公开(公告)号：DE4213283A1

公开(公告)日：1993-10-28

申请号：DE4213283

申请日：1992-04-23

Applicant: BASF AG

Inventor： SCHADE CHRISTIAN DR ,  SANNER AXEL DR ,  WEKEL HANS-ULRICH DR ,  FROSCH FRANZ DR ,  WESTENFELDER HORST

IPC: A61K47/30 ,  A61K8/06 ,  A61K8/72 ,  A61K8/81 ,  A61K9/10 ,  A61K47/32 ,  A61Q19/00 ,  C08F20/02 ,  C08F20/10 ,  C08F20/26 ,  C08F220/02 ,  C08F220/04 ,  C08F220/06 ,  C08F220/20 ,  C08F220/28 ,  C08F222/00 ,  C08F222/02 ,  C08F222/04 ,  C08L33/02 ,  C09K23/52 ,  C08F220/08 ,  B01F17/52 ,  A61K7/00

Abstract: The use of copolymers obtainable by the radically initiated polymerisation of A) 50 to 99.9 wt % of an olefinically unsaturated C3 to C5 monocarboxylic acid, an olefinically unsaturated C4 to C8 bicarboxylic acid or its anhydride, or a mixture of such carboxylic acids or carboxylic acid anhydrides with B) 0.1 to 50 wt % of one or more long-chained compounds with isolated multiple C-C bonds from the group (1) mono or polyunsaturated C8 to C30 monocarboxylic acids which may have additional hydroxyl groups and their alkaline metal and earth alkaline metal salts, alkyl esters, amides, sorbitane esters, glycerine esters and polyglycerine esters, (2) mono or polyunsaturated aliphatic C8 to C30 amines, (3) mono or polyunsaturated C8 to C30 alcohols and esters thereof with saturated C1 to C4 monocarboxylic acids, (4) to (C8 to C30 alkyl) vinyl ether which may incorporate up to 25 alkylene oxide units, and (5) final and medium-position C13 to C30 alkenes; C) 0 to 49.9 wt % of other copolymerisable monomers, and D) 0 to 10 wt % of one or more compounds with at least two olefinically unsaturated groups in the molecule as cross-linking agents, as thickening or dispersing agents, especially in cosmetic and pharmaceutical preparations.

公开(公告)号：DE4018875A1

公开(公告)日：1991-12-19

申请号：DE4018875

申请日：1990-06-13

Applicant: BASF AG

Inventor： VOGEL FRIEDRICH DR ,  FROSCH FRANZ DR ,  WESTENFELDER HORST

IPC: A61K8/72 ,  A61K8/00 ,  A61K8/81 ,  A61K9/00 ,  A61K9/06 ,  A61K9/107 ,  A61K9/70 ,  A61K31/74 ,  A61K47/32 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q19/10

Abstract: The use of copolymers which are selectively hydrogenated on the olefinic double bond and are composed of …… A) 50 to 65% by weight of styrene, … B) 35 to 50% by weight of butadiene and … C) 0 to 5% by weight of other copolymerisable monomers … in cosmetic and pharmaceutical compositions.

公开(公告)号：ES2231923T3

公开(公告)日：2005-05-16

申请号：ES98114881

申请日：1998-08-07

Applicant: BASF AG

Inventor： KELLER HARALD ,  SCHEHLMANN VOLKER ,  WESTENFELDER HORST ,  PREISS THOMAS

IPC: A61K8/00 ,  A61K8/90 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q5/00 ,  A61Q17/04 ,  C08F216/14 ,  C08F216/16 ,  C08F216/18 ,  C08F218/00 ,  C08F218/10 ,  C08F220/36 ,  C09K3/00 ,  G02B1/04 ,  A61K7/42

Abstract: POLIMEROS ABSORBEDORES DE UV A BASE DE UNIDADES QUE SE MUESTRAN DE MANERA ESQUEMATICA EN LA FORMULA I EN DONDE LA SECUENCIA DE LAS UNIDADES ES COMO SE QUIERA, SIENDO LA SUMA DE A+B+C+D = 100 Y A TIENE UN VALOR DE 5 A 95, B UN VALOR DE 0 A 70, C UN VALOR DE 5 A 95, D UN VALOR DE 0 A 70 Y LOS RADICALES R TIENEN EL SIGNIFICADO INDICADO EN LA DESCRIPCION.

