公开(公告)号：WO1994015727A1

公开(公告)日：1994-07-21

申请号：PCT/US1993009765

申请日：1993-10-13

Applicant: ISP INVESTMENTS INC.

Inventor： ISP INVESTMENTS INC. ,  FUSIAK, Frank

IPC: B08B03/04

CPC classification number: C11D7/5009 ,  C09D9/005 ,  C11D7/265 ,  C11D7/266 ,  C11D7/267 ,  C11D7/268 ,  C11D7/3209 ,  C11D7/3218 ,  C11D7/3281

Abstract: This invention is directed to an environmentally safe, water soluble stripping composition comprising between about 30 and about 98.5 wt. % N-methylpyrrolidone or a 10/90 to 90/10 mixture of N-methylpyrrolidone and gamma-butyrolactone and between about 0.1 and about 5 wt. % cyclomethicone. The invention also concerns the use of this composition in a process for stripping organic coatings such as paints, resins, varnishes and shellac from substrates.

Abstract translation: 本发明涉及环境安全的水溶性汽提组合物，其包含约30-约98.5重量％ ％N-甲基吡咯烷酮或10/90至90/10的N-甲基吡咯烷酮和γ-丁内酯的混合物和约0.1至约5wt。 ％环甲硅油。 本发明还涉及该组合物在从底物中剥离有机涂层如油漆，树脂，清漆和紫胶的方法中的应用。

公开(公告)号：WO1994010840A1

公开(公告)日：1994-05-26

申请号：PCT/US1993010115

申请日：1993-10-21

Applicant: ISP INVESTMENTS INC.

Inventor： ISP INVESTMENTS INC. ,  NARAYANAN, Kolazi, S. ,  CHAUDHURI, Ratan, K.

IPC: A01N25/10

CPC classification number: A01N37/22 ,  A01N25/10 ,  A01N37/26 ,  A01N2300/00

Abstract: Various liquid or low melting pesticide and herbicide formulations, previously formulated with organic solvents, are combined with a polymer in solution and co-precipitated to form a polymer complex which captures the pesticide or herbicide yet exists as a solid at ambient conditions. By preparing the pesticide or herbicide formulation as a solid complex, storage and handling of the formulation is possible without the potential for organic solvent emission. When the solid polymer complex is placed in water, a stable aqueous dispersion of the pesticide or herbicide is achieved as the polymer inhibits flocculation, with approximately 100 % recovery of the pesticide or herbicide. The figure is the graph showing recovery of an active ingredient after dispersion in a standing sample.

Abstract translation: 预先用有机溶剂配制的各种液体或低熔点农药和除草剂制剂与溶液中的聚合物组合并共沉淀以形成捕获农药或除草剂但在环境条件下作为固体存在的聚合物复合物。 通过制备作为固体复合物的农药或除草剂制剂，可以在没有潜在的有机溶剂排放的情况下储存和处理制剂。 当固体聚合物复合物置于水中时，由于聚合物抑制絮凝，农药或除草剂的回收率大约为100％，因此可获得稳定的农药或除草剂水分散体。 该图是显示在静置样品中分散后活性成分的回收率的图。

公开(公告)号：WO1993021931A1

公开(公告)日：1993-11-11

申请号：PCT/US1993003835

申请日：1993-04-23

Applicant: ISP INVESTMENTS INC.

Inventor： ISP INVESTMENTS INC. ,  SHIH, Jenn, S. ,  MERIANOS, John, J. ,  SMITH, Terry, E. ,  CHUANG, Jui-Chang ,  HALDAR, Rama, K.

IPC: A61K31/79

CPC classification number: A01N59/00 ,  A01N59/12 ,  C08F8/00 ,  A01N25/10 ,  A01N2300/00 ,  C08F26/10

Abstract: Strongly swellable, moderately crosslinked polyvinylpyrrolidone polymer in the form of fine white powders having a defined aqueous gel volume and Brookfield viscosity which is prepared by precipitation polymerization in the presence of a prescribed amount of a crosslinking agent, and an effective amount of a pharmaceutical medicament, or hydrogen peroxide or iodine in the form of a complex, is described herein.

Abstract translation: 强溶胀性中等交联聚乙烯吡咯烷酮聚合物，其为具有限定水凝胶体积和布氏粘度形式的细白色粉末，其通过在规定量的交联剂存在下的沉淀聚合制备，以及有效量的药物， 或复合物形式的过氧化氢或碘。

公开(公告)号：WO1993017787A1

公开(公告)日：1993-09-16

申请号：PCT/US1993001397

申请日：1993-02-18

Applicant: ISP INVESTMENTS INC.

