公开(公告)号：HUT55954A

公开(公告)日：1991-07-29

申请号：HU849390

申请日：1990-12-28

Applicant: BASF AG

Inventor： ZIPPERER BERNHARD ,  AMMERMANN EBERHARD ,  LORENZ GISELA ,  ZIERKE THOMAS ,  SAUTER HUBERT

IPC: A01N43/40 ,  C07D213/30 ,  C07D213/50 ,  C07D405/04 ,  C07D405/14 ,  C07D409/06 ,  C07D409/14 ,  C07D413/06 ,  C07D413/14

Abstract: 3-Substituted pyridines I … …… … (X = OH; Y = -O-CHO, -O-CO-W R , -O-SO2-W R or X + Y = -O-CH(W R )-O-, O CH(O W R )-O-, -O-C-(W R )(O-W R )-O-; W -W = direct bond, -CH2-, -CH2-CH2, -CH(CH3)-, -CH2O-, -CH2S-; R -R = optionally cycloalkyl-substituted C1-C6-alkyl, C1-C6-haloalkyl, C3-C8-cycloalkyl which is optionally substituted by 1-3 alkyl radicals, or C1-C4-alkoxy-C1-C4-alkyl, C1-C4-alkylthio-C1-C4-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, optionally substituted phenyl or naphthyl, optionally substituted 5-/6-membered heteroaryl having 1 to 3 hetero atoms; … R is additionally H when X + Y = -O-CH(W R )-O-, -O-CH(O-W R )-O- or -O-C(W R )(O-W R )-O- and W2 = direct bond), … with the exception of cis-1-(2,4-dichlorophenyl)-2-(pyrid-3-yl)- 1,2-epoxypropane, trans-1-(2,4-dichlorophenyl)-2-(pyrid-3-yl)- 1,2-epoxypropane, 1-(2,4-dichlorophenyl)-2-(pyrid-3-yl)- 1,2-epoxybutane and 2,4-dichloro- alpha -[1-hydroxy-1-(pyrid-3-yl)ethyl]- benzyl methanesulphonate … and the N-oxides and phytophysiologically acceptable salts with mineral acids, and metal complexes of I. … The compounds I are suitable as fungicides.

公开(公告)号：AU612752B2

公开(公告)日：1991-07-18

申请号：AU2762588

申请日：1988-12-30

Applicant: BASF AG

Inventor： ZIPPERER BERNHARD ,  BUSCHMANN ERNST ,  LAUER MANFRED ,  AMMERMANN EBERHARD ,  LORENZ GISELA

IPC: A01N43/40 ,  C07D213/89

Abstract: Substituted pyridine-N-oxides of the formula (I) where R1 is alkyl and R2 is phenyl or substituted phenyl, salts thereof which are physiologically tolerated by plants, and fungicides containing them.

公开(公告)号：AU6854990A

公开(公告)日：1991-07-11

申请号：AU6854990

申请日：1990-12-28

Applicant: BASF AG

Inventor： ZIERKE THOMAS ,  ZIPPERER BERNHARD ,  SAUTER HUBERT ,  AMMERMANN EBERHARD ,  LORENZ GISELA

IPC: A01N43/40 ,  C07D213/30 ,  C07D213/50 ,  C07D405/04 ,  C07D409/06 ,  C07D413/06 ,  C07D413/14 ,  C07D409/14

Abstract: 3-Substituted pyridines I … …… … (X = OH; Y = -O-CHO, -O-CO-W R , -O-SO2-W R or X + Y = -O-CH(W R )-O-, O CH(O W R )-O-, -O-C-(W R )(O-W R )-O-; W -W = direct bond, -CH2-, -CH2-CH2, -CH(CH3)-, -CH2O-, -CH2S-; R -R = optionally cycloalkyl-substituted C1-C6-alkyl, C1-C6-haloalkyl, C3-C8-cycloalkyl which is optionally substituted by 1-3 alkyl radicals, or C1-C4-alkoxy-C1-C4-alkyl, C1-C4-alkylthio-C1-C4-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, optionally substituted phenyl or naphthyl, optionally substituted 5-/6-membered heteroaryl having 1 to 3 hetero atoms; … R is additionally H when X + Y = -O-CH(W R )-O-, -O-CH(O-W R )-O- or -O-C(W R )(O-W R )-O- and W2 = direct bond), … with the exception of cis-1-(2,4-dichlorophenyl)-2-(pyrid-3-yl)- 1,2-epoxypropane, trans-1-(2,4-dichlorophenyl)-2-(pyrid-3-yl)- 1,2-epoxypropane, 1-(2,4-dichlorophenyl)-2-(pyrid-3-yl)- 1,2-epoxybutane and 2,4-dichloro- alpha -[1-hydroxy-1-(pyrid-3-yl)ethyl]- benzyl methanesulphonate … and the N-oxides and phytophysiologically acceptable salts with mineral acids, and metal complexes of I. … The compounds I are suitable as fungicides.