公开(公告)号：SI1046391T1

公开(公告)日：2005-04-30

申请号：SI200030535

申请日：2000-03-18

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  PRECHTL FRANK ,  WUENSCH THOMAS ,  WESTENFELDER HORST ,  HAREMZA SYLKE ,  BACH THORSTEN ,  SPIEGEL ANJA

IPC: C07D295/14 ,  A61K8/00 ,  A61K8/41 ,  A61K8/44 ,  A61K8/49 ,  A61K31/136 ,  A61K31/196 ,  A61K31/24 ,  A61K31/40 ,  A61P17/16 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C225/00 ,  C07C225/22 ,  C07C229/52 ,  C07D295/10 ,  C07D295/112 ,  C09K3/00 ,  A61K7/42

Abstract: Amino-substituted hydroxybenzophenones (I) are used as photostable UV filters in cosmetic and pharmaceutical compositions for protecting human skin or hair against solar radiation, optionally in combination with other UV absorbers. Amino-substituted hydroxybenzophenones of formula (I) are used as photostable UV filters in cosmetic and pharmaceutical compositions for protecting human skin or hair against solar radiation, optionally in combination with other UV absorbers. [Image] R1>, R2>H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl or 3-10C cycloalkenyl, or NR1>R2> is a 5- or 6-membered ring; R3>, R4>1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, 1-12C alkoxy, 1-20C alkoxycarbonyl, 1-12C alkylamino, 1-12C dialkylamino, aryl, heteroaryl, nitrile, carboxylate, sulfonate or ammonium; X : H, COOR5> or CONR6>R7>; R5>-R7>H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, (YO)oZ or aryl; Y : (CH2)x or CH(Me)CH2; x : 2-4; Z : Et, n-Pr, n-Bu or i-Pr; m : 0-3; n : 0-4; o : 1-20. Independent claims are also included for: (1) use of (I) as UV stabilizers in cosmetic and pharmaceutical compositions; (2) cosmetic and pharmaceutical compositions for protecting human skin or hair against UV light of wavelength 280-400 nm, comprising compounds (I) in a carrier, optionally in combination with other UV absorbers.

公开(公告)号：ES2228338T3

公开(公告)日：2005-04-16

申请号：ES00110475

申请日：2000-05-17

Applicant: BASF AG

Inventor： PRECHTL FRANK DR ,  HABECK THORSTEN DR ,  WESTENFELDER HORST ,  WUNSCH THOMAS DR

IPC: A61K8/00 ,  A61K8/30 ,  A61K8/35 ,  A61K8/368 ,  A61K8/37 ,  C07D311/58 ,  A61K8/40 ,  A61K8/49 ,  A61K47/08 ,  A61K47/14 ,  A61K47/16 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C255/34 ,  C07C261/02 ,  C07D311/04 ,  C07D495/04 ,  C08K5/07 ,  C08K5/1545 ,  C08K5/20 ,  C08K5/315 ,  C08K5/3435 ,  C08K5/42 ,  C08L101/00 ,  C09K3/00 ,  C09K15/06 ,  C09K15/16 ,  C09K15/20 ,  C09K15/30 ,  A61K7/42 ,  C08K5/16