Inventor： ISP INVESTMENTS INC. ,  ANDERSON, Lowell, R. ,  CHAUDHURI, Ratan, K. ,  LOGIN, Robert, B. ,  DE THOMAS, Waldo

IPC: B01J23/44

CPC classification number: C07D201/02 ,  B01J23/8926 ,  B01J23/8986 ,  C07D207/267 ,  C07D211/76 ,  C07D223/10

Abstract: A catalyst and method for producing N-substituted pyrrolidones utilizes a copper-palladium catalyst disposed on a support and mixed with a desired alcohol and 2-pyrrolidone. A reaction is undertaken under a hydrogen atmosphere, preferably at 50 to 1000 psig, and at a temperature ranging up to 400 DEG C. Utilizing a copper-palladium catalyst provides superior results in selectivity and yield over previous catalysts.

Abstract translation: 催化剂和制备N-取代的吡咯烷酮的方法利用设置在载体上的铜 - 钯催化剂并与所需的醇和2-吡咯烷酮混合。 反应在氢气氛下进行，优选在50-1000psig，温度范围达到400℃。使用铜 - 钯催化剂，提供优于先前催化剂的选择性和产率的优异结果。

公开(公告)号：WO1993016045A1

公开(公告)日：1993-08-19

申请号：PCT/US1993000765

申请日：1993-01-26

Applicant: ISP INVESTMENTS INC.

Inventor： ISP INVESTMENTS INC. ,  ANDERSON, Lowell, R. ,  CHAUDHURI, Ratan, K. ,  LOGIN, Robert, B.

IPC: C07D207/12

CPC classification number: C07D207/27 ,  A61K8/4913 ,  A61Q5/12 ,  A61Q19/00 ,  Y10S514/844

Abstract: A solution of stearamidopropyl dimethyl pyrrolidonyl methyl ammonium chloride in a polyhydric alcohol at a concentration of about 1-30 % by weight in glycerol.

公开(公告)号：WO1993009763A1

公开(公告)日：1993-05-27

申请号：PCT/US1992009821

申请日：1992-11-10

Applicant: ISP INVESTMENTS INC.

Inventor： ISP INVESTMENTS INC. ,  CHAUDHURI, Ratan, K. ,  JAISWAL, Dinesh, K. ,  HALDAR, Rama, K. ,  LOGIN, Robert, B. ,  TAZI, Mohammed ,  CHUANG, Jui-Chang

IPC: A61K09/14

CPC classification number: A61K9/2027

Abstract: A pharmaceutical tablet is provided herein having an effective dissolution rate. The tablet contains a pharmaceutically-active ingredient and a substantially linear, i.e. non-crosslinked K-30 to K-120 PVP, preferably above 116, as a binding agent. The PVP used herein preferably is made by a polymerization process in which the vinyl pyrrolidone monomer is polymerized in the presence of an initiator which produces a linear PVP polymerization, and a residual initiator level of less than 500 ppm.

Abstract translation: 本文提供了具有有效溶解速率的药片。 片剂含有药物活性成分和基本上线性的，即非交联的K-30至K-120 PVP，优选高于116，作为结合剂。 本文使用的PVP优选通过聚合方法制备，其中乙烯基吡咯烷酮单体在产生线性PVP聚合的引发剂存在下聚合，残余引发剂水平低于500ppm。

公开(公告)号：WO1993007251A1

公开(公告)日：1993-04-15

申请号：PCT/US1992006695

申请日：1992-08-12

Applicant: ISP INVESTMENTS INC.

Inventor： ISP INVESTMENTS INC. ,  MERIANOS, John, J.

IPC: C11D03/48

CPC classification number: C07C233/38 ,  A01N33/12 ,  C07C211/63 ,  C07C217/08 ,  C08K5/19 ,  A01N25/10 ,  A01N2300/00 ,  C08L39/06

Abstract: An antimicrobial, low toxicity, non-irritating composition comprises a blend of several bis-quaternary ammonium compounds optionally coprecipitated (1) with a copolymer of vinylpyrrolidone and an acrylamido or vinyl quaternary ammonium monomer, or (2) polyvinylpyrrolidone.

Abstract translation: 抗微生物，低毒性，无刺激性组合物包含任选地与乙烯基吡咯烷酮和丙烯酰胺或乙烯基季铵单体的共聚物共沉淀的几种双季铵化合物的混合物，或（2）聚乙烯吡咯烷酮。

公开(公告)号：WO1993006911A1

公开(公告)日：1993-04-15

申请号：PCT/US1992008060

申请日：1992-09-21

Applicant: ISP INVESTMENTS INC. ,  SHANBROM, Edward

Inventor： ISP INVESTMENTS INC. ,  LIEBERMAN, Herbert ,  MERIANOS, John, J.