公开(公告)号：HUT52035A

公开(公告)日：1990-06-28

申请号：HU590189

申请日：1989-11-14

Applicant: BASF AG

Inventor： ZIPPLIES MATTHIAS ,  ZIPPERER BERNHARD ,  GOETZ NORBERT ,  SAUTER HUBERT ,  ROEHL FRANZ ,  LORENZ GISELA ,  AMMERMANN EBERHARD

IPC: A01N33/04 ,  A01N33/08 ,  A01N33/10 ,  A01N37/02 ,  A01N37/10 ,  A01N43/36 ,  A01N43/56 ,  A01N43/80 ,  A01N49/00 ,  A01N55/10 ,  C07C211/19 ,  C07C211/21 ,  C07C211/25 ,  C07C211/38 ,  C07C215/44 ,  C07C217/08 ,  C07C217/46 ,  C07C217/48 ,  C07C217/52 ,  C07C217/56 ,  C07C217/58 ,  C07C217/60 ,  C07C219/24 ,  C07C291/04 ,  C07C323/32 ,  C07D207/06 ,  C07D207/32 ,  C07D207/335 ,  C07D211/70 ,  C07D231/38 ,  C07D261/08 ,  C07D295/02 ,  C07D295/033 ,  C07F7/08 ,  C07D217/04 ,  C07D317/72 ,  C07D231/12 ,  C07D233/56 ,  C07D333/14 ,  A01N43/08 ,  A01N43/74

Abstract: 2-Aminodecalin derivatives of the formula I I where R1, R2 and R3 are H or methyl, A is H, OH, O-alkylcarbonyl, O-benzoyl or O-CH3, R4 is H, cyclopropyl, alkyl, alkenyl, or alkynyl, R5 is alkyl, alkenyl or alkynyl which is substituted or unsubstituted, cycloalkyl or cycloalkenyl whic is substituted or unsubstituted, substituted phenylalkyl, substituted cycloalkyl-alkyl, substituted 5-membered heterocyclic ring, bicycloalkyl-alkyl or R4 and R5, together with the nitrogen atom, are a substituted or unsubstituted, saturated or unsaturated piperidine radical, their plant-tolerated salts and N-oxides, and fungicides containing these compounds.

公开(公告)号：AT166393T

公开(公告)日：1998-06-15

申请号：AT94925459

申请日：1994-08-17

Applicant: BASF AG

Inventor： LADNER WOLFGANG ,  RETTENMAIER HANSJOERG ,  ZIPPERER BERNHARD ,  HANSEN HANSPETER

IPC: C12P7/52 ,  C07C51/09 ,  C07C53/19 ,  C12P7/40 ,  C12P41/00

Abstract: PCT No. PCT/EP94/02738 Sec. 371 Date Feb. 15, 1996 Sec. 102(e) Date Feb. 15, 1996 PCT Filed Aug. 17, 1994 PCT Pub. No. WO95/06130 PCT Pub. Date Mar. 2, 1995A process for the preparation of (L)-2-chloropropionic acid and its alkali metal, alkaline earth metal or ammonium salts which comprises hydrolyzing isobutyl L-chloropropionate at a pH of from 4 to 8 in the presence of a lipase from Pseudomonas spec. DSM 8246 and isolating the optically active reaction product from the reaction mixture either directly or after conversion of the salt into the acid in a conventional way, or further reacting it in situ. The optically active products are important intermediates for preparing crop protection agents.\!