Abstract: Empleo de compuestos de la **fórmula** en la que X significa un resto divalente del oxígeno, un resto carbonilo, imino en caso dado substituido de manera alifática o el resto -C(R9R10)-, Y significa grupo carbonilo o el resto -C(R9R10)-, R1 y R2 son restos iguales o diferentes, electrófilos, elegidos del grupo formado por ciano, alquil- o arilcarbonilo, alquiloxi- o ariloxicarbonilo, aminocarbonilo en caso dado substituido, alquil- o arilsufinilo, alquil- o arilsulfonilo y aminosulfonilo en caso dado substituido, R3 significa un átomo de hidrógeno, un grupo ciano, hidroxilo, carboxilo o aminocarbonilo o un resto alquilo con 1 a 20 átomos de carbono o un resto arilo con 5 a 20 átomos de carbono enlazados en caso dado a través de un puente de oxígeno, de un puente de aminocarbonilo o de un puente de oxicarbonilo, R4 significa un átomo de hidrógeno, un grupo hidroxilo, un grupo amino o un resto alquilo con 1 a 20 átomos de carbono o un resto arilo con 5 a 20 átomos de carbono enlazado en casodado a través de un puente de oxígeno y R5, R6, R9 y R10 significan, independientemente entre sí, hidrógeno o restos alquilo con 1 a 20 átomos de carbono, R7 y R8 significan, independientemente entre sí, hidrógeno o restos alquilo con 1 a 20 átomos de carbono o junto con el átomo de carbono ceteno significan un grupo carbonilo, como filtros fotoestables frente a los UV en preparaciones cosméticas para la protección de la piel humana y del cabello humano contra la irradiación solar, solos o junto con compuestos en sí conocidos para preparaciones cosméticas, absorbentes en el intervalo de los UV.

公开(公告)号：DE50104819D1

公开(公告)日：2005-01-20

申请号：DE50104819

申请日：2001-09-20

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  MATHAUER KLEMENS ,  WUENSCH THOMAS ,  WESTENFELDER HORST ,  ICHIHARA HIDEYUKI ,  IKEDA TAKAHIRO ,  DAUSCH WILMA M

IPC: A61K8/72 ,  A61K8/00 ,  A61K8/81 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q1/06 ,  A61Q1/08 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q3/02 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/10 ,  A61Q17/04 ,  C08F2/22 ,  C08F2/24 ,  C08F2/44 ,  C08K5/00 ,  C08L57/00 ,  A61K7/00

Abstract: Colorant-containing aqueous polymer dispersions comprise (all amounts by wt. of polymer matrix): (A) (i) a polymer matrix based on an ethylenically-unsaturated monomer (M); and (ii) an organic colorant comprising a dye or pigment, UV-absorber or optical brightener uniformly dispersed in the polymer matrix (0.5-50%); (B) a nonionic surfactant (0.1-20%); and (C) an amphiphilic polymer with 0.5-10 mol./kg anionic-functional groups (1-50%). An Independent claim is also included for preparation of the dispersions by: (i) dissolving the colorant in monomer M, (ii) emulsifying the mixture to give a conventional oil-in-water emulsion, (iii) homogenizing to give a mini-emulsion with monomer droplets of average diameter below 1,000 nm and then (iv) polymerizing the mini-emulsion in presence of a soluble free-radical initiator together with (B) (0.1-20 wt.%) and (C) (1-50 wt.%), each wt. being based on the wt. of M.

公开(公告)号：DE50007725D1

公开(公告)日：2004-10-21

申请号：DE50007725

申请日：2000-03-18

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  PRECHTL FRANK ,  WUENSCH THOMAS ,  WESTENFELDER HORST ,  HAREMZA SYLKE ,  BACH THORSTEN ,  SPIEGEL ANJA

IPC: C07D295/14 ,  A61K8/00 ,  A61K8/41 ,  A61K8/44 ,  A61K8/49 ,  A61K31/136 ,  A61K31/196 ,  A61K31/24 ,  A61K31/40 ,  A61P17/16 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C225/00 ,  C07C225/22 ,  C07C229/52 ,  C07D295/10 ,  C07D295/112 ,  C09K3/00 ,  A61K7/42