IPC: B01D37/00

CPC classification number: A61M1/3687 ,  A61K35/16 ,  A61L2/0082 ,  A61L2/16

Abstract: A method is provided for treating blood and its compositions to remove pathogenic microorganisms present therein. The invention comprises contacting cross-linked polyvinylpyrrolidone-iodine (PVP-I2) with blood and separating the cross-linked PVP-iodine and the cells therein from the soluble portion of the blood. The preferred method involves loading cross-linked polyvinylpyrrolidone-iodine onto a filter having a porosity less than either the particle size of the cross-linked PVP-iodine or the blood cells in the composition, contacting the thus-loaded filter bed with the blood thereby to inactivate the microorganisms therein, passing the treated soluble portion of the blood composition through said filter, collecting the thus-treated blood cells remaining on the filter, and purifying the treated soluble portion of the blood composition by contacting it with cross-linked PVP to remove any residual iodine therein.

Abstract translation: 提供了一种治疗血液及其组合物以除去其中存在的病原微生物的方法。 本发明包括使交联聚乙烯吡咯烷酮碘（PVP-I2）与血液接触并将交联的PVP-碘及其中的细胞与血液的可溶部分分离。 优选的方法包括将交联的聚乙烯吡咯烷酮碘加载到孔隙率小于组合物中交联的PVP-碘或血液细胞的粒度的过滤器上，使过滤床与血液接触，从而 使其中的微生物灭活，使经处理的血液组合物的可溶部分通过所述过滤器，收集由此处理的过滤器上剩余的血液细胞，并通过与血液组合物的交联PVP与 清除其中残留的碘。

公开(公告)号：WO1993006816A1

公开(公告)日：1993-04-15

申请号：PCT/US1992007012

申请日：1992-08-24

Applicant: ISP INVESTMENTS INC.

Inventor： ISP INVESTMENTS INC. ,  KOPOLOW, Stephen, L. ,  TAZI, Mohammed ,  WALLS, Edward, W., Jr. ,  KWAK, Yoon, Tae ,  COHEN, Jeffrey, M.

IPC: A61K07/06

CPC classification number: A61K8/8164 ,  A61K8/046 ,  A61Q5/06

Abstract: The present invention relates to hair fixatives: (1) a terpolymer hair fixative comprising vinyl caprolactam, vinyl pyrrolidone and methacryloamidopropyl trimethylammonium chloride; or (2) vinyl caprolactam, vinyl pyrrolidone, dimethylaminoethyl methacrylate and acrylic acid; (3) vinyl caprolactam, vinyl pyrrolidone and vinyl acetate; and (4) a process of making a monomer mixture of maleic anhydride, vinyl acetate and isobornyl acrylate or methacrylate.

Abstract translation: 本发明涉及固定剂：（1）包含乙烯基己内酰胺，乙烯基吡咯烷酮和甲基丙烯酰氨基丙基三甲基氯化铵的三元共聚物固定剂; 或（2）乙烯基己内酰胺，乙烯基吡咯烷酮，甲基丙烯酸二甲基氨基乙酯和丙烯酸; （3）乙烯基己内酰胺，乙烯基吡咯烷酮和乙酸乙烯酯; 和（4）制备马来酸酐，乙酸乙烯酯和丙烯酸酯或甲基丙烯酸异冰片酯的单体混合物的方法。

公开(公告)号：WO1993001746A1

公开(公告)日：1993-02-04

申请号：PCT/US1992005515

申请日：1992-07-02

Applicant: ISP INVESTMENTS INC.

Inventor： ISP INVESTMENTS INC. ,  KWAK, Yoon, T. ,  KOPOLOW, Stephen, L. ,  TAZI, Mohammed

IPC: A61B05/0402

CPC classification number: A61K47/32 ,  A61B5/04087 ,  A61K9/0014

Abstract: What is provided herein is an electrically conductive gel composition for use in establishing a low resistance contact between an electrode and a biological body, comprising a clear, aqueous solution of about 0.1 to 3 % by weight of a crosslinked, neutralized copolymer of maleic anhydride and a C1-C5 alkyl vinyl ether. In the preferred form of the invention, the composition contains about 0.1 to 3 % by weight of the crosslinked, neutralized copolymer which contains about 1 to 5 mole % based on the alkyl vinyl ether of a crosslinking agent.