1020120109877A

    公开(公告)日：2012-10-09

    申请号：KR1020110027656

    申请日：2011-03-28

    Applicant: 한국화학연구원

    Inventor： 김낙정 ,  강남숙 ,  김성환 ,  유성은 ,  이규양 ,  서지희 ,  임채조 ,  황순희

    IPC: C07D237/14 ,  C07D401/04 ,  A61K31/50 ,  A61P5/26

    Abstract: PURPOSE: A pharmaceutical composition containing pyridazinone derivatives is provided to effectively suppress cancer cell growth and to prevent or treat benign prostatic hyperplasia, acne, sterility, or male pattern baldness. CONSTITUTION: A pyridazinone derivative is denoted by chemical formula 1. A pharmaceutical composition for preventing or treating androgen-associated diseases contains the derivatives of chemical formula 1 or pharmaceutically acceptable salt thereof as an active ingredient. The pharmaceutical composition is administered in the form of a tablet, pill, soft/hard capsule, liquid, suspension, emulsion, syrup, granule, elixir, or troche by oral administration and hypodermic injection, intravenous injection, intramuscular injection by parenteral administration.

    Abstract translation: 目的：提供含有哒嗪酮衍生物的药物组合物，以有效抑制癌细胞生长并预防或治疗良性前列腺增生，痤疮，不育或男性型秃发。 构成：哒嗪酮衍生物由化学式1表示。用于预防或治疗雄激素相关疾病的药物组合物含有化学式1的衍生物或其药学上可接受的盐作为活性成分。 药物组合物通过口服给药和皮下注射，静脉内注射，通过肠胃外给药肌内注射，以片剂，丸剂，软/硬胶囊，液体，悬浮液，乳剂，糖浆，颗粒剂，酏剂或锭剂的形式给药。

    1-［4-（4-니트로-페녹시）-페닐］-프로판-1-온을 유효성분으로 함유하는 톡소포자충 및 콕시디움에 기인한 질환의 예방 및 치료용 조성물
    69.
    发明公开
    1-［4-（4-니트로-페녹시）-페닐］-프로판-1-온을 유효성분으로 함유하는 톡소포자충 및 콕시디움에 기인한 질환의 예방 및 치료용 조성물 有权
    包含1- [4-（4-硝基 - 苯氧基） - 苯基] - 丙-1-酮的组合物，用于预防和治疗由毒素和COCCIDI造成的疾病

    公开(公告)号：KR1020110121142A

    公开(公告)日：2011-11-07

    申请号：KR1020100040599

    申请日：2010-04-30

    Applicant: 원광대학교산학협력단 ,  한국화학연구원

    Inventor： 박현 ,  김성연 ,  김석 ,  이규양 ,  김춘매 ,  서지희 ,  김낙정

    IPC: A61K31/125 ,  A61P31/00 ,  A61P33/00 ,  A61P43/00

    Abstract: PURPOSE: A composition containing 1-[4-(4-nitro-phenoxy)-phenyl]-propane-1-one(1434NJ0221) is provided to prevent and treat diseases caused by coccidium. CONSTITUTION: A pharmaceutical composition for preventing and treating diseases caused by Eimeria tenella and coccidium contains 0.1-50 wt% of 1-[4-(4-nitro-phenoxy)-phenyl]-propane-1-one as an active ingredient. A veterinary composition for preventing and treating diseases caused by Eimeria tenella and coccidium contains 1-[4-(4-nitro-phenoxy)-phenyl]-propane-1-one of structural formula A as an active ingredient. An animal infected by Eimeria tenella and coccidium is mammals, fishes, or poultry.

    Abstract translation: 目的：提供含有1- [4-（4-硝基 - 苯氧基） - 苯基] - 丙烷-1-酮（1434NN0221）的组合物，用于预防和治疗由球虫引起的疾病。 构成：用于预防和治疗由艾美球虫和球虫引起的疾病的药物组合物含有0.1-50重量％的1- [4-（4-硝基 - 苯氧基） - 苯基] - 丙烷-1-酮作为活性成分。 用于预防和治疗由艾美球虫和球虫引起的疾病的兽用组合物含有作为活性成分的结构式A的1- [4-（4-硝基 - 苯氧基） - 苯基] - 丙烷-1-酮。 被艾美球虫感染的动物是哺乳动物，鱼类或家禽。

    인덴온 유도체 및 이를 포함하는 약학적 조성물
    70.
    发明公开
    인덴온 유도체 및 이를 포함하는 약학적 조성물 有权
    茚酮衍生物和包含其的药物组合物

    公开(公告)号：KR1020110028050A

    公开(公告)日：2011-03-17

    申请号：KR1020090085954

    申请日：2009-09-11

    Applicant: 한국화학연구원

    Inventor： 허정녕 ,  배명애 ,  김낙정 ,  장성연 ,  강남숙 ,  유성은 ,  황은숙

    IPC: C07D265/33 ,  C07D265/32 ,  A61K31/4965 ,  A61P19/10

    CPC classification number: C07D213/50 ,  C07D213/89 ,  C07D239/26 ,  C07D241/12 ,  C07D295/088 ,  C07D333/22

    Abstract: PURPOSE: A pharmaceutical composition containing indenone derivative for preventing or treating bone diseases is provided to suppress bone absorption of osteoclast. CONSTITUTION: An indenone derivative is denoted by chemical formula 1. In chemical formula 1, R1 is 5-10 cyclic heteroaryl of C6-C10 aryl, Y is CH, N, N+(-C1-C6alkyl) or N+(-O-). A pharmaceutical composition for preventing and treating bone diseases contains the indenone derivative and physiologically acceptable salt as an active ingredient. The bone diseases is osteoporosis, fracture, periodontal diseases, bone metastatic cancer, or rheumatoid arthritis.

    Abstract translation: 目的：提供含有用于预防或治疗骨病的茚酮酮衍生物的药物组合物，以抑制破骨细胞的骨吸收。 在化学式1中，R1是C6-C10芳基的5-10个环状杂芳基，Y是CH，N，N +（ - C1-C6烷基）或N +（ - O-） 。 用于预防和治疗骨疾病的药物组合物含有茚酮酮衍生物和生理学上可接受的盐作为活性成分。 骨病是骨质疏松症，骨折，牙周病，骨转移性癌症或类风湿性关节炎。

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