公开(公告)号：ZA96387B

公开(公告)日：1997-06-18

申请号：ZA96387

申请日：1996-01-18

Applicant: BASF AG

Inventor： MERKLE HANS RUPERT ,  FRETSCHNER ERICH ,  HANSEN HANSPETER ,  ZIPPERER BERNHARD

IPC: C07B57/00 ,  C07C51/09 ,  C07C51/487 ,  C07C53/19 ,  C07C

Abstract: PCT No. PCT/EP96/00012 Sec. 371 Date Jan. 7, 1997 Sec. 102(e) Date Jan. 7, 1997 PCT Filed Jan. 4, 1996 PCT Pub. No. WO96/22272 PCT Pub. Date Jul. 25, 1996The present invention relates to a process for the preparation of optically active 2-halopropionic acids, in which the corresponding optically active alkyl 2-halopropionates are caused to react with a carboxylic acid at elevated temperature in a transacylation reaction with the formation of the optically active 2-halopropionic acid and the alkyl carboxylate, and the optically active 2-halopropionic acid obtained is separated from the reaction mixture. The optically active products produced are important intermediates for the preparation of plant protectants and pharmaceuticals.

公开(公告)号：AU4436896A

公开(公告)日：1996-08-07

申请号：AU4436896

申请日：1996-01-04

Applicant: BASF AG

Inventor： MERKLE HANS RUPERT ,  FRETSCHNER ERICH ,  HANSEN HANSPETER ,  ZIPPERER BERNHARD

IPC: C07B57/00 ,  C07C51/09 ,  C07C51/487 ,  C07C53/19

Abstract: PCT No. PCT/EP96/00012 Sec. 371 Date Jan. 7, 1997 Sec. 102(e) Date Jan. 7, 1997 PCT Filed Jan. 4, 1996 PCT Pub. No. WO96/22272 PCT Pub. Date Jul. 25, 1996The present invention relates to a process for the preparation of optically active 2-halopropionic acids, in which the corresponding optically active alkyl 2-halopropionates are caused to react with a carboxylic acid at elevated temperature in a transacylation reaction with the formation of the optically active 2-halopropionic acid and the alkyl carboxylate, and the optically active 2-halopropionic acid obtained is separated from the reaction mixture. The optically active products produced are important intermediates for the preparation of plant protectants and pharmaceuticals.

公开(公告)号：HU208612B

公开(公告)日：1993-12-28

申请号：HU828390

申请日：1990-12-14

Applicant: BASF AG

Inventor： SEELE RAINER ,  ZIPPERER BERNHARD ,  KEIL MICHAEL ,  GOETZ NORBERT ,  AMMERMANN EBERHARD ,  LORENZ GISELA ,  KOBER REINER ,  KUEKENHOEHNER THOMAS ,  HARREUS ALBRECHT ,  RADEMACHER WILHELM

IPC: A01N43/50 ,  A01N43/653 ,  C07D233/58 ,  C07D233/60 ,  C07D249/08 ,  C07D303/04 ,  C07D303/08 ,  C07D303/20 ,  C07D303/22 ,  C07D303/34 ,  C07D401/08 ,  C07D401/12 ,  C07D401/14 ,  C07D403/08 ,  C07D403/12 ,  C07D405/06 ,  C07D405/08 ,  C07D405/12 ,  C07D405/14 ,  C07D407/04 ,  C07D407/06 ,  C07D409/08 ,  C07D409/12 ,  C07D409/14 ,  C07D493/10 ,  C07D495/10 ,  C07D521/00 ,  C07D303/12

Abstract: Azolylmethylcycloalkanols of the general formula I in which R and R are identical or different and represent hydrogen or alkyl; R and R together represent or where Z is CH2, O, S, SO, SO2 or N-R ; R represents alkyl, phenyl, biphenyl, naphthyl, heteroaryl, benzyl or cycloalkyl, it being possible for each of these radicals to be substituted, and also tetrahydropyranyl; R and R in each case represent a hydrogen atom or an alkyl group; or in the event that R and R represent a together and additionally represent =CH-R ; R and R represent hydrogen or alkyl; or R and R together with the carbon atoms of which they are substituents represent a saturated or unsaturated 5- or 6-membered carbocyclic ring or R , R , R and R together with the carbon atoms of which they are substituents represent an optionally halogen-substituted phenyl ring or in the event that R and R are a R and R together can additionally represent =CH-R , R , R to R are hydrogen, alkyl, phenyl, biphenyl, naphthyl, heteroaryl, benzyl, dioxolanyl or cycloalkyl, it being possible for each of these radicals to be substituted; T represents the radical (CH2)n = CR , R O or S, n is an integer from 1 to 5, with the proviso that R to R do not simultaneously represent hydrogen, and with the proviso that R and R together do not represent when R to R and R to R represent hydrogen, and X represents the radical CH or N, and their acid addition salts and metal complexes which are tolerated by plants, and the fungicides and growth regulators containing these compounds.

