公开(公告)号：NO20025759L

公开(公告)日：2003-01-14

申请号：NO20025759

申请日：2002-11-29

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JOERG ,  HERR DIETER ,  LAUX VOLKER ,  HEGER ROBERT

IPC: A61K47/12 ,  A61K9/16 ,  A61K31/726 ,  A61K31/727 ,  A61K47/14 ,  A61K47/30 ,  A61K47/32 ,  A61K47/34 ,  A61K47/38 ,  A61K47/44 ,  A61P1/04 ,  A61P7/02 ,  A61P9/00 ,  A61P9/06 ,  A61P9/10 ,  A61P11/00 ,  A61P13/12 ,  A61P19/02 ,  A61P27/02 ,  A61P29/00 ,  A61P35/00 ,  A61P35/04 ,  A61P37/06

公开(公告)号：NO20025759D0

公开(公告)日：2002-11-29

申请号：NO20025759

申请日：2002-11-29

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JOERG ,  HERR DIETER ,  LAUX VOLKER ,  HEGER ROBERT

IPC: A61K47/12 ,  A61K9/16 ,  A61K31/726 ,  A61K31/727 ,  A61K47/14 ,  A61K47/30 ,  A61K47/32 ,  A61K47/34 ,  A61K47/38 ,  A61K47/44 ,  A61P1/04 ,  A61P7/02 ,  A61P9/00 ,  A61P9/06 ,  A61P9/10 ,  A61P11/00 ,  A61P13/12 ,  A61P19/02 ,  A61P27/02 ,  A61P29/00 ,  A61P35/00 ,  A61P35/04 ,  A61P37/06 ,  A61K

公开(公告)号：CA2408915A1

公开(公告)日：2002-11-13

申请号：CA2408915

申请日：2001-05-29

Applicant: BASF AG

Inventor： BERNDL GUNTHER ,  HEGER ROBERT ,  WILKE PETER ,  STADLER MICHAEL ,  BREITENBACH JORG ,  ROSENBERG JORG

IPC: A61F13/53 ,  A23P1/02 ,  A23P1/08 ,  A61F13/49 ,  A61K9/107 ,  A61K9/16 ,  A61K47/00 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/26 ,  A61K47/32 ,  A61K47/34 ,  A61K47/38

Abstract: The present invention relates to self-emulsifying formulations based on an active ingredient component and a formulation base with a lipid component and with a binder component and to the use of this formulation as dosage form in the life science sector. The invention also describes a process for producing self-emulsifying formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as dosage form advantageously by use of melt extrusion. The formulations spontaneously form emulsions in water or aqueous media.

公开(公告)号：AU7982001A

公开(公告)日：2002-02-25

申请号：AU7982001

申请日：2001-08-16

Applicant: BASF AG

Inventor： HEGER ROBERT ,  SCHROF WOLFGANG ,  SEUFERT MICHAEL ,  NORD SIMON ,  KOHLE HARALD

IPC: G01N33/15 ,  A61K9/10 ,  A61K9/107 ,  B01J4/00 ,  B01J19/00 ,  C07B61/00 ,  G01N13/00 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/08 ,  G01N35/10 ,  G01N37/00

公开(公告)号：DE10026699A1

公开(公告)日：2001-12-06

申请号：DE10026699

申请日：2000-05-30

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JOERG ,  HERR DIETER ,  LAUX VOLKER ,  HEGER ROBERT

IPC: A61K47/12 ,  A61K9/16 ,  A61K31/726 ,  A61K31/727 ,  A61K47/14 ,  A61K47/30 ,  A61K47/32 ,  A61K47/34 ,  A61K47/38 ,  A61K47/44 ,  A61P1/04 ,  A61P7/02 ,  A61P9/00 ,  A61P9/06 ,  A61P9/10 ,  A61P11/00 ,  A61P13/12 ,  A61P19/02 ,  A61P27/02 ,  A61P29/00 ,  A61P35/00 ,  A61P35/04 ,  A61P37/06

Abstract: The invention relates to formulations based on at least one heparin, one glycosaminoglycan or on one heparinoid, and to a formulation base with a lipid constituent and a polymer constituent. The invention also relates to the use of this formulation as a medicament for orally administering at least one heparin, one glycosaminoglycan or one heparinoid, and to a method for preparing the formulations by mixing the formulation constituents while forming a plastic mixture and, optionally, while preparing the formulations as a medicament while, advantageously, using melt extrusion. The lipid constituent advantageously comprises active substance-promoting properties, whereas the polymer constituent is soluble or is capable of swelling. The invention provides that at least portions of the lipid constituent are embedded in a polymer matrix, preferably in molecularly dispersed form. The formulations can form emulsions in water or in aqueous fluids.

公开(公告)号：DE19951617A1

公开(公告)日：2001-05-03

申请号：DE19951617

申请日：1999-10-26

Applicant: BASF AG

Inventor： HEGER ROBERT ,  BREITENBACH JOERG ,  BERNDL GUNTHER ,  BINDER RUDOLF

IPC: A61K9/14 ,  A61K9/50 ,  A61K9/51 ,  A61K38/00 ,  A61K9/20 ,  A61K9/48 ,  A61K38/13

Abstract: The invention relates to solid pharmaceutical galenic forms comprising an agent in the form of a physical mixture of two different preparations with regard to the physical state of the agent.

公开(公告)号：CA2388614A1

公开(公告)日：2001-05-03

申请号：CA2388614

申请日：2000-10-17

Applicant: BASF AG

Inventor： BINDER RUDOLF ,  BERNDL GUNTHER ,  BREITENBACH JORG ,  HEGER ROBERT

IPC: A61K9/14 ,  A61K9/50 ,  A61K9/51 ,  A61K38/00 ,  A61K38/13 ,  A61K9/20

Abstract: The invention relates to solid pharmaceutical galenic forms comprising an agent in the form of a physical mixture of two different preparations with regard to the physical state of the agent.

公开(公告)号：DE19856432A1

公开(公告)日：2000-06-15

申请号：DE19856432

申请日：1998-12-08

Applicant: BASF AG

Inventor： HEGER ROBERT ,  AUWETER HELMUT ,  BREITENBACH JOERG ,  BOHN HERIBERT

IPC: A61K47/30 ,  A61K8/02 ,  A61K8/04 ,  A61K8/11 ,  A61K8/72 ,  A61K9/00 ,  A61K9/06 ,  A61K9/10 ,  A61K9/20 ,  A61K9/51 ,  A61K9/70 ,  A61K31/426 ,  A61K47/42 ,  A61Q19/00

Abstract: Nanoparticulate preparations of pharmaceutical and cosmetic active substances with a core-shell structure, whereby the active substance is present in an X-ray amorphous form, together with a polymer matrix and the shell consists of a stabilizing sheathing matrix.