Abstract: Amino-substituted hydroxybenzophenones (I) are used as photostable UV filters in cosmetic and pharmaceutical compositions for protecting human skin or hair against solar radiation, optionally in combination with other UV absorbers. Amino-substituted hydroxybenzophenones of formula (I) are used as photostable UV filters in cosmetic and pharmaceutical compositions for protecting human skin or hair against solar radiation, optionally in combination with other UV absorbers. [Image] R1>, R2>H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl or 3-10C cycloalkenyl, or NR1>R2> is a 5- or 6-membered ring; R3>, R4>1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, 1-12C alkoxy, 1-20C alkoxycarbonyl, 1-12C alkylamino, 1-12C dialkylamino, aryl, heteroaryl, nitrile, carboxylate, sulfonate or ammonium; X : H, COOR5> or CONR6>R7>; R5>-R7>H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, (YO)oZ or aryl; Y : (CH2)x or CH(Me)CH2; x : 2-4; Z : Et, n-Pr, n-Bu or i-Pr; m : 0-3; n : 0-4; o : 1-20. Independent claims are also included for: (1) use of (I) as UV stabilizers in cosmetic and pharmaceutical compositions; (2) cosmetic and pharmaceutical compositions for protecting human skin or hair against UV light of wavelength 280-400 nm, comprising compounds (I) in a carrier, optionally in combination with other UV absorbers.

公开(公告)号：DE59810942D1

公开(公告)日：2004-04-15

申请号：DE59810942

申请日：1998-10-09

Applicant: BASF AG

Inventor： HABECK DR ,  HAREMZA DR ,  SCHEHLMANN DR ,  WESTENFELDER HORST ,  WUENSCH DR

IPC: A61K8/40 ,  A61K31/275 ,  A61Q1/04 ,  A61Q17/04 ,  A61K7/42

公开(公告)号：DE59807831D1

公开(公告)日：2003-05-15

申请号：DE59807831

申请日：1998-10-06

Applicant: BASF AG

Inventor： SCHEHLMANN VOLKER DR ,  WESTENFELDER HORST

IPC: A61K47/22 ,  A61K8/00 ,  A61K8/67 ,  A61K31/07 ,  A61Q5/00 ,  A61Q5/06 ,  A61Q19/00 ,  A61K7/00

Abstract: Ascorbyl-2'-phosphoric acid ester is used for preventing discoloration in cosmetic and pharmaceutical compositions containing vitamin A and/or vitamin A derivatives, without the lack of stability or unpleasant odour associated with known additives. The use of ascorbyl-2'-phosphoric acid ester is claimed for stabilizing vitamin A and/or vitamin A derivatives in cosmetic and pharmaceutical compositions.

公开(公告)号：DE59708700D1

公开(公告)日：2002-12-19

申请号：DE59708700

申请日：1997-08-13

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  AUMUELLER ALEXANDER ,  SCHEHLMANN VOLKER ,  WESTENFELDER HORST ,  WUENSCH THOMAS

IPC: A61K8/00 ,  A61K8/30 ,  A61K8/40 ,  A61K8/49 ,  A61K8/92 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C255/40 ,  C07D307/52 ,  C07D317/54 ,  C07D333/24 ,  A61K7/42

Abstract: The use of compounds of formula (I) as UV-A filters in cosmetic products (optionally in combination with standard UV absorbers) to protect the human skin against sunlight is claimed. R1-R3 = H or (cyclo)aliphatic group containing up to 18 C, or two of these groups can combine to form a 5 or 6-membered ring ; R4 = optionally substituted (hetero)aryl containing 5-12 ring atoms ; and R5 = R4 or H. Also claimed are (i) cosmetic products containing (I) for protecting the epidermis layer against UV radiation with a wavelength of 280-400 nm and (ii) compounds of formula (II) : R7-R9 = lower alkyl ; R6 = 2-thienyl (optionally substituted with lower alkyl), 4-(3,5-di-t-butyl)-1-hydroxyphenyl or 4-(3,5-di-t-butyl)-1-alkoxyphenyl.