公开(公告)号：NZ235192A

公开(公告)日：1993-05-26

申请号：NZ23519290

申请日：1990-09-06

Applicant: BASF AG

Inventor： SEELE RAINER ,  GOETZ NORBERT ,  KOBER REINER ,  ZIPPERER BERNHARD ,  AMMERMANN EBERHARD ,  LORENZ GISELA ,  GEBHARDT JOACHIM

IPC: C07D303/08 ,  A01N43/50 ,  A01N43/653 ,  C07D213/48 ,  C07D249/08 ,  C07D303/12 ,  C07D303/16 ,  C07D303/34 ,  C07D405/04 ,  C07D405/06 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07D417/14 ,  C07D521/00 ,  C07D409/04

Abstract: Azolylmethyloxiranes I … … (A and B are 5-/6-membered heteroaryl, alkyl, cycloalkyl, tetrahydropyranyl, tetrahydrothiopyranyl, phenyl, biphenyl, naphthyl or benzyl, it being possible for the substituents A and B to have a further one to three radicals, with the proviso that at least one of the substituents A or B is heteroaryl, unless B is an o-methylphenyl group; Z is CH or N),… and their acid addition salts and metal complexes,… with the exception of 2-(imidazol-1-ylmethyl)-2-(4-fluorophenyl)- 3-(pyrid-3-yl)-oxirane. … The compounds I are suitable as fungicides.

公开(公告)号：ZA914318B

公开(公告)日：1993-02-24

申请号：ZA914318

申请日：1991-06-06

Applicant: BASF AG

Inventor： WAGNER OLIVER ,  OLIVER WAGNER ,  ZIPPERER BERNHARD ,  BERNHARD ZIPPERER ,  GOETZ NORBERT ,  NORBERT GOETZ ,  KEIL MICHAEL ,  MICHAEL KEIL ,  AMMERMANN EBERHARD ,  EBERHARD AMMERMANN ,  LORENZ GISELA ,  GISELA LORENZ

IPC: A01N43/40 ,  C07D213/26 ,  C07D213/30 ,  C07D213/48 ,  C07D213/50 ,  C07D213/53 ,  C07D ,  A01N

Abstract: Beta-picoline derivs. (I) and their N-oxides and addn. salts are new. In (I), A = CR1R2; R1, R2 = H, 1-6C alkyl, 2-6C alkenyl or 2-6C alkynyl; or R1+R2 = 2-6C n-alkylene; B = CH2, CHOR3, CHR4 or C=NOR5; R3 = H, 1-6C alkyl, 1-6C haloalkyl, 3-8C cycloalkyl, 3-6C alkenyl, 2-6C acyl or phenyl, benzyl or benzoyl opt. mono-, di- or tri-substd. in the ring by 1-4C alkyl, 1-4C alkoxy, 1-4C haloalkyl, 1-4C haloalkoxy, halogen, cyano or nitro; R4 = H, F, Cl, Br or I; R5 = H, 1-6C alkyl, 1-6C haloalkyl, 3-7C cycloalkyl, 3-6C alkenyl or aryl-1-4C alkyl opt. mono-, di- or tri-substd. in the aryl ring by 1-4C alkyl, 1-4C alkoxy, 1-4C haloalkyl, halogen, cyano or nitro; Ar = phenyl or naphthyl opt. mono-, di- or tri-substd. by halogen, 1-6C alkyl, 1-4C alkoxy, 1-4C haloalkyl, 1-4C haloalkoxy, phenyl, phenoxy, halophenyl, halophenoxy or benzyloxy; except 1-phenyl-3-(3-pyridyl) propan-1-one (IA). The use of cpd. (IA), which is known from J. Org. Chem. 43 (1978), 3396 and Arch. Pharm. 307 (1974), 550, for the control of fungi is also claimed. Further, intermediates (II) are claimed except where A = CH2 or CH(CH3). 3 Cpds. (I), e.g., 2-ethyl-1-(4-fluorophenyl) -2-(pyridyl-3-methyl)butan-1-ol, are specifically claimed.